EP3768379A1

EP3768379A1 - Equipment designed to stimulate and optimize the bio-molecular and cellular reorganization

Info

Publication number: EP3768379A1
Application number: EP18719418.8A
Authority: EP
Inventors: Saverio Giangregorio
Original assignee: Novatech Solutions SA
Current assignee: Novatech Solutions SA
Priority date: 2018-03-20
Filing date: 2018-03-20
Publication date: 2021-01-27
Also published as: WO2019178704A1

Abstract

The appliance in question is designed to stimulate and optimise the bio-molecular and cellular reorganisation of any kind of organic tissue, in such a way as to rebalance the natural defences that exist in an individual or in any kind of cellular system. The appliance contains components which are able to generate fields of appropriate radio frequencies, with continuous programmed modulation in sequential order, to create treatment energies in accordance with a determined code. These resonate with the natural sub-atomic, atomic, molecular and cellular oscillators of the individual or any kind of cellular system, to rebalance the metabolic and ion interchange functions. In this way, the various elements find themselves in a situation of equilibrium, due to the correct symbiosis that exists between the stimulator element and the organism.

Description

EQUIPMENT DESIGNED TO STIMULATE AND OPTIMISE THE BIO-MOLECULAR AND CELLULAR REORGANIZATION OF ANY KIND OF ORGANIC TISSUE

PRESENTATION OF THE INVENTION

Equipment designed to stimulate and optimize the bio-molecular and cellular reorganization of any kind of organic tissue.

This invention is a piece of equipment designed to stimulate the natural defences of any individual or cellular system. It is used to generate radio frequency fields at overlapping levels in a sequential order, with programmed modulations, with a view to recreating the various biochemical elements that exist in a living organism.

The appliance is also used to normalize all the cellular properties, including reproduction, respiration, assimilation, growth excitability and mobility.

The type of energy produced by the appliance forms a group of communication codes with the molecular and cellular systems. This technique of combinations forms an optimum bioelectrical synergism (cell + electrical oscillator) which backs up the cellular functions to bring about a general improvement in all the physiological activities.

Reason for the application

The applicant is unaware of any other patents with the same features, The applicant are not known other patents, except the one belonging to the same applicant (PCT WO 01/70334 Al), with the same features but with different circuit concepts. In addition, the applicant claims that there are similar applications but not to this level and with various usage concepts.

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Feuilles de remplacement (REGLE 26 PCT) The same designation "Regenotherapy" proposal, exclusively, from studies by the applicant.

Below, they are going to expose and analyze all cases of application and related technical and practical relations of the system.

Introduction

Scientific principle of the device

The device was created to generate modulations of radio frequencies at overlapping levels and in sequential order, with programmed modulations geared towards creating special treatment energies that stimulate the natural defenses existing in a living being to the maximum.

These fields, with the features referred to above, represent linguistic codes for communication with the organized sub-atomic, atomic, molecular and cellular systems, which in the final analysis have to be considered as a group of natural oscillators that obey the same laws as electrical oscillators applied to partial and total blocks, but within the same space and at the same time.

This technique of combinations creates an optimum bioelectrical synergism to back up the cellular functions, in this way obtaining a general improvement and normalization of all the physiological activities.

Technical and scientific report

Living matter has various levels of organization and variable dimensions. The first and most simple level of matter is the atom, which forms the basis of all the other levels of organization.

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Feuilles de remplacement (REGLE 26 PCT) At the level immediately above this, we can see that the atoms of the various elements present in nature tend to aggregate spontaneously in molecules, most of which are simple and made up of a small quantity of associated elements. It is only in living beings that we can see the formation of molecules that are often large and complex, with carbon chains of various lengths as their central point The carbon molecules of living organisms interact with each other in an ordered manner, to create new and higher levels of organization. On the basis of this first series of scientifically known concepts, we can go on to state that the appliance in question will make it possible for determined phenomena of bio-structural reorganization in all organic tissues to take place. The principle of communication among the cells develops through the acquisition of all the signals that reach the cell from the outside.

These are captured by the "molecular antennae" (the receptors or receptor cells). But, in the same way as with electromagnetic television waves, a transport and conversion system for the signal is necessary if an organizational response is to be obtained (the picture). In this way, the cells have developed a system to convert the signals arriving from the outside.

The transport, conversion and amplification of the signal received enable the tissue cell or cells to respond in a suitable way, in accordance with requirements.

We are already aware that there may be signals that are able to penetrate the cell (steroid hormones) where the receptors are located. In this case the acquisition of the cell takes place directly.

In the case of information that is unable to overcome the barrier of the cellular membrane (water soluble hormones), more complex mechanisms are necessary.

