EP4076165A1 - Dispositif de mesure continue et non invasive de la tension artérielle - Google Patents

Dispositif de mesure continue et non invasive de la tension artérielle

Info

Publication number
EP4076165A1
EP4076165A1 EP20829138.5A EP20829138A EP4076165A1 EP 4076165 A1 EP4076165 A1 EP 4076165A1 EP 20829138 A EP20829138 A EP 20829138A EP 4076165 A1 EP4076165 A1 EP 4076165A1
Authority
EP
European Patent Office
Prior art keywords
blood pressure
brachial
patient
sensor
waveform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20829138.5A
Other languages
German (de)
English (en)
Inventor
Blake W. Axelrod
Alexander H. Siemons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edwards Lifesciences Corp
Original Assignee
Edwards Lifesciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Edwards Lifesciences Corp filed Critical Edwards Lifesciences Corp
Publication of EP4076165A1 publication Critical patent/EP4076165A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers using the oscillometric method
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6824—Arm or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6831—Straps, bands or harnesses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7278—Artificial waveform generation or derivation, e.g. synthesising signals from measured signals

Definitions

  • Embodiments of the invention relate to non-invasive blood pressure measurement. More particularly, embodiments relate to an external brachial arm cuff and a sensor that combine discrete absolute blood pressure measurements with a measured continuous pulsatility waveform for pulse wave analysis (PWA) blood pressure (BP) tracking to provide continuous beat-to-beat non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP blood pressure
  • PWA Pulse wave analysis
  • a blood pressure measurement device to measure a patient’s blood pressure from a patient’s arm.
  • the blood pressure measurement device may comprise: an external brachial arm cuff mountable around the patient’s arm to determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery; and a sensor mountable near the external brachial arm cuff to measure a continuous pulsatility waveform from the patient’s brachial artery.
  • the discrete absolute blood pressure measurements may be combined with the measured continuous pulsatility waveform for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at the brachial location to provide continuous beat-to-beat non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • the senor may be a flexible pressure sensor to measure artery pulsations by surface pressure induced by the movement of the patient’s brachial artery.
  • the sensor may be a strain sensor to measure artery pulsations by strains induced by the movement of the patient’s brachial artery.
  • the external brachial arm cuff may be an oscillometric cuff.
  • the absolute blood pressure measurements comprise systolic pressure, mean arterial pressure (MAP), and diastolic pressure.
  • the brachial location may be at approximately heart level, such that, compensation for hydrostatic changes is not required.
  • the continuous non-invasive blood pressure monitoring is displayed on a display device. It should be appreciated that the optional examples may be utilized independently from one another or in combination with one another.
  • Figure 1 is a diagram of a blood pressure measurement device to measure a patient’s blood pressure from a patient’s arm, according to one example.
  • Figure 2 is a view of blood pressure measurement device attached to a patient’s arm to measure the patient’s blood pressure from the patient’s arm, according to one example.
  • Figure 3 is a flowchart illustrating a method for continuously monitoring the blood pressure of a patient, according to one example.
  • Figure 4 is a graph of a waveform illustrating a continuous pulsatility waveform of the patient’s brachial artery, according to one example.
  • Figure 5 is a graph showing discrete absolute blood pressure measurements combined with the obtained pulsatility waveform for pulse wave analysis (PWA) blood pressure (BP) tracking to provide for continuous beat-to-beat non-invasive blood pressure monitoring, according to one example.
  • PWA pulse wave analysis
  • BP blood pressure
  • Examples of the disclosure may relate to: combining a sensor to obtain pulsatility waveforms for pulse wave analysis (PWA) blood pressure (BP) tracking at a brachial location with a traditional oscillometric brachial arm cuff.
  • PWA pulse wave analysis
  • BP blood pressure
  • This is beneficial in that it may combine both absolute blood pressure measurement and tracking into a single device.
  • this type of implementation of combining a traditional oscillometric brachial arm cuff with a sensor provides a type of form factor that is well understood and accepted in suitable medical environments (e.g., hospitals and other healthcare settings).
