EP4698317A1 - Système microfluidique - Google Patents

Système microfluidique

Info

Publication number
EP4698317A1
EP4698317A1 EP24718866.7A EP24718866A EP4698317A1 EP 4698317 A1 EP4698317 A1 EP 4698317A1 EP 24718866 A EP24718866 A EP 24718866A EP 4698317 A1 EP4698317 A1 EP 4698317A1
Authority
EP
European Patent Office
Prior art keywords
microchannel
magnetic
tip
fluid
actuator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24718866.7A
Other languages
German (de)
English (en)
Inventor
David GOSSELIN
Julien Autebert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inorevia
Original Assignee
Inorevia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inorevia filed Critical Inorevia
Publication of EP4698317A1 publication Critical patent/EP4698317A1/fr
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

L'invention concerne un système microfluidique (1000) comprenant un microcanal (21), une pompe (30) raccordée au microcanal (21) et conçue pour entraîner un fluide comprenant des particules magnétiques (31) le long dudit microcanal (21), au moins un dispositif de capture (100) comprenant un élément magnétique (101) conçu pour produire un champ magnétique avec une plage d'action fixe, ledit élément magnétique (101) comprenant une pointe magnétisable (11) et un aimant (12), au moins un actionneur (50a, 50b) conçu pour déplacer l'élément magnétique (101) par rapport au microcanal (21), le dispositif de capture (100) étant conçu pour adopter deux positions : une première position dans laquelle le microcanal (21) est compris dans la plage d'action du champ magnétique et les particules magnétiques (31) sont capturées et une seconde position dans laquelle le microcanal (21) est à l'extérieur de la plage d'action du champ magnétique et les particules magnétiques (31) sont libres.
EP24718866.7A 2023-04-21 2024-04-19 Système microfluidique Pending EP4698317A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23169296 2023-04-21
PCT/EP2024/060794 WO2024218337A1 (fr) 2023-04-21 2024-04-19 Système microfluidique

Publications (1)

Publication Number Publication Date
EP4698317A1 true EP4698317A1 (fr) 2026-02-25

Family

ID=86142816

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24718866.7A Pending EP4698317A1 (fr) 2023-04-21 2024-04-19 Système microfluidique

Country Status (3)

Country Link
EP (1) EP4698317A1 (fr)
CN (1) CN121240930A (fr)
WO (1) WO2024218337A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070031819A1 (en) * 2005-04-26 2007-02-08 University Of Washington Microfluidic systems for biological and molecular analysis and methods thereof
KR20100120128A (ko) * 2008-01-25 2010-11-12 루미넥스 코포레이션 솔레노이드 액츄에이터
WO2013041983A1 (fr) * 2011-09-19 2013-03-28 Centre National De La Recherche Scientifique Système micro-fluidique
EP3383534B1 (fr) * 2015-11-30 2019-08-21 Rqmicro AG Dispositif microfluidique, ensembles, et procédé d'extraction de particules à partir d'un échantillon
JP6999569B2 (ja) * 2016-04-01 2022-01-18 ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント 磁性マイクロ粒子を使用して大きな体積からより小さな体積に分析物を濃縮するためのｄｍｆ方法及びシステム
US12502673B2 (en) * 2019-06-14 2025-12-23 Sharp Life Science (Eu) Limited Magnetic particle extraction in an EWOD instrument

Also Published As

Publication number Publication date
CN121240930A (zh) 2025-12-30
WO2024218337A1 (fr) 2024-10-24

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