EP4401622A4 - Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung - Google Patents

Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung

Info

Publication number
EP4401622A4
EP4401622A4 EP22870452.4A EP22870452A EP4401622A4 EP 4401622 A4 EP4401622 A4 EP 4401622A4 EP 22870452 A EP22870452 A EP 22870452A EP 4401622 A4 EP4401622 A4 EP 4401622A4
Authority
EP
European Patent Office
Prior art keywords
neurodegeneration
wearable device
invasive assessment
glymphatic flow
glymphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22870452.4A
Other languages
English (en)
French (fr)
Other versions
EP4401622A1 (de
Inventor
Paul Dagum
Gregory T A Kovacs
Laurent B Giovangrandi
Carl J Weber
Joerg C Student
Nathan Whipple
Jonathan I Kaplan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Cognition Inc
Original Assignee
Applied Cognition Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Cognition Inc filed Critical Applied Cognition Inc
Publication of EP4401622A1 publication Critical patent/EP4401622A1/de
Publication of EP4401622A4 publication Critical patent/EP4401622A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006—ECG or EEG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/372—Analysis of electroencephalograms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4806—Sleep evaluation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6815—Ear
    • A61B5/6817—Ear canal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/166—Details of sensor housings or probes; Details of structural supports for sensors the sensor is mounted on a specially adapted printed circuit board
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Primary Health Care (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Child & Adolescent Psychology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Developmental Disabilities (AREA)
  • Business, Economics & Management (AREA)
  • General Business, Economics & Management (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
EP22870452.4A 2021-09-14 2022-04-05 Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung Pending EP4401622A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163244080P 2021-09-14 2021-09-14
PCT/US2022/023409 WO2023043490A1 (en) 2021-09-14 2022-04-05 Non-invasive assessment of glymphatic flow and neurodegeneration from a wearable device

Publications (2)

Publication Number Publication Date
EP4401622A1 EP4401622A1 (de) 2024-07-24
EP4401622A4 true EP4401622A4 (de) 2025-07-09

Family

ID=83695526

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22870452.4A Pending EP4401622A4 (de) 2021-09-14 2022-04-05 Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung

Country Status (5)

Country Link
US (4) US11478184B1 (de)
EP (1) EP4401622A4 (de)
JP (1) JP2024535131A (de)
AU (1) AU2022344928A1 (de)
WO (1) WO2023043490A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7088153B2 (ja) * 2019-09-19 2022-06-21 カシオ計算機株式会社 Ｃａｐ（周期性脳波活動）検出装置、ｃａｐ（周期性脳波活動）検出方法及びプログラム
EP4401622A4 (de) * 2021-09-14 2025-07-09 Applied Cognition Inc Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung
US12013724B1 (en) * 2022-05-27 2024-06-18 OpenBCI, Inc. Multi-layer headgear system
US12004874B2 (en) 2022-10-24 2024-06-11 Applied Cognition, Inc. Wearable device and method for non-invasive assessment of glymphatic flow
WO2024211033A2 (en) * 2023-03-02 2024-10-10 William Marsh Rice University Methods and devices for the non-invasive assessment of cerebro-spinal dynamics and diagnosis of brain pathophysiologies
KR20240172131A (ko) * 2023-05-31 2024-12-09 서울대학교병원 대뇌 아교임파계 활성 정보 제공 방법 및 장치
CN117547260A (zh) * 2024-01-11 2024-02-13 浙江普可医疗科技有限公司 基于睡眠脑电波的血糖预测方法、系统、设备及存储介质
CN119074007A (zh) * 2024-08-14 2024-12-06 同济大学 一种神经退行疾病评估方法、装置、设备以及存储介质

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190380648A1 (en) * 2017-02-21 2019-12-19 Bose Corporation Collecting biologically-relevant information using an earpiece
WO2020210813A1 (en) * 2019-04-11 2020-10-15 The General Hospital Corporation Generating imaging-based neurological state biomarkers and estimating cerebrospinal fluid (csf) dynamics based on coupled neural and csf oscillations during sleep

