EP4213912A1 - Dispositif d'administration d'une perfusion ou transfusion, système comprenant un tel dispositif et procédé de commande d'un tel dispositif - Google Patents

Dispositif d'administration d'une perfusion ou transfusion, système comprenant un tel dispositif et procédé de commande d'un tel dispositif

Info

Publication number
EP4213912A1
EP4213912A1 EP21777985.9A EP21777985A EP4213912A1 EP 4213912 A1 EP4213912 A1 EP 4213912A1 EP 21777985 A EP21777985 A EP 21777985A EP 4213912 A1 EP4213912 A1 EP 4213912A1
Authority
EP
European Patent Office
Prior art keywords
liquid
pump
infusion
container
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21777985.9A
Other languages
German (de)
English (en)
Inventor
Andreas Katerkamp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B Braun Melsungen AG
Original Assignee
B Braun Melsungen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B Braun Melsungen AG filed Critical B Braun Melsungen AG
Publication of EP4213912A1 publication Critical patent/EP4213912A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14228—Pumping with an aspiration and an expulsion action with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1411—Drip chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A61M5/1409—Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • A61M5/16859—Evaluation of pressure response, e.g. to an applied pulse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate
    • A61M5/16881—Regulating valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M2005/1401—Functional features
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • A61M2005/1657—Filter with membrane, e.g. membrane, flat sheet type infusion filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0028—Special media to be introduced, removed or treated fluid entering a filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
    • A61M2205/106—General characteristics of the apparatus with powered movement mechanisms reciprocating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/125—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated filters
    • A61M2205/126—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated filters with incorporated membrane filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3337—Controlling, regulating pressure or flow by means of a valve by-passing a pump
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1413—Modular systems comprising interconnecting elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1414—Hanging-up devices

Definitions

  • Device for administering an infusion or transfusion comprising such a device and method for controlling such a device
  • infusions and transfusions are used for therapeutic purposes.
  • Infusions and transfusions are used to administer fluids to a patient.
  • infusions can be used to administer liquid medicines (solutions of active substances, etc.).
  • An infusion or transfusion set is understood to mean a product with which a medical infusion can be administered or a medical transfusion carried out or a comparable administration of a liquid can be carried out.
  • the terms "infusion set”, “infusion or transfusion set” or “infusion set” are also common for an infusion or transfusion set, whereby when using the terms "infusion set” and “infusion set” it should not be ruled out that the product so designated for example, a transfusion can also be carried out.
  • An infusion or transfusion set usually has a tube and often a drip chamber.
  • the infusion or transfusion set can optionally include other components, for example a flow regulator for controlling the flow rate of the liquid, such as a roller clamp.
  • the liquid to be administered as part of an infusion or transfusion is provided in a container.
  • the container can be an infusion bottle, an infusion bag, a blood unit, etc., for example. If a drip chamber is present, it is usually connected to the reservoir via a reservoir connection, so that the liquid from the reservoir can pass into the drip chamber.
  • a drop former is provided inside the drip chamber, which causes the liquid from the container to enter the drip chamber in the form of drops of a standardized size.
  • the container connection can be, for example, a piercing device such as a hollow spike, with which a septum closing the container can be punctured and which typically has a number of channels in its interior.
  • a lancing device is generally referred to as a "spike”.
  • Other systems are also known for connecting the drip chamber to the container, for example coupling systems, which do not allow the drip chamber and the container to be separated again after they have been connected to one another.
  • the drip chamber is in fluid communication with an end of the tubing, allowing liquid from the drip chamber to enter the tubing. If no drip chamber is used, the hose is connected directly to the container or to a suitable container connection.
  • the tube has a connection for a patient access (eg venous cannula or venous catheter).
  • a patient access eg venous cannula or venous catheter.
  • the connection for the patient access is hereinafter referred to as "patient connection”.
  • patient connection can optionally also be considered as part of the infusion or transfusion set.
  • a drip chamber establishes the connection between the hose and the container.
  • the devices that ensure the ventilation of the system are integrated into the drip chamber.
  • the drip chamber usually has a ventilation device with a ventilation valve that can be operated manually or with an automatic ventilation valve and a ventilation channel that is open to the inside of the drip chamber.
  • Different embodiments of the ventilation device based on different valve types and with and without ventilation filters are known in the prior art, for example manual ventilation devices that have a manually operated flap as ventilation valve, and automatic ventilation valves that have a non-return valve as ventilation valve.
  • the manual or automatic ventilation device not integrated in a drip chamber but placed in another suitable position of the system.
  • the present invention is compatible with manual and automatic aerators. Particularly if the container in which the liquid to be administered is placed is collapsible, the use of a drip chamber or an aeration device can also be dispensed with because it is then not necessary to let air flow into the system for pressure equalization.
  • peristaltic pump infusion or pump transfusion In addition to the technique of gravity infusion or gravity transfusion, in which the liquid is conveyed from the container to the patient access solely by the effect of gravity, the technique of pump infusion or pump transfusion has become established.
  • pump infusion or pump transfusion the liquid is conveyed using a pump.
  • a peristaltic pump for example, can be used as the pump, which is connected to a region of the tube and periodically deforms it in order to generate a peristaltic pumping movement.
  • Such peristaltic pumps are advantageous because no components of the pump come into contact with the liquid, so that there is no risk of contamination through the use of the pump.
  • peristaltic pumps are easy to use. In particular, it is easy to connect a tube to the pump and to disconnect this connection again after the infusion has ended.
  • peristaltic infusion or transfusion pumps generally have a housing with an open channel or slot into which the tube is inserted.
  • This liquid-retaining filter membrane is arranged in the fluid channel through which the liquid passes from the container to the patient access.