  • the brachial location is at heart level and does not require compensation for hydrostatic changes.
  • examples of the disclosure relate to combining a sensor (e.g., a flexible pressure sensor or strain sensor) to obtain a pulsatility waveform from which changes in blood pressure (BP) may be tracked using PWA (Pulse Wave Analysis) techniques with a traditional external oscillometric brachial arm cuff that measures a discrete absolute blood pressure measurement from which the changes can be tracked.
  • a sensor e.g., a flexible pressure sensor or strain sensor
  • PWA Pulse Wave Analysis
  • a diagram of a blood pressure measurement device 100 to measure a patient’s blood pressure from a patient’s arm is disclosed.
  • the blood pressure measurement device 100 may comprise: an external brachial arm cuff 102 mountable around the patient’s arm to determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery; and a sensor 104 mountable near the external brachial arm cuff to measure a continuous pulsatility waveform from the patient’s brachial artery.
  • BP blood pressure
  • the discrete absolute blood pressure measurements may be combined with the measured continuous pulsatility waveform from the sensor 104 for pulse wave analysis (PWA) blood pressure (BP) beat-to-beat tracking at the brachial location to provide continuous beat-to-beat non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP blood pressure
  • the blood pressure measurement device 100 may include the external brachial arm cuff 102 mountable around a patient’s arm; the sensor 104 mountable near the external brachial arm cuff; a display device 120; a memory 107; and a processor 106 coupled to the memory 107.
  • the processor may process data to: determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery from the external brachial arm cuff 102; measure a continuous pulsatility waveform from the patient’s brachial artery from the sensor 104; combine the discrete absolute blood pressure measurements with the measured continuous pulsatility waveform for pulse wave analysis (PWA) blood pressure (BP) tracking at the brachial location to determine continuous beat-to- beat non-invasive blood pressure values; and display the continuous beat-to-beat non- invasive blood pressure values on the display device 120.
  • PWA pulse wave analysis
  • BP blood pressure
  • a wireless or wired interface 108 may transmit the continuous beat-to-beat non-invasive blood pressure values for display on the display device 120. Therefore, continuous non-invasive blood pressure monitoring may be displayed on the display device 120.
  • the sensor 104 may be a flexible pressure sensor to measure artery pulsations by surface pressure on the patient’s skin induced by the movement of the patient’s brachial artery.
  • the sensor 104 may be a strain sensor to measure artery pulsations by strains induced by the movement of the patient’s brachial artery on the patient’s skin.
  • the external brachial arm cuff 102 may be an oscillometric cuff.
  • the external brachial arm cuff 102 may be an auscultatory cuff.
  • the absolute blood pressure measurements may comprise systolic pressure, mean arterial pressure (MAP), and diastolic pressure.
  • the brachial location where the cuffs and sensor are located may be at approximately heart level, such that, compensation for hydrostatic changes is not required.
  • the continuous non-invasive blood pressure monitoring may be displayed on a display device 120.
  • the blood pressure measurement device 100 may comprise: an external brachial arm cuff 102 mountable around the patient’s arm 130 to determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery 140; and a sensor 104 mountable near the external brachial arm cuff 102 to measure a continuous pulsatility waveform from the patient’s brachial artery.
  • the discrete absolute blood pressure measurements may be combined with the measured continuous pulsatility waveform for pulse wave analysis (PWA) blood pressure (BP) beat-to-beat tracking at the brachial location to provide continuous non- invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP blood pressure
  • the external brachial arm cuff 102 may be placed around a patient’s upper arm 132.
  • the external brachial arm cuff 102 may be of conventional shape - approximately circular and conical shaped with a cavity to accept the patient’s arm 130.
  • the external brachial arm cuff 102 may comprise components necessary for conventional oscillometric blood pressure measurement (e.g., pneumatic elements, pressure sensors, etc.). Arm cuffs to perform oscillometric blood pressure measurement are well known in the art.
  • the external brachial arm cuff 102 may be an auscultatory cuff.