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4601294A (en) * 1982-01-25 1986-07-22 Minnesota Mining And Manufacturing Company Ear canal electrode
US4706682A (en) * 1985-08-21 1987-11-17 Minnesota Mining And Manufacturing Company External ear canal electrode to be placed proximate the tympanic membrane
US6640121B1 (en) 1999-08-10 2003-10-28 The University Of Miami Otic microprobe for neuro-cochlear monitoring
JP2001137196A (ja) * 1999-11-15 2001-05-22 Yoshinobu Nakamura 頭部血流バランス検査装置
US8211031B2 (en) * 2002-01-15 2012-07-03 Orsan Medical Technologies Ltd. Non-invasive intracranial monitor
KR100571811B1 (ko) 2003-05-09 2006-04-17 삼성전자주식회사 귀속형 생체 신호 측정 장치
WO2005020841A2 (en) * 2003-08-25 2005-03-10 Sarnoff Corporation Monitoring using signals detected from auditory canal
US20070112277A1 (en) 2005-10-14 2007-05-17 Fischer Russell J Apparatus and method for the measurement and monitoring of bioelectric signal patterns
WO2008005440A2 (en) * 2006-06-30 2008-01-10 University Of Illinois Monitoring and controlling hydrocephalus
US8652040B2 (en) 2006-12-19 2014-02-18 Valencell, Inc. Telemetric apparatus for health and environmental monitoring
WO2010041206A1 (en) * 2008-10-07 2010-04-15 Orsan Medical Technologies Ltd. Diagnosis of acute strokes
AU2009348759B2 (en) 2009-06-26 2013-10-03 T&W Engineering A/S EEG monitoring apparatus and method for presenting messages therein
WO2011000375A1 (en) 2009-07-02 2011-01-06 Widex A/S An ear plug with surface electrodes
SG177606A1 (en) 2009-07-13 2012-03-29 Widex As A hearing aid adapted fordetecting brain waves and a method for adapting such a hearing aid
AU2009356089A1 (en) 2009-12-02 2012-06-14 Widex A/S Method and apparatus for alerting a person carrying an EEG assembly
KR101533874B1 (ko) 2010-02-01 2015-07-03 비덱스 에이/에스 무선 통신을 구비한 휴대용 ｅｅｇ 모니터 시스템
US9345411B2 (en) * 2011-02-09 2016-05-24 Orsan Medical Technologies, Ltd. Devices and methods for monitoring cerebral hemodynamic conditions
WO2012130249A1 (en) * 2011-03-31 2012-10-04 Aarhus Universitet System for assessing tissue substance extraction
KR101688704B1 (ko) 2011-08-24 2016-12-21 티앤더블유 엔지니어링 에이/에스 용량성 전극을 구비한 eeg 모니터 및 뇌파 모니터링 방법
US8700116B2 (en) * 2011-09-29 2014-04-15 Covidien Lp Sensor system with pressure application
WO2013109389A1 (en) * 2012-01-16 2013-07-25 Valencell, Inc. Physiological metric estimation rise and fall limiting
US9272118B1 (en) 2012-03-02 2016-03-01 George Acton Methods for treating brain malfunctions
EP2964270A4 (de) * 2013-02-21 2017-03-22 University Of Rochester Verfahren zur beurteilung der hirnweiten paravaskulären bahn für drainagefunktion und darauf basierende verfahren zur behandlung von neurodegenerativen störungen
EP3917167A3 (de) 2013-06-14 2022-03-09 Oticon A/s Hörhilfevorrichtung mit Gehirn-Computer-Schnittstelle
DE102014100824A1 (de) 2014-01-24 2015-07-30 Nikolaj Hviid Eigenständiger Multifunktionskopfhörer für sportliche Aktivitäten
EP3097702A1 (de) 2014-01-24 2016-11-30 Bragi GmbH Multifunktionskopfhörersystem für sportliche aktivitäten
US10542904B2 (en) 2014-04-23 2020-01-28 Case Western Reserve University Systems and methods for at home neural recording
EP2986029A1 (de) 2014-08-14 2016-02-17 Oticon A/s Verfahren und System zur Modellierung einer maßgefertigten Otoplastik
WO2016074103A1 (en) 2014-11-14 2016-05-19 Neurochip Corporation Method and apparatus for processing electroencephalogram (eeg) signals
CN107106092A (zh) 2015-01-19 2017-08-29 T W工程公司 用于调整个人的血糖水平的系统和方法
US20180020937A1 (en) 2015-01-26 2018-01-25 Chang-An Chou Wearable electrocardiographic measurement device
US20180014741A1 (en) 2015-01-26 2018-01-18 Chang-An Chou Wearable physiological monitoring device
AU2016218989B2 (en) 2015-02-13 2020-09-10 Noopl, Inc. System and method for improving hearing
WO2016132176A1 (en) 2015-02-19 2016-08-25 Synaptive Medical (Barbados) Inc. Systems and methods for measuring global glymphatic flow using magnetic resonance imaging
CA2983197C (en) 2015-05-04 2020-06-30 T&W Engineering A/S Eeg monitor with a housing individually fitted to a person
US10194228B2 (en) 2015-08-29 2019-01-29 Bragi GmbH Load balancing to maximize device function in a personal area network device system and method
