EP4408446A4 - Nerventransplantatsysteme, -vorrichtungen und -verfahren - Google Patents

Nerventransplantatsysteme, -vorrichtungen und -verfahren

Info

Publication number
EP4408446A4
EP4408446A4 EP22877378.4A EP22877378A EP4408446A4 EP 4408446 A4 EP4408446 A4 EP 4408446A4 EP 22877378 A EP22877378 A EP 22877378A EP 4408446 A4 EP4408446 A4 EP 4408446A4
Authority
EP
European Patent Office
Prior art keywords
methods
devices
nerve graft
graft systems
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22877378.4A
Other languages
English (en)
French (fr)
Other versions
EP4408446A2 (de
Inventor
Lorenzo Soletti
Nicole Cwalina
Brandon Burger
Anne E Faust
Sydney E Borcherding
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Renerva LLC
Original Assignee
Renerva LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renerva LLC filed Critical Renerva LLC
Publication of EP4408446A2 publication Critical patent/EP4408446A2/de
Publication of EP4408446A4 publication Critical patent/EP4408446A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
EP22877378.4A 2021-09-30 2022-09-30 Nerventransplantatsysteme, -vorrichtungen und -verfahren Pending EP4408446A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202163250379P 2021-09-30 2021-09-30
US202163295642P 2021-12-31 2021-12-31
US202263329597P 2022-04-11 2022-04-11
PCT/US2022/045365 WO2023056008A2 (en) 2021-09-30 2022-09-30 Nerve graft systems, devices, and methods

Publications (2)

Publication Number Publication Date
EP4408446A2 EP4408446A2 (de) 2024-08-07
EP4408446A4 true EP4408446A4 (de) 2025-09-03

Family

ID=85783522

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22877378.4A Pending EP4408446A4 (de) 2021-09-30 2022-09-30 Nerventransplantatsysteme, -vorrichtungen und -verfahren

Country Status (5)

Country Link
EP (1) EP4408446A4 (de)
AU (1) AU2022353834A1 (de)
CA (1) CA3232270A1 (de)
IL (1) IL311272A (de)
WO (1) WO2023056008A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025144768A1 (en) * 2023-12-27 2025-07-03 Renerva, Llc Nerve graft systems, devices, and methods
CN120393122A (zh) * 2025-05-09 2025-08-01 广州中大医疗器械有限公司 一种去细胞同种异体神经修复材料的保存方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE543509T1 (de) * 2001-08-13 2012-02-15 Univ Florida Material und verfahren zur förderung der reparatur von nervengewebe
WO2008109407A2 (en) 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
WO2014138351A1 (en) 2013-03-06 2014-09-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Injectable peripheral nerve specific hydrogel
EP3698815B1 (de) 2014-03-21 2024-02-21 University of Pittsburgh- Of the Commonwealth System of Higher Education Endgültig sterilisierter hydrogel aus einer extrazellulären matrix
CA3154767A1 (en) * 2019-09-30 2021-04-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix devices and methods of manufacture
EP4084835A4 (de) 2019-12-30 2024-01-17 Renerva, LLC Extrazelluläre matrixsysteme, vorrichtungen und verfahren zum einsatz

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "SBIR Phase I: Development of a Peripheral Nerve Matrix Conduit to Enable Nerve Regeneration", NSF AWARDS, 30 June 2021 (2021-06-30), XP093065604, Retrieved from the Internet <URL:https://www.nsf.gov/awardsearch/showAward?AWD_ID=1913761&HistoricalAwards=false> [retrieved on 20230720] *

Also Published As

Publication number Publication date
WO2023056008A3 (en) 2023-05-11
AU2022353834A1 (en) 2024-04-18
WO2023056008A2 (en) 2023-04-06
IL311272A (en) 2024-05-01
CA3232270A1 (en) 2023-04-06
EP4408446A2 (de) 2024-08-07

Similar Documents

Publication Publication Date Title
IL293061B1 (en) Cooperative networking systems, methods and devices
IL288447A (en) Systems, devices, and methods for treating heart valves
EP4323053A4 (de) Systeme und verfahren zur stimulierung von zwei oder mehr nervenzweigen
EP3969580A4 (de) Vorrichtungen, verfahren und systeme zur elektroporation
EP4093352A4 (de) Vorrichtungen, systeme und verfahren für die otologie
EP4415798A4 (de) Vorrichtungen, systeme und verfahren zur hautbehandlung
EP3982778B8 (de) System und verfahren zur verwaltung einer rauchersatzvorrichtung
EP4013481A4 (de) System, verfahren und vorrichtungen zur rückenmarkstimulation
EP4052063A4 (de) Systeme, vorrichtungen und verfahren zur synchronisation
IL279421A (en) System, applicator and method for implants
SG11202107634VA (en) Devices, systems, methods and assemblies for medical electrodes
EP4025991A4 (de) Räumlich-zeitliche fusionierte multiplikation-addition sowie verwandte systeme, verfahren und vorrichtungen
EP4090253A4 (de) Gewebebehandlungsvorrichtungen, -systeme und -verfahren
EP4408446A4 (de) Nerventransplantatsysteme, -vorrichtungen und -verfahren
GB2617982B (en) Exosome systems, prducts and methods
EP3989887A4 (de) Obesitasbehandlungsvorrichtungen, -systeme und -verfahren
IL316448A (en) Screening devices, systems and methods
GB2597009B (en) Microphone configurations for eyewear devices, systems, apparatuses, and methods
EP3873592A4 (de) Systeme, vorrichtungen und verfahren zur implantierbaren neuromodulationsstimulation
EP4369904A4 (de) Behandlungssysteme und zugehörige verfahren
EP4288138A4 (de) Systeme, verfahren und vorrichtungen für elektrische stimulationstherapie
EP3634313A4 (de) Endovaskuläre systeme, vorrichtungen und verfahren zur platzierung einer verzweigungsvorrichtung in einem kanal eines haupttransplantats
EP4165388A4 (de) Mikrofluidische vorrichtungen, systeme und verfahren
EP4090413A4 (de) Systeme und verfahren zur stimulation
IL277195A (en) Implantation devices, system and methods

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20240429

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20250804

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 35/30 20150101AFI20250729BHEP

Ipc: A61F 2/07 20130101ALI20250729BHEP

Ipc: A61L 27/36 20060101ALI20250729BHEP

Ipc: A61L 27/50 20060101ALI20250729BHEP