EP4580994A4 - Zusammensetzungen und verfahren zur verbesserung des stickoxidspiegels im intraoralen, nasalen und/oder nasopharyngealen bereich - Google Patents

Zusammensetzungen und verfahren zur verbesserung des stickoxidspiegels im intraoralen, nasalen und/oder nasopharyngealen bereich

Info

Publication number
EP4580994A4
EP4580994A4 EP23861519.9A EP23861519A EP4580994A4 EP 4580994 A4 EP4580994 A4 EP 4580994A4 EP 23861519 A EP23861519 A EP 23861519A EP 4580994 A4 EP4580994 A4 EP 4580994A4
Authority
EP
European Patent Office
Prior art keywords
nasopharyngal
intraoral
nasal
compositions
area
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23861519.9A
Other languages
English (en)
French (fr)
Other versions
EP4580994A1 (de
Inventor
Shawn J Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP4580994A1 publication Critical patent/EP4580994A1/de
Publication of EP4580994A4 publication Critical patent/EP4580994A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/08—Chewing gum characterised by the composition containing organic or inorganic compounds of the chewing gum base
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
EP23861519.9A 2022-08-30 2023-08-30 Zusammensetzungen und verfahren zur verbesserung des stickoxidspiegels im intraoralen, nasalen und/oder nasopharyngealen bereich Pending EP4580994A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263402149P 2022-08-30 2022-08-30
PCT/US2023/073152 WO2024050405A1 (en) 2022-08-30 2023-08-30 Compositions and methods for improving nitric oxide levels in intraoral, nasal and/or nasopharyngeal area

Publications (2)

Publication Number Publication Date
EP4580994A1 EP4580994A1 (de) 2025-07-09
EP4580994A4 true EP4580994A4 (de) 2026-08-12

Family

ID=90098708

Family Applications (1)

Application Number Title Priority Date Filing Date
EP23861519.9A Pending EP4580994A4 (de) 2022-08-30 2023-08-30 Zusammensetzungen und verfahren zur verbesserung des stickoxidspiegels im intraoralen, nasalen und/oder nasopharyngealen bereich

Country Status (4)

Country Link
EP (1) EP4580994A4 (de)
JP (1) JP2025529198A (de)
CN (1) CN120187671A (de)
WO (1) WO2024050405A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4687469A1 (de) * 2023-03-24 2026-02-11 Wm. Wrigley Jr. Company Zusammensetzungen mit nitratreichen lebensmitteln und extrakten zur verlagerung des oralen mikrobioms

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9610311B2 (en) * 2013-06-28 2017-04-04 Arjuna Natural Extracts, Ltd. Medicinal composition of amaranth extract having enriched nitrate content and a method of preparing the same
US20190083528A1 (en) * 2008-06-13 2019-03-21 Board Of Regents, The University Of Texas System Nitrite formulations and their use as nitric oxide prodrugs
WO2019099003A2 (en) * 2017-11-15 2019-05-23 Berkeley Nox Limited Novel dietary supplements
US20200352986A1 (en) * 2018-05-20 2020-11-12 Shawn J. Green Methods and compositions for alleviating respiratory dysfunction
WO2021122741A2 (en) * 2019-12-17 2021-06-24 Fundación Para El Fomento De La Investigación Sanitaria Y Biomédica De La Comunitat Valenciana Prebiotic and probiotic treatment to reduce oral dysbiosis and promote eubiosis
US20220000953A1 (en) * 2018-11-05 2022-01-06 Marcus Kruse Antihypertensive Composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE282326T1 (de) * 1998-03-04 2004-12-15 Dandy As Beschichteter kaugummi, verfahren zur herstellung und verwendung von einem oder mehreren festen aktiven stoffen
US7407986B2 (en) * 2001-12-18 2008-08-05 Brassica Foundation For Chemoprotection Research, Inc. Prevention and treatment of oxidative stress disorders by glutathione and phase II detoxification enzymes
PE20180026A1 (es) * 2015-01-27 2018-01-09 Florengale Llc Composicion topica curativa
US20170304164A1 (en) * 2016-04-21 2017-10-26 Berkeley Nox Limited Compositions, apparatus and methods for monitoring and improving oral health
US10624921B2 (en) * 2016-11-15 2020-04-21 Berkeley Nox Limited Dietary supplements

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190083528A1 (en) * 2008-06-13 2019-03-21 Board Of Regents, The University Of Texas System Nitrite formulations and their use as nitric oxide prodrugs
US9610311B2 (en) * 2013-06-28 2017-04-04 Arjuna Natural Extracts, Ltd. Medicinal composition of amaranth extract having enriched nitrate content and a method of preparing the same
WO2019099003A2 (en) * 2017-11-15 2019-05-23 Berkeley Nox Limited Novel dietary supplements
US20200352986A1 (en) * 2018-05-20 2020-11-12 Shawn J. Green Methods and compositions for alleviating respiratory dysfunction
US20220000953A1 (en) * 2018-11-05 2022-01-06 Marcus Kruse Antihypertensive Composition
WO2021122741A2 (en) * 2019-12-17 2021-06-24 Fundación Para El Fomento De La Investigación Sanitaria Y Biomédica De La Comunitat Valenciana Prebiotic and probiotic treatment to reduce oral dysbiosis and promote eubiosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2024050405A1 *

Also Published As

Publication number Publication date
EP4580994A1 (de) 2025-07-09
CN120187671A (zh) 2025-06-20
WO2024050405A1 (en) 2024-03-07
JP2025529198A (ja) 2025-09-04

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RIC1 Information provided on ipc code assigned before grant

Ipc: C01D 9/00 20060101AFI20260707BHEP

Ipc: A23G 4/08 20060101ALI20260707BHEP

Ipc: A61K 31/375 20060101ALI20260707BHEP

Ipc: A61K 9/68 20060101ALI20260707BHEP

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Ipc: A61K 45/06 20060101ALI20260707BHEP

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Ipc: A61K 36/23 20060101ALI20260707BHEP