EP3858963A1 - Détergent pour vaisselle à la main à dispersion d'aminoxyde à courte chaîne - Google Patents
Détergent pour vaisselle à la main à dispersion d'aminoxyde à courte chaîne Download PDFInfo
- Publication number
- EP3858963A1 EP3858963A1 EP20154849.2A EP20154849A EP3858963A1 EP 3858963 A1 EP3858963 A1 EP 3858963A1 EP 20154849 A EP20154849 A EP 20154849A EP 3858963 A1 EP3858963 A1 EP 3858963A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- weight
- composition according
- hand dishwashing
- amine oxides
- dishwashing composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 65
- 238000004851 dishwashing Methods 0.000 title claims abstract description 58
- 150000001412 amines Chemical class 0.000 title claims abstract description 44
- 238000009826 distribution Methods 0.000 title description 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 20
- 239000004094 surface-active agent Substances 0.000 claims abstract description 18
- 102000004190 Enzymes Human genes 0.000 claims description 35
- 108090000790 Enzymes Proteins 0.000 claims description 35
- -1 ether sulfates Chemical class 0.000 claims description 35
- 239000000654 additive Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000003945 anionic surfactant Substances 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 9
- 150000003839 salts Chemical class 0.000 claims description 8
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 7
- 239000004615 ingredient Substances 0.000 claims description 6
- 239000003960 organic solvent Substances 0.000 claims description 6
- 229920000642 polymer Polymers 0.000 claims description 5
- 239000012963 UV stabilizer Substances 0.000 claims description 4
- 150000008051 alkyl sulfates Chemical class 0.000 claims description 4
- 230000007797 corrosion Effects 0.000 claims description 4
- 238000005260 corrosion Methods 0.000 claims description 4
- 239000000645 desinfectant Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 239000000975 dye Substances 0.000 claims description 4
- 239000003112 inhibitor Substances 0.000 claims description 4
- 239000002304 perfume Substances 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 239000004519 grease Substances 0.000 claims description 3
- 239000006260 foam Substances 0.000 abstract description 9
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003599 detergent Substances 0.000 description 36
- 229940088598 enzyme Drugs 0.000 description 31
- 108091005804 Peptidases Proteins 0.000 description 23
- 239000004365 Protease Substances 0.000 description 23
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 18
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 17
- 108091005658 Basic proteases Proteins 0.000 description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- 125000004432 carbon atom Chemical group C* 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 8
- 150000002191 fatty alcohols Chemical class 0.000 description 8
- 239000002736 nonionic surfactant Substances 0.000 description 8
- 150000003254 radicals Chemical class 0.000 description 8
- 239000004711 α-olefin Substances 0.000 description 8
- 241000193422 Bacillus lentus Species 0.000 description 7
- 150000001298 alcohols Chemical class 0.000 description 7
- 239000011734 sodium Substances 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- 102000035195 Peptidases Human genes 0.000 description 6
- 150000001768 cations Chemical class 0.000 description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- 239000003925 fat Substances 0.000 description 6
- 239000000194 fatty acid Substances 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 108010020132 microbial serine proteinases Proteins 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 239000003381 stabilizer Substances 0.000 description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 5
- 108010065511 Amylases Proteins 0.000 description 5
- 102000013142 Amylases Human genes 0.000 description 5
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 5
- 108090000787 Subtilisin Proteins 0.000 description 5
- 235000019418 amylase Nutrition 0.000 description 5
- 235000014113 dietary fatty acids Nutrition 0.000 description 5
- 229930195729 fatty acid Natural products 0.000 description 5
- 150000004676 glycans Chemical class 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 5
- 150000003871 sulfonates Chemical class 0.000 description 5
- 239000002562 thickening agent Substances 0.000 description 5
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 4
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 4
- 239000004382 Amylase Substances 0.000 description 4
- 241000194110 Bacillus sp. (in: Bacteria) Species 0.000 description 4
- 101000740449 Bacillus subtilis (strain 168) Biotin/lipoyl attachment protein Proteins 0.000 description 4
- 108010059892 Cellulase Proteins 0.000 description 4
- 239000004435 Oxo alcohol Substances 0.000 description 4
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 4
- 229920002125 Sokalan® Polymers 0.000 description 4
- 229920002472 Starch Polymers 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000000470 constituent Substances 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 238000005238 degreasing Methods 0.000 description 4
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 4
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 4
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 4
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 4
- YBYRMVIVWMBXKQ-UHFFFAOYSA-N phenylmethanesulfonyl fluoride Chemical compound FS(=O)(=O)CC1=CC=CC=C1 YBYRMVIVWMBXKQ-UHFFFAOYSA-N 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 235000019698 starch Nutrition 0.000 description 4
- 239000003760 tallow Substances 0.000 description 4
- 229920002126 Acrylic acid copolymer Polymers 0.000 description 3
- 244000060011 Cocos nucifera Species 0.000 description 3
- 235000013162 Cocos nucifera Nutrition 0.000 description 3
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 102000004316 Oxidoreductases Human genes 0.000 description 3
- 108090000854 Oxidoreductases Proteins 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 229940106157 cellulase Drugs 0.000 description 3
- 239000002738 chelating agent Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- NPMRPDRLIHYOBW-UHFFFAOYSA-N 1-(2-butoxyethoxy)propan-2-ol Chemical compound CCCCOCCOCC(C)O NPMRPDRLIHYOBW-UHFFFAOYSA-N 0.000 description 2
- HLZKNKRTKFSKGZ-UHFFFAOYSA-N 1-Tetradecanol Natural products CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 2
- ARXJGSRGQADJSQ-UHFFFAOYSA-N 1-methoxypropan-2-ol Chemical compound COCC(C)O ARXJGSRGQADJSQ-UHFFFAOYSA-N 0.000 description 2
- FENFUOGYJVOCRY-UHFFFAOYSA-N 1-propoxypropan-2-ol Chemical compound CCCOCC(C)O FENFUOGYJVOCRY-UHFFFAOYSA-N 0.000 description 2
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 2
