EP4346746A1 - Hydrogels including biopolymers - Google Patents
Hydrogels including biopolymersInfo
- Publication number
- EP4346746A1 EP4346746A1 EP22725516.3A EP22725516A EP4346746A1 EP 4346746 A1 EP4346746 A1 EP 4346746A1 EP 22725516 A EP22725516 A EP 22725516A EP 4346746 A1 EP4346746 A1 EP 4346746A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- weight
- hydrogel
- total
- proportion
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000017 hydrogel Substances 0.000 title claims abstract description 68
- 229920001222 biopolymer Polymers 0.000 title description 2
- 239000000230 xanthan gum Substances 0.000 claims abstract description 16
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 16
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 16
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 16
- 239000000679 carrageenan Substances 0.000 claims abstract description 15
- 235000010418 carrageenan Nutrition 0.000 claims abstract description 15
- 229920001525 carrageenan Polymers 0.000 claims abstract description 15
- 229940113118 carrageenan Drugs 0.000 claims abstract description 15
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims abstract description 15
- 239000002537 cosmetic Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- 229920000642 polymer Polymers 0.000 claims description 10
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 6
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 6
- 229920005862 polyol Polymers 0.000 claims description 6
- 150000003077 polyols Chemical class 0.000 claims description 6
- 125000004432 carbon atom Chemical group C* 0.000 claims description 5
- QWGRWMMWNDWRQN-UHFFFAOYSA-N 2-methylpropane-1,3-diol Chemical compound OCC(C)CO QWGRWMMWNDWRQN-UHFFFAOYSA-N 0.000 claims description 4
- 238000007334 copolymerization reaction Methods 0.000 claims description 4
- 229940100573 methylpropanediol Drugs 0.000 claims description 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 2
- 229940043375 1,5-pentanediol Drugs 0.000 claims description 2
- 229960005150 glycerol Drugs 0.000 claims description 2
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 claims description 2
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 2
- 229960004063 propylene glycol Drugs 0.000 claims description 2
- 230000006641 stabilisation Effects 0.000 abstract 1
- 238000011105 stabilization Methods 0.000 abstract 1
- 239000000499 gel Substances 0.000 description 12
- 239000000126 substance Substances 0.000 description 10
- 239000002270 dispersing agent Substances 0.000 description 8
- 239000002562 thickening agent Substances 0.000 description 7
- 239000000203 mixture Substances 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 4
- 239000003349 gelling agent Substances 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000008406 cosmetic ingredient Substances 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 230000009881 electrostatic interaction Effects 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229960005323 phenoxyethanol Drugs 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 244000007835 Cyamopsis tetragonoloba Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 239000001828 Gelatine Substances 0.000 description 1
- 241000218378 Magnolia Species 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 1
- 229960002079 calcium pantothenate Drugs 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 229940115458 pantolactone Drugs 0.000 description 1
- SIEVQTNTRMBCHO-UHFFFAOYSA-N pantolactone Natural products CC1(C)OC(=O)CC1O SIEVQTNTRMBCHO-UHFFFAOYSA-N 0.000 description 1
- SERHXTVXHNVDKA-UHFFFAOYSA-N pantolactone Chemical compound CC1(C)COC(=O)C1O SERHXTVXHNVDKA-UHFFFAOYSA-N 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000006254 rheological additive Substances 0.000 description 1
- 150000003839 salts Chemical group 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- YRWWOAFMPXPHEJ-OFBPEYICSA-K sodium L-ascorbic acid 2-phosphate Chemical compound [Na+].[Na+].[Na+].OC[C@H](O)[C@H]1OC(=O)C(OP([O-])([O-])=O)=C1[O-] YRWWOAFMPXPHEJ-OFBPEYICSA-K 0.000 description 1
- 229940048058 sodium ascorbyl phosphate Drugs 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/594—Mixtures of polymers
Definitions
- cosmetic products not only serve to look beautiful and attractive, but with their effect they make a decisive contribution to increased self-esteem and the well-being of people. Accordingly, a wide variety of cosmetic products are used for the daily cleaning and care of human skin.
- the present invention relates to a water-containing, transparent gel (hydrogel) which, in addition to water, comprises at least two gel formers.
- the gel according to the invention preferably contains at least one cosmetic active ingredient.
- Hydrogels and their use for administering cosmetic ingredients to the skin or mucosa of a human are known.
- the term "gel” is understood to mean relatively dimensionally stable, easily deformable disperse systems made up of at least two components, which usually consist of a - usually solid - colloidally divided substance made up of long-chain molecular groups (e.g. gelatine, silicic acid, polysaccharides) as a builder and a liquid dispersing agent (e.g. water.
- the colloidally divided substance is often referred to as a thickening agent, gelling agent or gelling agent. It forms a spatial network in the dispersing agent, with individual colloidally present particles more or less firmly connected to one another via electrostatic interaction can be linked.
- Acrylic acid polymers are mainly used as thickeners.
- the existing free carboxy groups of these polymers are by alkalis - such.
- cellulose derivatives or other polysaccharides, such as guar flour or xanthan gum are used as gelling agents. Depending on the type and amount of thickening agent, the consistency of a gel can be adjusted from liquid to firm.
- the dispersing agent surrounding the network is characterized by electrostatic affinity for the thickening agent, ie a predominantly polar (especially: hydrophilic) thickening agent preferably gels a polar dispersing agent (particularly: water), whereas a predominantly non-polar thickener preferentially gels non-polar dispersing agents.
- Hydrogels can consist of almost 100% water (in addition to, for example, approx. 0.2-1.0% of a gelling agent) and can have a solid consistency.
- gels are generally characterized by a semi-solid, often flowable consistency.
- hydrogels from DE2005056497 A1, among others.
- acrylate-based polymers are often used for gel formation.
- Acrylate-based polymers are polymers obtained from homo- or copolymerization with acrylic and/or methacrylic acid. Examples include sodium polyacrylate or acrylate copolymer.
