EP3879503A1 - Station de stockage et de distribution de médicaments - Google Patents

Station de stockage et de distribution de médicaments Download PDF

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Publication number
EP3879503A1
EP3879503A1 EP20162376.6A EP20162376A EP3879503A1 EP 3879503 A1 EP3879503 A1 EP 3879503A1 EP 20162376 A EP20162376 A EP 20162376A EP 3879503 A1 EP3879503 A1 EP 3879503A1
Authority
EP
European Patent Office
Prior art keywords
medicament
dispensing
storage
slide
feed section
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20162376.6A
Other languages
German (de)
English (en)
Inventor
Hardy Schmidt-Ellinger
Sebastian Josef Michael ILLIGEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson Rowa Germany GmbH
Original Assignee
Becton Dickinson Rowa Germany GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Rowa Germany GmbH filed Critical Becton Dickinson Rowa Germany GmbH
Priority to EP20162376.6A priority Critical patent/EP3879503A1/fr
Publication of EP3879503A1 publication Critical patent/EP3879503A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F17/00Coin-freed apparatus for hiring articles; Coin-freed facilities or services
    • G07F17/0092Coin-freed apparatus for hiring articles; Coin-freed facilities or services for assembling and dispensing of pharmaceutical articles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0076Medicament distribution means
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/005Special arrangements for insuring that only one single article may be dispensed at a time
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/02Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines
    • G07F11/04Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which magazines the articles are stored one vertically above the other
    • G07F11/16Delivery means
    • G07F11/24Rotary or oscillatory members
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/46Coin-freed apparatus for dispensing, or the like, discrete articles from movable storage containers or supports
    • G07F11/50Coin-freed apparatus for dispensing, or the like, discrete articles from movable storage containers or supports the storage containers or supports being rotatably mounted
    • G07F11/54Coin-freed apparatus for dispensing, or the like, discrete articles from movable storage containers or supports the storage containers or supports being rotatably mounted about vertical axes

