EP4111208A4 - Système de surveillance en temps réel d'une protéine et d'excipients - Google Patents

Système de surveillance en temps réel d'une protéine et d'excipients

Info

Publication number
EP4111208A4
EP4111208A4 EP21760637.5A EP21760637A EP4111208A4 EP 4111208 A4 EP4111208 A4 EP 4111208A4 EP 21760637 A EP21760637 A EP 21760637A EP 4111208 A4 EP4111208 A4 EP 4111208A4
Authority
EP
European Patent Office
Prior art keywords
excipients
protein
real
time monitoring
monitoring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21760637.5A
Other languages
German (de)
English (en)
Other versions
EP4111208A1 (fr
Inventor
Anurag Rathore
Vishwanath Hebbi
Garima Thakur
Tushar Savane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indian Institute of Technology Delhi
Original Assignee
Indian Institute of Technology Delhi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indian Institute of Technology Delhi filed Critical Indian Institute of Technology Delhi
Publication of EP4111208A1 publication Critical patent/EP4111208A1/fr
Publication of EP4111208A4 publication Critical patent/EP4111208A4/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3577—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/85—Investigating moving fluids or granular solids
    • G01N21/8507—Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N2021/3595—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using FTIR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N2021/8411—Application to online plant, process monitoring
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/85—Investigating moving fluids or granular solids
    • G01N21/8507—Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • G01N2021/8528—Immerged light conductor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
EP21760637.5A 2020-02-24 2021-02-24 Système de surveillance en temps réel d'une protéine et d'excipients Pending EP4111208A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN202011007820 2020-02-24
PCT/IN2021/050176 WO2021171310A1 (fr) 2020-02-24 2021-02-24 Système de surveillance en temps réel d'une protéine et d'excipients

Publications (2)

Publication Number Publication Date
EP4111208A1 EP4111208A1 (fr) 2023-01-04
EP4111208A4 true EP4111208A4 (fr) 2024-04-10

Family

ID=77491253

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21760637.5A Pending EP4111208A4 (fr) 2020-02-24 2021-02-24 Système de surveillance en temps réel d'une protéine et d'excipients

Country Status (2)

Country Link
EP (1) EP4111208A4 (fr)
WO (1) WO2021171310A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020155541A1 (en) * 1999-07-16 2002-10-24 Human Genome Sciences, Inc. Method and system for providing real-time, in situ biomanufacturing process monitoring and control in response to IR spectroscopy
US20120123688A1 (en) * 2010-09-17 2012-05-17 Abbott Laboratories Raman spectroscopy for bioprocess operations
WO2017051273A1 (fr) * 2015-09-22 2017-03-30 Pfizer Inc. Procédé de préparation d'une formulation de protéine thérapeutique et formulation d'anticorps produite par un tel procédé
WO2017174580A1 (fr) * 2016-04-04 2017-10-12 Boehringer Ingelheim Rcv Gmbh & Co Kg Surveillance en temps réel de purification de produit
WO2020016417A1 (fr) * 2018-07-19 2020-01-23 Ichnos Sciences S.A. Formulation d'anticorps liquide

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020155541A1 (en) * 1999-07-16 2002-10-24 Human Genome Sciences, Inc. Method and system for providing real-time, in situ biomanufacturing process monitoring and control in response to IR spectroscopy
US20120123688A1 (en) * 2010-09-17 2012-05-17 Abbott Laboratories Raman spectroscopy for bioprocess operations
WO2017051273A1 (fr) * 2015-09-22 2017-03-30 Pfizer Inc. Procédé de préparation d'une formulation de protéine thérapeutique et formulation d'anticorps produite par un tel procédé
WO2017174580A1 (fr) * 2016-04-04 2017-10-12 Boehringer Ingelheim Rcv Gmbh & Co Kg Surveillance en temps réel de purification de produit
WO2020016417A1 (fr) * 2018-07-19 2020-01-23 Ichnos Sciences S.A. Formulation d'anticorps liquide

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANIRUDH M K NAMBIAR ET AL: "Countercurrent staged diafiltration for formulation of high value proteins", BIOTECHNOLOGY AND BIOENGINEERING, JOHN WILEY, HOBOKEN, USA, vol. 115, no. 1, 6 October 2017 (2017-10-06), pages 139 - 144, XP071153567, ISSN: 0006-3592, DOI: 10.1002/BIT.26441 *
See also references of WO2021171310A1 *

Also Published As

Publication number Publication date
EP4111208A1 (fr) 2023-01-04
WO2021171310A1 (fr) 2021-09-02

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