- the subject matter of the present invention is a cosmetic hydrogel comprising a) dehydroxanthan gum and b) xanthan gum and/or carrageenan and c) water.
- Another object of the invention is the use of xanthan gum and/or carrageenan for stabilizing the viscosity of a hydrogel comprising dehydroxanthan gum and water.
- weight percentage ranges are given below for the components of the hydrogel, the disclosure of the present application also includes all individual values in increments of 0.1% by weight within these weight percentage ranges.
- formulations “according to the invention”, “advantageous according to the invention”, “advantageous in the sense of the present invention” etc. always refer both to the hydrogel according to the invention and to the use according to the invention.
- normal conditions means 20°C, 1013 hPa and a relative humidity of 50%.
- skin it preferably refers to human skin.
- Emulsifiers are understood to mean all substances that are listed in the International Cosmetic Ingredient Dictionary and Handbook, Thirteenth Edition 2010, (ISBN 1-882621-47-6) under the designation "emulsifying agent".
- Surfactants are understood to be all substances that are listed under the name “surfactant” in the International Cosmetic Ingredient Dictionary and Handbook, Thirteenth Edition 2010, (ISBN 1-882621-47-6).
- viscosity values relate to a measurement at 25° C. in a 150 ml wide-mouth bottle (VWR No.: 807-001) using Rheomat R 123 from the company proRheo.
- the Rheomat R 123 from proRheo GmbH is a Rotational viscometer, ie a measuring body rotates in the substance to be measured. The force required to rotate the measuring body in the sample at a specified speed is measured. The viscosity is calculated from this torque, the speed of the measuring body and the geometric dimensions of the measuring system used.
- Measuring body No. 1 (Article No. 200 0191), suitable for a viscosity range up to 10,000 [mPa-s], speed range 62.5 min-1, is used as the measuring body.
- the cosmetic hydrogel comprises dehydroxanthan gum. It is advantageous for the purposes of the present invention if the proportion of dehydroxanthan gum is from 0.1% by weight to 5% by weight, preferably from 0.3% by weight to 3.5% by weight and is particularly preferred from 0.6% to 2% by weight based on the total weight of the hydrogel.
- xanthan gum and/or carrageenan are contained.
- the total proportion of xanthan gum and/or carrageenan is advantageously from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0.7% by weight % by weight based on the total weight of the hydrogel.
- the proportion of xanthan gum is advantageously from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0 .7% by weight based on the total weight of the hydrogel.
- the proportion of carrageenan is advantageously from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0.7% by weight % by weight based on the total weight of the hydrogel.
- the weight ratio of dehydroxanthan gum to the total amount of xanthan gum and/or carrageenan is advantageously from 10:1 to 1:1, preferably from 8:1 to 1.5:1 and particularly preferably 5:1 to 2:1.
- the total proportion of water is advantageously at least 70% by weight, preferably at least 75% by weight and particularly preferably at least 77% by weight, based on the total weight of the hydrogel.
- the total proportion of water is advantageously less than 99% by weight, based on the total weight of the hydrogel.
- the hydrogel according to the invention is preferably free from polymers which are obtained from a homopolymerization or copolymerization with vinylpyrrolidone, acrylic and/or methacrylic acid.
- free means that the total proportion of the substances mentioned is less than 0.05% by weight and particularly preferably 0% by weight, the details relating to the total weight of the hydrogel.
- hydrogel is free from emulsifiers and surfactants.
- the hydrogel comprises other ingredients which are customarily used in such formulations.
- the hydrogel contains one or more short-chain polyols having 2 to 8 carbon atoms.
- the proportion of these polyols having 2 to 8 carbon atoms is advantageously from 1 to 30% by weight, preferably from 2 to 23% by weight and particularly preferably from 3 to 20% by weight, based on the total weight of the hydrogel.
- Preferred polyols having 2 to 8 carbon atoms are selected from the group consisting of glycerol, methylpropanediol, propylene glycol, 1,2-hexanediol, caprylyl glycol, butylene glycol and pentylene glycol.
- the hydrogel contains glycerol, it is preferred if the proportion of glycerol is from 5 to 15% by weight, preferably from 7 to 12.5% by weight and particularly preferably from 8 to 12% by weight, based on the total weight of the hydrogel .
- the hydrogel contains methylpropanediol, it is preferred if the proportion of methylpropanediol is from 1 to 10% by weight, preferably from 2 to 8% by weight and particularly preferably from 3 to 5% by weight, based on the total weight of the hydrogel.
- the hydrogel contains propylene glycol, it is preferred if the proportion of propylene glycol is from 1 to 10% by weight, preferably from 2 to 8% by weight and particularly preferably from 3 to 5% by weight, based on the total weight of the hydrogel .
- the hydrogel contains 1,2-hexanediol, it is preferred if the proportion of 1,2-hexanediol is from 0.2 to 2% by weight, preferably from 0.5 to 1.5 and particularly preferably from 0.7 to 1.3% by weight based on the total weight of the hydrogel. It is also advantageous if the hydrogel contains phenoxyethanol, it being advantageous if the proportion of phenoxyethanol is from 0.2 to 1.5% by weight, preferably from 0.4 to 1.0% by weight and particularly preferred from 0.5 to 0.9% by weight based on the total weight of the hydrogel.
- active ingredients are present. These are advantageously selected from the group containing sodium hyaluronate, 1-methylhydantoin-2-imide, creatine, folic acid, panthenol, pantolactone, vitamin C, magnolia, calcium pantothenate and sodium ascorbyl phosphate.
- the active ingredients mentioned in the group are advantageously used in total proportions of up to 2% by weight, based on the total weight of the hydrogel.
- cosmetic auxiliaries such as other active ingredients, dyes, rheology modifiers, alcohols, oils and waxes can also be present, provided they do not adversely affect the properties according to the invention.
- the gels of the invention are characterized in that they are transparent. This property is often appreciated by consumers.
