EP4225501A4 - System zur bestimmung eines biologischen zustands und kartusche dafür - Google Patents

System zur bestimmung eines biologischen zustands und kartusche dafür Download PDF

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Publication number
EP4225501A4
EP4225501A4 EP21877143.4A EP21877143A EP4225501A4 EP 4225501 A4 EP4225501 A4 EP 4225501A4 EP 21877143 A EP21877143 A EP 21877143A EP 4225501 A4 EP4225501 A4 EP 4225501A4
Authority
EP
European Patent Office
Prior art keywords
determining
biological state
cartridge therefor
therefor
cartridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21877143.4A
Other languages
English (en)
French (fr)
Other versions
EP4225501A1 (de
Inventor
Ilan SEMMEL
Warren Edward FARNAM III
Eric STIMPSON
Zion Botesazan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accellix Ltd
Original Assignee
Accellix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accellix Ltd filed Critical Accellix Ltd
Publication of EP4225501A1 publication Critical patent/EP4225501A1/de
Publication of EP4225501A4 publication Critical patent/EP4225501A4/de
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
EP21877143.4A 2020-10-07 2021-10-07 System zur bestimmung eines biologischen zustands und kartusche dafür Pending EP4225501A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063088470P 2020-10-07 2020-10-07
PCT/IL2021/051208 WO2022074657A1 (en) 2020-10-07 2021-10-07 System for determining a biological condition and cartridge therefor

Publications (2)

Publication Number Publication Date
EP4225501A1 EP4225501A1 (de) 2023-08-16
EP4225501A4 true EP4225501A4 (de) 2024-10-30

Family

ID=81125736

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21877143.4A Pending EP4225501A4 (de) 2020-10-07 2021-10-07 System zur bestimmung eines biologischen zustands und kartusche dafür

Country Status (6)

Country Link
EP (1) EP4225501A4 (de)
JP (1) JP7820071B2 (de)
KR (1) KR20230079276A (de)
CN (1) CN116438455B (de)
AU (2) AU2021356770B2 (de)
WO (1) WO2022074657A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118028094A (zh) * 2024-03-29 2024-05-14 中国科学院过程工程研究所 一种核酸检测系统
CN118048223B (zh) * 2024-03-29 2025-01-17 中国科学院过程工程研究所 一种核酸提取装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329142A1 (en) * 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US20150158026A1 (en) * 2006-06-23 2015-06-11 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US20170113221A1 (en) * 2014-06-11 2017-04-27 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US20180015474A1 (en) * 2015-02-02 2018-01-18 Atlas Genetics Limited Instrument for performing a diagnostic test on a fluidic cartridge

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9052309B2 (en) * 2010-12-03 2015-06-09 Abbott Point Of Care Inc. Ratiometric immunoassay method and blood testing device
AU2013353832B2 (en) * 2012-12-03 2017-05-11 The Secretary Of State For Environment, Food And Rural Affairs Device and apparatus
CN105051538B (zh) * 2012-12-17 2018-06-15 伦珂德克斯有限公司 用于检测生物状况的系统和方法
JP2016130652A (ja) * 2015-01-13 2016-07-21 株式会社フジクラ 検査デバイス、検査方法及び検査装置
SG10202005427PA (en) * 2015-04-24 2020-07-29 Mesa Biotech Inc Fluidic test cassette
KR101765474B1 (ko) * 2015-11-26 2017-08-07 경희대학교 산학협력단 바이러스 진단 키트
CN117258862B (zh) * 2018-12-13 2025-03-04 迪亚莱博（张家港）生物科技有限公司 一种微流控芯片的制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329142A1 (en) * 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US20150158026A1 (en) * 2006-06-23 2015-06-11 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US20170113221A1 (en) * 2014-06-11 2017-04-27 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US20180015474A1 (en) * 2015-02-02 2018-01-18 Atlas Genetics Limited Instrument for performing a diagnostic test on a fluidic cartridge

Also Published As

Publication number Publication date
CN116438455B (zh) 2026-01-30
EP4225501A1 (de) 2023-08-16
JP2023545415A (ja) 2023-10-30
AU2021356770A1 (en) 2023-06-01
JP7820071B2 (ja) 2026-02-25
AU2021356770B2 (en) 2025-05-08
CN116438455A (zh) 2023-07-14
WO2022074657A1 (en) 2022-04-14
AU2025210862A1 (en) 2025-08-21
KR20230079276A (ko) 2023-06-05

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RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 15/10 20060101ALI20240926BHEP

Ipc: G01N 33/543 20060101ALI20240926BHEP

Ipc: G01N 15/14 20060101ALI20240926BHEP

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Ipc: G01N 33/53 20060101ALI20240926BHEP

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