- QCAHUFWKIQLBNB-UHFFFAOYSA-N 3-(3-methoxypropoxy)propan-1-ol Chemical compound COCCCOCCCO QCAHUFWKIQLBNB-UHFFFAOYSA-N 0.000 description 2
- ATVJXMYDOSMEPO-UHFFFAOYSA-N 3-prop-2-enoxyprop-1-ene Chemical compound C=CCOCC=C ATVJXMYDOSMEPO-UHFFFAOYSA-N 0.000 description 2
- 102220560806 Acyl-CoA dehydrogenase family member 11_R99E_mutation Human genes 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 241000193375 Bacillus alcalophilus Species 0.000 description 2
- 241000193744 Bacillus amyloliquefaciens Species 0.000 description 2
- 241001328119 Bacillus gibsonii Species 0.000 description 2
- 241000194108 Bacillus licheniformis Species 0.000 description 2
- 101100400624 Caenorhabditis elegans mbr-1 gene Proteins 0.000 description 2
- 244000303965 Cyamopsis psoralioides Species 0.000 description 2
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 2
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 2
- 108010056079 Subtilisins Proteins 0.000 description 2
- 102000005158 Subtilisins Human genes 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 2
- 229910001413 alkali metal ion Inorganic materials 0.000 description 2
- 150000001342 alkaline earth metals Chemical class 0.000 description 2
- 125000005250 alkyl acrylate group Chemical group 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 108090000637 alpha-Amylases Proteins 0.000 description 2
- 150000001450 anions Chemical class 0.000 description 2
- CUFNKYGDVFVPHO-UHFFFAOYSA-N azulene Chemical compound C1=CC=CC2=CC=CC2=C1 CUFNKYGDVFVPHO-UHFFFAOYSA-N 0.000 description 2
- AFYNADDZULBEJA-UHFFFAOYSA-N bicinchoninic acid Chemical compound C1=CC=CC2=NC(C=3C=C(C4=CC=CC=C4N=3)C(=O)O)=CC(C(O)=O)=C21 AFYNADDZULBEJA-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229960003168 bronopol Drugs 0.000 description 2
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 229960000541 cetyl alcohol Drugs 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 229940071118 cumenesulfonate Drugs 0.000 description 2
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 108010002430 hemicellulase Proteins 0.000 description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N hexanedioic acid Natural products OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 2
- 229920001519 homopolymer Polymers 0.000 description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- 125000002960 margaryl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 229920003145 methacrylic acid copolymer Polymers 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 229940043348 myristyl alcohol Drugs 0.000 description 2
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N n-hexadecyl alcohol Natural products CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 125000001196 nonadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 125000002958 pentadecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 2
- SCVFZCLFOSHCOH-UHFFFAOYSA-M potassium acetate Chemical compound [K+].CC([O-])=O SCVFZCLFOSHCOH-UHFFFAOYSA-M 0.000 description 2
- 239000001508 potassium citrate Substances 0.000 description 2
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical class [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 229940012831 stearyl alcohol Drugs 0.000 description 2
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- HFVMEOPYDLEHBR-UHFFFAOYSA-N (2-fluorophenyl)-phenylmethanol Chemical class C=1C=CC=C(F)C=1C(O)C1=CC=CC=C1 HFVMEOPYDLEHBR-UHFFFAOYSA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- QWOZZTWBWQMEPD-UHFFFAOYSA-N 1-(2-ethoxypropoxy)propan-2-ol Chemical compound CCOC(C)COCC(C)O QWOZZTWBWQMEPD-UHFFFAOYSA-N 0.000 description 1
- JOLQKTGDSGKSKJ-UHFFFAOYSA-N 1-ethoxypropan-2-ol Chemical compound CCOCC(C)O JOLQKTGDSGKSKJ-UHFFFAOYSA-N 0.000 description 1
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical class CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- DBHODFSFBXJZNY-UHFFFAOYSA-N 2,4-dichlorobenzyl alcohol Chemical compound OCC1=CC=C(Cl)C=C1Cl DBHODFSFBXJZNY-UHFFFAOYSA-N 0.000 description 1
- OAYXUHPQHDHDDZ-UHFFFAOYSA-N 2-(2-butoxyethoxy)ethanol Chemical compound CCCCOCCOCCO OAYXUHPQHDHDDZ-UHFFFAOYSA-N 0.000 description 1
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 description 1
- COBPKKZHLDDMTB-UHFFFAOYSA-N 2-[2-(2-butoxyethoxy)ethoxy]ethanol Chemical compound CCCCOCCOCCOCCO COBPKKZHLDDMTB-UHFFFAOYSA-N 0.000 description 1
- WFSMVVDJSNMRAR-UHFFFAOYSA-N 2-[2-(2-ethoxyethoxy)ethoxy]ethanol Chemical compound CCOCCOCCOCCO WFSMVVDJSNMRAR-UHFFFAOYSA-N 0.000 description 1
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 description 1
- MUZDXNQOSGWMJJ-UHFFFAOYSA-N 2-methylprop-2-enoic acid;prop-2-enoic acid Chemical compound OC(=O)C=C.CC(=C)C(O)=O MUZDXNQOSGWMJJ-UHFFFAOYSA-N 0.000 description 1
- QWGRWMMWNDWRQN-UHFFFAOYSA-N 2-methylpropane-1,3-diol Chemical compound OCC(C)CO QWGRWMMWNDWRQN-UHFFFAOYSA-N 0.000 description 1
- JBVOQKNLGSOPNZ-UHFFFAOYSA-N 2-propan-2-ylbenzenesulfonic acid Chemical compound CC(C)C1=CC=CC=C1S(O)(=O)=O JBVOQKNLGSOPNZ-UHFFFAOYSA-N 0.000 description 1
- YEYKMVJDLWJFOA-UHFFFAOYSA-N 2-propoxyethanol Chemical compound CCCOCCO YEYKMVJDLWJFOA-UHFFFAOYSA-N 0.000 description 1
- SMWBSZMYOHHJDF-UHFFFAOYSA-N 3-methyl-3-(3-methylheptan-3-yloxy)heptane Chemical compound CCCCC(C)(CC)OC(C)(CC)CCCC SMWBSZMYOHHJDF-UHFFFAOYSA-N 0.000 description 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 101710184263 Alkaline serine protease Proteins 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 244000144927 Aloe barbadensis Species 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 241000416162 Astragalus gummifer Species 0.000 description 1
- 101710130006 Beta-glucanase Proteins 0.000 description 1
- 102100032487 Beta-mannosidase Human genes 0.000 description 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 108010084185 Cellulases Proteins 0.000 description 1
- 102000005575 Cellulases Human genes 0.000 description 1
- 108010008885 Cellulose 1,4-beta-Cellobiosidase Proteins 0.000 description 1
- 108010000659 Choline oxidase Proteins 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 241001440269 Cutina Species 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 108010059378 Endopeptidases Proteins 0.000 description 1
- 102000005593 Endopeptidases Human genes 0.000 description 1
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 description 1
- 229920002148 Gellan gum Polymers 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 241000208680 Hamamelis mollis Species 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 description 1
- 229920001612 Hydroxyethyl starch Polymers 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical class CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 1
- 108010059820 Polygalacturonase Proteins 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 108010022999 Serine Proteases Proteins 0.000 description 1
- 102000012479 Serine Proteases Human genes 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 101710135785 Subtilisin-like protease Proteins 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Chemical class OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003779 Vitamin B12 Natural products 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- ZZXDRXVIRVJQBT-UHFFFAOYSA-M Xylenesulfonate Chemical compound CC1=CC=CC(S([O-])(=O)=O)=C1C ZZXDRXVIRVJQBT-UHFFFAOYSA-M 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- RRUDCFGSUDOHDG-UHFFFAOYSA-N acetohydroxamic acid Chemical class CC(O)=NO RRUDCFGSUDOHDG-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 235000010419 agar Nutrition 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 102000004139 alpha-Amylases Human genes 0.000 description 1
- 229940024171 alpha-amylase Drugs 0.000 description 1
- 150000001413 amino acids Chemical group 0.000 description 1
- 229940025131 amylases Drugs 0.000 description 1
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Chemical class OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 description 1
- 239000010775 animal oil Substances 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 108010055059 beta-Mannosidase Proteins 0.000 description 1
- OHJMTUPIZMNBFR-UHFFFAOYSA-N biuret Chemical compound NC(=O)NC(N)=O OHJMTUPIZMNBFR-UHFFFAOYSA-N 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000008139 complexing agent Substances 0.000 description 1
- 239000011258 core-shell material Substances 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 150000001991 dicarboxylic acids Chemical class 0.000 description 1
- 229960004698 dichlorobenzyl alcohol Drugs 0.000 description 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 229940066758 endopeptidases Drugs 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 108010093305 exopolygalacturonase Proteins 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940100608 glycol distearate Drugs 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 229940059442 hemicellulase Drugs 0.000 description 1
- 229940051250 hexylene glycol Drugs 0.000 description 1
- 150000002430 hydrocarbons Chemical group 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229920013819 hydroxyethyl ethylcellulose Polymers 0.000 description 1
- 229940050526 hydroxyethylstarch Drugs 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000013038 irreversible inhibitor Substances 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000008297 liquid dosage form Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 229920003087 methylethyl cellulose Polymers 0.000 description 1
- 229940100573 methylpropanediol Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 238000006384 oligomerization reaction Methods 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 235000011056 potassium acetate Nutrition 0.000 description 1
- 235000011082 potassium citrates Nutrition 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 150000003138 primary alcohols Chemical class 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- JLGLQAWTXXGVEM-UHFFFAOYSA-N triethylene glycol monomethyl ether Chemical compound COCCOCCOCCO JLGLQAWTXXGVEM-UHFFFAOYSA-N 0.000 description 1
- 235000015870 tripotassium citrate Nutrition 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940118846 witch hazel Drugs 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940071104 xylenesulfonate Drugs 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/75—Amino oxides
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/83—Mixtures of non-ionic with anionic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0094—High foaming compositions
Definitions
- Dishwashing detergents in particular liquid dishwashing detergents for the manual cleaning of dishes, are known.
- consumers want improved cleaning power.
- the object of the present invention was therefore to provide new dishwashing detergents with good cleaning power, in particular good self-degreasing power and good foam volume.
- a dishwashing detergent comprising: at least one surfactant, the at least one surfactant being an amine oxide, and where the proportion of amine oxides, which have a C18 or longer residue is less than 10% based on the total weight of the amine oxides in the composition, more preferably less than 3%.
- compositions of this type in particular compositions which are essentially free of amine oxides which have a C18 or longer radical, in particular essentially C12 to C14, have particularly good fat-dissolving properties with good foam volume at the same time.
- Hand dishwashing composition wherein the proportion of amine oxides which have a C16 or more residue is less than 20%, more preferably less than 10%, based on the total weight of the amine oxides in the composition.
- Hand dishwashing composition the proportion of amine oxides which have a C12 residue being between 50 and 85% based on the total amount of amine oxide, preferably between 60 and 85%.
- Hand dishwashing composition the proportion of amine oxides having a C14 residue being between 20 and 35% based on the total amount of amine oxide.
- Hand dishwashing composition the proportion of amine oxides which have only C10 or smaller residues being less than 5% based on the total amount of amine oxide.
- a hand dishwashing composition wherein the amine oxide is present in a total amount of at least 0.5% by weight based on the total weight of the composition.
- a hand dishwashing composition wherein the surfactant system contains at least one anionic surfactant selected from ether sulfates, alkyl sulfates and mixtures thereof.
- a hand dishwashing composition wherein the anionic surfactant is present in an amount of at least 4% by weight based on the total weight of the composition.
- Hand dishwashing composition where the dishwashing composition has at least one additional ingredient selected from the group consisting of water, enzymes, organic solvents, enzymes, additives to improve the drainage and drying behavior, to adjust the viscosity and / or for stabilization, UV stabilizers, perfume, pearlescent agents, Contains colorants, corrosion inhibitors, preservatives, bitter substances, organic salts, disinfectants, structuring polymers, defoamers, encapsulated ingredients, pH adjusters and additives that improve or care for the skin.
- additional ingredient selected from the group consisting of water, enzymes, organic solvents, enzymes, additives to improve the drainage and drying behavior, to adjust the viscosity and / or for stabilization, UV stabilizers, perfume, pearlescent agents, Contains colorants, corrosion inhibitors, preservatives, bitter substances, organic salts, disinfectants, structuring polymers, defoamers, encapsulated ingredients, pH adjusters and additives that improve or care for the skin.
- compositions capable of dissolve fats, even without additional mechanical action, is called self-dissolving removal or self-degreasing power.
- self-dissolving removal In connection with hand dishwashing detergents, this is particularly the property of loosening grease from dishes, even without additional mechanical action from a sponge or brush.
- the present invention is also directed to the use of the dishwashing agent according to the invention for the manual cleaning of dishes.
- At least one refers to 1 or more, for example 2, 3, 4, 5, 6, 7, 8, 9 or more. In connection with constituents of the compounds described herein, this indication does not refer to the absolute amount of molecules, but to the type of constituent. “At least one surfactant” therefore means, for example, that only one type of surfactant compound or several different types of surfactant compounds can be contained without specifying the amount of the individual compounds.
- the expression “essentially free of” means that the respective compound can in principle be included, but is then present in an amount that does not impair the function of the other components.
- the property “essentially free of” a certain compound is therefore preferably a total weight of less than 0.1% by weight, more preferably less than 0.001% by weight, in particular free of this, based on the total weight of dishwashing detergent.
- molecular weight relates to the weight average molecular weight in g / mol, unless the number average molecular weight is explicitly mentioned.
- Molecular weights are preferably determined by GPC using polystyrene standards.
- fatty acids or fatty alcohols or their derivatives - unless otherwise stated - represent branched or unbranched carboxylic acids or alcohols or their derivatives with preferably 6 to 22 carbon atoms.
- the oxo alcohols or derivatives thereof obtainable, for example, by ROELEN's oxo synthesis, can also be used accordingly.
- components of the present agents are salts, they are preferably alkali metal or alkaline earth metal salts of the respective compounds, more preferably the alkali metal salts, in particular the sodium or potassium salts, most preferably sodium salts thereof.
- alkaline earth metals as counterions for monovalent Anions are mentioned, this means that the alkaline earth metal is of course only present in half the amount of substance - sufficient to balance the charge - as the anion.
- the substituent preferably replaces one or more H atoms.
- the dishwashing detergent according to the invention is preferably essentially free from cationic surfactants.
- the composition has at least one alkylbenzenesulfonate, which is preferably one C2-18 have alkyl radical. It is particularly preferably cumene sulfonate.
- alkylbenzenesulfonate is understood to mean only a benzene ring which is substituted by an alkyl radical and which also bears a sulfonate radical.
- the at least one alkylbenzenesulfonate is present in 0.5 to 50% by weight, preferably 0.5 to 30% by weight, particularly preferably 0.5 to 5% by weight, based on the total weight of the dishwashing detergent .
- the at least one fatty alcohol sulfate is preferably selected from C8-18 fatty alcohol sulfates, particularly preferred fatty alcohol sulfates are derived from C12-18 fatty alcohols, for example coconut fatty alcohol, tallow fatty alcohol, lauryl, myristyl, cetyl or stearyl alcohol. In particular, sodium lauryl sulfate is preferred.
- the at least one fatty alcohol sulfate is contained in 0.5 to 45% by weight, preferably 0.5 to 40% by weight, more preferably 3 to 15% by weight, based on the total weight of the dishwashing detergent.
- the at least one amine oxide is a compound which has the formula R1R2R3NO, where each R1, R2 and R3, independently of the others, is an optionally substituted, for example hydroxy-substituted, C1-C30 hydrocarbon chain.
- Amine oxides used with particular preference are those in which R1 is C10-C16 alkyl and R2 and R3 are each independently C1-C4 alkyl, in particular C10-C16 alkyldimethylamine oxides.
- Exemplary representatives of suitable amine oxides are N-cocoalkyl-N, N-dimethylamine oxide and N-tallow alkyl-N, N-dihydroxyethylamine oxide.
- the at least one amine oxide is preferably selected from C12-16 amine oxides, particularly preferably from low-chain C12-14 alkyldimethylamine oxides.
- the at least one amine oxide is contained in 0.1 to 20% by weight, preferably 0.3 to 10% by weight, more preferably 0.5 to 3% by weight, based on the total weight of the dishwashing detergent .
- the at least one further anionic, nonionic or zwitterionic surfactant is preferably in 0.1 to 45% by weight, preferably 0.5 to 40% by weight, more preferably in 1 to 25% by weight, based on the total weight of the dishwashing detergent.
- Suitable further surfactants are, for example, alpha-olefin sulfonates.
- Preferred alpha olefin sulfonates are selected from C10-20 alpha olefin sulfonates, more preferably from linear C10-20 alpha olefin sulfonates. In particular, it is selected from C12-14 alpha olefin sulfonates; most preferably it is a linear C12-14 alpha olefin sulfonate.
- the at least one alpha-olefin sulfonate is preferably contained in 2.5 to 45% by weight, more preferably 3 to 30% by weight, particularly preferably 5 to 25% by weight, based on the total weight of the dishwashing detergent.
- a suitable alpha-olefin sulfonate is commercially available, for example, under the trade name Bio-Terge® AS-40 from Stephan.
- the at least one further anionic surfactant is selected from ether sulfates, alkyl sulfates and mixtures thereof.
- Preferred ether sulfates are those of the formula (I) R1-O- (AO) n-SO3- X + (I).
- R1 represents a linear or branched, substituted or unsubstituted alkyl radical, preferably a linear, unsubstituted alkyl radical, particularly preferably a fatty alcohol radical.
- Preferred radicals R1 are selected from decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl radicals and mixtures thereof, the representatives with an even number of carbon atoms are preferred.
- radicals R1 are derived from C12-C18 fatty alcohols, for example from coconut fatty alcohol, tallow fatty alcohol, lauryl, myristyl, cetyl or stearyl alcohol or from C10-C20 oxo alcohols.
- X stands for a monovalent cation or the nth part of an n-valent cation, preferred are the alkali metal ions, including Na + or K +, Na + being extremely preferred. Further cations X + can be selected from NH4 +, 1 ⁇ 2 Zn2 +, 1 ⁇ 2 Mg2 +, 1 ⁇ 2 Ca2 +, 1 ⁇ 2 Mn2 +, and mixtures thereof.
- AO stands for an ethylene oxide (EO) or propylene oxide (PO) group, preferably an ethylene oxide group.
- EO ethylene oxide
- PO propylene oxide
- the index n stands for an integer from 1 to 50, preferably from 1 to 20 and in particular from 2 to 10. Very particularly preferably n stands for the numbers 2, 3, 4, 5, 6, 7 or 8.