- a gel can be regarded as transparent if it shows a transmission of 85% at 500 nm under normal conditions.
- a comparison shows that when stored for up to 120 days, the increase in viscosity could be reduced by adding carrageenan or xanthan gum. In this way, hydrogels with a higher viscosity could be provided.
- the hydrogels according to the invention appear transparent.
Abstract
The present invention relates to a cosmetic hydrogel containing dehydroxanthan gum and xanthan gum and/or carrageenan, and to the use of xanthan gum and/or carrageenan for viscosity stabilization of a hydrogel comprising dehydroxanthan gum.
Description
Hvdroqele mit Biopolvmeren Hydroqele with biopolymers
Kosmetische Produkte dienen im Allgemeinen nicht nur dazu schön und attraktiv auszusehen, sondern sie tragen mit ihrer Wirkung entscheidend zu einem gesteigerten Selbstwertgefühl und zum Wohlbefinden der Menschen bei. Dementsprechend werden die verschiedensten kosmetischen Produkte zur täglichen Reinigung und Pflege der menschlichen Haut eingesetzt. In general, cosmetic products not only serve to look beautiful and attractive, but with their effect they make a decisive contribution to increased self-esteem and the well-being of people. Accordingly, a wide variety of cosmetic products are used for the daily cleaning and care of human skin.
Die vorliegende Erfindung betrifft ein wasserhaltiges transparents Gel (Hydrogel), das neben Wasser, mindestens zwei Gelbildner umfasst. Bevorzugt enthält das erfindungsgemäße Gel mindestens einen kosmetischen Wirkstoff. The present invention relates to a water-containing, transparent gel (hydrogel) which, in addition to water, comprises at least two gel formers. The gel according to the invention preferably contains at least one cosmetic active ingredient.
Hydrogele und deren Verwendung zur Verabreichung von kosmetischen Inhaltsstoffen an die Haut oder Schleimhaut eines Menschen sind bekannt. Im technischen Sinn werden unter dem Begriff „Gel" relativ formbeständige, leicht verformbare disperse Systeme aus zumindest zwei Komponenten verstanden, welche in der Regel aus einem - meist festen - kolloid zerteilten Stoff aus langkettigen Molekülgruppierungen (z. B. Gelatine, Kieselsäure, Polysaccharide) als Gerüstbildner und einem flüssigen Dispersionsmittel (z. B. Wasser) bestehen. Der kolloidal zerteilte Stoff wird oft als Verdickungsmittel, Gelbildner oder Geliermittel bezeichnet. Er bildet ein räumliches Netzwerk im Dispersionsmittel, wobei einzelne kolloidal vorliegende Partikel über elektrostatische Wechselwirkung miteinander mehr oder weniger fest verknüpft sein können. Hydrogels and their use for administering cosmetic ingredients to the skin or mucosa of a human are known. In the technical sense, the term "gel" is understood to mean relatively dimensionally stable, easily deformable disperse systems made up of at least two components, which usually consist of a - usually solid - colloidally divided substance made up of long-chain molecular groups (e.g. gelatine, silicic acid, polysaccharides) as a builder and a liquid dispersing agent (e.g. water. The colloidally divided substance is often referred to as a thickening agent, gelling agent or gelling agent. It forms a spatial network in the dispersing agent, with individual colloidally present particles more or less firmly connected to one another via electrostatic interaction can be linked.
Als Verdickungsmittel werden hauptsächlich Acrylsäure-Polymere verwendet. Die vorhandenen freien Carboxy-Gruppen dieser Polymere werden durch Alkalien - wie z. B. Natronlauge oder Amine - in die Salzform überführt und führen dadurch infolge einer starken Vernetzung zu einer Viskositätserhöhung. Weiterhin kommen auch Cellulose-Derivate oder andere Polysaccharide, wie zum Beispiel Guar-Mehl oder Xanthan, als Gelbildner zum Einsatz. Je nach Art und Menge des Verdickungsmittels lässt sich die Konsistenz eines Geles von flüssig bis schnittfest einstellen. Acrylic acid polymers are mainly used as thickeners. The existing free carboxy groups of these polymers are by alkalis - such. B. caustic soda or amines - converted into the salt form and thus lead to an increase in viscosity as a result of strong crosslinking. Furthermore, cellulose derivatives or other polysaccharides, such as guar flour or xanthan gum, are used as gelling agents. Depending on the type and amount of thickening agent, the consistency of a gel can be adjusted from liquid to firm.
Das Dispersionsmittel, welches das Netzwerk umgibt, zeichnet sich durch elektrostatische Affinität zum Verdickungsmittel aus, d. h., ein vorwiegend polares (insbesondere: hydrophiles) Verdickungsmittel geliert vorzugsweise ein polares Dispersionsmittel
(insbesondere: Wasser), wohingegen ein vorwiegend unpolares Verdickungsmittel vorzugsweise unpolare Dispersionsmittel geliert. The dispersing agent surrounding the network is characterized by electrostatic affinity for the thickening agent, ie a predominantly polar (especially: hydrophilic) thickening agent preferably gels a polar dispersing agent (particularly: water), whereas a predominantly non-polar thickener preferentially gels non-polar dispersing agents.
Starke elektrostatische Wechselwirkungen, welche beispielsweise in Wasserstoffbrückenbindungen zwischen Verdickungsmittel und Dispersionsmittel, aber auch zwischen Dispersionsmittelmolekülen untereinander verwirklicht sind, können zu starker Vernetzung auch des Dispersionsmittels führen. Hydrogele können zu fast 100 % aus Wasser bestehen (neben beispielsweise ca. 0, 2-1,0 % eines Geliermittels) und dabei durchaus feste Konsistenz besitzen. Strong electrostatic interactions, which are realized, for example, in hydrogen bridge bonds between thickener and dispersant, but also between dispersant molecules with one another, can also lead to strong crosslinking of the dispersant. Hydrogels can consist of almost 100% water (in addition to, for example, approx. 0.2-1.0% of a gelling agent) and can have a solid consistency.
