EP4774760A2 - Verfahren und systeme zur automatisierten identifizierung von nichtkovalenter proteinbindung - Google Patents

Verfahren und systeme zur automatisierten identifizierung von nichtkovalenter proteinbindung

Info

Publication number
EP4774760A2
EP4774760A2 EP24789957.8A EP24789957A EP4774760A2 EP 4774760 A2 EP4774760 A2 EP 4774760A2 EP 24789957 A EP24789957 A EP 24789957A EP 4774760 A2 EP4774760 A2 EP 4774760A2
Authority
EP
European Patent Office
Prior art keywords
sample
protein
mass
mass spectrum
denaturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24789957.8A
Other languages
English (en)
French (fr)
Inventor
Hieu Cuong LE
Chang Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DH Technologies Development Pte Ltd
Original Assignee
DH Technologies Development Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DH Technologies Development Pte Ltd filed Critical DH Technologies Development Pte Ltd
Publication of EP4774760A2 publication Critical patent/EP4774760A2/de
Pending legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404—Capillaries used for transferring samples or ions

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
EP24789957.8A 2023-09-08 2024-09-06 Verfahren und systeme zur automatisierten identifizierung von nichtkovalenter proteinbindung Pending EP4774760A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363581438P 2023-09-08 2023-09-08
PCT/IB2024/058718 WO2025052328A2 (en) 2023-09-08 2024-09-06 Methods and systems for automated identification of protein non-covalent binding

Publications (1)

Publication Number Publication Date
EP4774760A2 true EP4774760A2 (de) 2026-07-15

Family

ID=93099957

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24789957.8A Pending EP4774760A2 (de) 2023-09-08 2024-09-06 Verfahren und systeme zur automatisierten identifizierung von nichtkovalenter proteinbindung

Country Status (2)

Country Link
EP (1) EP4774760A2 (de)
WO (1) WO2025052328A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5626889B2 (ja) 2007-09-19 2014-11-19 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 質量分析計用衝突セル
WO2024127359A1 (en) * 2022-12-16 2024-06-20 Dh Technologies Development Pte. Ltd. Methods and systems for automated identification of protein binders

Also Published As

Publication number Publication date
WO2025052328A2 (en) 2025-03-13
WO2025052328A3 (en) 2025-04-24

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