- alkyl sulfates which are not derived from fatty alcohols, of the formula R2-O-SO3- X + (II).
- R2 stands for a linear or branched, substituted or unsubstituted alkyl radical, preferably a linear, unsubstituted alkyl radical, particularly preferably a fatty alcohol radical.
- Preferred radicals R2 are selected from decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl radicals and mixtures thereof, the representatives with an even number of carbon atoms are preferred. They are particularly preferably derived from C10-20 oxo alcohols.
- X stands for a monovalent cation or the nth part of an n-valent cation, preferred are the alkali metal ions, including Na + or K +, Na + being extremely preferred. Further cations X + can be selected from NH4 +, 1 ⁇ 2 Zn2 +, 1 ⁇ 2 Mg2 +, 1 ⁇ 2 Ca2 +, 1 ⁇ 2 Mn2 +, and mixtures thereof.
- the at least one further nonionic surfactant is in 0.1 to 20% by weight, preferably 0.5 to 10% by weight, more preferably 1 to 8% by weight, based on the total weight of the dishwashing detergent contain.
- nonionic surfactants known for dishwashing detergents are suitable as further nonionic surfactants.
- the at least one further nonionic surfactant is selected from alkoxylated fatty acid alkyl esters, polyhydroxy fatty acid amides, alkyl glycosides and alkoxylated alcohols and mixtures thereof.
- nonionic surfactants are alkoxylated, preferably ethoxylated or ethoxylated and propoxylated fatty acid alkyl esters, preferably with 1 to 4 carbon atoms in the alkyl chain.
- surfactants are the polyhydroxy fatty acid amides known as PHFA.
- alkyl glycosides of the general formula RO (G) x in which R corresponds to a primary straight-chain or methyl-branched, in particular methyl-branched in the 2-position, aliphatic radical with 8 to 22, preferably 12 to 18 carbon atoms and G is the symbol for a glycose unit with 5 or 6 carbon atoms, preferably for glucose.
- the degree of oligomerization x which indicates the distribution of monoglycosides and oligoglycosides, is any number between 1 and 10; x is preferably 1.2 to 1.4.
- the further nonionic surfactants are selected from the group of alkoxylated alcohols.
- the nonionic surfactants used are preferably alkoxylated, advantageously ethoxylated, in particular primary alcohols with preferably 8 to 18 carbon atoms and an average of 1 to 12 moles of ethylene oxide (EO) or propylene oxide (PO) per mole of alcohol, in which the alcohol radical is linear or preferably in 2 -Position can be methyl-branched or can contain linear and methyl-branched radicals in the mixture, as they are usually present in oxo alcohol radicals.
- EO ethylene oxide
- PO propylene oxide
- alcohol ethoxylates with linear radicals of alcohols of native origin with 12 to 18 carbon atoms for example from coconut, palm, tallow or oleyl alcohol, and an average of 2 to 8 moles of EO per mole of alcohol are preferred.
- the preferred ethoxylated alcohols include, for example, C12-14 alcohols with 3 EO or 4 EO, C8-11 alcohol with 7 EO, C13-15 alcohols with 3 EO, 5 EO, 7 EO or 8 EO, C12-18- Alcohols with 3 EO, 5 EO or 7 EO and mixtures of these, such as mixtures of C12-14 alcohol with 3 EO and C12-18 alcohol with 5 EO.
- the total amount of surfactants i.e. the surfactant system, based on the weight of the agent, is 2.5 to 70% by weight, preferably 5 to 60% by weight, even more preferably 6 to 50% by weight.
- the dishwashing detergent according to the present invention can also contain at least one additional ingredient selected from the group consisting of water, organic solvents, enzymes, additives to improve the drainage and drying behavior, to adjust the viscosity and / or for stabilization, UV stabilizers, perfume, Pearlescent agents, dyes, corrosion inhibitors, preservatives, bitter substances, organic salts, disinfectants, structuring polymers, defoamers, encapsulated ingredients, pH adjusters and additives that improve or care for the skin.
- at least one additional ingredient selected from the group consisting of water, organic solvents, enzymes, additives to improve the drainage and drying behavior, to adjust the viscosity and / or for stabilization, UV stabilizers, perfume, Pearlescent agents, dyes, corrosion inhibitors, preservatives, bitter substances, organic salts, disinfectants, structuring polymers, defoamers, encapsulated ingredients, pH adjusters and additives that improve or care for the skin.
- the dishwashing detergents according to the present invention are liquid and contain water as the main solvent, i.e. they are aqueous dishwashing detergents.
- the water content of the aqueous agent according to the invention is usually 15 to 90% by weight, preferably 20 to 60% by weight.
- organic solvents can be added to the dishwashing detergent.
- Suitable organic solvents include monohydric or polyhydric alcohols, alkanolamines or glycol ethers, provided they are miscible with water in the specified concentration range.
- the solvents are preferably selected from ethanol, n-propanol, i-propanol, butanols, glycol, propanediol, butanediol, methylpropanediol, glycerol, diglycol, propyl diglycol, butyl diglycol, hexylene glycol, ethylene glycol methyl ether, ethylene glycol ethyl ether, ethylene glycol ether, ethylene glycol propyl ether, Diethylene glycol ethyl ether, propylene glycol methyl ether, propylene glycol ethyl ether, propylene glycol propyl ether, dipropylene glycol monomethyl ether, dipropylene glycol mono
- the dishwashing detergents described herein can also contain at least one enzyme, preferably a protease.
- the proteases used are preferably alkaline serine proteases. They act as unspecific endopeptidases, that is, they hydrolyze any acid amide bonds that are inside peptides or proteins, thereby breaking down protein-containing soiling on the items to be cleaned. Their pH optimum is usually in the clearly alkaline range.
- subtilisin 309 examples of the proteases that can be used in the agents described herein are subtilisin 309 or functional fragments / variants thereof and variants of the alkaline protease from Bacillus lentus or variants thereof.
- Subtilisin 309 is sold under the trade name Savinase® by Novozymes A / S, Bagsvaerd, Denmark.
- Optimized enzyme variants of the subtilisin 309 from Bacillus lentus are available from Novozymes under the trade names Blaze® and Ovozyme®, which represent a preferred embodiment of the invention.
- the protease variants under the name BLAP® are derived from the alkaline protease from Bacillus lentus DSM 5483.
