EP4784994A1 - Analyse von vollblut mittels durchflusszytometrie - Google Patents

Analyse von vollblut mittels durchflusszytometrie

Info

Publication number
EP4784994A1
EP4784994A1 EP24787375.5A EP24787375A EP4784994A1 EP 4784994 A1 EP4784994 A1 EP 4784994A1 EP 24787375 A EP24787375 A EP 24787375A EP 4784994 A1 EP4784994 A1 EP 4784994A1
Authority
EP
European Patent Office
Prior art keywords
whole blood
constituents
data
flow cytometry
constituent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24787375.5A
Other languages
English (en)
French (fr)
Inventor
Andreas Boehmler
Nicole WEIT
Robert J. Zigon
Larry R. Myers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of EP4784994A1 publication Critical patent/EP4784994A1/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP24787375.5A 2023-09-26 2024-09-26 Analyse von vollblut mittels durchflusszytometrie Pending EP4784994A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363585449P 2023-09-26 2023-09-26
PCT/US2024/048635 WO2025072504A1 (en) 2023-09-26 2024-09-26 Analysis of whole blood using flow cytometry

Publications (1)

Publication Number Publication Date
EP4784994A1 true EP4784994A1 (de) 2026-08-05

Family

ID=93036998

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24787375.5A Pending EP4784994A1 (de) 2023-09-26 2024-09-26 Analyse von vollblut mittels durchflusszytometrie

Country Status (3)

Country Link
EP (1) EP4784994A1 (de)
CN (1) CN121844195A (de)
WO (1) WO2025072504A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4987086A (en) * 1987-11-30 1991-01-22 Becton, Dickinson And Company Method for analysis of subpopulations of cells
DE69329353T2 (de) * 1992-03-05 2001-01-04 Becton Dickinson And Co., Franklin Lakes Verfahren zur Herstellung und Analyse von Leukozyten in Vollblut unter Verwendung der Durchflusszytometrie
AU2002317418A1 (en) * 2001-07-11 2003-01-29 National Health Laboratory Service Cell enumeration
US20090105963A1 (en) * 2006-05-13 2009-04-23 Jesper Laursen Methods for Flow Cytometry Analyses of Un-Lysed Cells from Biological Fluids
WO2024072782A1 (en) 2022-09-28 2024-04-04 Beckman Coulter, Inc. Flow cytometry waveform processing

Also Published As

Publication number Publication date
WO2025072504A1 (en) 2025-04-03
CN121844195A (zh) 2026-04-10

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