EP4007522A4 - Data-based mental disorder research and treatment systems and methods - Google Patents

Data-based mental disorder research and treatment systems and methods

Info

Publication number
EP4007522A4
EP4007522A4 EP20851017.2A EP20851017A EP4007522A4 EP 4007522 A4 EP4007522 A4 EP 4007522A4 EP 20851017 A EP20851017 A EP 20851017A EP 4007522 A4 EP4007522 A4 EP 4007522A4
Authority
EP
European Patent Office
Prior art keywords
methods
data
treatment systems
mental disorder
based mental
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20851017.2A
Other languages
German (de)
French (fr)
Other versions
EP4007522A1 (en
Inventor
Hailey B Lefkofsky
Christopher N Vlangos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tempus Ai Inc
Original Assignee
Tempus Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/056713 external-priority patent/WO2020081795A1/en
Application filed by Tempus Labs Inc filed Critical Tempus Labs Inc
Publication of EP4007522A1 publication Critical patent/EP4007522A1/en
Publication of EP4007522A4 publication Critical patent/EP4007522A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/165—Evaluating the state of mind, e.g. depression, anxiety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G16H70/40—ICT specially adapted for the handling or processing of medical references relating to drugs, e.g. their side effects or intended usage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
EP20851017.2A 2019-08-02 2020-08-03 Data-based mental disorder research and treatment systems and methods Pending EP4007522A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962882466P 2019-08-02 2019-08-02
PCT/US2019/056713 WO2020081795A1 (en) 2018-10-17 2019-10-17 Data based cancer research and treatment systems and methods
PCT/US2020/044795 WO2021026097A1 (en) 2019-08-02 2020-08-03 Data-based mental disorder research and treatment systems and methods

Publications (2)

Publication Number Publication Date
EP4007522A1 EP4007522A1 (en) 2022-06-08
EP4007522A4 true EP4007522A4 (en) 2024-01-24

Family

ID=74504485

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20851017.2A Pending EP4007522A4 (en) 2019-08-02 2020-08-03 Data-based mental disorder research and treatment systems and methods

Country Status (5)

Country Link
EP (1) EP4007522A4 (en)
JP (1) JP2022543240A (en)
AU (1) AU2020326626A1 (en)
CA (1) CA3149381A1 (en)
WO (1) WO2021026097A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110305949A (en) * 2019-05-07 2019-10-08 中国人民解放军联勤保障部队第九0四医院 The analysis of schizophrenia disease mouse model hippocampus mRNA sequence and kit
CN113466467A (en) * 2021-06-17 2021-10-01 中国人民解放军军事科学院军事医学研究院 Marker for detecting anxiety and depression and application thereof
CN113355408A (en) * 2021-06-29 2021-09-07 山西医科大学第一医院 Molecular marker for detecting/curative effect evaluating early-onset schizophrenia and application thereof
CN114699080B (en) * 2022-04-28 2023-04-25 电子科技大学 Driver mental stress degree identification method based on fusion characteristics
CN114736961A (en) * 2022-05-23 2022-07-12 武汉儿童医院 Diagnostic reagent for recognizing senile depression based on transcription factor, application and system
CN116559451B (en) * 2023-04-07 2023-12-05 山东大学 Application of FBXL20 in diagnosis and treatment of depression

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140370582A1 (en) * 2006-05-18 2014-12-18 Caris Mpi, Inc. System and method for determining individualized medical intervention for a disease state
US20190088366A1 (en) * 2015-12-18 2019-03-21 Cognoa, Inc. Platform and system for digital personalized medicine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070031853A1 (en) * 1999-02-22 2007-02-08 Variagenics, Inc., A Delaware Corporation Gene sequence variations with utility in determining the treatment of neurological or psychiatric disease
AU2005271244A1 (en) * 2004-08-13 2006-02-16 The Regents Of The University Of California Compositions and methods for determining and predicting treatment responses for depression and anxiety
WO2007120480A2 (en) * 2006-04-03 2007-10-25 President And Fellows Of Harvard College Systems and methods for predicting effectiveness in the treatment of psychiatric disorders, including depression
WO2007121319A2 (en) * 2006-04-14 2007-10-25 University Of California Compostions and methods for determining and predicting treatment responses for depression and anxiety

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140370582A1 (en) * 2006-05-18 2014-12-18 Caris Mpi, Inc. System and method for determining individualized medical intervention for a disease state
US20190088366A1 (en) * 2015-12-18 2019-03-21 Cognoa, Inc. Platform and system for digital personalized medicine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ARLOTH JANINE ET AL: "Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders", NEURON, vol. 86, no. 5, 3 June 2015 (2015-06-03), pages 1189 - 1202, XP029236244, ISSN: 0896-6273, DOI: 10.1016/J.NEURON.2015.05.034 *
See also references of WO2021026097A1 *
YI ZHENGHUI ET AL: "Blood-Based Gene Expression Profiles Models for Classification of Subsyndromal Symptomatic Depression and Major Depressive Disorder", PLOS ONE, vol. 7, no. 2, 13 February 2012 (2012-02-13), pages e31283, XP055791511, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278427/pdf/pone.0031283.pdf> DOI: 10.1371/journal.pone.0031283 *

Also Published As

Publication number Publication date
WO2021026097A1 (en) 2021-02-11
EP4007522A1 (en) 2022-06-08
AU2020326626A1 (en) 2022-03-10
CA3149381A1 (en) 2021-02-11
JP2022543240A (en) 2022-10-11

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Owner name: TEMPUS AI, INC.