EP3993744A1 - Apprentissage de mode d'auto-phacoémulsification pour une chirurgie ophtalmique - Google Patents

Apprentissage de mode d'auto-phacoémulsification pour une chirurgie ophtalmique

Info

Publication number
EP3993744A1
EP3993744A1 EP20834243.6A EP20834243A EP3993744A1 EP 3993744 A1 EP3993744 A1 EP 3993744A1 EP 20834243 A EP20834243 A EP 20834243A EP 3993744 A1 EP3993744 A1 EP 3993744A1
Authority
EP
European Patent Office
Prior art keywords
occlusion
energy
phacoemulsification
phaco
values
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20834243.6A
Other languages
German (de)
English (en)
Other versions
EP3993744A4 (fr
Inventor
Kirk Todd
Johan Ekvall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Surgical Vision Inc
Original Assignee
Johnson and Johnson Surgical Vision Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/460,978 external-priority patent/US11957620B2/en
Application filed by Johnson and Johnson Surgical Vision Inc filed Critical Johnson and Johnson Surgical Vision Inc
Publication of EP3993744A1 publication Critical patent/EP3993744A1/fr
Publication of EP3993744A4 publication Critical patent/EP3993744A4/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A61F9/00745—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments using mechanical vibrations, e.g. ultrasonic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/74—Suction control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Definitions

