EP4720658A2 - Signalverstärkung für massendetektion - Google Patents

Signalverstärkung für massendetektion

Info

Publication number
EP4720658A2
EP4720658A2 EP24816662.1A EP24816662A EP4720658A2 EP 4720658 A2 EP4720658 A2 EP 4720658A2 EP 24816662 A EP24816662 A EP 24816662A EP 4720658 A2 EP4720658 A2 EP 4720658A2
Authority
EP
European Patent Office
Prior art keywords
compounds
signal
mass spectrum
merged
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24816662.1A
Other languages
English (en)
French (fr)
Inventor
Ivan BAXTER
Louis CONNELLY
Allen HUBBARD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Donald Danforth Plant Science Center
Original Assignee
Donald Danforth Plant Science Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Donald Danforth Plant Science Center filed Critical Donald Danforth Plant Science Center
Publication of EP4720658A2 publication Critical patent/EP4720658A2/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8658—Optimising operation parameters

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
EP24816662.1A 2023-06-02 2024-06-03 Signalverstärkung für massendetektion Pending EP4720658A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363505941P 2023-06-02 2023-06-02
PCT/US2024/032259 WO2024250004A2 (en) 2023-06-02 2024-06-03 Signal amplification for mass detection

Publications (1)

Publication Number Publication Date
EP4720658A2 true EP4720658A2 (de) 2026-04-08

Family

ID=93658697

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24816662.1A Pending EP4720658A2 (de) 2023-06-02 2024-06-03 Signalverstärkung für massendetektion

Country Status (2)

Country Link
EP (1) EP4720658A2 (de)
WO (1) WO2024250004A2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8761465B2 (en) * 2009-03-18 2014-06-24 Microsoft Corporation Centroid processing
ES2982037T3 (es) * 2017-12-15 2024-10-14 Metabolon Inc Método para analizar componentes de moléculas pequeñas de una mezcla compleja, y aparato asociado y producto de programa informático
ES2767375B2 (es) * 2020-01-24 2020-12-17 Consorcio Centro De Investig Biomedica En Red M P Metodo , sistema y producto de programa para la identificacion de compuestos en muestras biologicas o ambientales complejas
EP4334714A4 (de) * 2021-05-07 2025-03-26 Donald Danforth Plant Science Center Verstärkung und detektion von zusammengesetzten signalen

Also Published As

Publication number Publication date
WO2024250004A3 (en) 2025-01-23
WO2024250004A2 (en) 2024-12-05

Similar Documents

Publication Publication Date Title
Kaufmann Combining UHPLC and high-resolution MS: a viable approach for the analysis of complex samples?
Gillette et al. Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry
Greaves et al. Mass spectrometry for the novice
Bowen et al. Dealing with the unknown: metabolomics and metabolite atlases
Yates III A century of mass spectrometry: from atoms to proteomes
Zhu et al. Mass spectrometry‐based label‐free quantitative proteomics
Lafaye et al. Metabolite profiling in rat urine by liquid chromatography/electrospray ion trap mass spectrometry. Application to the study of heavy metal toxicity
Telu et al. Analysis of human plasma metabolites across different liquid chromatography/mass spectrometry platforms: Cross‐platform transferable chemical signatures
US20180038831A1 (en) Systems and methods for integrating ion mobility and ion trap mass spectrometers
Cho et al. Targeting unique biological signals on the fly to improve MS/MS coverage and identification efficiency in metabolomics
Parshintsev et al. Methods for characterization of organic compounds in atmospheric aerosol particles
JP2007503594A (ja) メタボノミクスにおいてlc−msまたはlc−ms/msデータの処理を行うための方法およびデバイス
Li et al. Interpreting raw biological mass spectra using isotopic mass‐to‐charge ratio and envelope fingerprinting
LaMarche et al. MultiAlign: a multiple LC-MS analysis tool for targeted omics analysis
Oberacher et al. Compound identification in forensic toxicological analysis with untargeted LC–MS-based techniques
WO2003102543A2 (en) A method of using data binning in the analysis of chromatograhpy/spectrometry data
Armenta et al. Analytical methods to determine cocaine contamination of banknotes from around the world
US20240222101A1 (en) Amplification and detection of compound signals
Winkler Processing metabolomics and proteomics data with open software: a practical guide
US20140336951A1 (en) Identification of related peptides for mass spectrometry processing
Moses et al. Right in two: capabilities of ion mobility spectrometry for untargeted metabolomics
Helmeczi et al. A software tool for rapid and automated preprocessing of large-scale serum metabolomic data by multisegment injection-capillary electrophoresis-mass spectrometry
Gröger et al. Application of parallel computing to speed up chemometrics for GC× GC–TOFMS based metabolic fingerprinting
Ju et al. A graph density-based strategy for features fusion from different peak extract software to achieve more metabolites in metabolic profiling from high-resolution mass spectrometry
EP4720653A1 (de) Korrektur von drifteffekten in lc-ms-daten auf der basis der retentionszeit

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20251219

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR