EP4021690A4 - Detergent-free simultaneous multiomics sample preparation method using novel new vesicle design - Google Patents

Detergent-free simultaneous multiomics sample preparation method using novel new vesicle design Download PDF

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Publication number
EP4021690A4
EP4021690A4 EP20859077.8A EP20859077A EP4021690A4 EP 4021690 A4 EP4021690 A4 EP 4021690A4 EP 20859077 A EP20859077 A EP 20859077A EP 4021690 A4 EP4021690 A4 EP 4021690A4
Authority
EP
European Patent Office
Prior art keywords
multiomics
detergent
design
sample preparation
novel new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20859077.8A
Other languages
German (de)
French (fr)
Other versions
EP4021690A1 (en
Inventor
Alexandre ZOUGMAN
Sandra WILSON
John Paul WILSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protifi LLC
Original Assignee
Protifi LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protifi LLC filed Critical Protifi LLC
Publication of EP4021690A1 publication Critical patent/EP4021690A1/en
Publication of EP4021690A4 publication Critical patent/EP4021690A4/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/043—Hinged closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0854—Double walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP20859077.8A 2019-08-30 2020-08-31 Detergent-free simultaneous multiomics sample preparation method using novel new vesicle design Pending EP4021690A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962894201P 2019-08-30 2019-08-30
PCT/US2020/048840 WO2021042070A1 (en) 2019-08-30 2020-08-31 Detergent-free simultaneous multiomics sample preparation method using novel new vesicle design

Publications (2)

Publication Number Publication Date
EP4021690A1 EP4021690A1 (en) 2022-07-06
EP4021690A4 true EP4021690A4 (en) 2023-10-04

Family

ID=74684748

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20859077.8A Pending EP4021690A4 (en) 2019-08-30 2020-08-31 Detergent-free simultaneous multiomics sample preparation method using novel new vesicle design

Country Status (5)

Country Link
US (1) US20220326126A1 (en)
EP (1) EP4021690A4 (en)
CN (1) CN114585486A (en)
CA (1) CA3149447A1 (en)
WO (1) WO2021042070A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023039404A1 (en) * 2021-09-08 2023-03-16 Meso Scale Technologies, Llc. Sample collection device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110313143A1 (en) * 2008-12-15 2011-12-22 Life Technologies Corporation Nucleic acid purification apparatus and method
WO2013166605A1 (en) * 2012-05-09 2013-11-14 Dalhousie University Filtration and extraction assembly
US20180136194A1 (en) * 2016-11-16 2018-05-17 Quidel Corporation Device for whole blood separation

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254315A (en) * 1991-07-26 1993-10-19 E. I. Du Pont De Nemours And Company Carrier device
US6221655B1 (en) * 1998-08-01 2001-04-24 Cytosignal Spin filter assembly for isolation and analysis
US6995018B1 (en) * 1999-04-09 2006-02-07 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complex formed by N-linked glycoproteins (SIBLINGS)and Factor H
SE9904539D0 (en) * 1999-12-10 1999-12-10 Alphahelix Ab Method and device for handling samples and reagents
DE602004026473D1 (en) * 2003-12-15 2010-05-20 Preentec Ag PROCESS FOR CONCENTRATING AND CLEANING BIOLOGICAL COMPOUNDS
US7240572B2 (en) * 2004-02-18 2007-07-10 Millipore Corporation Vacuum assisted affinity chromatography device and method
US20100281955A1 (en) * 2009-05-05 2010-11-11 Pressure Biosciences Inc. Microtube and related methods therefor
EP2726595A1 (en) * 2011-07-01 2014-05-07 Qiagen GmbH Filter module in biomolecule isolation
CN203048937U (en) * 2013-02-05 2013-07-10 杭州百迈生物技术有限公司 Nucleic acid purification column for negative pressure method and centrifugal method
ITMI20131502A1 (en) * 2013-09-11 2015-03-12 Gvs Spa METHOD FOR REALIZING A MINIFIAL WITH NUMBER OF COMPOUNDS REDUCED AND MINIFIABLE SO IT HAS OBTAINED
GB201318840D0 (en) * 2013-10-24 2013-12-11 Univ Leeds Method and device for protein preparation
US10495614B2 (en) * 2014-12-30 2019-12-03 Dionex Corporation Vial cap and method for removing matrix components from a liquid sample
WO2018075900A1 (en) * 2016-10-21 2018-04-26 Lutz Thomas R Systems and methods for de-oxygenation of a closed container

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110313143A1 (en) * 2008-12-15 2011-12-22 Life Technologies Corporation Nucleic acid purification apparatus and method
WO2013166605A1 (en) * 2012-05-09 2013-11-14 Dalhousie University Filtration and extraction assembly
US20180136194A1 (en) * 2016-11-16 2018-05-17 Quidel Corporation Device for whole blood separation

Also Published As

Publication number Publication date
CN114585486A (en) 2022-06-03
CA3149447A1 (en) 2021-03-04
US20220326126A1 (en) 2022-10-13
EP4021690A1 (en) 2022-07-06
WO2021042070A1 (en) 2021-03-04

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