  • the external brachial arm cuff 102 may be wrapped around the patient’s upper arm 132.
  • the external brachial oscillometric arm cuff 102 may be used to measure discrete absolute blood pressure from the brachial artery 140 (e.g., systolic pressure, diastolic pressure, mean arterial pressure (MAP), etc.).
  • a sensor 104 may be mounted on the patient’s inner arm 134.
  • the sensor 104 may be a flexible pressure sensor or a strain sensor.
  • the flexible pressure sensor 104 or strain sensor 104 may be used to obtain a pulsatility waveform from the brachial artery 140.
  • the sensor 104 may conform to the subject’s inner arm 134 in close proximity to the brachial artery 140.
  • the sensor 104 can measure the pulsations of the brachial artery 140.
  • the flexible pressure sensor 104 may measure the surface pressure of the inner arm 134 by the movement of the brachial artery 140.
  • the strain sensor 104 may measure strains induced by the movement of the brachial artery 140 within the inner arm 134.
  • the flexible pressure sensor or strain sensor may measure a continuous pulsatility waveform.
  • the discrete absolute blood pressure measurements from the external brachial arm cuff 102 can be combined with the obtained pulsatility waveforms from the sensor 104 for pulse wave analysis (PWA) blood pressure (BP) tracking at the brachial location to provide for continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP blood pressure
  • the brachial location may be at approximately heart level 145, such that, compensation for hydrostatic changes is not required.
  • a flexible pressure sensor or a strain sensor are provided as examples of a sensor 104 that may be utilized, it should be appreciated that any suitable digital or analog sensor may be utilized to perform the previously described functions.
  • any suitable type of electronic pressure sensor, electromagnetic pressure sensor, mechanical pressure sensor, capacitive pressure sensor, optical pressure sensor, piezoelectric pressure sensor, strain gauge pressure sensor, piezoresistive strain gauge pressure sensor, etc. may be utilized, which are merely examples. Therefore, it should be appreciated that the optional examples (e.g., flexible pressure sensors, strain sensors, or other types of sensors) may be utilized independently from one another or in combination with one another.
  • sensor 104 may be coupled to the external brachial arm cuff 102 by connection wires 150 such that the arm cuff and sensor are connectable to a patient in a suitable easy way with a proper form factor to be simply connectable to a patient by medical personnel in a medical environment or by any user (e.g., a personal home user).
  • blood pressure measurement device 100 that includes both the arm cuff 102 and sensor 104 is an easily useable product.
  • this is only one example of a connection type between the arm cuff 102 and sensor 104.
  • the arm cuff 102 and sensor 104 may be connectable by any suitable means, such as, flexible polymers (natural or synthetic), plastics, metals, combinations thereof, VELCRO, adhesive, mechanical methods, etc., or any suitable means to keep the arm cuff 102 and sensor 104 connected together.
  • the arm cuff 102 and sensor 104 may each be separately connected to the patient’s arm 130 and not physically connected each other.
  • the sensor 104 and arm cuff 102 may be wirelessly connected by suitable electromagnetic signal transmission means to one another and/or other local or remote computing devices for the processing of obtained pulsatility waveforms from the sensor 104 for pulse wave analysis (PWA) blood pressure (BP) tracking at the brachial location to provide for continuous non- invasive blood pressure monitoring, as will be described in more detail hereafter. Therefore, it should be appreciated that optional examples may be utilized independently from one another or in combination with one another.
  • PWA pulse wave analysis
  • BP blood pressure
  • Figure 3 is a flowchart illustrating an optional example method 300.
  • a method for continuously monitoring the blood pressure of a patient is shown.
  • discrete absolute blood pressure (BP) measurements are determined from the patient’s brachial artery from an external brachial arm cuff.
  • a continuous pulsatility waveform from the patient’s brachial artery from a sensor is measured.
  • the discrete absolute blood pressure measurements are combined with the measured continuous pulsatility waveform for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at the brachial location to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • FIG. 4 shows a graph of a waveform 400 (pulsatility versus time) illustrating the continuous pulsatility waveform of the patient’s brachial artery 140 as measured by the sensor 104.