  • the liquid-retaining filter membrane can be arranged at the bottom of the drip chamber, ie in the area of its outlet. However, it can also be arranged at another point of the hose.
  • the liquid-retaining membrane has the function of a membrane that resists the draining of the liquid column located in the tube below the liquid-retaining membrane. The function of the liquid retaining membrane is described in detail below.
  • the pumps used usually have a pressure measuring device that can record the pressure of the liquid in the area of the hose on the pump inlet side.
  • the area of the hose on the pump inlet side is understood to mean the area of the hose that is located upstream of the pump.
  • the liquid-retaining filter membrane is preferably arranged upstream of the pump.
  • the region of the hose on the pump inlet side is understood to be the region between the pump and the liquid-retaining filter membrane. If the container or the drip chamber is empty, the pressure of the liquid in the drops area of the hose on the pump inlet side.
  • a control device which receives signals from the pressure measuring device, is set up to emit an acoustic and/or visual alarm signal and/or switch off the pump when it is determined that the infusion or transfusion has ended.
  • the further steps can consist, for example, of following a further infusion or transfusion.
  • the further steps can also consist, for example, in the logging of the completion of the infusion or transfusion and the uncoupling of the infusion or transfusion set from the patient. In any case, it is necessary for medical staff to be on site to hear the alarm signal and take further steps.
  • an object of the invention is to provide an improved device for administering an infusion or transfusion, an improved system comprising such a device and an improved method for controlling such a device.
  • the device according to the invention is a device for administering an infusion or transfusion of a liquid from a container.
  • the device according to the invention comprises a pump for conveying the liquid via a line, which has a liquid-retaining filter membrane, to a patient connection.
  • the device according to the invention also includes a pressure measuring device for acquiring measured values in accordance with a pump upstream pressure, which is present inside the line between the pump and the liquid-retaining filter membrane.
  • the device according to the invention also includes a control device.
  • the control device is set up to use the measured values to determine a change in the pressure on the pump inlet side.
  • the control device is also set up to use the change in the pressure on the pump inlet side to determine whether the pumping of the liquid should be ended.
  • the control device is also set up to generate a control signal when the delivery of the liquid is to be ended.
  • the control device is also set up, based on the control signal, to output a communication signal to a data connection between the device and a device that is set up for reading in the communication signal and/or to switch the device from a first active operating state to a second active operating state based on the control signal to move.
  • the data connection can be wireless, e.g. via WIFI.
  • the device that is set up for reading in the communication signal can be an external device, i.e. a device outside of the device according to the invention.
  • This device can also be an internal device, for example a display and/or an acoustic signal transmitter arranged in the area of the pump, in particular in the same housing as the pump.
  • This device can also be an additional pump or a switchable multi-way valve.
  • an “active operating state” is an operating state in which the device is pumping a liquid. That is, the inactive state of the device, with no pump performing any activity, is not an active operational state.
  • the control device is set up to cause the device to pump another liquid from another container to the patient connection on the basis of the control signal.
  • control device is set up, on the basis of the control signal, to output a communication signal to a data connection between the device and a device that is set up to read in the communication signal.
  • This device is preferably an external device, so that the communication signal can cause a device outside of the device according to the invention to perform an activity.
  • the data connection can be wireless, e.g. via WIFI.
  • the computer-aided information system can serve various purposes.
  • the computer-aided information system can be used to automatically log the end of the infusion and/or to note it in the patient's electronic medical record.
  • the computer-aided information system can also be used to inform the responsible medical staff that the infusion has ended, without the medical staff having to be on site.
  • the information can be transmitted, for example, to a mobile device (mobile phone, etc.).
  • a medical analysis device can be prompted to perform a medical examination on the patient that is required immediately or a predetermined time after administration of the infusion. In this case, the medical examination does not have to be initiated in a separate step by the medical staff.
  • This device can also be another device for administering an infusion or transfusion, which starts administering when it receives an appropriate communication signal. In this way, it is possible to administer several infusions or transfusions without the medical staff having to intervene between the individual infusions or transfusions.
  • This device can be an external device, i.e. a device outside the device according to the invention.
  • This device can also be an internal device, for example a display and/or an acoustic signal transmitter arranged in the area of the pump, in particular in the same housing as the pump.
  • This device can also be an additional pump or a switchable multi-way valve.
  • control device is set up, on the basis of the control signal, to cause the device to deliver another liquid from another container to the patient connection.
  • control device can be set up to cause the device to first administer a liquid from a container, then, based on the control signal, to cause a medical analysis device to carry out a medical examination on the patient in order to determine whether a further liquid from a further container is to be administered, and optionally the same device or causing another device to deliver another fluid from another container to the patient port.
  • the system according to the invention is a system that includes a device according to the invention and at least one infusion or transfusion set.
  • the at least one infusion or transfusion set comprises a line with a liquid-retaining filter membrane and a patient connection.
  • the system according to the invention provides the devices with which a liquid can be conveyed from a container to a patient access point, with the advantageous effects of the invention being able to be achieved.
  • the line preferably has a drip chamber in which the liquid-retaining filter membrane is arranged in the outlet area.
  • the pressure measuring device preferably acquires the measured values intermittently in accordance with the pressure on the pump inlet side, with the same time intervals preferably lying between the acquisition of two consecutive measured values.
  • the pump is a peristaltic pump.
  • the method according to the invention is a method for controlling a device for administering an infusion or transfusion of a liquid from a container, the device comprising:
  • a pump for delivering the liquid via a line, which has a liquid-retaining filter membrane, to a patient connection
  • a pressure measuring device for acquiring measured values corresponding to a pressure on the pump inlet side which is present inside the line between the pump and the drip chamber
  • the control device is set up to use the measured values to determine a change in the pressure on the pump inlet side.
  • the control device is also set up to use the change in the pressure on the pump inlet side to determine whether the pumping of the liquid should be ended.
  • the control device is also set up to generate a control signal when the delivery of the liquid is to be ended.
  • the control device is also set up, based on the control signal, to output a communication signal to a data connection between the device and a device that is set up for reading in the communication signal and/or to switch the device from a first active operating state to a second active operating state based on the control signal to move, for example by causing the device to deliver another liquid from another container to the patient connection.
  • the data connection can be wireless, e.g. via WIFI.
  • the method according to the invention makes it possible, in particular, to control the device according to the invention in order to achieve the advantageous effects of the invention.
  • FIG. 1 shows a device according to a first exemplary embodiment of the invention and a system made up of the device according to the first exemplary embodiment and an infusion and transfusion set and a device that is set up for reading in the communication signal, and also shows a vessel.
  • 2 shows a device according to a second exemplary embodiment of the invention and a system made up of the device according to the second exemplary embodiment and an infusion and transfusion set, and also shows two vessels.
  • FIG 3 shows the device according to the second exemplary embodiment of the invention and a system made up of the device according to the second exemplary embodiment and two infusion and transfusion sets, and also shows two vessels.
  • FIG. 4 shows a device according to a third exemplary embodiment of the invention and a system made up of the device according to the third exemplary embodiment and an infusion and transfusion set, and also shows two vessels.
  • FIG 5 shows a device according to a fourth embodiment of the invention.
  • FIG. 1 shows a device 1 according to a first exemplary embodiment of the invention and an infusion or transfusion set 2 which is not part of the device according to the invention.
  • the device 1 and the infusion or transfusion set 2 together represent an exemplary embodiment of the system according to the invention.
  • FIG. 1 also shows a device 3 which is set up for reading in the communication signal.
  • the device 3 is shown as an external device 3 which is not part of the system according to the invention.
  • a container 4 in which a liquid to be administered to a patient is provided.
  • the container 4 is not part of the system according to the invention.
  • the container 4 can be an infusion bottle, an infusion bag, a blood unit, etc., for example.
  • Drip chamber 21 with an entrance 211 through which the liquid into the
  • Drip chamber 21 can occur, and an outlet 212 through which the liquid can get into the hose leading to the patient.
  • the entrance 211 is at the top, while the exit 212 is at the bottom.
  • the drip chamber 21 has a container connection 22 for connection to a container 4, so that the liquid from the container 4 can reach the drip chamber 21.
  • a drop former (not shown in FIG. 1) is provided inside the drip chamber 21 in the area of the inlet 211, which causes the liquid to enter in the form of drops of standardized size.
  • the container connection 22 shown in FIG. 1 is a lancing device with which a septum closing the container 4 can be pierced and which typically has a number of channels in its interior. Such a lancing device is generally referred to as a "spike".
  • the container connection can be designed, for example, in the form of another coupling system.
  • the drip chamber 21 preferably has an aeration device that is not shown in FIG. 1 .
  • a liquid-retaining filter membrane 23 is arranged in the area of the outlet 212 of the drip chamber.
  • the liquid-retaining filter membrane 23 has the function of preventing the passage of fluid when there is no liquid or only a low liquid level above the membrane. This prevents air from passing through the membrane, ensuring that no air enters the patient's bloodstream.
  • the membrane has a porous structure and the liquid flowing through the membrane flows through the pores or through the channels formed by the pores.
  • the function of such a membrane is explained according to a theory as follows, although the present invention is not limited to the liquid-retaining membrane functioning according to this theory: When there is at least a certain amount of liquid above the membrane or liquid is dropped onto the membrane from above, the theory is that the weight of this liquid provides sufficient pressure to allow the liquid to flow through the pores or channels. If there is no liquid above the membrane or only a slight supernatant of liquid, the liquid is held in the pores or channels as a result of capillary forces and air can be prevented from flowing through the pores or channels.
  • the membrane preferably comprises a hydrophilic material because the capillary effect is then more pronounced than in the case of a non-hydrophilic material.
  • the term "bubble point pressure" is also used for the breakthrough pressure.
  • the breakthrough pressure must exceed the vacuum created by the liquid column to prevent the liquid column from draining and air from entering the hose.
  • the dimensions of the membrane as well as its material and structure are selected for gravity infusion and adapted to the infusion liquid and the length of the hose so that the breakthrough pressure is sufficient and the membrane can prevent the liquid column from flowing out.
  • the breakthrough pressure for some commercially available infusion sets with a hose length of about 150 cm is at least 20 kPa.
  • 20 kPa corresponds to a water column of 200 cm. Since the hose length and thus the liquid column are shorter, the flow of gravity infusion is automatically stopped as soon as the container or drip chamber is empty.
  • the pump is switched off automatically as soon as the pressure difference between the top and bottom of the membrane has a predetermined value is less than the breakthrough pressure.
  • the pump can be set to switch off at a pressure drop of 17 kPa (corresponding to a pressure in the tubing of -17 kPa compared to the pressure otherwise prevailing during the infusion).
  • the infusion or transfusion set 2 also includes a tube 24 .
  • the tube 24 is connected to the outlet 212 of the drip chamber 21 .
  • the tube 24 is connected directly to the container connection 22 or directly to the container 4 .
  • the liquid-retaining filter membrane 23 is not arranged in the area of the outlet of a drip chamber, but in a separate element 23a along the tube 24.
  • the liquid must in any case pass through the liquid-retaining filter membrane 23, 23a in order to be able to flow from the container to the patient. It is also possible for several liquid-retaining filter membranes 23, 23a to be arranged along the hose 24.
  • the infusion or transfusion set 2 also includes a patient connection 25 which is connected to one end of the hose 24 .
  • the patient connector 25 provides a port for patient access.
  • the patient access is not shown in FIG.
  • the patient access can be a venous cannula, a venous catheter, etc., for example.
  • the patient access can optionally also be considered as part of the infusion or transfusion set.
  • the hose 24 is connected directly to the container 4 or to a suitable container connection.
  • the liquid-retaining membrane 23a is then positioned along the tube 24 at a suitable location.
  • the infusion or transfusion set 2 can optionally include further components, for example a flow regulator 26 for shutting off the tube 24 and/or to control the flow rate of the liquid.
  • a flow regulator 26 for shutting off the tube 24 and/or to control the flow rate of the liquid.
  • the optional flow regulator 26 is exemplified in Figure 1 as a roller clamp.
  • the infusion or transfusion set 2 provides a connection between a container 4 in which the liquid to be administered is provided and a patient access.
  • liquid flows from the container 4 into the hose 24 and through this hose 24 to the patient connection 25, which is connected to the patient access.
  • a drip chamber 21 is optionally provided, which provides a connection between the hose 24 and the container connection 22, which is connected to the container 4.
  • the liquid penetrates the liquid-retaining filter membrane 23, 23a.
  • the liquid-retaining filter membrane 23, 23a is preferably arranged upstream of the pump described below.
  • the infusion or transfusion set 2 is therefore an example of a line which has a liquid-retaining filter membrane 23, 23a and which is used to deliver a liquid to a patient access connected to the patient connection 25.
  • the device 1 includes a pump 11 .
  • the pump 11 is optionally arranged in a housing 12 .
  • the pump 11 is, for example, a peristaltic pump which can be connected to a portion of the hose 24 in order to periodically deform it so that a peristaltic pumping movement is produced.
  • the peristaltic pumping movement of the wall of the hose 24 conveys liquid through the hose in the direction of the patient connection 25 .
  • the device 1 also includes a pressure measuring device 13 for acquiring measured values corresponding to a pressure on the pump inlet side which is present inside the line, ie inside the hose 24, between the pump and the liquid-retaining filter membrane.
  • the pressure measuring device 13 and the pump 11 are preferably arranged in the same housing 12 . This ensures that the pressure measuring device 13 records the pressure values at the correct position along the hose 24 . Furthermore, this makes it easy for the user to handle, since the user only has to connect the hose 24 to a device whose housing 12 contains the pump 11 and the pressure measuring device 13 .
  • the pressure measuring device 13 can be, for example, a measuring device that determines the size of the cross section of the elastic hose 24 in the area in front of the pump.
  • the pressure measuring device 13 can, for example, be a measuring device that determines the resistance of the elastic hose 24 to a compression force in the area in front of the pump. From the cross section and the resistance to deformation, conclusions can be drawn about the pressure prevailing inside the tube 24 .
  • measuring sensors are possible, which protrude into the interior of the tube 24 and determine the pressure directly in contact with the liquid.
  • the device 1 also includes a control device 14.
  • a control device 14 In the specific exemplary embodiment shown in FIG.
  • control device 14 of the pump 11 can also be arranged within the housing 12 .
  • the control device 14 can include, for example, one or more processors, one or more memories, electrical connections, connections, interfaces and other electronic and electrical components.
  • the control device 14 is set up to use the measured values to determine a change in the pressure on the pump inlet side.
  • the control device 14 is also set up to use the change in the pressure on the pump inlet side to determine whether the pumping of the liquid should be ended.
  • the control device 14 is also set up to generate a control signal when the delivery of the liquid is to be ended.
  • the control device 14 is also set up, on the basis of the control signal, to send a communication signal to a data connection 31 between the device 1 and a device 3, which is used for reading in the Communication signal is set up to output.
  • the data connection 31 can be wireless, for example using WIFI.
  • the liquid that enters the tube 24 from the container 4, optionally via a drip chamber 21, is pumped through the tube 24 by means of the pump 11 conveyed through to the patient, ie to the patient connection 25, which is connected to the patient access.
  • the liquid enters the patient's body, for example into a vein, through the patient access.
  • the pressure measuring device 13 records measured values. The readings are a measure of the pressure on the pump inlet side that is present inside the line, i.e. inside the hose 24, between the pump 11 and the liquid-retaining filter membrane 23, 23a.
  • the pressure measuring device can record the measured values continuously or intermittently.
  • the pump 11 When the liquid to be administered has been completely removed from the container 4, the pump 11 first delivers liquid through the hose 24. The liquid level in the drip chamber 21 or in the hose 24 continues to fall. This happens until the liquid level has reached the liquid-retaining filter membrane 23, 23a. When the liquid level has reached the liquid-retaining filter membrane 23, 23a, the pressure of the liquid in the pump inlet-side area of the hose between the liquid-retaining filter membrane 23, 23a and the pump 11 drops, since the pump 11 continues to suck from this area. The drop in the pressure on the pump inlet side is recognized by the control device 14 on the basis of the measured values recorded by the pressure measuring device 13 . The control device 14 therefore detects a change in the pressure on the pump inlet side, in the present case in the form of a drop.
  • the control device On the basis of the change in the pressure on the pump inlet side, the control device also determines whether the pumping of the liquid should be ended. This is the case when the control device establishes that a criterion related to the change in pressure or to the measured values is met.
  • the criterion can be, for example: Falling below one predetermined threshold of pressure; Falling below a predetermined threshold value of the difference quotient of the pressure formed with time increments; Falling below a predetermined threshold value of the differential quotient formed by the time derivative of the pressure.
  • control device 14 If the control device 14 has determined that the delivery of the liquid is to be ended, it generates a corresponding control signal.
  • control device 14 If the control device 14 has generated a corresponding control signal, it outputs a corresponding communication signal to a data connection 31 .
  • the control signal is therefore a signal which is processed within the control device 14 and which causes a communication signal to be output.
  • the control signal is a command that causes that part of the control device 14 whose task is to output signals to issue the communication signal by outputting it to the data connection 31 .
  • the data connection 31 is not part of the system according to the invention.
  • the data connection 31 is used to connect the control device 14 and the device 3, which is set up to read in the communication signal.
  • the data connection 31 can be a cable, an optical data conductor, a wireless connection, etc., for example.
  • the data connection 31 can in particular be a wireless connection using WIFI.
  • the device 3 is set up to read in the communication signal. This means that the control device 14 is conversely set up to output a communication signal that can be read in by the device 3 .
  • the device 3 can be, for example, a preferably electronic control unit, a computer, a computer network, a medical analysis device, etc.
  • the device 3 is prompted by the communication signal, data for example in the patient's electronic medical record or in a directory in which infusions or transfusions are logged, to save or to initiate a further action desired after the infusion or transfusion.
  • the further action can be, for example, the administration of another infusion or transfusion through another device or the carrying out of a medical examination.
  • FIG. 2 shows a device 100 according to a second exemplary embodiment of the invention and an infusion or transfusion set 200 which is not part of the device according to the invention.
  • the device 100 and the infusion or transfusion set 200 together represent an exemplary embodiment of the system according to the invention.
  • FIG. 4 In addition to the device 100 and the infusion or transfusion set 200, two containers 4 and 4', in each of which a liquid to be administered to a patient can be made available, are shown in FIG.
  • the containers 4 and 4' are not part of the system according to the invention.
  • the containers 4 and 4' can be, for example, infusion bottles, infusion bags, blood supplies, etc.
  • the infusion or transfusion set 200 specifically shown in FIG. 2 has two hoses 24 and 24 ′, which combine at a hose connection point 27 to form a common piece of hose 28 .
  • the hoses 24 and 24' are two feed lines which lead to the hose connection point 27 in the direction of flow.
  • the common piece of tubing 28 is a derivation leading away from the tubing junction.
  • the common piece of tubing 28 is with a patient connection 25 connected. Otherwise, the hoses 24 and 24' correspond to the hose 24 described above in connection with the first exemplary embodiment.
  • the patient connection 25 provides a connection for a patient access. The patient access is not shown in FIG.
  • a drip chamber 21 or 2T is optional for each of the tubes 24 or 24'.
  • the details of the drip chamber reference is made to the above description of the first exemplary embodiment.
  • a liquid-retaining filter membrane 23, 23' is arranged in each case in the region of the outlet 212, 212' of the drip chambers 21, 2T shown in FIG.
  • the liquid-retaining filter membrane 23, 23' is not arranged in the area of the outlet of a drip chamber, but in a separate element 23a, 23a' along the tube 24, 24'.
  • the liquid must pass through the liquid-retaining filter membrane 23, 23', 23a, 23a' in order to be able to flow from the container to the patient. It is also possible for several liquid-retaining filter membranes to be arranged along the hose 24, 24'.
  • the infusion or transfusion set 200 can optionally include further components, for example one or more flow regulators 26, 26' for shutting off and/or controlling the flow rate of the liquid.
  • the optional flow regulators 26, 26' are shown in FIG. 2 as roller clamps by way of example.
  • the infusion or transfusion set 200 provides a connection between the containers 4 and 4', in each of which a liquid to be administered is provided, and a patient access.
  • liquid is conveyed from one of the containers 4 and 4' to the patient connection 25, which is connected to the patient access.
  • the liquid penetrates the respective liquid-retaining filter membrane 23, 23', 23a, 23a'.
  • the liquid-retaining filter membranes 23, 23', 23a, 23a' are preferably arranged upstream of the pumps described below.
  • the infusion or transfusion set 200 is therefore an example of a branched line which has a liquid-retaining filter membrane and which is used to deliver liquids to a patient access connected to the patient connection 25 .
  • the device 100 comprises two pumps 111 and 121.
  • the pumps 111 and 121 are each optionally arranged in a housing 112, 122.
  • the pumps 111 and 121 are, for example, peristaltic pumps. With regard to the details relating to the peristaltic pumps, reference is made to the above description of the first exemplary embodiment.
  • the device 100 also includes a pressure measuring device 113, which is used to record measured values corresponding to a pressure on the pump inlet side which is inside the line, ie inside the hose 24, between the pump 111 and the respective liquid-retaining filter membrane 23, 23', 23a, 23a'. present.
  • the device 100 preferably comprises two pressure measuring devices 113 and 123, each of which is used to record measured values corresponding to a pressure on the pump inlet side that is inside the line, ie inside the hose 24 or 24', between the respective pump 111, 121 and the respective liquid-retaining filter membrane 23, 23', 23a, 23a' is present.
  • the pressure measuring devices 113 and 123 reference is made to the above description of the first exemplary embodiment.
  • the pressure measuring device 113 and the pump 111 are preferably arranged in a common housing 112 and the pressure measuring device 123 and the pump 121 in a common housing 122 .
  • the device 100 also includes a control device 114.
  • the control device 114 can also be arranged in one of the housings 112 and 122 .
  • both pumps 111 and 121 are arranged in a common housing, in which the control device 114 can also be arranged.
  • the control device 114 is set up to determine a change in the pressure on the pump inlet side on the basis of the measured values which are recorded by the pressure measuring device 113 .
  • the control device 114 is also set up to use the change in the pressure on the pump inlet side to determine whether the delivery of the liquid from the first container 4 should be ended.
  • the control device 114 is also set up to generate a control signal when the delivery of the liquid is to be ended.
  • the control device is also set up, on the basis of the control signal, to cause the device 100 to deliver another liquid from another container 4 ′ to the patient, ie to the patient connection 25 .
  • the liquid that enters the tube 24 from the first container 4, if necessary via a drip chamber 21, is pumped through the tube by the pump 111 24 through to the patient, ie to the patient connection 25, which is connected to the patient access, promoted.
  • the liquid enters the patient's body, for example into a vein, through the patient access.
  • the pressure measuring device 113 records measured values. The readings are a measure of the pump inlet side pressure that exists inside the line, i.e. inside the hose 24, between the pump 111 and the liquid-retaining filter membrane 23, 23a.
  • the pressure measuring device 113 can record the measured values continuously or intermittently.
  • the pump 11 When the liquid to be administered has been completely removed from the first container 4, the pump 11 first delivers liquid through the hose 24. The liquid level in the drip chamber 21 or in the Hose 24 further and further off. This happens until the liquid level has reached the liquid-retaining filter membrane 23, 23a. When the liquid level has reached the liquid-retaining filter membrane 23, 23a, the pressure of the liquid in the pump inlet-side area of the hose between the liquid-retaining filter membrane 23, 23a and the pump 111 drops, since the pump 111 continues to suck from this area. The drop in the pressure on the pump inlet side is recognized by the control device 114 on the basis of the measured values recorded by the pressure measuring device 113 .
  • the control device 114 therefore determines a change in the pressure on the pump inlet side in the hose 24, in the present case in the form of a drop in pressure. Based on the change in the pressure on the pump inlet side, the control device 114 also determines whether the pumping of the liquid from the first container 4 is to be ended. This is the case when the control device establishes that a criterion related to the change in pressure or to the measured values is met.
  • the criterion can be, for example: the pressure falls below a predetermined threshold value; Falling below a predetermined threshold value of the difference quotient of the pressure formed with time increments; Falling below a predetermined threshold value of the differential quotient formed by the time derivative of the pressure.
  • control device 114 If the control device 114 has established that the conveying of the liquid from the first container is to be ended, it generates a corresponding control signal.
  • This control signal causes the device 100 to convey another liquid from a second container 4' to the patient connection.
  • FIG. 3 shows the device 100 according to the second exemplary embodiment of the invention and two infusion or transfusion sets 201 and 20T, which are not part of the device according to the invention.
  • the configuration shown in FIG. 3 corresponds to the configuration shown in FIG. 2 with the difference that instead of an infusion or transfusion set with two tubes that combine at a tube connection point, there are two separate infusion or transfusion sets 201 and 20T.
  • an infusion or transfusion set 200 with a branch is assigned to both pumps 111 and 121, while in the situation shown in FIG. 3 each pump 111 and 121 has its own infusion or transfusion set 201, 20T is assigned.
  • the infusion or transfusion sets 201 and 201' each have their own patient connection 25 or 25'.
  • the patient connections 25 and 25' each serve to connect to a patient access. For the rest, reference is made to the above description of the system shown in FIG.
  • the device according to the second exemplary embodiment has two pumps 111 and 121, which are each used to convey the liquid from one of the containers 4, 4' as part of an automatic sequential infusion or transfusion.
  • the device according to the invention has a corresponding number of pumps.
  • An infusion or transfusion set with a corresponding number of tubes is used together with the device.
  • a corresponding number of infusion or transfusion sets can be used.
  • the device according to the invention and the infusion or transfusion set with a corresponding number of hoses or the device according to the invention and a corresponding number of infusion or transfusion sets then each form systems according to the invention.
  • FIG 4 shows a device 1000 according to a third exemplary embodiment of the invention and an infusion or transfusion set 2000 that is not part of the device according to the invention.
  • the device 1000 and the infusion or transfusion set 2000 together represent an exemplary embodiment of the system according to the invention.
  • FIG. 4 shows two containers 4 and 4', in each of which a liquid to be administered to a patient can be made available.
  • the containers 4 and 4' are not part of the system according to the invention.
  • the containers 4 and 4' can be, for example, infusion bottles, infusion bags, blood supplies, etc.
  • the infusion or transfusion set 2000 shown specifically in FIG. 4 has two tubes 24 and 24 ′, which combine at a tube connection point 27 by a switchable multi-way valve 1015 to form a common piece of tube 28 .
  • the hoses 24 and 24' are two feed lines which lead to the hose connection point 27 in the direction of flow.
  • the common piece of tubing 28 is a derivation leading away from the tubing connection point 27 .
  • the common Tubing piece 28 is connected to a patient connection 25 . Otherwise, the hoses 24 and 24' correspond to the hose 24 described above in connection with the first exemplary embodiment.
  • the patient connection 25 provides a connection for a patient access.
  • the patient access is not shown in FIG.
  • the multi-way valve 1015 can be, for example, a multi-way solenoid valve and/or an actuator-operated multi-way tap.
  • a drip chamber 21 or 2T is optional for each of the tubes 24 or 24'.
  • the details of the drip chamber reference is made to the above description of the first exemplary embodiment.
  • a liquid-retaining filter membrane 23, 23' is arranged in each case in the region of the outlet 212, 212' of the drip chambers 21, 2T shown in FIG.
  • the liquid-retaining filter membrane 23a, 23a' is not arranged in the area of the outlet of a drip chamber, but in a separate element 23a, 23a' along the tube 24, 24'.
  • the liquid must pass through the liquid-retaining filter membrane 23, 23', 23a, 23a' in order to be able to flow from the container to the patient. It is also possible for several liquid-retaining filter membranes 23, 23', 23a, 23a' to be arranged along the hose 24, 24'.
  • the infusion or transfusion set 2000 can optionally include further components, for example one or more flow regulators 26, 26' for shutting off and/or controlling the flow rate of the liquid.
  • the optional flow regulators 26, 26' are shown in FIG. 4 as roller clamps by way of example.
  • the infusion or transfusion set 2000 provides a connection between the
  • Containers 4 and 4' in each of which a liquid to be administered is provided is ready and ready for patient access.