- Protease variants are particularly preferred here which have at least one mutation at R99 compared to the BLAP wt (wild type) enzyme, in the count according to BLAP wt, in particular R99E or R99D, particularly preferred is R99E, and optionally additionally at least one or two , preferably all three of the amino acid substitutions S3T, V4I and V199I, particularly preferred are the BLAP variants as they are in SeqID No 4 or 5 of the WO 2014/177430 are described.
- the enzymes to be used can also be packaged together with accompanying substances, for example from fermentation.
- the enzymes are preferably used as liquid enzyme formulation (s).
- the proteases are not provided in the form of the pure protein but rather in the form of stabilized, storable and transportable preparations.
- These ready-made preparations include, for example, those by granulation, extrusion or Solid preparations obtained by lyophilization or, in particular in the case of liquid or gel-form agents, solutions of the enzymes, advantageously as concentrated as possible, with little water and / or mixed with stabilizers or other auxiliaries.
- the enzymes can be encapsulated both for the solid and for the liquid dosage form, for example by spray drying or extrusion of the enzyme solution together with a preferably natural polymer or in the form of capsules, for example those in which the enzymes are enclosed as in a solidified gel or in those of the core-shell type, in which an enzyme-containing core is coated with a protective layer which is impermeable to water, air and / or chemicals.
- Additional active ingredients for example stabilizers, emulsifiers, pigments, bleaches or dyes, can also be applied in superimposed layers.
- Such capsules are applied by methods known per se, for example by shaking or rolling granulation or in fluid-bed processes. Such granules are advantageously low in dust, for example through the application of polymeric film-forming agents, and due to the coating are stable in storage.
- Dishwashing detergents according to the invention can alternatively or in addition to the at least one protease contain one or more further enzymes, in particular from the following group: amylases, hemicellulases, cellulases, lipases and oxidoreductases.
- the dishwashing detergent according to the invention particularly preferably also contains at least one amylase.
- the amylase (s) is preferably an ⁇ -amylase.
- the hemicellulase is preferably a ⁇ -glucanase, a pectinase, a pullulanase and / or a mannanase.
- the cellulase is preferably a cellulase mixture or a one-component cellulase, preferably or predominantly an endoglucanase and / or a cellobiohydrolase.
- the oxidoreductase is preferably an oxidase, in particular a choline oxidase, or a perhydrolase.
- the enzymes mentioned can all be formulated as described above for the proteases.
- the at least one enzyme preferably the at least one protease and / or at least one amylase in an amount of 0.01-1.6% by weight, preferably 0.05-1.2% by weight based on the total weight of the dishwashing detergent.
- the enzyme (s) can be pre-formulated with enzyme stabilizers in an enzyme composition.
- the enzyme protein usually only forms a fraction of the total weight of the enzyme preparation.
- Enzyme preparations used with preference contain between 0.1 and 40% by weight, preferably between 0.2 and 30% by weight, particularly preferably between 0.4 and 20% by weight and in particular between 0.8 and 10% by weight % of the enzyme protein.
- an enzyme stabilizer can be included in the enzyme composition in an amount of 0.05-35% by weight, preferably 0.05-10% by weight, based on the total weight.
- This enzyme composition can then be used in dishwashing detergents according to the invention, specifically in amounts which lead to the final concentrations specified above in the dishwashing detergent. Suitable enzyme stabilizers are known in the prior art.
- the agent according to the invention can accordingly additionally have one or more enzyme stabilizers.
- the protein concentration can be determined with the aid of known methods, for example the BCA method (bicinchoninic acid; 2,2'-bichinolyl-4,4'-dicarboxylic acid) or the biuret method.
- the active protein concentration is determined by titrating the active centers using a suitable irreversible inhibitor (for proteases, for example, phenylmethylsulfonyl fluoride (PMSF)) and determining the residual activity (cf. M. Bender et al., J. Am. Chem. Soc. 88, 24 (1966), pp. 5890-5913 ).
- a suitable irreversible inhibitor for proteases, for example, phenylmethylsulfonyl fluoride (PMSF)
- the agent according to the invention can contain one or more additives from the group of polymers and builders, usually in an amount of 0.001 to 5% by weight, preferably 0.01 to 4 % By weight, in particular 0.1 to 3% by weight, particularly preferably 0.2 to 2% by weight, extremely preferably 0.5 to 1.5% by weight, for example 1% by weight.
- Polymeric thickeners for the purposes of the present invention are the polycarboxylates, preferably homopolymers and copolymers of acrylic acid, in particular acrylic acid copolymers such as acrylic acid-methacrylic acid copolymers, and the polysaccharides, in particular heteropolysaccharides, and other conventional thickening polymers.
- Suitable polysaccharides or heteropolysaccharides are the polysaccharide gums, for example gum arabic, agar, alginates, carrageenans and their salts, guar, guaran, tragacanth, gellan, ramsan, dextran or xanthan and their derivatives, e.g. propoxylated guar, as well as their mixtures.
- Other polysaccharide thickeners such as starches or cellulose derivatives, can be used as an alternative, but preferably in addition to a polysaccharide gum, for example starches of various origins and starch derivatives, e.g.
- hydroxyethyl starch starch phosphate esters or starch acetates, or carboxymethyl cellulose or its sodium salt, methyl, ethyl, hydroxyethyl, Hydroxypropyl, hydroxypropyl methyl or hydroxyethyl methyl cellulose or cellulose acetate.
- Acrylic acid polymers suitable as polymeric thickeners are, for example, high molecular weight homopolymers of acrylic acid (INCI Carbomer) crosslinked with a polyalkenyl polyether, in particular an allyl ether of sucrose, pentaerythritol or propylene, which are also referred to as carboxyvinyl polymers.
- a polyalkenyl polyether in particular an allyl ether of sucrose, pentaerythritol or propylene, which are also referred to as carboxyvinyl polymers.
