EP3937936A4 - Inhibition de la protéine de liaison à un élément sensible à l'amp cyclique (creb) - Google Patents

Inhibition de la protéine de liaison à un élément sensible à l'amp cyclique (creb) Download PDF

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Publication number
EP3937936A4
EP3937936A4 EP20773477.3A EP20773477A EP3937936A4 EP 3937936 A4 EP3937936 A4 EP 3937936A4 EP 20773477 A EP20773477 A EP 20773477A EP 3937936 A4 EP3937936 A4 EP 3937936A4
Authority
EP
European Patent Office
Prior art keywords
creb
binding protein
responsive element
cyclic amp
inhibiting cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20773477.3A
Other languages
German (de)
English (en)
Other versions
EP3937936A1 (fr
Inventor
George Luke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forma Therapeutics Inc
Original Assignee
Forma Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forma Therapeutics Inc filed Critical Forma Therapeutics Inc
Publication of EP3937936A1 publication Critical patent/EP3937936A1/fr
Publication of EP3937936A4 publication Critical patent/EP3937936A4/fr
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP20773477.3A 2019-03-15 2020-03-13 Inhibition de la protéine de liaison à un élément sensible à l'amp cyclique (creb) Pending EP3937936A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962819482P 2019-03-15 2019-03-15
PCT/US2020/022783 WO2020190780A1 (fr) 2019-03-15 2020-03-13 Inhibition de la protéine de liaison à un élément sensible à l'amp cyclique (creb)

Publications (2)

Publication Number Publication Date
EP3937936A1 EP3937936A1 (fr) 2022-01-19
EP3937936A4 true EP3937936A4 (fr) 2022-12-28

Family

ID=72520554

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20773477.3A Pending EP3937936A4 (fr) 2019-03-15 2020-03-13 Inhibition de la protéine de liaison à un élément sensible à l'amp cyclique (creb)

Country Status (7)

Country Link
EP (1) EP3937936A4 (fr)
CN (1) CN113874017A (fr)
AU (1) AU2020239990A1 (fr)
BR (1) BR112021016921A2 (fr)
CA (1) CA3132628A1 (fr)
MX (1) MX2021010829A (fr)
WO (1) WO2020190780A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11795168B2 (en) * 2020-09-23 2023-10-24 Forma Therapeutics, Inc. Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018073586A1 (fr) * 2016-10-18 2018-04-26 Cellcentric Ltd Composés pharmaceutiques

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455564B1 (en) * 1999-01-06 2002-09-24 Pharmacia & Upjohn Company Method of treating sexual disturbances
HUP0203976A3 (en) * 2002-11-15 2004-08-30 Sanofi Aventis Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them
GB201504689D0 (en) * 2015-03-19 2015-05-06 Glaxosmithkline Ip Dev Ltd Chemical compounds
TWI846350B (zh) * 2017-09-15 2024-06-21 美商佛瑪治療公司 作為ＣＢＰ／ｐ３００抑制劑之四氫－咪唑並喹啉化合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018073586A1 (fr) * 2016-10-18 2018-04-26 Cellcentric Ltd Composés pharmaceutiques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MOSES MOUSTAKIM ET AL: "Discovery of a PCAF Bromodomain Chemical Probe", ANGEWANDTE CHEMIE, WILEY - V C H VERLAG GMBH & CO. KGAA, DE, vol. 129, no. 3, 14 December 2016 (2016-12-14), pages 845 - 849, XP071371206, ISSN: 0044-8249, DOI: 10.1002/ANGE.201610816 *
See also references of WO2020190780A1 *

Also Published As

Publication number Publication date
CN113874017A (zh) 2021-12-31
AU2020239990A1 (en) 2021-11-04
WO2020190780A1 (fr) 2020-09-24
EP3937936A1 (fr) 2022-01-19
MX2021010829A (es) 2021-12-10
CA3132628A1 (fr) 2020-09-24
BR112021016921A2 (pt) 2021-11-03

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