EP4728518A1 - Computerimplementiertes verfahren zur bestimmung eines wertes der allostatischen last eines menschen - Google Patents

Computerimplementiertes verfahren zur bestimmung eines wertes der allostatischen last eines menschen

Info

Publication number
EP4728518A1
EP4728518A1 EP24732333.0A EP24732333A EP4728518A1 EP 4728518 A1 EP4728518 A1 EP 4728518A1 EP 24732333 A EP24732333 A EP 24732333A EP 4728518 A1 EP4728518 A1 EP 4728518A1
Authority
EP
European Patent Office
Prior art keywords
biomarker
allostatic load
cpg
value
phenotype
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24732333.0A
Other languages
English (en)
French (fr)
Inventor
Sébastien NUSSLÉ
Semira GONSETH NUSSLÉ
Jonviea Danielle CHAMBERLAIN-CETTOU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genknowme SA
Original Assignee
Genknowme SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genknowme SA filed Critical Genknowme SA
Publication of EP4728518A1 publication Critical patent/EP4728518A1/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs

Landscapes

  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP24732333.0A 2023-06-15 2024-06-17 Computerimplementiertes verfahren zur bestimmung eines wertes der allostatischen last eines menschen Pending EP4728518A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23179588 2023-06-15
PCT/EP2024/066814 WO2024256726A1 (en) 2023-06-15 2024-06-17 Computer implemented method determining a value of allostatic load of a human being

Publications (1)

Publication Number Publication Date
EP4728518A1 true EP4728518A1 (de) 2026-04-22

Family

ID=86861813

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24732333.0A Pending EP4728518A1 (de) 2023-06-15 2024-06-17 Computerimplementiertes verfahren zur bestimmung eines wertes der allostatischen last eines menschen

Country Status (2)

Country Link
EP (1) EP4728518A1 (de)
WO (1) WO2024256726A1 (de)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5912147A (en) 1996-10-22 1999-06-15 Health Research, Inc. Rapid means of quantitating genomic instability
US6251594B1 (en) 1997-06-09 2001-06-26 Usc/Norris Comprehensive Cancer Ctr. Cancer diagnostic method based upon DNA methylation differences
DE19754482A1 (de) 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
EP0976835B1 (de) 1998-07-29 2003-07-09 Keygene N.V. Verfahren zur Erkennung von Nukleinsäuremethylierungen durch AFLP
US6605432B1 (en) 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
US6331393B1 (en) 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
EP1274865B1 (de) 2000-04-06 2007-02-14 Epigenomics AG Diagnose von mit apoptose assoziierten erkrankungen mittels ermittlung des methylierungszustandes von apoptose-assozierten genen
WO2002000926A2 (en) 2000-06-30 2002-01-03 Epigenomics Ag Diagnosis of diseases associated with signal transduction
US20050009059A1 (en) 2003-05-07 2005-01-13 Affymetrix, Inc. Analysis of methylation status using oligonucleotide arrays
US20050196792A1 (en) 2004-02-13 2005-09-08 Affymetrix, Inc. Analysis of methylation status using nucleic acid arrays
US20170251967A1 (en) 2016-03-04 2017-09-07 FlourishiQ Inc. System, apparatus and method for individualized stress management

Also Published As

Publication number Publication date
WO2024256726A1 (en) 2024-12-19

Similar Documents

Publication Publication Date Title
Ye et al. A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways
Yoshiji et al. Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity
Walsh et al. Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes
Wittenbrink et al. High-accuracy determination of internal circadian time from a single blood sample
Wojczynski et al. Definition of phenotype
Gianfrancesco et al. Obesity during childhood and adolescence increases susceptibility to multiple sclerosis after accounting for established genetic and environmental risk factors
Park et al. Assessment and diagnostic relevance of novel serum biomarkers for early decision of ST-elevation myocardial infarction
Alarcón et al. Systemic lupus erythematosus in three ethnic groups: II. Features predictive of disease activity early in its course
Gianfrancesco et al. Causal effect of genetic variants associated with body mass index on multiple sclerosis susceptibility
Pei et al. Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity
Lin et al. Methylome-wide association study of atrial fibrillation in Framingham Heart Study
Herder et al. The potential of novel biomarkers to improve risk prediction of type 2 diabetes
Karlson et al. Associations between human leukocyte antigen, PTPN22, CTLA4 genotypes and rheumatoid arthritis phenotypes of autoantibody status, age at diagnosis and erosions in a large cohort study
Herder et al. Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits
JP2014531202A (ja) 喫煙状態を判定するための方法および組成物
Gao et al. Comparative validation of an epigenetic mortality risk score with three aging biomarkers for predicting mortality risks among older adult males
Brenowitz et al. Extension of mendelian randomization to identify earliest manifestations of Alzheimer disease: association of genetic risk score for Alzheimer disease with lower body mass index by age 50 years
Lin et al. Whole blood gene expression associated with clinical biological age
Díaz et al. High inherited risk predicts age-associated increases in fibrosis in patients with MASLD
Balkhiyarova et al. Relationship between glucose homeostasis and obesity in early life—a study of Italian children and adolescents
Kim et al. Predicting risk of type 2 diabetes mellitus in Korean adults aged 40–69 by integrating clinical and genetic factors
Moerschel et al. Assessing the probability of risk factor control in patients with coronary heart disease: results from the ESC-EORP EUROASPIRE V survey
Prone-Olazabal et al. Metabolic syndrome: An overview on its genetic associations and gene–diet interactions
KR102348173B1 (ko) 제2형 당뇨병에 대한 유전적 위험도 측정 방법 및 분석 장치
Arts et al. Leucocyte telomere length is no molecular marker of physical frailty in late-life depression

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20260112

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR