EP4134369A1 - Formes solides de composés tétrahydropyranyl amino-pyrrolopyrimidinone - Google Patents
Formes solides de composés tétrahydropyranyl amino-pyrrolopyrimidinone Download PDFInfo
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- EP4134369A1 EP4134369A1 EP22193074.6A EP22193074A EP4134369A1 EP 4134369 A1 EP4134369 A1 EP 4134369A1 EP 22193074 A EP22193074 A EP 22193074A EP 4134369 A1 EP4134369 A1 EP 4134369A1
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- Prior art keywords
- approximately
- compound
- sets forth
- polymorph
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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| US201862718318P | 2018-08-13 | 2018-08-13 | |
| EP19759241.3A EP3837260A1 (fr) | 2018-08-13 | 2019-08-13 | Formes solides de composés tétrahydropyranyl-amino-pyrrolopyrimidinone |
| PCT/US2019/046269 WO2020036913A1 (fr) | 2018-08-13 | 2019-08-13 | Formes solides de composés tétrahydropyranyl-amino-pyrrolopyrimidinone |
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| EP19759241.3A Division EP3837260A1 (fr) | 2018-08-13 | 2019-08-13 | Formes solides de composés tétrahydropyranyl-amino-pyrrolopyrimidinone |
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| EP4134369A1 true EP4134369A1 (fr) | 2023-02-15 |
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| EP22193074.6A Pending EP4134369A1 (fr) | 2018-08-13 | 2019-08-13 | Formes solides de composés tétrahydropyranyl amino-pyrrolopyrimidinone |
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| US (1) | US10975087B2 (fr) |
| EP (2) | EP3837260A1 (fr) |
| TW (1) | TWI820182B (fr) |
| WO (1) | WO2020036913A1 (fr) |
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| JP2024518790A (ja) * | 2021-05-12 | 2024-05-02 | ジャージアン・ロングチャーム・バイオ－テック・ファーマ・カンパニー・リミテッド | ピロロピリミジン類化合物の結晶形およびその調製方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US9630968B1 (en) | 2015-12-23 | 2017-04-25 | Arqule, Inc. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
| WO2018039310A1 (fr) * | 2016-08-24 | 2018-03-01 | Arqule, Inc. | Composés amino-pyrrolopyrimidinone et leurs procédés d'utilisation |
-
2019
- 2019-08-13 TW TW108128744A patent/TWI820182B/zh active
- 2019-08-13 US US16/538,957 patent/US10975087B2/en active Active
- 2019-08-13 WO PCT/US2019/046269 patent/WO2020036913A1/fr unknown
- 2019-08-13 EP EP19759241.3A patent/EP3837260A1/fr not_active Withdrawn
- 2019-08-13 EP EP22193074.6A patent/EP4134369A1/fr active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US9630968B1 (en) | 2015-12-23 | 2017-04-25 | Arqule, Inc. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
| WO2018039310A1 (fr) * | 2016-08-24 | 2018-03-01 | Arqule, Inc. | Composés amino-pyrrolopyrimidinone et leurs procédés d'utilisation |
Non-Patent Citations (12)
| Title |
|---|
| "Remington: the Science and Practice of Pharmacy", 1995, MACK PUBLISHING CO |
| "Remington's Pharmaceutical Sciences", 1990, MACK PUBLISHING CO. |
| AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 2005, JOHN WILEY AND SONS, INC |
| BUNDEGAARD, H.: "Design of Prodrugs", 1985, ELSEVIER, pages: l-92 |
| COLIGAN ET AL.: "The Pharmacological Basis of Therapeutics", 1975, JOHN WILEY & SONS |
| DIPAOLO, NATURE CHEM. BIOL., vol. 7, no. 1, 2011, pages 41 - 50 |
| E. L. ELIELS. H. WILENL. N. MANDER: "Stereochemistry of Organic Compounds", 1994, WILEY-LNTERSCIENCE |
| GREENE, T.W.WUTS, P.G: "M. Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS |
| HUNTER, CELL, vol. 50, 1987, pages 823 - 829 |
| LIU, JOUR. PHARMACOL. EXP. THER., vol. 338, no. 1, 2011, pages 154 - 163 |
| SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 2000, COLD SPRING HARBOR PRESS |
| SMITH, M.BMARCH, J: "March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure", 2001, JOHN WILEY & SONS |
Also Published As
| Publication number | Publication date |
|---|---|
| US20200140442A1 (en) | 2020-05-07 |
| US10975087B2 (en) | 2021-04-13 |
| TWI820182B (zh) | 2023-11-01 |
| TW202024087A (zh) | 2020-07-01 |
| EP3837260A1 (fr) | 2021-06-23 |
| WO2020036913A1 (fr) | 2020-02-20 |
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