EP3875028A3 - Biological fluid collection device - Google Patents

Biological fluid collection device Download PDF

Info

Publication number
EP3875028A3
EP3875028A3 EP21169174.6A EP21169174A EP3875028A3 EP 3875028 A3 EP3875028 A3 EP 3875028A3 EP 21169174 A EP21169174 A EP 21169174A EP 3875028 A3 EP3875028 A3 EP 3875028A3
Authority
EP
European Patent Office
Prior art keywords
biological fluid
collection device
flow
fluid collection
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP21169174.6A
Other languages
German (de)
French (fr)
Other versions
EP3875028B1 (en
EP3875028A2 (en
Inventor
Milan Ivosevic
Ryan W. MUTHARD
Alexander James BLAKE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of EP3875028A2 publication Critical patent/EP3875028A2/en
Publication of EP3875028A3 publication Critical patent/EP3875028A3/en
Application granted granted Critical
Publication of EP3875028B1 publication Critical patent/EP3875028B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150343Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/42Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/432Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
    • B01F25/4323Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa using elements provided with a plurality of channels or using a plurality of tubes which can either be placed between common spaces or collectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)

Abstract

A biological fluid collection device that produces a stabilized biological sample with head-to-tail uniformity through the capturing of a high concentration front and subsequent redistribution of the high concentration front throughout a biological fluid is disclosed. The biological fluid collection device includes an inline mixer used for head-to-tail mixing of a concentrated flow front. The mixing is achieved via a two-stage process. First, a front fraction of the flow is captured within a centered mixing chamber via capillary assisted flow action. Second, the captured front volume is then slowly released throughout a small exit hole and recombined with the rest of the flow volume that was diverted around the centered mixer chamber.
EP21169174.6A 2017-07-13 2018-07-06 Biological fluid collection device Active EP3875028B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762532111P 2017-07-13 2017-07-13
EP18747068.7A EP3651648B1 (en) 2017-07-13 2018-07-06 Biological fluid collection device
PCT/US2018/041027 WO2019014054A1 (en) 2017-07-13 2018-07-06 Biological fluid collection device

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP18747068.7A Division EP3651648B1 (en) 2017-07-13 2018-07-06 Biological fluid collection device

Publications (3)

Publication Number Publication Date
EP3875028A2 EP3875028A2 (en) 2021-09-08
EP3875028A3 true EP3875028A3 (en) 2021-10-06
EP3875028B1 EP3875028B1 (en) 2023-03-29

Family

ID=63047452

Family Applications (2)

Application Number Title Priority Date Filing Date
EP21169174.6A Active EP3875028B1 (en) 2017-07-13 2018-07-06 Biological fluid collection device
EP18747068.7A Active EP3651648B1 (en) 2017-07-13 2018-07-06 Biological fluid collection device

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP18747068.7A Active EP3651648B1 (en) 2017-07-13 2018-07-06 Biological fluid collection device

Country Status (11)

Country Link
US (1) US20210153793A1 (en)
EP (2) EP3875028B1 (en)
JP (1) JP7332572B2 (en)
CN (2) CN111031915B (en)
AU (2) AU2018301300B2 (en)
BR (1) BR112020000640A2 (en)
CA (1) CA3069447A1 (en)
ES (2) ES2870151T3 (en)
MX (1) MX2024004555A (en)
PL (1) PL3875028T3 (en)
WO (1) WO2019014054A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014172247A1 (en) * 2013-04-15 2014-10-23 Becton, Dickinson And Company Blood sampling transfer device
WO2014172234A1 (en) * 2013-04-15 2014-10-23 Becton, Dickinson And Company Biological fluid collection device and biological fluid separation and testing system
WO2014172233A1 (en) * 2013-04-15 2014-10-23 Becton, Dickinson And Company Biological fluid transfer device and biological fluid sampling system
US20160100783A1 (en) * 2014-10-14 2016-04-14 Becton, Dickinson And Company Blood Sample Management Using Open Cell Foam

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091802A (en) * 1976-02-17 1978-05-30 Eastman Kodak Company Vented liquid collection device
US4280496A (en) * 1979-02-16 1981-07-28 Baxter Travenol Laboratories, Inc. Phlebotomy needle assembly
CA1180734A (en) * 1981-04-21 1985-01-08 David R.P. Simpkins Atomizer
US5141501A (en) * 1990-05-21 1992-08-25 Vernay Laboratories, Inc. Suction metering and mixing device
US5968018A (en) 1996-10-30 1999-10-19 Cohesion Corporation Cell separation device and in-line orifice mixer system
JP2001161668A (en) 1999-12-07 2001-06-19 Terumo Corp Blood-collecting equipment
KR20060070536A (en) * 2003-08-05 2006-06-23 벡톤 디킨슨 앤드 컴퍼니 Device and methods for collection of biological fluid sample and treatment of selected components
EP2249701B1 (en) * 2008-03-05 2020-04-29 Becton, Dickinson and Company Capillary action collection container assembly
US7762715B2 (en) * 2008-10-27 2010-07-27 Cavitation Technologies, Inc. Cavitation generator
US9347086B2 (en) * 2009-04-03 2016-05-24 Integrated Nano-Technologies, Llc Method and system for sample preparation
CN101695447B (en) * 2009-10-30 2011-08-31 天津市百利康泰生物技术有限公司 Disposable hard connecting band collection container and anti-freezing vacuum blood taking needle of bleeding opening
CA2852090C (en) * 2011-10-20 2016-05-24 Becton, Dickinson And Company Mixing element for container assemblies
EP3068305A4 (en) * 2013-11-11 2017-06-21 Theranos, Inc. Methods and systems for a sample collection device with a novelty exterior
EP3939506A3 (en) 2014-10-14 2022-04-13 Becton, Dickinson and Company Blood sample management using open cell foam
AU2016229837B2 (en) * 2015-03-10 2018-05-24 Becton, Dickinson And Company Biological fluid micro-sample management device
CN108064149B (en) * 2015-06-19 2021-05-11 贝克顿·迪金森公司 Biological fluid collection device
EP3689238B1 (en) 2015-08-06 2021-09-29 Becton, Dickinson and Company Biological fluid collection device
CN205083491U (en) * 2015-08-20 2016-03-16 武汉唐济科技有限公司 Hemostix mixing device reaches from sufficient formula artery hemostix

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014172247A1 (en) * 2013-04-15 2014-10-23 Becton, Dickinson And Company Blood sampling transfer device
WO2014172234A1 (en) * 2013-04-15 2014-10-23 Becton, Dickinson And Company Biological fluid collection device and biological fluid separation and testing system
WO2014172233A1 (en) * 2013-04-15 2014-10-23 Becton, Dickinson And Company Biological fluid transfer device and biological fluid sampling system
US20160100783A1 (en) * 2014-10-14 2016-04-14 Becton, Dickinson And Company Blood Sample Management Using Open Cell Foam

Also Published As

Publication number Publication date
EP3875028B1 (en) 2023-03-29
PL3875028T3 (en) 2023-05-22
JP7332572B2 (en) 2023-08-23
AU2018301300B2 (en) 2024-03-21
ES2870151T3 (en) 2021-10-26
BR112020000640A2 (en) 2020-07-14
EP3651648B1 (en) 2021-04-21
MX2024004555A (en) 2024-04-30
AU2018301300A1 (en) 2020-02-13
CN209317471U (en) 2019-08-30
EP3651648A1 (en) 2020-05-20
AU2024203318A1 (en) 2024-06-06
US20210153793A1 (en) 2021-05-27
JP2020526763A (en) 2020-08-31
EP3875028A2 (en) 2021-09-08
WO2019014054A1 (en) 2019-01-17
CN111031915B (en) 2023-06-06
ES2942456T3 (en) 2023-06-01
CN111031915A (en) 2020-04-17
CA3069447A1 (en) 2019-01-17

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