Definitions

  • the present invention relates to a storage and dispensing station for drugs.
  • Modern blister machines such as those in the WO 2013/034504 A1 are disclosed, include, depending on the expansion stage, several hundred storage and dispensing stations for drugs. A plurality of medicament portions of a certain type of medicament are stored in each of these, and single or multiple medicament portions can be dispensed upon request. With the automatic blister packs, the drugs stored in the supply and dispensing stations are individually compiled and blistered for each patient according to the times prescribed by the doctor.
  • corresponding storage and dispensing stations for dispensing one or more individual drug portions are controlled.
  • a singling device separates a single drug portion and transfers it to a guide device of the blister machine via a dispensing opening.
  • a corresponding medicament portion is fed to a packaging device, possibly with the interposition of a collecting device, which blisters individual or several medicament portions in accordance with the medical specifications.
  • the separating device of known storage and dispensing stations used for separating medicament portions is usually constructed in the shape of a circular cylinder and is constructed in a corresponding guide space of the storage container.
  • a plurality of medicament channels are provided on the circumference of the separating device.
  • a drug channel loaded with at least one drug portion is rotated via a dispensing opening in the bottom surface of the storage container, so that the drug portion located in the channel can fall out of the drug channel.
  • a retaining device is provided above the medicament channel aligned with the dispensing opening.
  • this retaining device is guided in a slot which is made in the region of the medicament channels in the separating device.
  • capsule-shaped medicament portions In particular in the case of capsule-shaped medicament portions, the delivery speed is problematic when using known separating devices. Capsule-shaped drug portions are regularly very light, and there is also increased friction between the surface of the drug portions and the drug channels. Furthermore, in particular in the case of capsule-shaped medicament portions, the capsules become electrostatically charged, which creates an attraction for the medicament channel wall. Taken together, these circumstances cause capsule-shaped medicament portions to fall out of the medicament channel so slowly that the blistering speed of modern blister machines is restricted.
  • the object is achieved by a storage and dispensing station for medicament portions according to claim 1.
  • the storage and dispensing station according to the invention comprises a receiving space for medicament portions to be separated, the receiving space being one of the medicament portions to be separated Has drug portions adapted feed portion with a bottom portion and a dispensing opening.
  • the feed section ensures that only a defined number of medicament portions rests on the base section.
  • the feed section is adapted to the shape of the medicament portions to be separated.
  • the receiving space arranged above the feed section can be designed differently depending on the medicament portions to be separated. If, for example, spherical medicament portions are to be separated, the receiving space can widen conically upwards. If, on the other hand, capsule-shaped medicament portions, for example, are to be separated, provision can be made for the shape of the receiving space to be the same as that of the feed section.
  • the supply and dispensing station further comprises an ejector device for moving a medicament portion in the ejection direction through the dispensing opening, the ejecting device having a slide movable in the feed section towards the dispensing opening and a slide drive coupled to the slide for moving the slide.
  • an active ejection device is provided according to the invention. It is true that in such a case it is necessary to provide a drive that is necessary for ejecting the medicament portions, but in such a case significantly higher delivery speeds can be achieved even with medicament portions that are otherwise rather “slowly” falling. Since no rotating singling device is used to isolate and dispense drug portions, there is significantly less drug dust and the storage and dispensing station has to be cleaned less frequently.
  • the storage and dispensing station furthermore comprises a lock which can be moved in the supply section and which is movable in the supply section in such a way that when a medicament portion is moved towards the dispensing opening prevents a movement of medicament portions in or into the supply portion is.
  • the lock itself can be moved completely within the feed section; alternatively, it is also conceivable that the movable lock is moved into or over the feed section via an opening in or over the feed section in such a way that a medicament portion is prevented from slipping afterwards.
  • Another advantage of the supply and dispensing station according to the invention is that more space is available for receiving medication portions due to the separation device that is not required.
  • a slide is provided for moving a medicament portion to be dispensed and a lock to prevent a medicament portion from sliding down.
  • These two components can be separate components that can be moved using different drives.
  • the slide and the lock are coupled in such a way that both can be moved via the slide drive provided according to the invention. A correspondingly synchronous movement is possible, since moving the lock is necessary when moving the slide.
  • the slide and the lock are designed as a unitary slide lock element, this slide lock element preferably being formed in one piece, for example as a kind of bolt, in which the end face serves as a slide and the "upper" circumferential section as a lock.
  • the dispensing opening is assigned a sensor which can detect the dispensing of a drug portion through the dispensing opening.
  • the use of the active ejection device enables a rapid dispensing of a medicament portion with all types of medicament portions, specifically with a simultaneous reduction in the development of medicament dust.
  • the sliding speed of a medicament portion into or in the feed section determines how quickly a further medicament portion can be dispensed.
  • the supply and dispensing station has a plurality of feed sections with a base section and a dispensing opening, each supply section being able to be coupled to the ejection device for dispensing a medicament portion.
  • the feed sections are moved in relation to the slide, that is to say another feed section is fed to the slide after a drug portion has been dispensed.
  • the plurality of Feed sections is arranged in a rotatable magazine unit, the magazine unit being coupled to a magazine drive in such a way that the magazine unit is rotated after the dispensing of a medicament portion from a feed portion in such a way that a medicament portion can be dispensed from another feed portion.
  • a preferred embodiment of the supply and dispensing station provides that the slide drive comprises an actuator coupled to the magazine unit, the coupling being designed in such a way that a rotary movement occurs after a medicament portion has been dispensed the magazine unit is effected.
  • a preferred embodiment provides that the magazine unit is arranged in the storage and dispensing station so that it can be changed.
  • the magazine unit will regularly be empty when changing. However, it can happen that a magazine unit is changed before all medicament portions have been dispensed - for example, when the picking device is stopped in the evening.
  • the supply and dispensing station comprises a safety device which is attached to the circumference of the Magazine unit is guided and which blocks the dispensing openings when the magazine unit is removed.
  • the speed at which the slide moves a medicament portion out of the dispensing opening determines the overall speed with which the supply and dispensing station can dispense medicament portions.
  • the slide drive comprises a lifting magnet.
  • a lifting magnet is structurally very simple and can be controlled extremely quickly. Furthermore, a very high ejection speed and force can be achieved with a lifting magnet.
  • the order-picking device in which the supply and delivery stations according to the invention are used, knows the filling level of these stations precisely and indicates to a user if refilling is necessary within a defined period of time. It has been found, however, that users want to be able to read the fill level optically. This can be achieved, for example, by making the area in which the medicament portions are stored from a transparent material.
  • a preferred embodiment provides that the receiving space and the feed section (s) have a viewing area that allows the filling level to be read off. This viewing area can, for example, simply be designed as a slot in the wall of the receiving space (if the type of medicament to be separated does not tend to form dust); alternatively, a transparent material can be used only in this area or it can be inserted into a slot.
  • Figures 13a and 13b Show detailed oblique views from below, with Figure 13b the receptacle for the magazine unit is omitted.
  • the supply and dispensing station 1 comprises a receiving trough 20 with an outer dispensing opening 21, in which a sensor 22 for detecting the expulsion of a medicament portion through the outer dispensing opening 21 is arranged.
  • a magazine unit 10 which is closed with a cover 2, is rotatably arranged in the receiving trough 20.
  • an ejector 30 is arranged, which is described in more detail with reference to the following figures.
  • the magazine unit 10 comprises a plurality of vertical receiving spaces 11 which, in the embodiment shown, are designed to receive medicament capsules.
  • Each receiving space 11 comprises a feed section with a bottom section 13 and a dispensing opening 12.
  • the dispensing openings 12 of the magazine unit 10 are aligned with the outer dispensing opening - in alternative embodiments without a magazine unit, the receiving trough 20 and thus the outer dispensing opening 21 can be omitted.
  • the sensor 22 can then be arranged directly at a dispensing opening 12.
  • Each of the receiving spaces shown comprises a viewing area 19 for determining the filling level of the receiving space.
  • the viewing area 19 is designed as a simple slit, since the capsule-shaped medicament portions to be separated do not tend to form dust.
  • a safety device 3 is indicated around the magazine unit, which is designed as a simple ring which rests on the outer wall of the magazine unit. If the magazine unit 10 is removed from the receiving trough 20, the safety device slides down and blocks the dispensing openings 12 of the magazine unit.
  • the magazine unit 10 When presented in accordance with Figure 4 the magazine unit 10 is omitted, and the arrangement of medicament portions 7 in a receiving space or feed section is shown.
  • the capsule-shaped medicament portions 7 are stored in the receiving spaces 11 like in a magazine.
  • the superimposed medicament portions slip afterwards when released, as can be seen in the following figures.
  • FIG 5 the ejector 30 is shown.
  • a lifting magnet 31, 32 is arranged in the embodiment shown, which via a coupling piece 35 with a in the Figures 7a and 7b shown slide lock element 40 is coupled.
  • the coupling piece 35 is also coupled to an actuator 50 which has two extensions 51 which are guided through openings 24 in the receiving trough 20.
  • the actuator 50 is preloaded with a spring 36 which is supported against a stop 37.
  • the actuator moves (in Figure 6 ) the spring 36 is further tensioned "upwards" so that the spring can bring about a return movement of the actuator.
  • the actuator 50 is coupled to a web 39 of the coupling piece 35 via a driver 53 which receives a lug 52 of the actuator in an elongated hole.
  • FIGS 7a and 7b show detailed views of the ejection device 30 and the slide lock element 40.
  • the slide lock element 40 is coupled to the lifting magnet 31, 32 via a coupling piece 35.
  • the slide lock element 40 comprises a slide 41 and a lock 42, the slide being formed by the end face of the slide lock element and the lock by the upper surface of the bolt-like slide lock element.
  • Figure 12 shows a front view of the preferred embodiment with the receptacle 20 omitted.
  • the arrangement of the actuator 50 below the magazine unit 10 can be seen. It is also easy to see that the extensions 51 of the actuator 50 protrude "upwards" and thus enable contacting and rotation of the magazine unit.
  • the magazine unit can be rotated by a drive that is completely decoupled from the ejector 30.
  • Figure 9 shows a sectional view through the lower section of the magazine unit 10.
  • the magazine unit has an inner cavity in which the slide locking element 40 is arranged.
  • a medicament portion is expelled by moving the slide 41 (or the slide blocking element 40) through an opening 14 in the feed section 15 into the latter.
  • the slide lock element in the embodiment described here is coupled via the coupling piece 35 to the slide drive 31, 32 arranged below the receiving trough, the bottom surface 13 has a gap through which the coupling piece can be moved.
  • the slide is completely guided in the feed section.
  • the lock is designed as an independent component, which can then, for example, also be introduced laterally into the feed section.
  • the ejector device 30 comprises a "push type" lifting magnet 31, 32, which has an immovable outer part 32 (the armature) and an inner movable component 31 (an electric coil).
  • the lifting magnet When the lifting magnet is activated, the armature 32 is moved into the electric coil, as a result of which the coupling piece 35 is moved radially outward.
  • This movement pushes the slide blocking element 40 through the opening 14 in the feed section 15, as a result of which the medicament portion 5 is expelled from the dispensing opening 12.
  • the lock 42 Due to the design of the slide lock element, the lock 42, which is formed by the upper wall of the bolt-like slide lock element 40, moves into the feed section 15 at the same time, which prevents any overlying medicament portions from sliding down.
  • FIGS 11a and 11b sectional views of the lower portion of the preferred embodiment of the supply and delivery station with active lifting magnets 31, 32 are shown.
  • a return spring 38 is tensioned, which moves the front section of the armature 32 back into the electric coil 31 when the magnet is deactivated.
  • the slide locking element 40 is partially moved into the feed section 15 so that the medicament portion 6 lying thereon cannot slip and possibly tilt.
  • the spring 38 which is tensioned when the lifting magnet 31, 32 is activated, pushes the armature 32 out of the electrical coil 31 of the lifting magnet when the lifting magnet is deactivated; At the same time, the slide lock element is also moved out of the feed section 15 into the cavity of the magazine unit due to the coupling via the coupling piece 35.
  • Figures 13a and 13b show the position of the Figures 11a, 11b and 12 from below, with Figure 13b the receiving tray 20 is omitted.
  • the solenoid is deactivated, the armature is pulled back into the electrocoil. Due to the coupling with the slide lock element, it is pulled out of the feed section.
  • the magazine unit can be rotated so that the "next full" feed section is rotated towards the slide blocking element. In the embodiment shown, this is done by the actuator 50, the two extensions 51 of which engage in the recesses 13 of the floor surfaces.