  • the present disclosure relates to a learning auto phacoemulsification mode for ophthalmic surgery and, more specifically, the learning of actual phaco energy setpoints over a period of time which then is recorded during an occlusion break.
  • an ophthalmic surgical apparatus is used to perform surgical procedures in a patient’s eye.
  • An ophthalmic surgical apparatus typically includes a handheld medical implement or tool, such as a handpiece with a tip and/or sleeve, and operating controls for regulating settings or functions of the apparatus and tool. Operation of the tool requires control of various operating settings or functions based on the type of tool used.
  • Such apparatuses typically include a control module, power supply, an irrigation source, one or more aspiration pumps, as well as associated electronic hardware and software for operating a multifunction handheld surgical tool.
  • the handpiece may include a needle or tip which is ultrasonically driven once placed with the incision to, for example, emulsify the lens of the eye. In various surgical procedures, these components work together to, for example, emulsify eye tissue, irrigate the eye with a saline solution, and aspirate the emulsified lens from the eye.
  • Intraocular pressure is the fluid pressure inside the anterior chamber of the eye.
  • intraocular pressure may vary depending on the time of day, activities of the patient, fluid intake, medications, etc.
  • Intraocular pressure may be measured as static (a specific value) or dynamic (a range of values).
  • static IOP and dynamic IOP of a patient’s eye can fluctuate greatly during an ophthalmic surgery procedure. It is well known that the IOP in an anterior chamber of the eye is required to be controlled and maintained during such surgical procedures to avoid damage to the patient’s eye. For the correct function of the eye and its structure (e.g. shape) and to preserve sharp and undamaged vision, it is very important to keep the IOP in normal, physiological values.
  • An exemplary type of ophthalmic surgery is phacoemulsification.
  • Phacoemulsification includes making a corneal and/or scleral incision and the insertion of a phacoemulsification handpiece that includes a needle or tip that is ultrasonically driven to emulsify, or liquefy, the lens.
  • a phacoemulsification system typically includes a handpiece coupled to an irrigation source and an aspiration pump.
  • the handpiece includes a distal tip that emits ultrasonic energy to emulsify a crystalline lens within the patient’s eye.
  • the handpiece includes one or more irrigation ports proximal to the distal tip and coupled to the irrigation source via an irrigation input line.
  • the handpiece further includes an aspiration port at the distal tip that is coupled to the aspiration pump via an aspiration output line.
  • fluid from the irrigation source (which may be a bottle or bag of saline solution that is elevated above the patient's eye, to establish positive pressure by gravity, and/or with external pressure source) is irrigated into the eye via the irrigation line and the irrigation port(s).
  • This fluid is directed to the crystalline lens in the patient’s eye in order to maintain the anterior chamber and capsular bag and replenish the fluid aspirated away with the emulsified crystalline lens material.
  • the irrigation fluid in the patient’s eye and the crystalline lens material is aspirated or removed from the eye by the aspiration pump and line via the aspiration port.
  • cataract surgery is a complex procedure performed by highly skilled surgeons using extremely complex and expensive equipment.
  • the surgeon undergoes years of training to perfect their technique while using only a fraction of the system’s capabilities and features.
  • cataract tissue which may be denser, may be removed by aspiration.
  • aspiration When the material has been emulsified or softened to the point where aspiration is sufficient to remove the material an occlusion break occurs.
  • a post-occlusion surge could potentially damage the tissue.
  • the surgeon may anticipate this occurrence and discontinue ultrasonic power to prevent any damage to the eye.
  • the surgeon may apply more power than needed.
  • the human reaction time is approximately 350 milliseconds (ms). That means the patient may be subjected to an additional 350 ms or more of ultrasonic energy every occlusion break.
  • the surgeon may confront a multitude of decisions as he/she attempts to balance the inflow and outflow of fluid in the eye while trying to control the movement of material with the handpiece and deciding when to apply ultrasonic power.
  • lens material may create a blockage at the tip preventing fluid from being evacuated. This blockage can result in post-occlusion surge and lead to eye trauma.
  • the surgeon has to decide whether to preempt the surge by clearing the occlusion by applying power to knock the piece off the tip and having to reacquire the piece or discontinue the procedure by gradually (or quickly) releasing the foot pedal to change the pump speed and/or vacuum.
  • cataract lens material in the aspirating phacoemulsification handpiece may flow back into the eye chamber leading to a longer, less efficient cataract extraction.
  • Other techniques include steps to ramp from a user-defined baseline phaco energy setting on occlusion onset until the occlusion has cleared.
  • the user-defined baseline setting if too low, may cause extra phaco time due to the time required to ramp to an occlusion break power.
  • the user-defined baseline is too high, an excess of phaco energy can, and will, be imparted to the patient’s eye.
  • the present invention provides a system for recording, over a period of time, energy setpoints at the time of occlusion breaks.
  • the recorded values, or Occlusion Break Values provide data points to be inputted to assist in deriving and determining what is considered to be a phaco energy setting amount for phacoemulsification surgery when taken in combination with a myriad of different parameters, such as lifetime recorded values, surgeon-specific data inputs, and cataract grades, or the like.
  • the baseline phaco energy setting amount is therefore considered to be a learned value based on historical data gathered from prior as well as current phacoemulsification surgical procedures.
  • An auto phaco phacoemulsification system for learning phaco energy setpoints during phacoemulsification surgery comprising a surgical console having at least one system bus communicatively connected to at least one computing processor capable of accessing at least one computing memory associated with the at least one computing processor, wherein the surgical console is configured to determine an energy setpoint based on one or more values recorded in response to one or more occlusion breaks; and at least one vacuum source associated with the surgical console for providing a vacuum pressure and at least one energy source associated with the surgical console for providing ultrasonic energy based on the determined energy setpoint.
