EP3956024A4 - Liquid sildenafil citrate compositions - Google Patents

Liquid sildenafil citrate compositions Download PDF

Info

Publication number
EP3956024A4
EP3956024A4 EP20791799.8A EP20791799A EP3956024A4 EP 3956024 A4 EP3956024 A4 EP 3956024A4 EP 20791799 A EP20791799 A EP 20791799A EP 3956024 A4 EP3956024 A4 EP 3956024A4
Authority
EP
European Patent Office
Prior art keywords
liquid
sildenafil citrate
citrate compositions
compositions
sildenafil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20791799.8A
Other languages
German (de)
French (fr)
Other versions
EP3956024A1 (en
Inventor
Moshe Rogosnitzky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ellamed Ip & Services Pte Ltd
Original Assignee
Ellamed Ip & Services Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ellamed Ip & Services Pte Ltd filed Critical Ellamed Ip & Services Pte Ltd
Publication of EP3956024A1 publication Critical patent/EP3956024A1/en
Publication of EP3956024A4 publication Critical patent/EP3956024A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP20791799.8A 2019-04-18 2020-04-17 Liquid sildenafil citrate compositions Withdrawn EP3956024A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962835523P 2019-04-18 2019-04-18
PCT/IB2020/053660 WO2020212931A1 (en) 2019-04-18 2020-04-17 Liquid sildenafil citrate compositions

Publications (2)

Publication Number Publication Date
EP3956024A1 EP3956024A1 (en) 2022-02-23
EP3956024A4 true EP3956024A4 (en) 2023-01-11

Family

ID=72836853

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20791799.8A Withdrawn EP3956024A4 (en) 2019-04-18 2020-04-17 Liquid sildenafil citrate compositions

Country Status (4)

Country Link
US (1) US20220193081A1 (en)
EP (1) EP3956024A4 (en)
CA (1) CA3137260A1 (en)
WO (1) WO2020212931A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112198243B (en) * 2020-09-10 2023-03-31 广州白云山医药集团股份有限公司白云山制药总厂 Method for detecting sildenafil citrate impurity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170216196A1 (en) * 2015-04-03 2017-08-03 Insys Development Company, Inc. Sildenafil sublingual spray formulations
US9968609B2 (en) * 2014-03-19 2018-05-15 Vigorous Solutions Ltd. Sildenafil solutions and methods of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100184722A1 (en) * 2008-12-19 2010-07-22 Shimoda Biotech (Pty) Ltd Inclusion complexes of alpha-cyclodextrin and sildenafil salt
WO2011030351A2 (en) * 2009-09-03 2011-03-17 Rubicon Research Private Limited Taste - masked pharmaceutical compositions
US20140335153A1 (en) * 2013-05-09 2014-11-13 Cure Pharmaceutical Corporation Thin film with high load of active ingredient

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9968609B2 (en) * 2014-03-19 2018-05-15 Vigorous Solutions Ltd. Sildenafil solutions and methods of making and using same
US20170216196A1 (en) * 2015-04-03 2017-08-03 Insys Development Company, Inc. Sildenafil sublingual spray formulations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020212931A1 *

Also Published As

Publication number Publication date
WO2020212931A1 (en) 2020-10-22
CA3137260A1 (en) 2020-10-22
EP3956024A1 (en) 2022-02-23
US20220193081A1 (en) 2022-06-23

Similar Documents

Publication Publication Date Title
EP3871694A4 (en) Composition
EP3672944A4 (en) Cleaning compositions
EP3882323A4 (en) Composition
EP3956425A4 (en) Liquid concentrated surfactant compositions
EP3999039A4 (en) Pretomanid compositions
EP3941942A4 (en) Composition
EP3820980A4 (en) Esterquat compositions
EP3985087A4 (en) Flavor composition
EP3981256A4 (en) Composition
EP3954721A4 (en) Composition
EP3977857A4 (en) Herbicide composition
EP3878518A4 (en) Flavor composition
EP3897732A4 (en) Cannabinoid-containing composition
EP3774680A4 (en) Cleaning compositions
EP3883536A4 (en) Improved self-tanning compositions
EP3826606A4 (en) Liquid fragrance compositions
EP3956024A4 (en) Liquid sildenafil citrate compositions
EP3818102A4 (en) Novel compositions for bitterants
EP3808785A4 (en) Composition
EP3965795A4 (en) Stable albuvirtide compositions
EP3769784A4 (en) Inflammation-suppressing composition
EP3777542A4 (en) Breadmaking composition
EP4052761A4 (en) Fragrance composition
EP3985062A4 (en) Composition
EP3914076A4 (en) Anti-apicomplexan compositions

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20211108

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Free format text: PREVIOUS MAIN CLASS: A61P0015100000

Ipc: A61K0009000000

A4 Supplementary search report drawn up and despatched

Effective date: 20221213

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 15/10 20060101ALI20221207BHEP

Ipc: A61K 47/26 20060101ALI20221207BHEP

Ipc: A61K 47/10 20170101ALI20221207BHEP

Ipc: A61K 31/519 20060101ALI20221207BHEP

Ipc: A61K 9/00 20060101AFI20221207BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20230720