  • Figure 5 shows the discrete absolute blood pressure measurements combined with the obtained pulsatility waveforms for pulse wave analysis (PWA) blood pressure (BP) tracking to provide for continuous non-invasive blood pressure monitoring.
  • Figure 5 illustrates blood pressure values versus time.
  • 501 shows discrete absolute blood pressure measurements 510 (e.g., systolic) from the external arm cuff 102 combined with the obtained continuous pulsatility waveform 400 from the sensor 104 that undergoes pulse wave analysis (PWA) blood pressure (BP) tracking to create beat-to-beat blood pressure values 500 to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP blood pressure
  • the intervals between the systolic discrete absolute blood pressure measurements 510 are calculated based upon the combination of the discrete systolic absolute blood pressure measurements 510 with the measured continuous pulsatility waveform 400 that provides for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking to provide for the continuous beat-to-beat non-invasive blood pressure values 500 (e.g., including the intervals between the discrete absolute blood pressure measurements).
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • 503 shows discrete absolute blood pressure measurements 520 (e.g., diastolic) from the external arm cuff 102 combined with the obtained continuous pulsatility waveform 400 from the sensor 104 that undergoes pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking to create beat-to-beat blood pressure values 502 to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • the intervals between the diastolic discrete absolute blood pressure measurements 520 are calculated based upon the combination of the discrete diastolic absolute blood pressure measurements 520 with the measured continuous pulsatility waveform 400 that provides for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking to provide for the continuous beat-to-beat non-invasive blood pressure values 502 (e.g., including the intervals between the discrete absolute blood pressure measurements).
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • MAP mean arterial pressure
  • the blood pressure measurement device 100 may comprise: an external brachial arm cuff 102 mountable around the patient’s arm 130 to determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery 140; and a sensor 104 mountable near the external brachial arm cuff 102 to measure a continuous pulsatility waveform (e.g., the measured continuous pulsatility waveform 400 from Figure 4) from the patient’s brachial artery.
  • BP blood pressure
  • the discrete absolute blood pressure measurements may be combined with the measured continuous pulsatility waveform (e.g., the measured continuous pulsatility waveform 400 from Figure 4) to provide for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at the brachial location to provide continuous non-invasive blood pressure monitoring (e.g., including the intervals between the discrete absolute blood pressure measurements).
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • 501 shows discrete absolute blood pressure measurements 510 (e.g., systolic) from the external arm cuff 102 combined with the obtained continuous pulsatility waveform 400 from the sensor 104 that undergoes pulse wave analysis (PWA) blood pressure (BP) tracking to create beat-to-beat blood pressure values 500 to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP blood pressure
  • 503 shows discrete absolute blood pressure measurements 520 (e.g., diastolic) from the external arm cuff 102 combined with the obtained continuous pulsatility waveform 400 from the sensor 104 that undergoes pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking to create beat-to-beat blood pressure values 502 to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • PWA pulse wave analysis
  • This continuous non-invasive blood pressure monitoring may be displayed on an appropriate display device 120.
  • the blood pressure measurement device 100 may include the external brachial arm cuff 102 mountable around a patient’s arm 130; the sensor 104 mountable near the external brachial arm cuff 102; a display device 102; a memory 107; and a processor 106 coupled to the memory 107.
  • the processor may process data to: determine discrete absolute blood pressure (BP) measurements (e.g., 510, 520 from Figure 5) from the patient’s brachial artery 140 from the external brachial arm cuff 102; measure a continuous pulsatility waveform (e.g., 400 from Figure 4) from the patient’s brachial artery 140 from the sensor 104; combine the discrete absolute blood pressure measurements with the measured continuous pulsatility waveform for pulse wave analysis (PWA) blood pressure (BP) tracking at the brachial location to determine a continuous non-invasive blood pressure waveform (e.g., a waveform implementation that is similar to the values shown in Figure 5); and display the continuous non-invasive blood pressure waveforms on the display device 120.