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP20162376.6A 2020-03-11 2020-03-11 Station de stockage et de distribution de médicaments Withdrawn EP3879503A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP20162376.6A EP3879503A1 (fr) 2020-03-11 2020-03-11 Station de stockage et de distribution de médicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20162376.6A EP3879503A1 (fr) 2020-03-11 2020-03-11 Station de stockage et de distribution de médicaments

Publications (1)

Publication Number Publication Date
EP3879503A1 true EP3879503A1 (fr) 2021-09-15

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EP20162376.6A Withdrawn EP3879503A1 (fr) 2020-03-11 2020-03-11 Station de stockage et de distribution de médicaments

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EP (1) EP3879503A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5152422A (en) * 1990-12-17 1992-10-06 Springer Reinhold A Medication dispenser
US5253782A (en) * 1992-05-20 1993-10-19 Paul A. Wiebel Article dispensing apparatus
US20020103573A1 (en) * 2001-01-31 2002-08-01 Fellows Eugene E. Article dispensing system
US20110290818A1 (en) * 2008-11-26 2011-12-01 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical dispenser and use thereof
WO2013034504A1 (fr) 2011-09-09 2013-03-14 Carefusion Switzerland 317 Sàrl Système et procédé de conditionnement de doses d'unités de médicament solide
EP2612645A2 (fr) * 2006-01-06 2013-07-10 AcelRx Pharmaceuticals, Inc. Dispositifs de stockage et de distribution de médicaments et systèmes comprenant ceux-ci

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5152422A (en) * 1990-12-17 1992-10-06 Springer Reinhold A Medication dispenser
US5253782A (en) * 1992-05-20 1993-10-19 Paul A. Wiebel Article dispensing apparatus
US20020103573A1 (en) * 2001-01-31 2002-08-01 Fellows Eugene E. Article dispensing system
EP2612645A2 (fr) * 2006-01-06 2013-07-10 AcelRx Pharmaceuticals, Inc. Dispositifs de stockage et de distribution de médicaments et systèmes comprenant ceux-ci
US20110290818A1 (en) * 2008-11-26 2011-12-01 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical dispenser and use thereof
WO2013034504A1 (fr) 2011-09-09 2013-03-14 Carefusion Switzerland 317 Sàrl Système et procédé de conditionnement de doses d'unités de médicament solide

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