  • liquid is conveyed from one of the containers 4 and 4' to the patient, ie to the patient connection 25, which is connected to the patient access.
  • the liquid penetrates the respective liquid-retaining filter membrane 23, 23, 23a, 23a'.
  • the liquid-retaining filter membranes 23, 23', 23a, 23a' are preferably arranged upstream of the pump described below.
  • the infusion or transfusion set 2000 is therefore an example of a line which has a liquid-retaining filter membrane and which is used to convey liquids to a patient access port connected to the patient connection 25 .
  • the device 1000 includes a pump 1011 .
  • the pump 1011 is optionally arranged in a housing 1012 .
  • the pump 1011 is, for example, a peristaltic pump. With regard to the details relating to the peristaltic pumps, reference is made to the above description of the first exemplary embodiment.
  • the device 1000 also includes a pressure measuring device 1013 for acquiring measured values corresponding to a pressure on the pump inlet side which is inside the line, ie inside the hose piece 28 and the hose 24 or the hose 24' between the pump 1011 and the respective liquid-retaining filter membrane 23. 23', 23a, 23a' is present.
  • the pressure measuring device 1013 and the pump 1011 are preferably arranged in the same housing 1012 .
  • the device 1000 also includes a control device 1014.
  • the control device 1014 can also be arranged in the housing 1012 .
  • the control device 1014 is set up based on the measured values from the Pressure measuring device 1013 are detected to determine a change in the pressure on the pump inlet side.
  • the control device 1014 is also set up to use the change in the pressure on the pump inlet side to determine whether the delivery of the liquid from the first container 4 should be ended.
  • the control device is also set up 1014 to generate a control signal when the delivery of the liquid is to be ended.
  • the control device is also set up to cause the device 1000 to pump another liquid from another container 4 ′ to the patient connection 25 on the basis of the control signal.
  • the device 1000 includes a multi-way valve 1015.
  • the multi-way valve 1015 can be switched from a first position to a second position on the basis of the control signal.
  • the first position the path from the hose 24 into the piece of hose 28 is open and the path from the hose 24' into the piece of hose 28 is closed.
  • the second position the path from the hose 24 into the piece of hose 28 is closed and the path from the hose 24' into the piece of hose 28 is open.
  • the selector valve 1015 receives the control signal, it automatically switches from the first position to the second position.
  • the liquid enters the patient's body, for example into a vein, through the patient access.
  • the pressure measuring device 1013 records measured values. The measured values are a measure of the pressure on the pump inlet side, which is present inside the line, ie inside the tube 24 and the tube piece 28 between the pump 1011 and the liquid-retaining filter membrane 23 .
  • the pressure measuring device 113 can record the measured values continuously or intermittently.
  • the pump 1011 first delivers liquid through the hose 24.
  • the liquid level in the drip chamber 21 or in the hose 24 continues to fall. This happens until the liquid level has reached the liquid-retaining filter membrane 23, 23a.
  • the pressure of the liquid in the pump inlet-side area of the hose between the liquid-retaining filter membrane 23, 23a and the pump 1011 drops because the pump 1011 continues to suck from this area.
  • the drop in the pressure on the pump inlet side is recognized by the control device 1014 on the basis of the measured values recorded by the pressure measuring device 1013 .
  • the control device 1014 therefore detects a change in the pressure on the pump inlet side. Based on the change in the pressure on the pump inlet side, the control device 1014 also determines whether the delivery of the liquid from the first container 4 is to be ended. This is the case when the control device establishes that a criterion related to the change in pressure or to the measured values is met.
  • the criterion can be, for example: the pressure falls below a predetermined threshold value; Falling below a predetermined threshold value of the difference quotient of the pressure formed with time increments; Falling below a predetermined threshold value of the differential quotient formed by the time derivative of the pressure.
  • control device 1014 If the control device 1014 has determined that the conveying of the liquid from the first container 4 is to be ended, it generates a corresponding control signal.
  • This control signal causes the device 100 to switch the multi-way valve 1015 from the first position to the second position, so that another liquid is conveyed from a second container 4' to the patient connection.
  • the multi-way valve 1015 shuts off the tube 24 so that no air is pumped through the tube 24 .
  • the infusion or transfusion of the liquid from the first container 4 is automatically stopped and the infusion or transfusion of the liquid from the second container 4' is automatically started, saving the time of medical personnel when administering multiple infusions or transfusions consecutively to the same patient , ie the administration of a sequential infusion or transfusion, is greatly reduced.
  • the device according to the third embodiment has a multi-way valve 1015, which can be switched between a first position and a second position, so that the pumps 1011 sequentially liquid from the first container 4 and from the second container 4 'in the context of an automatic sequential infusion or Transfusion promotes to administer to the patient.
  • the device according to the invention has a multi-way valve with a corresponding number of ways.
  • An infusion or transfusion set with a corresponding number of tubes is used together with the device.
  • several multi-way valves can also be provided.
  • a fourth exemplary embodiment of the device 1100 according to the invention is shown in FIG. 5 .
  • the device 1100 has a second multi-way valve 1016.
  • the device 1100 according to the fourth exemplary embodiment is constructed analogously to the device 1000 according to the third exemplary embodiment.
  • the line can be branched again by the second multi-way valve 1016, so that another supply line (not shown in FIG.
  • the second multi-way valve 1016 can be switched from a first position to a second position on the basis of a control signal. In the first position the path for the liquid from the third container is closed. In the second position the path for the liquid from the third container is open. If the controller 1014 has determined that the funding of Liquid is to end from the second container 4, it generates a corresponding control signal. The control signal switches the second multi-way valve 101 from the first to the second position, so that another liquid is conveyed from the third container to the patient connection. At the same time, the second multi-way valve 1016 shuts off the path for three liquids from the second container 4', so that no air is pumped through the line. In this way, an automatic sequential infusion or transfusion of liquids from three containers can be implemented.