  • BP discrete absolute blood pressure
  • PWA pulse wave analysis
  • BP blood pressure
  • the discrete absolute blood pressure measurements may be combined with the measured continuous pulsatility waveform (e.g., measured continuous pulsatility waveform 400 from Figure 4) for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at the brachial location to provide continuous non-invasive blood pressure monitoring (e.g., including the intervals between the discrete absolute blood pressure measurements).
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • beat-to-beat values 500 shows discrete absolute blood pressure measurements 510 (e.g., systolic) from the external arm cuff 102 combined with the obtained continuous pulsatility waveform 400 from the sensor 104 that undergoes pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking to create beat-to-beat values 500 to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • beat-to-beat values 502 shows discrete absolute blood pressure measurements 520 (e.g., diastolic) from the external arm cuff 102 combined with the obtained continuous pulsatility waveform 400 from the sensor 104 that undergoes pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking to create beat-to-beat values 502 to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • a variety of pulse wave analysis (PWA) techniques may be utilized to achieve these functions.
  • the patient’s blood pressure can be continuously monitored, tracked, determined, and displayed based on the discrete baseline absolute blood pressures and the pulsatility waveform utilizing PWA techniques.
  • Such PWA techniques may include any suitable PWA technique, such as techniques developed by Centre Canal d’Electronique et de Microtechnique (CSEM). This continuous non-invasive blood pressure monitoring may be displayed on an appropriate display device 120.
  • CSEM Circuit Engineering et de Microtechnique
  • processing functions to implement PWA blood pressure tracking to implement the continuous non-invasive blood pressure monitoring for calculation and display may be implemented utilizing appropriate hardware, firmware, and/or software at the arm cuff 102, sensor 104, display device 120, or by any suitable local or remote computing device, or combinations thereof, and these devices may be in suitable wired and/or wireless communication.
  • the display on the display device may be a local display at the device itself, at a local remote device, or at a remote device at any location.
  • the disclosure relates to combining a flexible pressure sensor or strain sensor to obtain a pulsatility waveform from which changes in blood pressure (BP) may be tracked using PWA (Pulse Wave Analysis) techniques with an external cuff that measures a discrete absolute blood pressure measurement from which changes can be tracked.
  • examples of the disclosure may relate to: combining a sensor to obtain pulsatility waveforms for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at a brachial location with a traditional oscillometric brachial arm cuff. This is beneficial in that it may combine both absolute blood pressure measurement and tracking into a single device.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • this type of implementation of combining a traditional oscillometric brachial arm cuff with a sensor provides a type of form factor that is well understood and accepted in suitable medical environments (e.g., hospitals and other healthcare settings). However, implementations may also be easily implemented in non-medical environments (e.g., home, work, etc.).
  • processors may operate under the control of a program, algorithm, routine, or the execution of instructions to execute methods or processes (e.g., method 300 of Figure 3) in accordance with embodiments previously described.
  • a program may be implemented in firmware or software (e.g. stored in memory and/or other locations) and may be implemented by processors, control circuitry, and/or other circuitry, these terms being utilized interchangeably.
  • processor microprocessor, circuitry, control circuitry, circuit board, controller, microcontroller, etc.
  • processor microprocessor, circuitry, control circuitry, circuit board, controller, microcontroller, etc.
  • processor microprocessor, circuitry, control circuitry, circuit board, controller, microcontroller, etc.
  • processors, modules, and circuitry described in connection with the embodiments disclosed herein may be implemented or performed with a general purpose processor, a specialized processor, circuitry, a microcontroller, a digital signal processor (DSP), an application specific integrated circuit (ASIC), a field programmable gate array (FPGA) or other programmable logic device, discrete gate or transistor logic, discrete hardware components, or any combination thereof designed to perform the functions described herein.
  • a processor may be a microprocessor or any conventional processor, controller, microcontroller, circuitry, or state machine.
  • a processor may also be implemented as a combination of computing devices, e.g., a combination of a DSP and a microprocessor, a plurality of microprocessors, one or more microprocessors in conjunction with a DSP core, or any other such configuration.