In der kosmetischen Galenik zeichnen sich Gele in aller Regel durch eine halbfeste, oft fließfähige Konsistenz aus. In cosmetic galenics, gels are generally characterized by a semi-solid, often flowable consistency.
Der Fachmann kennt Hydrogele u.a. aus DE2005056497 A1. The person skilled in the art knows hydrogels from DE2005056497 A1, among others.
Im Stand der Technik ist bekannt, dass oftmals zur Gelbildung Acrylat-basiete Polymere eingesetzt werden. Acrylat-basierte Polymere sind Polymere, welche aus Homo- oder Copolymerisation mit Acryl- und/oder Methacrylsäure erhalten werden. Beispiele hierfür sind u.a. Natriumpolyacrylate oder Acrylate Copolymer. Alternativ zu Acrylat-basieten Polymeren ist es ebenfalls möglich Polymere, welche aus Homo- oder Copolymerisation mit Vinylpyrrolidon gebildet werden, zur Gelbildung einzusetzen. It is known in the prior art that acrylate-based polymers are often used for gel formation. Acrylate-based polymers are polymers obtained from homo- or copolymerization with acrylic and/or methacrylic acid. Examples include sodium polyacrylate or acrylate copolymer. As an alternative to acrylate-based polymers, it is also possible to use polymers formed from homo- or copolymerization with vinylpyrrolidone for gel formation.
Nachteilig ist jedoch der Umstand, dass der Einsatz dieser genannten Polymere zunehmend in der Kritik, da deren biologische Abbaubarkeit nicht vollständig geklärt ist. Folglich besteht ein Bedarf an Hydrogelen, welche nicht auf den Einsatz dieser Polymere basiert. A disadvantage, however, is the fact that the use of these polymers mentioned is increasingly being criticized since their biodegradability has not been fully clarified. Consequently, there is a need for hydrogels that are not based on the use of these polymers.
Bei der Bereitstellung transparenter Hydrogele treten jedoch unvorhergesehene Probleme auf. So erhöht sich oftmals die Viskosität der Hydrogele bei Lagerung kontinuierlich, so dass abhängig von der Lagerdauer sich die Eigenschaften der Hydrogele verändern. However, unforeseen problems arise in providing transparent hydrogels. The viscosity of the hydrogels often increases continuously during storage, so that the properties of the hydrogels change depending on the storage period.
Überraschend wurde nun gefunden, dass die Nachteile des Standes der Technik durch die vorliegende Erfindung beseitigt bzw. gelindert werden konnten. Surprisingly, it has now been found that the disadvantages of the prior art can be eliminated or alleviated by the present invention.
Gegenstand der vorliegenden Erfindung ist ein kosmetisches Hydrogel aufweisend a) Dehydroxanthan Gum und b) Xanthan Gum und/oder Carrageenan und c) Wasser.
Ein weiterer Gegenstand der Erfindung ist die Verwendung von Xanthan Gum und/oder Carrageenan zur Viskositätsstabilisierung eines Hydrogels aufweisend Dehydroxanthan Gum und Wasser. The subject matter of the present invention is a cosmetic hydrogel comprising a) dehydroxanthan gum and b) xanthan gum and/or carrageenan and c) water. Another object of the invention is the use of xanthan gum and/or carrageenan for stabilizing the viscosity of a hydrogel comprising dehydroxanthan gum and water.
Sollten nachfolgend Gewichtsprozentangaben (Gew.-%) ohne Bezugnahme auf eine bestimmte Zusammensetzung oder spezifische Mischung angegeben werden, so beziehen sich diese Angaben immer auf das Gesamtgewicht Hydrogels. Sollten nachfolgend Verhältnisse von Komponenten/Substanzen/Stoffgruppen offenbart werden, so beziehen sich diese Verhältnisse auf Gewichtsverhältnisse der genannten Komponenten/If weight percentages (% by weight) are given below without reference to a specific composition or specific mixture, these details always relate to the total weight of the hydrogel. If ratios of components/substances/groups of substances are disclosed below, these ratios relate to weight ratios of the components/
Substanze n/Stoffg ru p pe n . Substances/groups of substances.
Werden nachfolgend Gewichtsprozentbereiche für die Bestandteile des Hydrogels angegeben, so umfasst die Offenbarung der vorliegenden Anmeldung ebenfalls alle Einzelwerte in Schritten von 0,1 Gew.-% innerhalb dieser Gewichtsprozentbereiche. If weight percentage ranges are given below for the components of the hydrogel, the disclosure of the present application also includes all individual values in increments of 0.1% by weight within these weight percentage ranges.
Die Formulierungen „erfindungsgemäß“, „erfindungsgemäß vorteilhaft“, „vorteilhaft im Sinne der vorliegenden Erfindung“ etc. beziehen sich im Rahmen der vorliegenden Offenbarung immer sowohl auf das erfindungsgemäße Hydrogel sowie die erfindungsgemäße Verwendung. In the context of the present disclosure, the formulations “according to the invention”, “advantageous according to the invention”, “advantageous in the sense of the present invention” etc. always refer both to the hydrogel according to the invention and to the use according to the invention.
Sofern nicht anders angegeben wurden alle Versuche unter Normalbedingungen durchgeführt. Der Begriff „Normalbedingungen“ bedeutet 20°C, 1013 hPa und eine relative Luftfeuchtigkeit von 50%. Unless otherwise stated, all tests were carried out under standard conditions. The term "normal conditions" means 20°C, 1013 hPa and a relative humidity of 50%.
Wird der Begriff Haut verwendet, so bezieht dieser sich bevorzugt auf die menschliche Haut. If the term skin is used, it preferably refers to human skin.
