EP3963323A4 - Diagnose und behandlung von erkrankungen des autistischen spektrums im zusammenhang mit veränderten stoffwechselwegen - Google Patents

Diagnose und behandlung von erkrankungen des autistischen spektrums im zusammenhang mit veränderten stoffwechselwegen Download PDF

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Publication number
EP3963323A4
EP3963323A4 EP20798035.0A EP20798035A EP3963323A4 EP 3963323 A4 EP3963323 A4 EP 3963323A4 EP 20798035 A EP20798035 A EP 20798035A EP 3963323 A4 EP3963323 A4 EP 3963323A4
Authority
EP
European Patent Office
Prior art keywords
diagnosis
treatment
disorders associated
metabolic pathways
autism spectrum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20798035.0A
Other languages
English (en)
French (fr)
Other versions
EP3963323A1 (de
Inventor
Alan Meyer SMITH
Daniel BRAAS
Michael Ludwig
Elizabeth L. R. DONLEY
Robert Burrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stemina Biomarker Discovery Inc
Original Assignee
Stemina Biomarker Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemina Biomarker Discovery Inc filed Critical Stemina Biomarker Discovery Inc
Publication of EP3963323A1 publication Critical patent/EP3963323A1/de
Publication of EP3963323A4 publication Critical patent/EP3963323A4/de
Withdrawn legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP20798035.0A 2019-05-02 2020-04-28 Diagnose und behandlung von erkrankungen des autistischen spektrums im zusammenhang mit veränderten stoffwechselwegen Withdrawn EP3963323A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962842059P 2019-05-02 2019-05-02
PCT/US2020/030205 WO2020223197A1 (en) 2019-05-02 2020-04-28 Diagnosis and treatment of autism spectrum disorders associated with altered metabolic pathways

Publications (2)

Publication Number Publication Date
EP3963323A1 EP3963323A1 (de) 2022-03-09
EP3963323A4 true EP3963323A4 (de) 2023-05-31

Family

ID=73028718

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20798035.0A Withdrawn EP3963323A4 (de) 2019-05-02 2020-04-28 Diagnose und behandlung von erkrankungen des autistischen spektrums im zusammenhang mit veränderten stoffwechselwegen

Country Status (3)

Country Link
US (1) US20240210423A1 (de)
EP (1) EP3963323A4 (de)
WO (1) WO2020223197A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113077885A (zh) * 2021-03-12 2021-07-06 中山大学附属第七医院(深圳) 一种基于肠道代谢物的数据分析方法及装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160169915A1 (en) * 2013-07-09 2016-06-16 Stemina Biomarker Discovery, Inc. Biomarkers of autism spectrum disorder
EP3746796A1 (de) * 2018-01-29 2020-12-09 Stemina Biomarker Discovery, Inc. Diagnose und behandlung von autismus-spektrum-störungen auf basis von aminenhaltigen metabotypen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160169915A1 (en) * 2013-07-09 2016-06-16 Stemina Biomarker Discovery, Inc. Biomarkers of autism spectrum disorder
EP3746796A1 (de) * 2018-01-29 2020-12-09 Stemina Biomarker Discovery, Inc. Diagnose und behandlung von autismus-spektrum-störungen auf basis von aminenhaltigen metabotypen

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020223197A1 *
SMITH ALAN M ET AL: "Amino Acid Dysregulation Metabotypes: Potential Biomarkers for Diagnosis and Individualized Treatment for Subtypes of Autism Spectrum Disorder", BIOLOGICAL PSYCHIATRY, ELSEVIER, AMSTERDAM, NL, vol. 85, no. 4, 6 September 2018 (2018-09-06), pages 345 - 354, XP085580702, ISSN: 0006-3223, DOI: 10.1016/J.BIOPSYCH.2018.08.016 *

Also Published As

Publication number Publication date
EP3963323A1 (de) 2022-03-09
US20240210423A1 (en) 2024-06-27
WO2020223197A1 (en) 2020-11-05

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