EP3990926A4 - System and method for target material retrieval from microwells - Google Patents

System and method for target material retrieval from microwells Download PDF

Info

Publication number
EP3990926A4
EP3990926A4 EP20833529.9A EP20833529A EP3990926A4 EP 3990926 A4 EP3990926 A4 EP 3990926A4 EP 20833529 A EP20833529 A EP 20833529A EP 3990926 A4 EP3990926 A4 EP 3990926A4
Authority
EP
European Patent Office
Prior art keywords
microwells
target material
material retrieval
retrieval
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20833529.9A
Other languages
German (de)
French (fr)
Other versions
EP3990926A1 (en
Inventor
Kalyan Handique
Swati Ranade
Vishal Sharma
Austin Payne
Sam Tuck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/867,235 external-priority patent/US10900032B2/en
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of EP3990926A1 publication Critical patent/EP3990926A1/en
Publication of EP3990926A4 publication Critical patent/EP3990926A4/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4077Concentrating samples by other techniques involving separation of suspended solids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877Flow chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1048General features of the devices using the transfer device for another function
    • G01N2035/1053General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase
EP20833529.9A 2019-06-26 2020-06-19 System and method for target material retrieval from microwells Pending EP3990926A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962866726P 2019-06-26 2019-06-26
US16/867,235 US10900032B2 (en) 2019-05-07 2020-05-05 System and method for automated single cell processing
PCT/US2020/038647 WO2020263700A1 (en) 2019-06-26 2020-06-19 System and method for target material retrieval from microwells

Publications (2)

Publication Number Publication Date
EP3990926A1 EP3990926A1 (en) 2022-05-04
EP3990926A4 true EP3990926A4 (en) 2023-09-13

Family

ID=74062083

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20833529.9A Pending EP3990926A4 (en) 2019-06-26 2020-06-19 System and method for target material retrieval from microwells

Country Status (8)

Country Link
EP (1) EP3990926A4 (en)
JP (1) JP2022539739A (en)
KR (1) KR20220024734A (en)
CN (1) CN113924494A (en)
AU (1) AU2020304355B2 (en)
CA (1) CA3138949A1 (en)
SG (1) SG11202112150RA (en)
WO (1) WO2020263700A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023188896A1 (en) * 2022-03-29 2023-10-05 ソニーグループ株式会社 Bioparticle analysis system, information processing device, and bioparticle analysis method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042832A1 (en) * 1998-02-23 1999-08-26 Bio-Nobile Oy Magnetic particle transfer device and method
WO2009076560A2 (en) * 2007-12-12 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for magnetic separation of cells
US20150225714A1 (en) * 2012-06-07 2015-08-13 Hitachi High-Technologies Corporation Kit for nucleic acid extraction and a nucleic acid extractor
US20160008814A1 (en) * 2013-03-13 2016-01-14 Denovo Sciences, Inc. System and method for capturing and analyzing cells
WO2016115025A1 (en) * 2015-01-13 2016-07-21 Gilson, Inc. Adapter for sliding magnetic particle separation
US20180036731A1 (en) * 2013-03-13 2018-02-08 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US20190060902A1 (en) * 2017-08-29 2019-02-28 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050106667A1 (en) * 2003-08-01 2005-05-19 Genentech, Inc Binding polypeptides with restricted diversity sequences
WO2008018904A2 (en) * 2006-01-18 2008-02-14 Argos Therapeutics, Inc. Systems and methods for processing samples in a closed container, and related devices
EP2765205B1 (en) * 2009-04-01 2016-05-18 DxTerity Diagnostics Incorporated Chemical ligation dependent probe amplification (CLPA)
JP5292267B2 (en) * 2009-12-16 2013-09-18 株式会社日立ハイテクノロジーズ SAMPLE PROCESSING DEVICE, SAMPLE PROCESSING METHOD, AND REACTION CONTAINER USED FOR THEM
JP2011234671A (en) * 2010-05-11 2011-11-24 Hitachi High-Technologies Corp Nucleic acid extraction device
WO2011162290A1 (en) * 2010-06-22 2011-12-29 ユニバーサル・バイオ・リサーチ株式会社 Device for trapping biologically-relevant substances and system for collecting biologically-relevant substances
EP2814942A4 (en) * 2012-02-13 2015-09-23 Neumodx Molecular Inc Microfluidic cartridge for processing and detecting nucleic acids
DK3384046T3 (en) * 2015-12-01 2021-07-12 Illumina Inc Digital microfluidic system for single cell isolation and characterization of analytes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042832A1 (en) * 1998-02-23 1999-08-26 Bio-Nobile Oy Magnetic particle transfer device and method
WO2009076560A2 (en) * 2007-12-12 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for magnetic separation of cells
US20150225714A1 (en) * 2012-06-07 2015-08-13 Hitachi High-Technologies Corporation Kit for nucleic acid extraction and a nucleic acid extractor
US20160008814A1 (en) * 2013-03-13 2016-01-14 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US20180036731A1 (en) * 2013-03-13 2018-02-08 Denovo Sciences, Inc. System and method for capturing and analyzing cells
WO2016115025A1 (en) * 2015-01-13 2016-07-21 Gilson, Inc. Adapter for sliding magnetic particle separation
US20190060902A1 (en) * 2017-08-29 2019-02-28 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells

Also Published As

Publication number Publication date
AU2020304355A1 (en) 2021-11-25
KR20220024734A (en) 2022-03-03
EP3990926A1 (en) 2022-05-04
WO2020263700A1 (en) 2020-12-30
JP2022539739A (en) 2022-09-13
CA3138949A1 (en) 2020-12-30
AU2020304355B2 (en) 2023-04-06
CN113924494A (en) 2022-01-11
SG11202112150RA (en) 2021-12-30

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