EP3784672A4 - Tablet formulations comprising metformin and sitagliptin - Google Patents

Tablet formulations comprising metformin and sitagliptin Download PDF

Info

Publication number
EP3784672A4
EP3784672A4 EP19834733.8A EP19834733A EP3784672A4 EP 3784672 A4 EP3784672 A4 EP 3784672A4 EP 19834733 A EP19834733 A EP 19834733A EP 3784672 A4 EP3784672 A4 EP 3784672A4
Authority
EP
European Patent Office
Prior art keywords
sitagliptin
metformin
tablet formulations
formulations
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19834733.8A
Other languages
German (de)
French (fr)
Other versions
EP3784672A2 (en
Inventor
Ali Turkyilmaz
Seval Ataman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanovel Ilac Sanayi ve Ticaret AS
Original Assignee
Sanovel Ilac Sanayi ve Ticaret AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanovel Ilac Sanayi ve Ticaret AS filed Critical Sanovel Ilac Sanayi ve Ticaret AS
Publication of EP3784672A2 publication Critical patent/EP3784672A2/en
Publication of EP3784672A4 publication Critical patent/EP3784672A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP19834733.8A 2018-04-27 2019-03-25 Tablet formulations comprising metformin and sitagliptin Pending EP3784672A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR201806019 2018-04-27
PCT/TR2019/050190 WO2020013777A2 (en) 2018-04-27 2019-03-25 Tablet formulations comprising metformin and sitagliptin

Publications (2)

Publication Number Publication Date
EP3784672A2 EP3784672A2 (en) 2021-03-03
EP3784672A4 true EP3784672A4 (en) 2022-03-30

Family

ID=69141601

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19834733.8A Pending EP3784672A4 (en) 2018-04-27 2019-03-25 Tablet formulations comprising metformin and sitagliptin

Country Status (2)

Country Link
EP (1) EP3784672A4 (en)
WO (1) WO2020013777A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022074664A1 (en) * 2020-10-05 2022-04-14 V-Ensure Pharma Technologies Private Limited An immediate release composition of sitagliptin hydrochloride
KR20230009020A (en) * 2021-07-08 2023-01-17 한미약품 주식회사 A composite tablet containing sitagliptin, dapagliflozin and metformin
CN114010612B (en) * 2021-11-24 2022-06-28 上海普康药业有限公司 Sitagliptin and metformin double-layer sustained release tablet and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100323011A1 (en) * 2008-03-04 2010-12-23 Nazaneen Pourkavoos Pharmaceutical compositions of a combination of metformin and a dipeptidyl peptidase-iv inhibitor
EP3731828A2 (en) * 2017-12-28 2020-11-04 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Tablet formulations comprising metformin and sitagliptin processed with hot-melt extrusion

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080064701A1 (en) * 2007-04-24 2008-03-13 Ramesh Sesha Anti-diabetic combinations
BRPI0814299B8 (en) 2007-07-19 2021-05-25 Takeda Pharmaceuticals Co solid preparation comprising alogliptin and metformin hydrochloride, use of a solid preparation, and, methods for stabilizing a compound in a solid preparation, and for producing a solid preparation
PE20140960A1 (en) 2008-04-03 2014-08-15 Boehringer Ingelheim Int FORMULATIONS INVOLVING A DPP4 INHIBITOR
WO2013110085A1 (en) 2012-01-20 2013-07-25 Handa Pharmaceuticals, Llc Oral dosage forms for delivering metformin and sitagliptin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100323011A1 (en) * 2008-03-04 2010-12-23 Nazaneen Pourkavoos Pharmaceutical compositions of a combination of metformin and a dipeptidyl peptidase-iv inhibitor
EP3731828A2 (en) * 2017-12-28 2020-11-04 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Tablet formulations comprising metformin and sitagliptin processed with hot-melt extrusion

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020013777A2 *

Also Published As

Publication number Publication date
EP3784672A2 (en) 2021-03-03
WO2020013777A2 (en) 2020-01-16
WO2020013777A3 (en) 2020-04-09

Similar Documents

Publication Publication Date Title
EP3706741A4 (en) Pharmaceutical composition and use thereof
EP3849983A4 (en) Triazolo-pyrimidine compounds and uses thereof
EP3904351A4 (en) Fak inhibitor and drug combination thereof
EP3802562A4 (en) New pharmaceutical use
EP3735463A4 (en) Cytotoxicity-inducing therapeutic agent
EP3760632A4 (en) Pyrazolopyrimidine derivative and use thereof
EP4051246A4 (en) Bilayer tablet formulations comprising dapagliflozin and metformin
EP3981769A4 (en) Pyrrolopyrimidine compound and use thereof
EP3737676A4 (en) Acetal compounds and therapeutic uses thereof
EP3784672A4 (en) Tablet formulations comprising metformin and sitagliptin
IL284994A (en) Pyrrolopyrimidine derivative and use thereof
EP3687501A4 (en) Iniparib formulations and uses thereof
EP3760616A4 (en) 4-methyldihydropyrimidinone compound and medicinal use thereof
EP3731837A4 (en) The combination comprising linagliptin and metformin
EP3886820B8 (en) Capsule formulations
EP3697411A4 (en) Novel pharmaceutical composition and use thereof
EP3793561A4 (en) Antiviral drug compounds and composition thereof
EP3755376A4 (en) Formulations containing mucin-affecting proteases
EP3716766A4 (en) Benzoxaborole compounds and formulations thereof
EP4031122A4 (en) Effervescent tablet formulations comprising dapagliflozin and metformin
EP3497080A4 (en) Pharmaceutical formulations and their use
EP3999056A4 (en) Pharmaceutical combination and use thereof
EP3851108A4 (en) Borate-based drug and use thereof
EP3901146A4 (en) Phenylpyrrolidine compound and use thereof
EP3817744A4 (en) Ivosidenib forms and pharmaceutical compositions

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20201027

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

TPAC Observations filed by third parties

Free format text: ORIGINAL CODE: EPIDOSNTIPA

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Free format text: PREVIOUS MAIN CLASS: C07D0487040000

Ipc: A61K0009200000

A4 Supplementary search report drawn up and despatched

Effective date: 20220224

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/4985 20060101ALI20220220BHEP

Ipc: A61K 31/155 20060101ALI20220220BHEP

Ipc: A61K 9/24 20060101ALI20220220BHEP

Ipc: A61K 9/20 20060101AFI20220220BHEP

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230708