Unter Emulgatoren werden alle Substanzen verstanden, welche im International Cosmetic Ingredient Dictionary and Handbook, Thirteenth Edition 2010, (ISBN 1-882621-47-6) unter der Bezeichnung “emulsifying agent” geführt werden. Unter Tensiden werden alle Substanzen verstanden, welche im International Cosmetic Ingredient Dictionary and Handbook, Thirteenth Edition 2010, (ISBN 1-882621-47-6) unter der Bezeichnung “ Surfactant ” geführt werden. Emulsifiers are understood to mean all substances that are listed in the International Cosmetic Ingredient Dictionary and Handbook, Thirteenth Edition 2010, (ISBN 1-882621-47-6) under the designation "emulsifying agent". Surfactants are understood to be all substances that are listed under the name “surfactant” in the International Cosmetic Ingredient Dictionary and Handbook, Thirteenth Edition 2010, (ISBN 1-882621-47-6).
Werden in dieser Offenbarung Viskositätswerte angegeben, so beziehen sich alle Werte auf eine Messung bei 25°C in einer 150 ml Weithalsflasche (VWR Nr.: 807-001) mittels Rheomat R 123 von der Firma proRheo. Der Rheomat R 123 der Firma proRheo GmbH ist ein
Rotationsviskosimeter, d. h. ein Messkörper rotiert in der zu vermessenden Substanz. Es wird die Kraft gemessen, die benötigt wird, um den Messkörper in der Probe mit einer vorgegebenen Drehzahl rotieren zu lassen. Aus diesem Drehmoment, der Drehzahl des Messkörpers und den geometrischen Abmessungen des verwendeten Messsystems wird die Viskosität berechnet. Als Messkörper wird der Messkörper Nr.1 (Artikelnr. 200 0191), geeignet für einen Viskositätsbereich bis 10.000 [mPa-s], Drehzahl Bereich 62,5 min-1, verwendet. If viscosity values are given in this disclosure, then all values relate to a measurement at 25° C. in a 150 ml wide-mouth bottle (VWR No.: 807-001) using Rheomat R 123 from the company proRheo. The Rheomat R 123 from proRheo GmbH is a Rotational viscometer, ie a measuring body rotates in the substance to be measured. The force required to rotate the measuring body in the sample at a specified speed is measured. The viscosity is calculated from this torque, the speed of the measuring body and the geometric dimensions of the measuring system used. Measuring body No. 1 (Article No. 200 0191), suitable for a viscosity range up to 10,000 [mPa-s], speed range 62.5 min-1, is used as the measuring body.
Erfindungsgemäß umfasst das kosmetische Hydrogel Dehydroxanthan Gum. Es ist vorteilhaft im Sinne der vorliegenden Erfindung, wenn der Anteil von Dehydroxanthan Gum von 0,1 Gew.-% bis 5 Gew.-%, bevorzugt von 0,3 Gew.-% bis 3,5 Gew.-% und insbesondere bevorzugt von 0,6 Gew.-% bis 2 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels beträgt. According to the invention, the cosmetic hydrogel comprises dehydroxanthan gum. It is advantageous for the purposes of the present invention if the proportion of dehydroxanthan gum is from 0.1% by weight to 5% by weight, preferably from 0.3% by weight to 3.5% by weight and is particularly preferred from 0.6% to 2% by weight based on the total weight of the hydrogel.
Weiterhin ist es erfindungsgemäß, dass Xanthan Gum und/oder Carrageenan enthalten sind. Vorteilhaft beträgt der Gesamtanteil von Xanthan Gum und/oder Carrageenan von 0,1 bis 3 Gew.-%, bevorzugt von 0,15 Gew.-% bis 1,5 Gew.-% und insbesondere bevorzugt von 0,2 bis 0,7 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels. Furthermore, it is according to the invention that xanthan gum and/or carrageenan are contained. The total proportion of xanthan gum and/or carrageenan is advantageously from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0.7% by weight % by weight based on the total weight of the hydrogel.
Sofern Xanthan Gum enthalten ist, beträgt der Anteil von Xanthan Gum vorteilhaft von 0,1 bis 3 Gew.-%, bevorzugt von 0,15 Gew.-% bis 1,5 Gew.-% und insbesondere bevorzugt von 0,2 bis 0,7 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels. If xanthan gum is included, the proportion of xanthan gum is advantageously from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0 .7% by weight based on the total weight of the hydrogel.
Sofern Carrageenan enthalten ist, beträgt der Anteil von Carrageenan vorteilhaft von 0,1 bis 3 Gew.-%, bevorzugt von 0,15 Gew.-% bis 1,5 Gew.-% und insbesondere bevorzugt von 0,2 bis 0,7 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels. If carrageenan is present, the proportion of carrageenan is advantageously from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0.7% by weight % by weight based on the total weight of the hydrogel.
Vorteilhaft beträgt das Gewichtsverhältnis von Dehydroxanthan Gum zum Gesamtanteil von Xanthan Gum und/oder Carrageenan von 10:1 bis 1:1, bevorzugt von 8:1 bis 1,5:1 und insbesondere bevorzugt 5:1 bis 2:1. The weight ratio of dehydroxanthan gum to the total amount of xanthan gum and/or carrageenan is advantageously from 10:1 to 1:1, preferably from 8:1 to 1.5:1 and particularly preferably 5:1 to 2:1.
Der Gesamtanteil von Wasser beträgt vorteilhaft mindestens 70 Gew.-%, bevorzugt mindestens 75 Gew.-% und insbesondere bevorzugt mindestens 77 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels. Der Gesamtanteil von Wasser beträgt vorteilhaft weniger als 99 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels.