  • FIG. 1 illustrates a diagram of an exemplary phacoemulsification/ diathermy/vitrectomy system in accordance with the present disclosure, the system including a control module to control various features of the system; and
  • FIG. 2 illustrates an alternative phacoemulsification/ diathermy/vitrectomy system and illustrated connected to various components of the system in order to determine characteristics or features of the components;
  • FIG. 3 illustrates a graphical representation of an embodiment of Auto Phaco
  • FIG. 4 illustrates a graphical representation of an embodiment of Auto Phaco. DETAILED DESCRIPTION
  • FIGS. 1 and 2 illustrate an exemplary phacoemulsification/diathermy/vitrectomy system 100.
  • the system 100 includes, for example, a handpiece or wand 20, an irrigation source 30, an aspiration source 40, an optional pressure supply 50, and a control module 60.
  • fluid is controllably directed through the system 100 in order to irrigate a patient’s eye, illustrated representatively at 10, during an ocular surgical procedure.
  • irrigation source 30, aspiration source 40, optional pressure supply 50 and control module 60 are well-known in the art and are embodied in this disclosure.
  • the irrigation source 30 is configured to supply a predetermined amount of fluid to the handpiece 20 for use during a surgical operation.
  • fluid is supplied to, for example, stabilize or maintain a certain Intraocular Pressure (IOP) in the anterior chamber of the eye during surgery, as well as provide means for fluidly transporting any particles (e.g. lens particulates that are created during emulsification) out of the eye.
  • IOP Intraocular Pressure
  • Various aspects (e.g. the flow rate, pressure) of fluid flow into and out of the anterior chamber of the eye will typically affect the operations of the surgical procedure.
  • fluid may flow from the irrigation source 30 to the handpiece 20 via an irrigation line 32.
  • the irrigation source 30 may be any type of irrigation source 30 that can create and control a constant fluid flow.
  • the irrigation source is elevated to a predetermined height via an extension arm 38.
  • the irrigation source 30 may be configured to be an elevated drip bag 33/34 or bottle that supplies a steady state of fluid 36 to the irrigation line 32.
  • the pressure supply 50/58 may be coupled to the irrigation source 30 in order to maintain a constant pressure in the irrigation source 30 as fluid exits the irrigation source 30, as is known in the industry. Other embodiments of a uniform irrigation source are well-known in the art.
  • fluid may be aspirated from the patient’s eye, illustrated representatively at 10, via the handpiece 20 to flow through an aspiration line 42 to the aspiration source 40.
  • the aspiration source 40 may be any type of aspiration source 40 that aspirates fluid and material from the eye.
  • the aspiration source 40 may be configured to be a flow-based pump 44 (such as a peristaltic pump) or a vacuum -based pump (such as a Venturi pump) that are well-known in the art.
  • the aspiration source 40 may create a vacuum system to pump fluid and/or material out of the eye via the aspiration line 42.
  • a sensor system 52 may be present to measure the pressure, flow and/or vacuum that the aspiration source 40 creates.
  • the sensor may be located anywhere in the handpiece and/or system. Other embodiments of an aspiration source are well-known in the art.
  • the irrigation port 26 is fluidly coupled to the irrigation line 32 to receive fluid flow from the irrigation source 30, and the aspiration port 28 is fluidly coupled to the aspiration line 42 to receive fluid and/or material flow from the eye.
  • the pressure in the aspiration line may be measured by the system, e.g. by the sensor system 52.
  • the handpiece 20 and the tip 24 may further emit ultrasonic energy into the patient’s eye, for instance, to emulsify or break apart the crystalline lens within the patient’s eye.
  • Such emulsification may be accomplished by any known methods in the industry, such as, for example, a vibrating unit (not shown) that is configured to ultrasonically vibrate and/or cut the lens, as is known in the art.
  • emulsification such as a laser
  • fluid from the irrigation source 30 is irrigated into the eye via the irrigation line 32 and the irrigation port 26.
  • the irrigation fluid and emulsified crystalline lens material are aspirated from the eye by the aspiration source 40 via the aspiration port 28 and the aspiration line 42.
  • Other medical techniques for removing a crystalline lens also typically include irrigating the eye and aspirating lens parts and other liquids. Additionally, other procedures may include irrigating the eye and aspirating the irrigating fluid within concomitant destruction, alternation or removal of the lens.
  • the aspiration source 40 is configured to aspirate or remove fluid and other materials from the eye in a steady, uniform flow rate.
  • the aspiration source 40 may be a Venturi pump, a peristaltic pump, or a combined Venturi and peristaltic pump.
  • a peristaltic pump 44 may be configured to include a rotating pump head 46 having rollers 48.
  • the aspiration line 42 is configured to engage with the rotating pump head 46 as it rotates about an axis.
  • the pump 44 directly controls the volume or rate of fluid flow, and the rate of fluid flow can be easily adjusted by adjusting the rotational speed of the pump head 46.
  • Other means of uniformly controlling fluid flow in an aspiration source 40 are well-known in the art.
  • the aspiration source 40 includes a combined Venturi and peristaltic pump, the aspiration source 40 may be controlled to automatically switch between the two types of pumps or user controlled to switch between the two types of pumps.
  • the control module 60 is configured to monitor and control various components of the system 100.
  • the control module 60 may monitor, control, and provide power to the pressure supply 50, the aspiration source 40, and/or the handpiece 20.
  • the control module 60 may be in a variety of forms as known in the art.
  • the control module 60 may include a microprocessor computer 62, a keyboard 64, and a display or screen 66, as illustrated in FIGS. 1 and 2.
  • the microprocessor computer 62 may be operably connected to and control the various other elements of the system, while the keyboard 64 and display 66 permit a user to interact with and control the system components as well.
  • a virtual keyboard on display 66 may be used instead of keyboard 64.
  • a system bus 68 may be further provided to enable the various elements to be operable in communication with each other.
  • the control module 60 may be powered by an energy source.