- Particularly suitable polymeric thickeners are, however, the following acrylic acid copolymers: (i) Copolymers of two or more monomers from the group of acrylic acid, methacrylic acid and their simple esters, preferably formed with C1 4 alkanols (INCI Acrylates Copolymers), which include, for example, the copolymers of methacrylic acid, butyl acrylate and methyl methacrylate (CAS 25035 69 2) or of butyl acrylate and methyl methacrylate (CAS 25852 37 3); (ii) crosslinked high molecular weight acrylic acid copolymers, to which, for example, the copolymers of C10-30 alkyl acrylates crosslinked with an allyl ether of sucrose or pentaerythritol with one or more monomers from the group of acrylic acid, methacrylic acid and their simple esters, preferably formed with C1 4 alkanols ( INCI Acrylates / C10-30 Alkyl Acrylate Crosspolymer
- the content of polymeric thickener is usually not more than 8% by weight, preferably between 0.1 and 7% by weight, particularly preferably between 0.5 and 6% by weight, in particular between 1 and 5% by weight and extremely preferably between 1.5 and 4% by weight, for example between 2 and 2.5% by weight, based on the total weight of the dishwashing detergent.
- one or more dicarboxylic acids and / or their salts can be added, in particular a composition of sodium salts of adipic, succinic and glutaric acid, such as those available under the trade name Sokalan® DSC is. They are advantageously used in amounts of 0.1 to 8% by weight, preferably 0.5 to 7% by weight, in particular 1.3 to 6% by weight and particularly preferably 2 to 4% by weight, based on the total weight of the dishwashing detergent.
- the agent according to the invention is preferably free from dicarboxylic acid (salts).
- auxiliaries and additives especially UV stabilizers, perfume, pearlescent agents (INCI Opacifying Agents; for example glycol distearate, e.g. Cutina® AGS from Cognis, or mixtures containing this, e.g.
- the Euperlane® from Cognis dyes, corrosion inhibitors, preservatives (for example the technical 2-bromo-2-nitropropane-1,3-diol (CAS 52-51-7), also known as bronopol (CAS 52-51-7), for example as Myacide® BT or as Boots Bronopol BT is commercially available from Boots) or Acticide MBR 1 or Acticide CMB 2, organic salts, disinfectants, pH adjusters and additives that improve or care for the skin (e.g.
- dermatologically active substances such as vitamin A, vitamin B2, vitamin B12, vitamin C, vitamin E, D panthenol, sericerin, collagen partial hydrolyzate, various vegetable protein partial hydrolyzates, protein hydrolyzate-fatty acid condensate ate, liposomes, cholesterol, vegetable and animal oils such as lecithin, soybean oil, etc., plant extracts such as aloe vera, azulene, witch hazel extracts, algae extracts, etc., allantoin, AHA complexes, glycerol, urea, quaternized hydroxyethyl cellulose), in quantities of usually not more than 8 wt .-%, based on the total weight of the dishwashing detergent.
- Na xylene sulfonate can be used as a viscosity regulating additive.
- the pH value of the agent according to the invention can be adjusted by means of conventional pH regulators, for example acids such as mineral acids or citric acid and / or alkalis such as sodium or potassium hydroxide, with a range from 4 to 9 - especially if hand tolerance is desired.
- acids such as mineral acids or citric acid
- alkalis such as sodium or potassium hydroxide
- the agent according to the invention can contain one or more buffer substances (INCI buffering agents), usually in amounts of 0.001 to 5% by weight, preferably 0.005 to 3% by weight, in particular 0 0.1 to 2% by weight, particularly preferably 0.05 to 1% by weight, extremely preferably 0.1 to 0.5% by weight, for example 0.2% by weight.
- buffer substances that are also complexing agents or even chelating agents (chelators, INCI chelating agents).
- Particularly preferred buffer substances are citric acid or the citrates, in particular the sodium and potassium citrates, for example trisodium citrate ⁇ 2 H2O and tripotassium citrate ⁇ H2O.
- Table 1 shows the following experimental compositions: V1 E1 E2 100 100 100 100 % as % active % telq % active % telq % active % telq Water, soft 100 54.98 54.98 54.98 54.98 54.98 54.98 54.98 54.98 54.98 54.98 FAEOS-Na C12-14 2EO 70% 70 10.40 14.86 10.40 14.86 10.40 14.86 Amine oxides, C12-C18 alkyldimethyl 30th 2,600 8.67 1,820 6.07 0 0 Amine oxides, C12-C14 alkyldimethyl 30th 0 0 0.780 2.60 2,600 8.67 Na-cumene sulfonate 40 1,000 2.50 1,000 2.50 1,000 2.50 1,000 2.50 Acticide MBR 1 100 0.100 0.10 0.100 0.10 0.100 0.10 Potassium acetate 70% solution 70 0.140 0.20 0.140 0.20 0.140 0.20 Sodium hydroxide 50% 50 Citric acid solution 50 0.075 0.15 0.075 0.15 0.0
- the self-degreasing power (“self degreasing"), ie the self-releasing removal of fat in particular without additional mechanical action, for example by means of a sponge or a brush, was tested in the above examples to the effect that dishes soiled with fats can be used with the above compositions without additional mechanical action was brought into contact.
- the property of dissolving fats from dishes was shown, even without additional mechanical action by a sponge or a brush, preferably by the composition E1 and more preferably by E2. It has thus been shown that a shortening of the amine oxide chain length results in improved self-fat dissolving power.
- the foam volume was determined at 20 ° C and at 30 ° C.
- the compositions were stirred for 10 seconds to 150 seconds at 2000 rpm and a corresponding characteristic number proportional to the foam volume was determined.
