EP4740211A1 - Robuste quantifizierung von zirkulierender tumor-dna durch fragmentlängenanalyse - Google Patents

Robuste quantifizierung von zirkulierender tumor-dna durch fragmentlängenanalyse

Info

Publication number
EP4740211A1
EP4740211A1 EP24836437.4A EP24836437A EP4740211A1 EP 4740211 A1 EP4740211 A1 EP 4740211A1 EP 24836437 A EP24836437 A EP 24836437A EP 4740211 A1 EP4740211 A1 EP 4740211A1
Authority
EP
European Patent Office
Prior art keywords
ctdna
model
plasma sample
fragment length
samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24836437.4A
Other languages
English (en)
French (fr)
Inventor
Anders Martin Jacobsen SKANDERUP
Guanhua ZHU
Chowdhury Rafeed RAHMAN
Tan Bee Huat IAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agency for Science Technology and Research Singapore
Singapore Health Services Pte Ltd
Original Assignee
Agency for Science Technology and Research Singapore
Singapore Health Services Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency for Science Technology and Research Singapore, Singapore Health Services Pte Ltd filed Critical Agency for Science Technology and Research Singapore
Publication of EP4740211A1 publication Critical patent/EP4740211A1/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Data Mining & Analysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Primary Health Care (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP24836437.4A 2023-07-04 2024-07-04 Robuste quantifizierung von zirkulierender tumor-dna durch fragmentlängenanalyse Pending EP4740211A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10202301906V 2023-07-04
PCT/SG2024/050438 WO2025010031A1 (en) 2023-07-04 2024-07-04 Robust quantification of circulating tumour dna through fragment length analysis

Publications (1)

Publication Number Publication Date
EP4740211A1 true EP4740211A1 (de) 2026-05-13

Family

ID=94172582

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24836437.4A Pending EP4740211A1 (de) 2023-07-04 2024-07-04 Robuste quantifizierung von zirkulierender tumor-dna durch fragmentlängenanalyse

Country Status (2)

Country Link
EP (1) EP4740211A1 (de)
WO (1) WO2025010031A1 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3245713A1 (en) * 2022-03-17 2023-09-21 Delfi Diagnostics, Inc. CANCER SURVEILLANCE METHOD USING FRAGMENTATION PROFILES

Also Published As

Publication number Publication date
WO2025010031A1 (en) 2025-01-09

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