EP3938114A4 - Method and apparatus for magnetic bead manipulation - Google Patents

Method and apparatus for magnetic bead manipulation Download PDF

Info

Publication number
EP3938114A4
EP3938114A4 EP20772594.6A EP20772594A EP3938114A4 EP 3938114 A4 EP3938114 A4 EP 3938114A4 EP 20772594 A EP20772594 A EP 20772594A EP 3938114 A4 EP3938114 A4 EP 3938114A4
Authority
EP
European Patent Office
Prior art keywords
magnetic bead
bead manipulation
manipulation
magnetic
bead
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP20772594.6A
Other languages
German (de)
French (fr)
Other versions
EP3938114B1 (en
EP3938114A1 (en
Inventor
Hannah Pezzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Siemens Healthcare Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Inc filed Critical Siemens Healthcare Diagnostics Inc
Publication of EP3938114A1 publication Critical patent/EP3938114A1/en
Publication of EP3938114A4 publication Critical patent/EP3938114A4/en
Application granted granted Critical
Publication of EP3938114B1 publication Critical patent/EP3938114B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/286—Magnetic plugs and dipsticks disposed at the inner circumference of a recipient, e.g. magnetic drain bolt
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/30—Combinations with other devices, not otherwise provided for
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
EP20772594.6A 2019-03-15 2020-01-28 Method and apparatus for magnetic bead manipulation Active EP3938114B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962819073P 2019-03-15 2019-03-15
US201962819018P 2019-03-15 2019-03-15
PCT/US2020/015303 WO2020190377A1 (en) 2019-03-15 2020-01-28 Method and apparatus for magnetic bead manipulation

Publications (3)

Publication Number Publication Date
EP3938114A1 EP3938114A1 (en) 2022-01-19
EP3938114A4 true EP3938114A4 (en) 2022-04-27
EP3938114B1 EP3938114B1 (en) 2024-01-10

Family

ID=72521096

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20772594.6A Active EP3938114B1 (en) 2019-03-15 2020-01-28 Method and apparatus for magnetic bead manipulation

Country Status (3)

Country Link
US (1) US11340244B2 (en)
EP (1) EP3938114B1 (en)
WO (1) WO2020190377A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329124A1 (en) * 2009-11-13 2012-12-27 Universal Bio Research Co., Ltd. Magnetic reagent, magnetic reagent kit, method for treating magnetic carriers, and treatment device therefor
US20170152509A1 (en) * 2014-05-23 2017-06-01 Shimadzu Corporation Method for operating magnetic body particles and device for operating magnetic body particles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI851702A0 (en) 1985-04-29 1985-04-29 Labsystems Oy FOERFARANDE OCH ANORDNING FOER UTFOERING IMMUNOBESTAEMNINGAR.
US5200084A (en) 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
DE69429159T2 (en) 1993-02-01 2002-08-14 Thermo Labsystems Oy Helsinki Method for a specific magnetic particle binding test
FI990082A0 (en) 1999-01-18 1999-01-18 Labsystems Oy Purification process using magnetic particles
US8557743B2 (en) 2002-09-05 2013-10-15 Dyax Corp. Display library process
FI20051248L (en) * 2005-12-02 2007-06-03 Bio Nobile Oy Enrichment unit and enrichment method for biological components
US8071395B2 (en) 2007-12-12 2011-12-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and apparatus for magnetic separation of cells
FI20115175A0 (en) 2011-02-23 2011-02-23 Helsinki Thermo Fisher Scient Oy Particle processing
US9128017B2 (en) 2013-03-19 2015-09-08 Rarecyte, Inc. Device, systems and methods for analyzing a target analyte
EP2835178B1 (en) 2013-08-06 2017-04-12 Yantai AusBio Laboratories Co., Ltd. Centrifuge and method for centrifuging a reaction vessel unit
US20150153259A1 (en) 2013-12-03 2015-06-04 BioMagnetic Solutions, LLC Multi-parameter high gradient magnetic separator and methods of use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329124A1 (en) * 2009-11-13 2012-12-27 Universal Bio Research Co., Ltd. Magnetic reagent, magnetic reagent kit, method for treating magnetic carriers, and treatment device therefor
US20170152509A1 (en) * 2014-05-23 2017-06-01 Shimadzu Corporation Method for operating magnetic body particles and device for operating magnetic body particles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020190377A1 *

Also Published As

Publication number Publication date
US20220043016A1 (en) 2022-02-10
US11340244B2 (en) 2022-05-24
WO2020190377A1 (en) 2020-09-24
EP3938114B1 (en) 2024-01-10
EP3938114A1 (en) 2022-01-19

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