DK3355760T3 (da) 2015-10-01 2021-06-07 T&W Eng A/S Øregangsprop til at detektere bioelektriske signaler og fremgangsmåde til fremstilling
DK3888564T3 (da) 2015-10-02 2025-07-14 Earlens Corp Indretning til tilpasset afgivelse af medicin i øregangen
US20190223747A1 (en) 2016-01-22 2019-07-25 Chang-An Chou Wearable physiological activity sensor, sensing device, and sensing system
US10052065B2 (en) 2016-03-23 2018-08-21 Bragi GmbH Earpiece life monitor with capability of automatic notification system and method
US20170347177A1 (en) 2016-05-25 2017-11-30 Smartear, Inc. In-Ear Utility Device Having Sensors
US11426577B2 (en) * 2016-08-26 2022-08-30 Wisconsin Alumni Research Foundation Neuromodulation to modulate glymphatic clearance
US10617297B2 (en) 2016-11-02 2020-04-14 Bragi GmbH Earpiece with in-ear electrodes
JP6852162B2 (ja) 2016-12-09 2021-03-31 ティ・オ・ドォッブルビィ・エンジニアリング・アー／エス 電極を備える汎用イヤー・デバイス
US10275027B2 (en) 2017-01-23 2019-04-30 Naqi Logics, Llc Apparatus, methods, and systems for using imagined direction to define actions, functions, or execution
US11380430B2 (en) 2017-03-22 2022-07-05 Bragi GmbH System and method for populating electronic medical records with wireless earpieces
US11694771B2 (en) 2017-03-22 2023-07-04 Bragi GmbH System and method for populating electronic health records with wireless earpieces
US10918325B2 (en) 2017-03-23 2021-02-16 Fuji Xerox Co., Ltd. Brain wave measuring device and brain wave measuring system
US11013445B2 (en) 2017-06-08 2021-05-25 Bragi GmbH Wireless earpiece with transcranial stimulation
US20180368718A1 (en) 2017-06-21 2018-12-27 Jeffrey E. Koziol Smart Headphones
US10575777B2 (en) 2017-08-18 2020-03-03 Bose Corporation In-ear electrical potential sensor
EP3492002A1 (de) 2017-12-01 2019-06-05 Oticon A/s Hörhilfesystem
US20190209038A1 (en) 2018-01-09 2019-07-11 Holland Bloorview Kids Rehabilitation Hospital In-ear eeg device and brain-computer interfaces
EP3525490B1 (de) 2018-02-13 2025-05-07 Oticon A/s In-ohr-hörgerät, hörgerät und elektro-akustischer wandler
US11019417B2 (en) 2018-02-28 2021-05-25 Starkey Laboratories, Inc. Modular hearing assistance device
WO2019241645A1 (en) 2018-06-15 2019-12-19 Newton Howard Device for monitoring activities of daily living and physiological parameters to determine a condition and diagnosis of the human brain and body
WO2020035852A2 (en) 2018-08-14 2020-02-20 Neurotrigger Ltd. Method and apparatus for transcutaneous facial nerve stimulation and applications thereof
WO2020061209A1 (en) 2018-09-18 2020-03-26 Biointellisense, Inc. Validation, compliance, and/or intervention with ear device
EP3873328A1 (de) 2018-12-21 2021-09-08 ICM (Institut du Cerveau et de la Moelle Épinière) System und verfahren zur messung und überwachung von neurodegeneration
WO2020176533A1 (en) 2019-02-25 2020-09-03 Starkey Laboratories, Inc. Integration of sensor-based cardiovascular measures into physical benefit measure related to hearing instrument use
EP3706441B1 (de) 2019-03-07 2025-01-22 Oticon A/s Hörgerät mit einem sensorkonfigurationsdetektor
US11590313B2 (en) 2019-03-25 2023-02-28 Bose Corporation Smart relaxation mask
US10835145B1 (en) 2019-06-21 2020-11-17 Bose Corporation Ear tips capable of capturing bioelectrical signals and providing nerve stimulation
US20210241909A1 (en) * 2020-02-03 2021-08-05 Koninklijke Philips N.V. Method and a system for evaluating treatment strategies on a virtual model of a patient
US20210282706A1 (en) * 2020-03-16 2021-09-16 Koninklijke Philips N.V. Characterizing stimuli response to detect sleep disorders
US11911177B2 (en) * 2020-07-01 2024-02-27 Medtronic, Inc. Determining an efficacy of a treatment program
EP4401622A4 (de) * 2021-09-14 2025-07-09 Applied Cognition Inc Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190380648A1 (en) * 2017-02-21 2019-12-19 Bose Corporation Collecting biologically-relevant information using an earpiece
WO2020210813A1 (en) * 2019-04-11 2020-10-15 The General Hospital Corporation Generating imaging-based neurological state biomarkers and estimating cerebrospinal fluid (csf) dynamics based on coupled neural and csf oscillations during sleep