- Table 2 [sec], 2000 rpm E2, 20 ° C V1, 20 ° C E2, 30 ° C V1, 30 ° C 1.x 10 177 161 163 153 2.x 10 264 242 253 224 3.x 10 355 310 339 292 4.x 10 433 378 420 341 5.x 10 488 435 482 391 6.x 10 518 470 526 427 7.x 10 535 495 555 457 8.x 10 544 509 578 477 9.x 10 552 517 591 492 10.x 10 559 523 614 506 11.x 10 561 523 629 518 12.x 10 562 527 659 529 13.x 10 567 530 673 539 14.x 10 572 531 681 549 15.x 10 573 530 6
- Table 3 shows examples of C12 to C14 amine oxide chain length distributions: Table 3: Chain length R3 C10 and lower 2% C12 68% C14 25% C16 5% C18 and larger 0%
- Table 4 shows examples of C12 to C18 amine oxide chain length distributions: Table 4: Chain length R3 C10 and lower 5% C12 42% C14 23% C16 17% C18 and larger 13%
- Amine oxide distributions can fluctuate within certain limits.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20154849.2A EP3858963A1 (fr) | 2020-01-31 | 2020-01-31 | Détergent pour vaisselle à la main à dispersion d'aminoxyde à courte chaîne |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20154849.2A EP3858963A1 (fr) | 2020-01-31 | 2020-01-31 | Détergent pour vaisselle à la main à dispersion d'aminoxyde à courte chaîne |
Publications (1)
Publication Number | Publication Date |
---|---|
EP3858963A1 true EP3858963A1 (fr) | 2021-08-04 |
Family
ID=69423149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20154849.2A Pending EP3858963A1 (fr) | 2020-01-31 | 2020-01-31 | Détergent pour vaisselle à la main à dispersion d'aminoxyde à courte chaîne |
Country Status (1)
Country | Link |
---|---|
EP (1) | EP3858963A1 (fr) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69901703T2 (de) * | 1998-06-02 | 2003-01-30 | Procter & Gamble | Geschirrspülmittelzusammentsetzungen enthaltend organische diamine |
WO2014177430A1 (fr) | 2013-04-30 | 2014-11-06 | Henkel Ag & Co. Kgaa | Produit détergent contenant des protéases |
WO2015183611A1 (fr) * | 2014-05-29 | 2015-12-03 | The Procter & Gamble Company | Taux d'agent tensioactif optimisé pour une meilleure sensation de rinçage |
WO2017153564A1 (fr) * | 2016-03-11 | 2017-09-14 | Henkel Ag & Co. Kgaa | Produit de nettoyage contenant un aminoxyde |
EP3456803A1 (fr) * | 2017-09-15 | 2019-03-20 | The Procter & Gamble Company | Composition de nettoyage liquide pour laver la vaisselle à la main |
EP3578630A1 (fr) * | 2018-06-04 | 2019-12-11 | The Procter & Gamble Company | Composition de détergent liquide |
-
2020
- 2020-01-31 EP EP20154849.2A patent/EP3858963A1/fr active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69901703T2 (de) * | 1998-06-02 | 2003-01-30 | Procter & Gamble | Geschirrspülmittelzusammentsetzungen enthaltend organische diamine |
WO2014177430A1 (fr) | 2013-04-30 | 2014-11-06 | Henkel Ag & Co. Kgaa | Produit détergent contenant des protéases |
WO2015183611A1 (fr) * | 2014-05-29 | 2015-12-03 | The Procter & Gamble Company | Taux d'agent tensioactif optimisé pour une meilleure sensation de rinçage |
WO2017153564A1 (fr) * | 2016-03-11 | 2017-09-14 | Henkel Ag & Co. Kgaa | Produit de nettoyage contenant un aminoxyde |
EP3456803A1 (fr) * | 2017-09-15 | 2019-03-20 | The Procter & Gamble Company | Composition de nettoyage liquide pour laver la vaisselle à la main |
EP3578630A1 (fr) * | 2018-06-04 | 2019-12-11 | The Procter & Gamble Company | Composition de détergent liquide |
Non-Patent Citations (2)
Title |
---|
HANS SANDERSON ET AL: "High Production Volume Chemical Amine Oxides [C 8 -C 20 ] Category Environmental Risk Assessment", RISK ANALYSIS, vol. 29, no. 6, 1 June 2009 (2009-06-01), US, pages 857 - 867, XP055707739, ISSN: 0272-4332, DOI: 10.1111/j.1539-6924.2009.01208.x * |
M. BENDER ET AL., J. AM. CHEM. SOC., vol. 88, no. 24, 1966, pages 5890 - 5913 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE102019207891A1 (de) | Schaumstabilisierung durch spezifisches Tensidgemisch | |
DE102019207890A1 (de) | Schaumstabilisierung durch spezifisches Tensidgemisch | |
EP3670637A1 (fr) | Régulation de la viscosité dans les agents de rinçage à la main | |
WO2017162646A1 (fr) | Produit de nettoyage contenant de la protéase et de l'amylase | |
WO2017153565A1 (fr) | Stabilisation d'enzymes dans des produits de nettoyage contenant des enzymes | |
DE102019203801A1 (de) | Handgeschirrspülmittel umfassend Glutaminsäure Komplexbildner | |
EP3858963A1 (fr) | Détergent pour vaisselle à la main à dispersion d'aminoxyde à courte chaîne | |
EP4098727B1 (fr) | Détergent à viscosité modifiée pour le lavage manuel de la vaisselle | |
WO2018086847A1 (fr) | Amylase pour applications de produits de lavage et de nettoyage | |
DE102020215131A1 (de) | Verwendung eines Geschirrspülmittels zur Erhöhung der Dosiergenauigkeit | |
DE102021206648A1 (de) | Handgeschirrspülmittel mit Katalase und weiterem Enzym | |
WO2017153564A1 (fr) | Produit de nettoyage contenant un aminoxyde | |
EP4047077A1 (fr) | Détergent stable pour lavage manuel de la vaisselle comprenant de la catalase | |
WO2020239543A1 (fr) | Augmentation de la solubilité grâce à un mélange spécifique de tensio-actifs | |
WO2020169680A1 (fr) | Détergents à vaisselle contenant de l'alpha-oléfine sulfonate | |
EP4098728A1 (fr) | Procédé de fabrication de détergent pour le lavage manuel de la vaisselle à viscosité modifiée | |
DE102021203331A1 (de) | Verwendung viskositätsregulierter Handgeschirrspülmittel bei tiefen Temperaturen | |
DE102021201250A1 (de) | Keimentfernende Handgeschirrspülmittel | |
DE102019219832A1 (de) | Selbstentfettendes Handgeschirrspülmittel | |
DE102019107448A1 (de) | Schaumstabilisierung durch spezifisches Tensidgemisch | |
EP4047078A1 (fr) | Détergent conservateur pour lavage manuel de la vaisselle comprenant de la catalase | |
EP3786270A1 (fr) | Composition de détergent pour le lavage manuel de la vaisselle comprenant un agent de blanchiment | |
DE102020215685A1 (de) | Handgeschirrspülkapsel | |
EP3712236A1 (fr) | Amélioration de la solubilité de divers systèmes tensioactifs par application de phosphonates | |
EP3786273A1 (fr) | Détergent pour le lavage manuel de la vaisselle comprenant un agent de blanchiment |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20200131 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230530 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |