EP4746969A1 - Heterozyklische pad4-inhibitoren - Google Patents

Heterozyklische pad4-inhibitoren

Info

Publication number
EP4746969A1
EP4746969A1 EP24755694.7A EP24755694A EP4746969A1 EP 4746969 A1 EP4746969 A1 EP 4746969A1 EP 24755694 A EP24755694 A EP 24755694A EP 4746969 A1 EP4746969 A1 EP 4746969A1
Authority
EP
European Patent Office
Prior art keywords
compound
disease
mmol
formulae described
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24755694.7A
Other languages
English (en)
French (fr)
Inventor
Makonen Belema
John A. Bender
Alyssa H. Antropow
Jason M. Guernon
Alan Xiangdong Wang
Daniel L. Cheney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of EP4746969A1 publication Critical patent/EP4746969A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
EP24755694.7A 2023-07-21 2024-07-19 Heterozyklische pad4-inhibitoren Pending EP4746969A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363514934P 2023-07-21 2023-07-21
PCT/US2024/038782 WO2025024288A1 (en) 2023-07-21 2024-07-19 Heterocyclic pad4 inhibitors

Publications (1)

Publication Number Publication Date
EP4746969A1 true EP4746969A1 (de) 2026-05-27

Family

ID=92424275

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24755694.7A Pending EP4746969A1 (de) 2023-07-21 2024-07-19 Heterozyklische pad4-inhibitoren

Country Status (5)

Country Link
EP (1) EP4746969A1 (de)
JP (1) JP2026524962A (de)
KR (1) KR20260040641A (de)
CN (1) CN122003422A (de)
WO (1) WO2025024288A1 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022013615A (es) 2020-04-30 2022-11-16 Gilead Sciences Inc Inhibidores de macrociclo de peptidilarginina deiminasas.

Also Published As

Publication number Publication date
WO2025024288A1 (en) 2025-01-30
CN122003422A (zh) 2026-05-08
WO2025024288A8 (en) 2026-02-05
KR20260040641A (ko) 2026-03-25
JP2026524962A (ja) 2026-07-24

Legal Events

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