EP4093844C0 - Bioreactor for cultivating cells - Google Patents

Bioreactor for cultivating cells

Info

Publication number
EP4093844C0
EP4093844C0 EP21701966.0A EP21701966A EP4093844C0 EP 4093844 C0 EP4093844 C0 EP 4093844C0 EP 21701966 A EP21701966 A EP 21701966A EP 4093844 C0 EP4093844 C0 EP 4093844C0
Authority
EP
European Patent Office
Prior art keywords
bioreactor
cultivating cells
cultivating
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP21701966.0A
Other languages
German (de)
French (fr)
Other versions
EP4093844A1 (en
EP4093844B1 (en
Inventor
Simon Vogel
Stefan Schillberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Original Assignee
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV filed Critical Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Publication of EP4093844A1 publication Critical patent/EP4093844A1/en
Application granted granted Critical
Publication of EP4093844C0 publication Critical patent/EP4093844C0/en
Publication of EP4093844B1 publication Critical patent/EP4093844B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP21701966.0A 2020-01-23 2021-01-23 Bioreactor for cultivating cells Active EP4093844B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20153266.0A EP3854867A1 (en) 2020-01-23 2020-01-23 Method for culturing prokaryotic and eukaryotic cells in a structured matrix under physical stress
PCT/EP2021/051538 WO2021148663A1 (en) 2020-01-23 2021-01-23 Bioreactor for the cultivation of cells

Publications (3)

Publication Number Publication Date
EP4093844A1 EP4093844A1 (en) 2022-11-30
EP4093844C0 true EP4093844C0 (en) 2024-04-17
EP4093844B1 EP4093844B1 (en) 2024-04-17

Family

ID=69191871

Family Applications (2)

Application Number Title Priority Date Filing Date
EP20153266.0A Withdrawn EP3854867A1 (en) 2020-01-23 2020-01-23 Method for culturing prokaryotic and eukaryotic cells in a structured matrix under physical stress
EP21701966.0A Active EP4093844B1 (en) 2020-01-23 2021-01-23 Bioreactor for cultivating cells

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP20153266.0A Withdrawn EP3854867A1 (en) 2020-01-23 2020-01-23 Method for culturing prokaryotic and eukaryotic cells in a structured matrix under physical stress

Country Status (6)

Country Link
US (1) US20230050194A1 (en)
EP (2) EP3854867A1 (en)
CN (1) CN114901795A (en)
CA (1) CA3165617A1 (en)
IL (1) IL294969A (en)
WO (1) WO2021148663A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409854B2 (en) 2001-07-31 2013-04-02 Sartorius Stedim Biotech Gmbh Bioreactor provided with equipment with flexible walls
DE10322024A1 (en) * 2003-05-16 2004-12-02 Symetis Ag Bioreactor for manufacturing a tissue prosthesis, in particular a heart valve
CA2801768A1 (en) * 2013-01-09 2014-07-09 Soheyl S. M. Mottahedeh A photobioreactor bag with built-in sparger tube, agitator and water
US20150252317A1 (en) * 2014-03-10 2015-09-10 Flodesign Sonics, Inc. Disposable bioreactor with filtration system

Also Published As

Publication number Publication date
EP3854867A1 (en) 2021-07-28
CA3165617A1 (en) 2021-07-29
EP4093844A1 (en) 2022-11-30
WO2021148663A1 (en) 2021-07-29
US20230050194A1 (en) 2023-02-16
EP4093844B1 (en) 2024-04-17
IL294969A (en) 2022-09-01
CN114901795A (en) 2022-08-12

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