  • the energy source may be a power source - such as a 110v plug - or conventional commercial power sources.
  • the screen 66 may display various measurements, criteria or settings of the system 100 - such as the type of procedure, the phase of the procedure and duration of the phase, various parameters such as vacuum, flow rate, power, and values that may be input by the user, such as bottle height, sleeve size, tube length (irrigation and aspiration), tip size, vacuum rate, etc.
  • the screen 66 may be in the form of a graphical user interface (GUI) associated with the control module 60 and utilizing a touchscreen interface, for example.
  • GUI graphical user interface
  • the GUI may allow a user to monitor the characteristics of the system 100 or select settings or criteria for various components of the system. For instance, the GUI may permit a user to select or alter the maximum pressure being supplied by the pressure supply 50 to the irrigation source 30 via line 58.
  • the user may further control the operation of the phase of the procedure, the units of measurement used by the system 100, or the height of the irrigation source 30, as discussed below.
  • the GUI may further allow for the calibration and priming of the pressure in the irrigation
  • the system 100 may include a sensor system 52 configured in a variety of ways or located in various locations.
  • the sensor system 52 may include at least a first sensor or strain gauge 54 located along the irrigation line 32 and a second sensor or strain gauge 56 located along the aspiration line 42, as illustrated in FIG. 2.
  • Other locations for the sensors 54 and 56 are envisioned anywhere in the system 100, e.g. on the handpiece 20, and may be configured to determine a variety of variables that may be used to determine pressure measurements in the aspiration line, as discussed below. This information may be relayed from the sensor system 52 to the control module 60 to be used in the determination of the presence of an occlusion break.
  • the sensor system 52 may also include sensors to detect other aspects of the components used in the system, e.g. type of pump used, type of sleeve used, gauge of needle tip (size), etc.
  • DSP digital signal processor
  • ASIC application specific integrated circuit
  • FPGA field programmable gate array
  • a general purpose processor may be a microprocessor, but in the alternative, the processor may be any conventional processor, controller, microcontroller, or state machine.
  • a processor may also be implemented as a combination of computing devices, e.g., a combination of a DSP and a microprocessor, a plurality of microprocessors, one or more microprocessors in conjunction with a DSP core, or any other such configuration.
  • any options available for a particular medical device system may be employed with the present invention.
  • the available settings may include, but are not limited to, irrigation, aspiration, vacuum level, flow rate, pump type (flow based and/or vacuum based), pump speed, ultrasonic power (type and duration, e.g. burst, pulse, duty cycle, etc.), irrigation source height adjustment, linear control of settings, proportional control of settings, panel control of settings, and type (or“shape”) of response.
  • the present invention may learn from data derived during a phacoemulsification surgical procedure as part of an Auto Phaco phacoemulsification system. This learned data may then be utilized to calculate what is called a baseline phaco energy setting amount.
  • data may be derived from an actual phaco energy setpoint recorded at the time of an Auto Phaco occlusion break. An immediate occlusion onset/break may be recorded as an excess of phaco energy condition and in turn cause the learned value to decrease.
  • the recorded values also called Occlusion Break Values (OBV) may be recorded in a memory or suitable database management system.
  • Occlusion Break Values Occlusion Break Values
  • Other data storage techniques or devices may be used to provide adequate security to ensure privacy of patient data.
  • the stored OBV may be kept for a current case, such as during a current phacoemulsification surgical procedure, or over a lifetime of cases.
  • lifetime recorded values may be learned over many cases, such as more than five cases, for example, and may be contained in an individual surgeon’s saved data file. Even further, recorded values may be saved independently and may be associated with a cataract grade. Any suitable cataract grading formula or method may be used, such as the Lens Opacities Classification System III. Lifetime learned values may also contain a deviation value. The deviation value may be used to track the variability of a surgeon’s decision-making judgements with regard to a certain cataract grade.
  • This Lifetime variability value may then be used to determine a phaco energy setting amount to subtract from a learned Lifetime OBV for an Auto Phaco ramp starting point for a first Auto Phaco occlusion occurrence during a current case. Subsequent Auto Phaco ramp setpoints during the same case may then use the case-learned OBV minus the case variability value.
  • FIG. 3 provides a graphical explanation of Auto Phaco.
  • Ultrasound (US) phaco time and accumulated power have been shown to have a detrimental effect on endothelial cell densities. Surgeons routinely track the US time and accumulated power imparted to each patient’s eye.
  • the Auto Phaco phacoemulsification system minimizes this power by only turning on power when there is an occlusion event 321.
  • occlusion event 321 is shown and the relationship between the vacuum level changes (line 301), phaco power level changes (line 303), and aspiration flow rate changes (line 305) are shown.
  • the Auto Phaco may be able to set the Auto Phaco start point as close to the occlusion break setting as possible. A means of doing this would be for the phacoemulsification system to keep track of and learn the occlusion break setting.
  • the cataract hardness (cataract grade) may affect the occlusion breakpoint setting.
  • the Auto Phaco phacoemulsification system may learn the mean occlusion break setting on a per surgeon, and/or per selected cataract grade basis. The surgeon’s capability of judging the cataract grade before surgery may vary between surgeons.
  • the Auto Phaco phacoemulsification system keeps track of the stored mean deviation between the stored value and the value where occlusion break happens on a per surgeon and/or per cataract grade basis and use this value to adjust the ramp start value to accommodate for the variation. The better the surgeon can judge a cataract hardness the less US power would be needed.
  • the ramp start setpoint 413 is 5% below the occlusion break value 411 than that shown on FIG. 3. The 5% value is based on an example of a particular surgeon’s deviation value.

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  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un système pour apprendre des points de consigne d'énergie de phacoémulsification réels au moment de ruptures d'occlusion pendant une chirurgie ophtalmique. Des points de consigne d'énergie de phacoémulsification peuvent être enregistrés au cours de différentes périodes de temps, par exemple pendant des cas actuels et au cours d'une durée de vie de cas. Les données enregistrées peuvent ensuite être utilisées pour déterminer de futures quantités de réglage d'énergie de phacoémulsification.
EP20834243.6A 2019-07-02 2020-06-24 Apprentissage de mode d'auto-phacoémulsification pour une chirurgie ophtalmique Pending EP3993744A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/460,978 US11957620B2 (en) 2018-10-03 2019-07-02 Learning auto phaco phacoemulsification mode for ophthalmic surgery
PCT/IB2020/055973 WO2021001729A1 (fr) 2019-07-02 2020-06-24 Apprentissage de mode d'auto-phacoémulsification pour une chirurgie ophtalmique

Publications (2)

Publication Number Publication Date
EP3993744A1 true EP3993744A1 (fr) 2022-05-11
EP3993744A4 EP3993744A4 (fr) 2023-07-26

Family

ID=74100224

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20834243.6A Pending EP3993744A4 (fr) 2019-07-02 2020-06-24 Apprentissage de mode d'auto-phacoémulsification pour une chirurgie ophtalmique

Country Status (4)

Country Link
EP (1) EP3993744A4 (fr)
AU (1) AU2020298850A1 (fr)
CA (1) CA3145170A1 (fr)
WO (1) WO2021001729A1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625388B2 (en) * 2004-03-22 2009-12-01 Alcon, Inc. Method of controlling a surgical system based on a load on the cutting tip of a handpiece
WO2010052576A1 (fr) * 2008-11-07 2010-05-14 Oculus Optikgeräte GmbH Systeme, methode et code de logiciel informatique de classement de cataracte
CA2761420C (fr) * 2009-05-08 2017-03-28 Abbott Medical Optics Inc. Moteur d'auto-apprentissage pour l'affinage et l'optimisation d'actions chirurgicales

Also Published As

Publication number Publication date
EP3993744A4 (fr) 2023-07-26
AU2020298850A1 (en) 2022-01-20
WO2021001729A1 (fr) 2021-01-07
CA3145170A1 (fr) 2021-01-07

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