EP3840831A4 - Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment - Google Patents

Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment Download PDF

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Publication number
EP3840831A4
EP3840831A4 EP19852909.1A EP19852909A EP3840831A4 EP 3840831 A4 EP3840831 A4 EP 3840831A4 EP 19852909 A EP19852909 A EP 19852909A EP 3840831 A4 EP3840831 A4 EP 3840831A4
Authority
EP
European Patent Office
Prior art keywords
treatment
inflammatory bowel
bowel disease
high risk
identifying individuals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19852909.1A
Other languages
German (de)
French (fr)
Other versions
EP3840831A1 (en
Inventor
Bruce R. YACYSHYN
Mary E. Yacyshyn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3840831A1 publication Critical patent/EP3840831A1/en
Publication of EP3840831A4 publication Critical patent/EP3840831A4/en
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Evolutionary Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Data Mining & Analysis (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
EP19852909.1A 2018-08-21 2019-08-20 Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment Pending EP3840831A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862720468P 2018-08-21 2018-08-21
PCT/US2019/047231 WO2020041287A1 (en) 2018-08-21 2019-08-20 Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment

Publications (2)

Publication Number Publication Date
EP3840831A1 EP3840831A1 (en) 2021-06-30
EP3840831A4 true EP3840831A4 (en) 2022-05-11

Family

ID=69591310

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19852909.1A Pending EP3840831A4 (en) 2018-08-21 2019-08-20 Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment

Country Status (4)

Country Link
EP (1) EP3840831A4 (en)
AU (1) AU2019325238A1 (en)
CA (1) CA3108719A1 (en)
WO (1) WO2020041287A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110045476A1 (en) * 2009-04-14 2011-02-24 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics
US20120171672A1 (en) * 2009-04-14 2012-07-05 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7879553B2 (en) * 2008-03-14 2011-02-01 Exagen Diagnostics, Inc. Biomarkers for inflammatory bowel disease and irritable bowel syndrome
WO2012037199A2 (en) * 2010-09-14 2012-03-22 The Johns Hopkins University Methods for diagnosis and prognosis of inflammatory bowel disease using cytokine profiles
AU2012325798B2 (en) * 2011-10-21 2015-11-26 Société des Produits Nestlé S.A. Methods for improving inflammatory bowel disease diagnosis
WO2014182689A1 (en) * 2013-05-06 2014-11-13 Yacyshyn Bruce R Method of using biomarkers in predicting inflammatory bowel disease
US10295527B2 (en) * 2016-03-14 2019-05-21 Bruce Yacyshyn Process and system for predicting responders and non-responders to mesalamine treatment of ulcerative colitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110045476A1 (en) * 2009-04-14 2011-02-24 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics
US20120171672A1 (en) * 2009-04-14 2012-07-05 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MORTENSEN JOACHIM HØG ET AL: "Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis", JOURNAL OF CROHN'S AND COLITIS, vol. 9, no. 10, 18 July 2015 (2015-07-18), NL, pages 863 - 872, XP055907377, ISSN: 1873-9946, Retrieved from the Internet <URL:https://watermark.silverchair.com/jjv123.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuAwggLcBgkqhkiG9w0BBwagggLNMIICyQIBADCCAsIGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMzlRioibu2SG_AjSQAgEQgIICkychmHOXI4bIXNIYHuD5tuNT__UAlhuhR8PZjY7gI7o-RWwR4EpdLYCym14YZC_DExTXJtjw0prrXSo88LeV4tO1llfYC> DOI: 10.1093/ecco-jcc/jjv123 *

Also Published As

Publication number Publication date
WO2020041287A1 (en) 2020-02-27
CA3108719A1 (en) 2020-02-27
AU2019325238A1 (en) 2021-03-18
EP3840831A1 (en) 2021-06-30

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