  • a software module may reside in RAM memory, flash memory, ROM memory, EPROM memory, EEPROM memory, registers, hard disk, a removable disk, a CD-ROM, or any other form of storage medium known in the art.
  • An exemplary storage medium is coupled to the processor such the processor can read information from, and write information to, the storage medium. In the alternative, the storage medium may be integral to the processor.
  • a blood pressure measurement device to measure a patient’s blood pressure from a patient’s arm, comprising: an external brachial arm cuff mountable around the patient’ s arm to determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery; and a sensor mountable near the external brachial arm cuff to measure a continuous pulsatility waveform from the patient’s brachial artery, wherein, the discrete absolute blood pressure measurements are combined with the measured continuous pulsatility waveform for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at the brachial location to provide continuous non-invasive blood pressure monitoring.
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • BP blood pressure
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • the blood pressure measurement device of claim 8 wherein the continuous blood pressure waveform is displayed on a display device.
  • a blood pressure measurement system comprising: an external brachial arm cuff mountable around a patient’ s arm; a sensor mountable near the external brachial arm cuff; a display device; a memory; and a processor coupled to the memory, the processor configured to: determine discrete absolute blood pressure (BP) measurements from the patient’s brachial artery from the external brachial arm cuff; measure a continuous pulsatility waveform from the patient’s brachial artery from the sensor; combine the discrete absolute blood pressure measurements with the measured continuous pulsatility waveform for pulse wave analysis (PWA) blood pressure (BP) tracking at the brachial location to determine a continuous non-invasive blood pressure waveform; and display the continuous non-invasive blood pressure waveform on the display device.
  • PWA pulse wave analysis
  • BP blood pressure
  • the blood pressure measurement system of claim 10 wherein the sensor is a strain sensor to measure artery pulsations by strains induced by the movement of the patient’ s brachial artery.
  • the external brachial arm cuff is an oscillometric cuff.
  • BP discrete blood pressure
  • PWA pulse wave analysis
  • BP beat-to-beat blood pressure
  • a method for continuously monitoring the blood pressure of a patient comprising: determining discrete absolute blood pressure (BP) measurements from the patient’s brachial artery from an external brachial arm cuff; measuring a continuous pulsatility waveform from the patient’s brachial artery from a sensor; and combining the discrete absolute blood pressure measurements with the measured continuous pulsatility waveform for pulse wave analysis (PWA) beat-to-beat blood pressure (BP) tracking at the brachial location to provide continuous non-invasive blood pressure monitoring.
  • BP pulse wave analysis
  • BP beat-to-beat blood pressure
  • the sensor is a flexible pressure sensor to measure artery pulsations by surface pressure induced by the movement of the patient’s brachial artery.
  • the sensor is a strain sensor to measure artery pulsations by strains induced by the movement of the patient’s brachial artery.
  • the external brachial arm cuff is an oscillometric cuff.
  • brachial location is at approximately heart level, such that, compensation for hydrostatic changes is not required.

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  • Animal Behavior & Ethology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
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  • Signal Processing (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne un dispositif de mesure de la tension artérielle pour mesurer la tension artérielle d'un patient à partir du bras d'un patient. Le dispositif de mesure de la tension artérielle peut comprendre un brassard brachial externe pouvant être monté autour du bras du patient pour déterminer des mesures de la tension artérielle absolue discrètes à partir de l'artère brachiale du patient, et un capteur pouvant être monté à proximité du brassard brachial externe pour mesurer une forme d'onde de pulsatilité continue à partir de l'artère brachiale du patient. Les mesures de la tension artérielle absolue discrètes sont combinées à la forme d'onde de pulsatilité continue mesurée pour un suivi de la tension artérielle (BP) battement à battement par une analyse d'onde pulsée (PWA) au niveau de l'emplacement brachial pour fournir une surveillance continue et non-invasive de la tension artérielle de battement à battement.
EP20829138.5A 2019-12-16 2020-12-09 Dispositif de mesure continue et non invasive de la tension artérielle Pending EP4076165A1 (fr)

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