Das erfindungsgemäße Hydrogel ist bevorzugt frei von Polymeren, welche aus einer Homo oder Copolymerisation mit Vinylpyrrolidon, Acryl- und/oder Methacrylsäure erhalten werden. Frei von Sinne der vorliegenden Erfindung bedeutet, dass der Gesamtanteil der genannten Substanzen weniger als 0,05 Gew.-% und insbesondere bevorzugt 0 Gew-% beträgt, wobei sich die Angaben auf das Gesamtgewicht des Hydrogels beziehen. The total proportion of water is advantageously at least 70% by weight, preferably at least 75% by weight and particularly preferably at least 77% by weight, based on the total weight of the hydrogel. The total proportion of water is advantageously less than 99% by weight, based on the total weight of the hydrogel. The hydrogel according to the invention is preferably free from polymers which are obtained from a homopolymerization or copolymerization with vinylpyrrolidone, acrylic and/or methacrylic acid. For the purposes of the present invention, free means that the total proportion of the substances mentioned is less than 0.05% by weight and particularly preferably 0% by weight, the details relating to the total weight of the hydrogel.
Ferner ist es vorteilhaft, wenn das Hydrogel frei ist von Emulgatoren und Tensiden. It is also advantageous if the hydrogel is free from emulsifiers and surfactants.
Weiterhin ist es erfindungsgemäß vorteilhaft, wenn das Hydrogel weitere Inhaltstoffe umfasst, welche üblicher weise in derartigen Formulierungen eingesetzt werden. Furthermore, it is advantageous according to the invention if the hydrogel comprises other ingredients which are customarily used in such formulations.
Entsprechend ist es vorteilhaft, wenn das Hydrogel ein oder mehrere kurzkettige Polyole aufweisend 2 bis 8 Kohlenstoffatome enthält. Vorteilhaft beträgt der Anteil dieser Polyole aufweisend 2 bis 8 Kohlenstoffatome von 1 bis 30 Gew.-%, bevorzugt von 2 bis 23 Gew.-% und insbesondere bevorzugt von 3 bis 20 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels. Accordingly, it is advantageous if the hydrogel contains one or more short-chain polyols having 2 to 8 carbon atoms. The proportion of these polyols having 2 to 8 carbon atoms is advantageously from 1 to 30% by weight, preferably from 2 to 23% by weight and particularly preferably from 3 to 20% by weight, based on the total weight of the hydrogel.
Bevorzugte Polyole aufweisend 2 bis 8 Kohlenstoffatome sind gewählt aus der Gruppe bestehend aus Glycerin, Methylpropanediol, Propylene Glycol, 1,2- Hexanediol, Caprylyl Glycol, Butylene Glycol und Pentylene Glycol. Preferred polyols having 2 to 8 carbon atoms are selected from the group consisting of glycerol, methylpropanediol, propylene glycol, 1,2-hexanediol, caprylyl glycol, butylene glycol and pentylene glycol.
Sofern das Hydrogel Glycerin enthält, ist es bevorzugt, wenn der Anteil von Glycerin von 5 bis 15 Gew.-%, bevorzugt von 7 bis 12,5 und insbesondere bevorzugt von 8 bis 12 Gew.-% beträgt, bezogen auf das Gesamtgewicht des Hydrogels. If the hydrogel contains glycerol, it is preferred if the proportion of glycerol is from 5 to 15% by weight, preferably from 7 to 12.5% by weight and particularly preferably from 8 to 12% by weight, based on the total weight of the hydrogel .
Sofern das Hydrogel Methylpropanediol enthält, ist es bevorzugt, wenn der Anteil von Methylpropanediol von 1 bis 10 Gew.-%, bevorzugt von 2 bis 8 und insbesondere bevorzugt von 3 bis 5 Gew.-% beträgt, bezogen auf das Gesamtgewicht des Hydrogels. If the hydrogel contains methylpropanediol, it is preferred if the proportion of methylpropanediol is from 1 to 10% by weight, preferably from 2 to 8% by weight and particularly preferably from 3 to 5% by weight, based on the total weight of the hydrogel.
Sofern das Hydrogel Propylene Glycol enthält, ist es bevorzugt, wenn der Anteil von Propylene Glycol von 1 bis 10 Gew.-%, bevorzugt von 2 bis 8 und insbesondere bevorzugt von 3 bis 5 Gew.-% beträgt, bezogen auf das Gesamtgewicht des Hydrogels. If the hydrogel contains propylene glycol, it is preferred if the proportion of propylene glycol is from 1 to 10% by weight, preferably from 2 to 8% by weight and particularly preferably from 3 to 5% by weight, based on the total weight of the hydrogel .
Sofern das Hydrogel 1,2- Hexanediol enthält, ist es bevorzugt, wenn der Anteil von 1,2- Hexanediol von 0,2 bis 2 Gew.-%, bevorzugt von 0,5 bis 1,5 und insbesondere bevorzugt von 0,7 bis 1,3 Gew.-% beträgt, bezogen auf das Gesamtgewicht des Hydrogels.
Ebenso ist es vorteilhaft, wenn das Hydrogel Phenoxyethanol enthält, wobei es vorteilhaft ist, wenn der Anteil von Phenoxyethanol von 0,2 bis 1,5 Gew.-%, bevorzugt von 0,4 bis 1,0 Gew.-% und insbesondere bevorzugt von 0,5 bis 0,9 Gew-%, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. If the hydrogel contains 1,2-hexanediol, it is preferred if the proportion of 1,2-hexanediol is from 0.2 to 2% by weight, preferably from 0.5 to 1.5 and particularly preferably from 0.7 to 1.3% by weight based on the total weight of the hydrogel. It is also advantageous if the hydrogel contains phenoxyethanol, it being advantageous if the proportion of phenoxyethanol is from 0.2 to 1.5% by weight, preferably from 0.4 to 1.0% by weight and particularly preferred from 0.5 to 0.9% by weight based on the total weight of the hydrogel.
