EP4774382A2 - Verfahren zur kontrolle des abbaus von polysorbat in biotherapeutischen formulierungen - Google Patents

Verfahren zur kontrolle des abbaus von polysorbat in biotherapeutischen formulierungen

Info

Publication number
EP4774382A2
EP4774382A2 EP24863479.2A EP24863479A EP4774382A2 EP 4774382 A2 EP4774382 A2 EP 4774382A2 EP 24863479 A EP24863479 A EP 24863479A EP 4774382 A2 EP4774382 A2 EP 4774382A2
Authority
EP
European Patent Office
Prior art keywords
hours
minutes
less
pharmaceutical composition
incubating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24863479.2A
Other languages
English (en)
French (fr)
Inventor
Ralf J. CARRILLO
Xuanwen Li
Taku TSUKIDATE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme LLC
Original Assignee
Merck Sharp & Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme LLC filed Critical Merck Sharp & Dohme LLC
Publication of EP4774382A2 publication Critical patent/EP4774382A2/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01013—Sterol esterase (3.1.1.13)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
EP24863479.2A 2023-09-08 2024-09-03 Verfahren zur kontrolle des abbaus von polysorbat in biotherapeutischen formulierungen Pending EP4774382A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363581328P 2023-09-08 2023-09-08
PCT/US2024/044968 WO2025054112A2 (en) 2023-09-08 2024-09-03 Methods to control polysorbate degradation in biotherapeutic formulations

Publications (1)

Publication Number Publication Date
EP4774382A2 true EP4774382A2 (de) 2026-07-15

Family

ID=94924074

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24863479.2A Pending EP4774382A2 (de) 2023-09-08 2024-09-03 Verfahren zur kontrolle des abbaus von polysorbat in biotherapeutischen formulierungen

Country Status (2)

Country Link
EP (1) EP4774382A2 (de)
WO (1) WO2025054112A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2946765T3 (pl) * 2014-05-23 2017-08-31 Ares Trading S.A. Ciekła kompozycja farmaceutyczna
MX2022010601A (es) * 2020-02-27 2022-09-09 Regeneron Pharma Analisis de proteinas de celula hospedera segun su actividad.

Also Published As

Publication number Publication date
WO2025054112A3 (en) 2025-05-01
WO2025054112A2 (en) 2025-03-13

Legal Events

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