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2023043490A1 *

Also Published As

Publication number Publication date
US20230080140A1 (en) 2023-03-16
WO2023043490A1 (en) 2023-03-23
AU2022344928A1 (en) 2024-03-28
US20230389855A1 (en) 2023-12-07
US11759142B2 (en) 2023-09-19
US20240268748A1 (en) 2024-08-15
JP2024535131A (ja) 2024-09-26
US11478184B1 (en) 2022-10-25
EP4401622A1 (de) 2024-07-24

Similar Documents

Publication Publication Date Title
EP4401622A4 (de) Nichtinvasive beurteilung des glymphatischen flusses und der neurodegeneration aus einer wearable-vorrichtung
EP4282314A4 (de) Basis einer reinigungsvorrichtung und reinigungssystem
EP4120331A4 (de) Spannstruktur einer halbleiter-reinigungsvorrichtung und halbleiter-reinigungsvorrichtung
EP4098992C0 (de) Probenahmevorrichtung und verwendung einer probenahmevorrichtung
EP3993892C0 (de) Filtervorrichtung nebst filterelement
DE112017000592A5 (de) Filterelement eines Flüssigkeitsfilters und Flüssigkeitsfilter
EP3797749C0 (de) Wearable-vorrichtung und nicht-therapeutisches betriebsverfahren der wearable-vorrichtung
EP3828193C0 (de) Kristallform einer lanosterol-prodrug-verbindung und anwendung davon
DE112017002754A5 (de) Filterelement einer Filtervorrichtung, Filtergehäuse und Filtervorrichtung
EP4279984A4 (de) Wearable-vorrichtung und trageelement dafür
EP4246557A4 (de) Bildgebungselement und bildgebungsvorrichtung
EP3728063C0 (de) Gebinde aus packungsmänteln und einer umverpackung
EP4395359A4 (de) Bildgebungselement und bildgebungsvorrichtung
EP4159734C0 (de) Fluorpyrrolopyridinverbindung und anwendung davon
EP4104937A4 (de) Beschichtungsdüse und beschichtungsvorrichtung
EP3600013A4 (de) Physiologische überwachungsvorrichtungen und verfahren zur rauschverminderung bei physiologischen signalen auf der basis des personenaktivitätstyps
EP4428125A4 (de) Bicyclische verbindung und anwendung davon
EP4171278C0 (de) Nikotin-e-vaping-vorrichtung und komponenten davon
EP4036303A4 (de) Wassereinlassstruktur einer bekleidungsbehandlungsvorrichtung und bekleidungsbehandlungsvorrichtung
EP3960267A4 (de) Filterelement und filtervorrichtung
EP4043082C0 (de) Filtervorrichtung und filterelement
EP4453000A4 (de) Auristatin-analoga und immunokonjugate davon
EP3964482C0 (de) Kombination aus druckwassertank und wasserfilter
EP4134051C0 (de) Dampfanwendung und vorrichtungen zur dampfanwendung
EP4071584C0 (de) Online-autokalibrierung einer computer-gehirn-schnittstellenvorrichtung und computer-gehirn-schnittstellenvorrichtung

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20240312

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
P01 Opt-out of the competence of the unified patent court (upc) registered

Free format text: CASE NUMBER: APP_646/2025

Effective date: 20250107

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Free format text: PREVIOUS MAIN CLASS: A61B0005000000

Ipc: G16H0050200000

A4 Supplementary search report drawn up and despatched

Effective date: 20250610

RIC1 Information provided on ipc code assigned before grant

Ipc: G01R 33/563 20060101ALN20250603BHEP

Ipc: G01R 33/56 20060101ALN20250603BHEP

Ipc: A61B 6/03 20060101ALI20250603BHEP

Ipc: A61B 5/024 20060101ALI20250603BHEP

Ipc: A61B 5/02 20060101ALI20250603BHEP

Ipc: A61B 5/053 20210101ALI20250603BHEP

Ipc: A61B 5/369 20210101ALI20250603BHEP

Ipc: A61B 5/00 20060101ALI20250603BHEP

Ipc: G16H 40/63 20180101ALI20250603BHEP

Ipc: G16H 20/10 20180101ALI20250603BHEP

Ipc: G16H 50/30 20180101ALI20250603BHEP

Ipc: G16H 50/20 20180101AFI20250603BHEP