EP3976656A4 - Alk7 binding proteins and uses thereof - Google Patents
Alk7 binding proteins and uses thereof Download PDFInfo
- Publication number
- EP3976656A4 EP3976656A4 EP20813963.4A EP20813963A EP3976656A4 EP 3976656 A4 EP3976656 A4 EP 3976656A4 EP 20813963 A EP20813963 A EP 20813963A EP 3976656 A4 EP3976656 A4 EP 3976656A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- binding proteins
- alk7 binding
- alk7
- proteins
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101150009411 ACVR1C gene Proteins 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Child & Adolescent Psychology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962854619P | 2019-05-30 | 2019-05-30 | |
PCT/US2020/035141 WO2020243443A1 (en) | 2019-05-30 | 2020-05-29 | Alk7 binding proteins and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3976656A1 EP3976656A1 (en) | 2022-04-06 |
EP3976656A4 true EP3976656A4 (en) | 2023-07-12 |
Family
ID=73553930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20813963.4A Pending EP3976656A4 (en) | 2019-05-30 | 2020-05-29 | Alk7 binding proteins and uses thereof |
Country Status (8)
Country | Link |
---|---|
US (1) | US20220348685A1 (en) |
EP (1) | EP3976656A4 (en) |
JP (1) | JP2022534514A (en) |
KR (1) | KR20220016136A (en) |
CN (1) | CN114245805A (en) |
AU (1) | AU2020282764A1 (en) |
CA (1) | CA3142147A1 (en) |
WO (1) | WO2020243443A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023030503A1 (en) * | 2021-09-03 | 2023-03-09 | Laekna Therapeutics Shanghai Co., Ltd. | Anti-acvr2a antibodies and uses thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20170306028A1 (en) * | 2016-04-22 | 2017-10-26 | Acceleron Pharma Inc. | ALK7 Binding Proteins and Uses Thereof |
WO2019084249A1 (en) * | 2017-10-25 | 2019-05-02 | Acceleron Pharma Inc. | Alk7 binding proteins and uses thereof |
-
2020
- 2020-05-29 US US17/615,508 patent/US20220348685A1/en active Pending
- 2020-05-29 JP JP2021570762A patent/JP2022534514A/en active Pending
- 2020-05-29 CN CN202080043141.5A patent/CN114245805A/en active Pending
- 2020-05-29 KR KR1020217042386A patent/KR20220016136A/en unknown
- 2020-05-29 EP EP20813963.4A patent/EP3976656A4/en active Pending
- 2020-05-29 WO PCT/US2020/035141 patent/WO2020243443A1/en unknown
- 2020-05-29 CA CA3142147A patent/CA3142147A1/en active Pending
- 2020-05-29 AU AU2020282764A patent/AU2020282764A1/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20170306028A1 (en) * | 2016-04-22 | 2017-10-26 | Acceleron Pharma Inc. | ALK7 Binding Proteins and Uses Thereof |
WO2019084249A1 (en) * | 2017-10-25 | 2019-05-02 | Acceleron Pharma Inc. | Alk7 binding proteins and uses thereof |
Non-Patent Citations (1)
Title |
---|
See also references of WO2020243443A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2020243443A1 (en) | 2020-12-03 |
EP3976656A1 (en) | 2022-04-06 |
AU2020282764A1 (en) | 2021-12-02 |
JP2022534514A (en) | 2022-08-01 |
KR20220016136A (en) | 2022-02-08 |
US20220348685A1 (en) | 2022-11-03 |
CA3142147A1 (en) | 2020-12-03 |
CN114245805A (en) | 2022-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20211229 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 39/00 20060101ALI20230228BHEP Ipc: A61P 35/00 20060101ALI20230228BHEP Ipc: A61P 31/06 20060101ALI20230228BHEP Ipc: A61P 3/10 20060101ALI20230228BHEP Ipc: A61P 3/04 20060101ALI20230228BHEP Ipc: C07K 16/28 20060101AFI20230228BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20230609 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 39/00 20060101ALI20230602BHEP Ipc: A61P 35/00 20060101ALI20230602BHEP Ipc: A61P 31/06 20060101ALI20230602BHEP Ipc: A61P 3/10 20060101ALI20230602BHEP Ipc: A61P 3/04 20060101ALI20230602BHEP Ipc: C07K 16/28 20060101AFI20230602BHEP |