EP4746869A2 - Modulatoren der neurodegeneration - Google Patents
Modulatoren der neurodegenerationInfo
- Publication number
- EP4746869A2 EP4746869A2 EP24843917.6A EP24843917A EP4746869A2 EP 4746869 A2 EP4746869 A2 EP 4746869A2 EP 24843917 A EP24843917 A EP 24843917A EP 4746869 A2 EP4746869 A2 EP 4746869A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- compound
- alkyl
- formula
- disease
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363527516P | 2023-07-18 | 2023-07-18 | |
| PCT/US2024/038402 WO2025019600A2 (en) | 2023-07-18 | 2024-07-17 | Modulators of neurodegeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP4746869A2 true EP4746869A2 (de) | 2026-05-27 |
Family
ID=94282566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24843917.6A Pending EP4746869A2 (de) | 2023-07-18 | 2024-07-17 | Modulatoren der neurodegeneration |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP4746869A2 (de) |
| JP (1) | JP2026524952A (de) |
| CN (1) | CN122249208A (de) |
| WO (1) | WO2025019600A2 (de) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PA8578101A1 (es) * | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
| JP2010502706A (ja) * | 2006-09-07 | 2010-01-28 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | キナーゼ阻害活性を有するフェネチルアミド誘導体 |
| US20170298056A1 (en) * | 2014-05-08 | 2017-10-19 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibitors of hiv-1 entry and methods of use thereof |
| CA3056970A1 (en) * | 2017-03-21 | 2018-09-27 | Bayer Pharma Aktiengesellschaft | 2-methyl-quinazolines |
-
2024
- 2024-07-17 WO PCT/US2024/038402 patent/WO2025019600A2/en not_active Ceased
- 2024-07-17 EP EP24843917.6A patent/EP4746869A2/de active Pending
- 2024-07-17 JP JP2026502814A patent/JP2026524952A/ja active Pending
- 2024-07-17 CN CN202480059339.0A patent/CN122249208A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN122249208A (zh) | 2026-06-19 |
| WO2025019600A3 (en) | 2025-02-27 |
| JP2026524952A (ja) | 2026-07-24 |
| WO2025019600A2 (en) | 2025-01-23 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20260306 |
|
| AK | Designated contracting states |
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