Weiterhin ist es erfindungsgemäß vorteilhaft, wenn weitere Wirkstoffe enthalten sind. Diese sind vorteilhaft gewählt aus der Gruppe Sodium Hyaluronate, 1-Methylhydantoin-2-imide, Creatine, Folie Acid, Pantthenol, Pantolactone, Vitamin C, Magnolia, Calcium Pantothenate und Sodium Ascorbyl Phosphate enthält. Vorteilhaft werden die in der Gruppe genannten Wirkstoffen in Gesamtanteilen von bis zu 2 Gew.-% eingesetzt, bezogen auf das Gesamtgewicht des Hydrogels. Furthermore, it is advantageous according to the invention if other active ingredients are present. These are advantageously selected from the group containing sodium hyaluronate, 1-methylhydantoin-2-imide, creatine, folic acid, panthenol, pantolactone, vitamin C, magnolia, calcium pantothenate and sodium ascorbyl phosphate. The active ingredients mentioned in the group are advantageously used in total proportions of up to 2% by weight, based on the total weight of the hydrogel.
Ferner können weitere kosmetische Hilfsstoffe, wie weitere Wirkstoffe, Farbstoffe, Rheologiemodifizierer, Alkohole, Öle und Wachse enthalten sein, sofern sie die erfindungsgemäßen Eigenschaften nicht nachteilig beeinflussen. Other cosmetic auxiliaries such as other active ingredients, dyes, rheology modifiers, alcohols, oils and waxes can also be present, provided they do not adversely affect the properties according to the invention.
Vorteilhaft sind die Gele der Erfindung dadurch gekennzeichnet, dass diese transparent sind. Diese Eigenschaft wird oftmals von Verbrauchern geschätzt. Ein Gel ist als Transparent anzusehen, sofern es unter Normalbedingungen eine Transmission bei 500 nm von 85% zeigt. Advantageously, the gels of the invention are characterized in that they are transparent. This property is often appreciated by consumers. A gel can be regarded as transparent if it shows a transmission of 85% at 500 nm under normal conditions.
Vergleichsversuche und Beispiele Comparative tests and examples
Die nachfolgenden Beispiele sollen die vorliegende Erfindung verdeutlichen, ohne sie einzu schränken. Alle Mengenangaben, Anteile und Prozentanteile sind, soweit nicht anders an gegeben, auf das Gewicht und die Gesamtmenge bzw. auf das Gesamtgewicht der Zube reitungen bezogen. The following examples are intended to illustrate the present invention without restricting it. Unless otherwise stated, all amounts, parts and percentages are based on the weight and the total amount or the total weight of the preparations.
Nachfolgende Tabellen zeigen verschiedene Zusammensetzungen von Hydrogelen, sowie die gemessene Viskosität nach verschieden langer Lagerung unter Normalbedingungen. Die Messung der Viskosität erfolgte wie in der obigen Beschreibung angegeben. Bsp.1 bis Bsp.4 sind Vergleichsbeispiele. Bsp. 5 bis Bsp.8 sind erfindungsgemäß.
The tables below show various compositions of hydrogels and the viscosity measured after different lengths of storage under standard conditions. The viscosity was measured as indicated in the description above. Ex.1 to Ex.4 are comparative examples. Ex. 5 to Ex. 8 are according to the invention.
Ein Vergleich ergibt, dass bei Lagerung bis zu 120d die Viskositätssteigerung durch Zusatz von Carrageenan bzw. Xanthan Gum verringert werden konnte. So konnten viskositäts stabilere Hydrogele bereitgestellt werden. Die erfindungsgemäßen Hydrogele erscheinen transparent. A comparison shows that when stored for up to 120 days, the increase in viscosity could be reduced by adding carrageenan or xanthan gum. In this way, hydrogels with a higher viscosity could be provided. The hydrogels according to the invention appear transparent.
Weitere erfindungsgemäße Beispiele sind nachfolgend dargestellt: Tab.1
Further examples according to the invention are shown below: Tab.1
Tab.2
Tab.2
Tab.3
Tab.3
Tab.4
Tab.4
Tab.5
Tab.5
Tab.6
Tab.6
Claims
1. Kosmetisches Hydrogel aufweisend a. Dehydroxanthan Gum und b. Xanthan Gum und/oder Carrageenan und c. Wasser. 1. Cosmetic hydrogel comprising a. dehydroxanthan gum and b. xanthan gum and/or carrageenan and c. Water.
2. Verwendung von Xanthan Gum und/oder Carrageenan zur Viskositätsstabilisierung eines Hydrogels aufweisend Dehydroxanthan Gum und Wasser. 2. Use of xanthan gum and/or carrageenan to stabilize the viscosity of a hydrogel comprising dehydroxanthan gum and water.
3. Hydrogel nach Anspruch 1 oder Verwendung nach Anspruch 2 dadurch gekennzeichnet, dass der Anteil von Dehydroxanthan Gum von 0,1 Gew.-% bis 5 Gew.-%, bevorzugt von 0,3 Gew.-% bis 3,5 Gew.-% und insbesondere bevorzugt von 0,6 Gew.-% bis 2 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels beträgt. 3. Hydrogel according to claim 1 or use according to claim 2, characterized in that the proportion of dehydroxanthan gum is from 0.1% by weight to 5% by weight, preferably from 0.3% by weight to 3.5% by weight. -% and more preferably from 0.6% to 2% by weight, based on the total weight of the hydrogel.
4. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass der Gesamtanteil von Xanthan Gum und/oder Carrageenan von 0,1 bis 3 Gew.-%, bevorzugt von 0,15 Gew.-% bis 1,5 Gew.-% und insbesondere bevorzugt von 0,2 bis 0,7 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. 4. Hydrogel or use according to one of the preceding claims, characterized in that the total proportion of xanthan gum and/or carrageenan is from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight. % and most preferably from 0.2 to 0.7% by weight based on the total weight of the hydrogel.
5. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass der Anteil von Xanthan Gum von 0,1 bis 3 Gew.-%, bevorzugt von 0,15 Gew.-% bis 1,5 Gew.-% und insbesondere bevorzugt von 0,2 bis 0,7 Gew.- %, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. 5. Hydrogel or use according to one of the preceding claims, characterized in that the proportion of xanthan gum is from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferred from 0.2 to 0.7% by weight based on the total weight of the hydrogel.
6. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass der Anteil von Carrageenan von 0,1 bis 3 Gew.-%, bevorzugt von 0,15 Gew.-% bis 1,5 Gew.-% und insbesondere bevorzugt von 0,2 bis 0,7 Gew.- %, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. 6. Hydrogel or use according to any one of the preceding claims, characterized in that the proportion of carrageenan is from 0.1 to 3% by weight, preferably from 0.15% by weight to 1.5% by weight and particularly preferably from 0.2 to 0.7% by weight based on the total weight of the hydrogel.
7. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass das Gewichtsverhältnis von Dehydroxanthan Gum zum Gesamtanteil von Xanthan Gum und/oder Carrageenan von 10:1 bis 1:1, bevorzugt von 8:1 bis 1,5:1 und insbesondere bevorzugt 5:1 bis 2:1 beträgt. 7. Hydrogel or use according to one of the preceding claims, characterized in that the weight ratio of dehydroxanthan gum to the total proportion of xanthan gum and/or carrageenan is from 10:1 to 1:1, preferably from 8:1 to 1.5:1 and in particular preferably 5:1 to 2:1.
8. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass der Gesamtanteil von Wasser mindestens 70 Gew.-%,
bevorzugt mindestens 75 Gew.-% und insbesondere bevorzugt mindestens 77 Gew.- %, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. 8. Hydrogel or use according to any one of the preceding claims, characterized in that the total proportion of water is at least 70% by weight, preferably at least 75% by weight and particularly preferably at least 77% by weight, based on the total weight of the hydrogel.
9. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass der Gesamtanteil von Wasser weniger als 99 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. 9. Hydrogel or use according to one of the preceding claims, characterized in that the total proportion of water is less than 99% by weight, based on the total weight of the hydrogel.
10. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass Hydrogel frei von Polymeren, welche aus einer Homo- oder Copolymerisation mit Vinylpyrrolidon, Acryl- und/oder Methacrylsäure erhalten werden, ist. 10. Hydrogel or use according to one of the preceding claims, characterized in that the hydrogel is free from polymers which are obtained from a homo- or copolymerization with vinylpyrrolidone, acrylic and/or methacrylic acid.
11. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass das Hydrogel ein oder mehrere kurzkettige Polyole aufweisend 2 bis 8 Kohlenstoffatome enthält. 11. Hydrogel or use according to any one of the preceding claims, characterized in that the hydrogel contains one or more short-chain polyols having 2 to 8 carbon atoms.
12. Hydrogel oder Verwendung nach Anspruch 11 dadurch gekennzeichnet, dass der Anteil der Polyole aufweisend 1 bis 30 Gew.-%, bevorzugt von 2 bis 23 Gew.-% und insbesondere bevorzugt von 3 bis 20 Gew.-%, bezogen auf das Gesamtgewicht des Hydrogels, beträgt. 12. The hydrogel or use as claimed in claim 11, characterized in that the proportion of the polyols is 1 to 30% by weight, preferably 2 to 23% by weight and particularly preferably 3 to 20% by weight, based on the total weight of the hydrogel.
13. Hydrogel oder Verwendung nach Anspruch 11 oder 12 dadurch gekennzeichnet, dass die Polyole aufweisend 2 bis 8 Kohlenstoffatome gewählt sind aus der Gruppe bestehend aus Glycerin, Methylpropanediol, Propylene Glycol, 1,2- Hexanediol, Caprylyl Glycol, Butylene Glycol und Pentylene Glycol. 13. Hydrogel or use according to claim 11 or 12, characterized in that the polyols having 2 to 8 carbon atoms are selected from the group consisting of glycerol, methylpropanediol, propylene glycol, 1,2-hexanediol, caprylyl glycol, butylene glycol and pentylene glycol.
14. Hydrogel oder Verwendung nach einem der vorhergehenden Ansprüche dadurch gekennzeichnet, dass das Hydrogel 1,2- Hexanediol enthält, wobei es bevorzugt ist, wenn der Anteil von 1,2- Hexanediol von 0,2 bis 2 Gew.-%, bevorzugt von 0,5 bis 1,5 und insbesondere bevorzugt von 0,7 bis 1,3 Gew.-% beträgt, bezogen auf das Gesamtgewicht des Hydrogels, beträgt.
14. hydrogel or use according to any one of the preceding claims, characterized in that the hydrogel contains 1,2-hexanediol, it being preferred if the proportion of 1,2-hexanediol from 0.2 to 2 wt .-%, preferably from is from 0.5 to 1.5 and more preferably from 0.7 to 1.3% by weight based on the total weight of the hydrogel.
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DE102021205299 | 2021-05-25 | ||
DE102021209006.0A DE102021209006A1 (en) | 2021-05-25 | 2021-08-17 | Hydrogels with biopolymers |
PCT/EP2022/064073 WO2022248486A1 (en) | 2021-05-25 | 2022-05-24 | Hydrogels including biopolymers |
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DE102005056497A1 (en) | 2005-11-28 | 2007-05-31 | Beiersdorf Ag | Transparent or translucent gels |
DE102008029849A1 (en) * | 2008-06-25 | 2009-12-31 | Henkel Ag & Co. Kgaa | Compositions for shaping keratinic fibers based on a natural, holding polymer combination |
DE102016003804A1 (en) * | 2016-03-25 | 2017-09-28 | Laverana Gmbh & Co. Kg | Natural cosmetic preparation for the care of the skin of the sleeping human |
KR102238886B1 (en) * | 2020-04-13 | 2021-04-13 | 주식회사 피플앤코 | Oxidative hair dye composition with gel type |
DE102020205086A1 (en) * | 2020-04-22 | 2021-10-28 | Beiersdorf Aktiengesellschaft | Transparent cosmetic gel |
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