  • An automatic sequential infusion or transfusion of liquids from more than three containers can be implemented in an analogous manner. For this it is necessary to provide more than three multi-way valves or one multi-way valve which can be switched between a sufficient number of positions.
  • the control device 14, 114, 1014 of the device 1, 100, 1000, 1100 is set up to check whether the delivery of the liquid has ended and whether a communication signal to a data connection 31 between the device and a device 3, which is set up for reading in the communication signal, is to be output and/or whether the device 100, 1000, 1100 is to be prompted to convey another liquid from another container 4' to the patient.
  • the control device 14, 114, 1014 then checks whether the delivery of the liquid from the current container has ended and whether another liquid is to be taken from another container or a communication signal is to be output.
  • control device 14, 114, 1014 causes the pump 11, 111, 121, 1011, for example, to temporarily reverse the pumping direction, i.e. to pump in the direction away from the patient.
  • control device 14, 114, 1014 determines whether there is liquid on the side of the liquid-retaining filter membrane 23, 23', 23a, 23a' facing away from the pump 11, 111, 121, 1011.
  • a verification criterion can consist, for example, in determining whether the measured values recorded by the pressure measuring device 13, 113, 123, 1013 when the pumping direction is reversed, a pressure increase in the line between the pump 11, 111, 121, 1011 and the liquid-retaining filter membrane 23 , 23', 23a, 23a which is greater than a predetermined threshold. If this is the case, there is a malfunction in the liquid-retaining filter membrane 23, 23', 23a, 23a.
  • the liquid-retaining filter membrane 23, 23', 23a, 23a could be clogged.
  • the control device can react to this, for example, by causing the device 1, 100, 1000, 1010 to continue the infusion or transfusion from another container or to switch to the alarm state.
  • the infusion or transfusion set has at least one suitable non-return valve.

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  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Dispositif (1, 100, 1000, 1100) d'administration d'une perfusion ou transfusion d'un liquide issu d'un récipient 4, comprenant – une pompe (11, 111, 121, 1011) située au niveau du raccord patient et destinée au refoulement du liquide via une conduite (24, 24', 28) qui présente une membrane filtrante retenant le liquide (23, 23', 23a, 23a'), – un dispositif manométrique (13, 113, 123, 1013) destiné à la détection de valeurs de mesure correspondant à une pression côté alimentation de pompe, et – un dispositif de commande (14, 114, 1014). Le dispositif de commande (14, 114, 1014) est conçu pour identifier un changement de la pression côté entrée de pompe à l'aide des valeurs mesurées. Le dispositif de commande (14, 114, 1014) est également conçu pour déterminer la pression côté alimentation de la pompe, si l'acheminement du liquide doit se terminer. Le dispositif de commande (14, 114, 1014) est également conçu pour générer un signal de commande lorsque l'acheminement du liquide doit être terminé. Le dispositif de commande (14, 114, 1014) est également conçu pour émettre, sur la base du signal de commande, un signal de communication à une liaison de données (31) établie entre le dispositif (1) et un équipement (3) qui est conçu pour lire le signal de communication, émettre et/ou, sur la base du signal de commande, faire passer le dispositif (100, 1000, 1100) d'un premier mode de fonctionnement actif à un deuxième mode de fonctionnement actif.
EP21777985.9A 2020-09-15 2021-09-13 Dispositif d'administration d'une perfusion ou transfusion, système comprenant un tel dispositif et procédé de commande d'un tel dispositif Pending EP4213912A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102020211555.9A DE102020211555A1 (de) 2020-09-15 2020-09-15 Vorrichtung zur Verabreichung einer Infusion oder Transfusion, System umfassend eine derartige Vorrichtung und Verfahren zum Steuern einer derartigen Vorrichtung
PCT/EP2021/075081 WO2022058275A1 (fr) 2020-09-15 2021-09-13 Dispositif d'administration d'une perfusion ou transfusion, système comprenant un tel dispositif et procédé de commande d'un tel dispositif

Publications (1)

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EP4213912A1 true EP4213912A1 (fr) 2023-07-26

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EP21777985.9A Pending EP4213912A1 (fr) 2020-09-15 2021-09-13 Dispositif d'administration d'une perfusion ou transfusion, système comprenant un tel dispositif et procédé de commande d'un tel dispositif

Country Status (4)

Country Link
US (1) US20240024569A1 (fr)
EP (1) EP4213912A1 (fr)
DE (1) DE102020211555A1 (fr)
WO (1) WO2022058275A1 (fr)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855122B1 (en) * 1999-02-10 2005-02-15 Tomio Ohta Bloodless treating device
EP1181065B1 (fr) 1999-05-03 2003-07-30 BD Infusion Therapy GmbH Infuseur
US7092796B2 (en) 2003-11-14 2006-08-15 Cardinal Health 303, Inc. System and method for verifying connection of correct fluid supply to an infusion pump
US7206715B2 (en) * 2003-12-31 2007-04-17 Cardinal Health 303, Inc. Empty container detection using container side pressure sensing
CN102114279A (zh) 2009-12-31 2011-07-06 北京谊安医疗系统股份有限公司 一种输液泵
US9662444B2 (en) * 2014-06-19 2017-05-30 Carefusion 303, Inc. Empty infusion supply container annunciator and detection method
US20160213862A1 (en) * 2015-01-27 2016-07-28 Becton, Dickinson And Company Iv set having an air stop membrane

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DE102020211555A1 (de) 2022-03-17
WO2022058275A1 (fr) 2022-03-24
US20240024569A1 (en) 2024-01-25

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