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Feuilles de remplacement (REGLE 26 PCT) The internal signals are transported by a series of small molecules known as "second messengers". In molecular terms, the transmission process for this signal depends on a series of proteins contained in the cellular membrane. Each of these transmits an item of information which induces an alteration in the shape, and consequently in the function, of the adjacent protein. At a certain point, the information reaches small molecules or even the organic ions present in the cytoplasm. These are the second messengers, whose distribution ensures that the signal spreads and amplifies rapidly throughout the cell.

The number of second messengers is limited. This means that the routes inside the cell for the transmission of the signals are universal, and also able to regulate an enormous variety of physiological and biochemical processes. Two main routes for the re-transmission of the signals are known. One of these uses a nucleotide as second messenger, while the other uses a combination of second messengers, including calcium ions (Ca2+) and other substances deriving from the components of the cellular membrane (phospholipids). The two routes have many things in common. In both of them, the initial composition, that is, the receptor molecule present on the cell surface, transmits the information through the plasma membrane and inside the cell itself, by means of a family of proteins that operate as transducers, known as G proteins. In both routes, the G proteins activate an amplifier enzyme which is always found in the cellular membrane.

This transforms the precursor molecules into second messengers which spread the signals in the cell. The final stages in the process are also similar. The second messengers induce a number of cellular proteins to modify their structure, producing as a result the activation or inhibition of the function of a determined protein. The second messengers therefore turn on or off the switches that regulate the protein activity, creating different conditions inside the cell.

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Feuilles de remplacement (REGLE 26 PCT) These conditions will determine the type of response that the cell will give to the signal received from the outside. In most cases, the second messenger is linked to a component part of an enzymatic protein, inducing the activity of the component that brings about the enzyme functions.

In some cases, there are receptors that cross the membrane and present part of the protein inside the cell that performs enzymatic activities similar to those described above. In this case, the signal transport and amplification mechanisms are not necessary, while the switch is turned on and off by the signal bond itself. As an alternative to these signal transmission methods, the action of the receptors which have bound the messenger may consist in the selective opening of small pores or specific channels for certain ions (such as calcium) present on the surface of the cellular membrane.

In the case of calcium (Ca2+), the entrance of the cell has the same effect as the presence of the second messengers. Most of the information conveyed by these chains of messengers ends up going to the nucleus of the cell, where it regulates or induces the expression of the genes.

The messages carried by the soluble molecules in the fats (steroid hormones) which are able to cross the membrane also arrive at the nucleus. The receptors for these hormones, as we saw above, are found in the cytoplasm. They are proteins whose shape is modified by the bond with the molecule of the signal. The modified protein enters the nucleus and becomes able to form a bond with the DNA, the large molecule that conserves the genetic information at precise points where it is used to regulate the activation of the genes present in the point where the bond has been created.

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Feuilles de remplacement (REGLE 26 PCT) This effect is known as the primary response. In other cases, there is a secondary response, that is, the products of the primary response may have as their function the activation of the other genes, by forming a bond with the DNA, by amplifying and varying the response.

The response to the steroid hormones, which is similar to that for all the hormones, depends on the nature of the hormone and that of the target cell. It would appear, in fact, that the same receptors for a determined hormone present in different types of cell give different responses, because they link different points of the DNA in a specific manner. Naturally, to ensure that there is no biological unbalance in the cell and organism that would overflow into physiological conditions, the entire system of signals has to be finely regulated.

One method of regulation is that of the indirect signal system, in which the negative retroaction mechanisms, which are fields of continuous, controlled frequencies, dampen the primary signals. Another way to regulate the response is to act on the receptors. After the water soluble hormones link up with their receptors on the surface of the target cells, the cells often swallow these up by endocytosis and destroy them, In this way, as there are no longer any receptors or their number has been reduced, the capacity to respond to the hormone also ceases.

In other cases, the receptor is "internalized" by endocytosis and kept in vesicles, for later remounting on the cellular membrane.

At times the receptor remains on the surface of the cell, but modifies its formation in such a way that it is no longer able to bind the hormone, or else it does bind it but without transmitting the signal into the cell.

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Feuilles de remplacement (REGLE 26 PCT) All these phenomena last for a certain number of hours, whereupon the cell returns to normal conditions and can once again receive signals. Yet another way of regulating the response is to destroy the second messengers and reduce the amplification of the signal. This takes place by means of specific enzymes within the space of a few minutes.

The same may also occur for the primary signals (hormones of a protein nature), which are eliminated by lytic enzymes. On the basis of the above explanation, we can clearly see how complex and sophisticated the network of signals exchanged among the signals has to be if the organism is to remain in perfect biological balance. If only one of these systems should go out of control, for some reason linked to the regulation, the effects produced are much greater than the initial alteration. The situation is similar to that of a television that, due to a breakdown, can no longer be switched off or adjusted. Something similar could take place in the cell which, due to a second messenger, can no longer be regulated.

Circuit description

Introduction

The purpose of the appliance is to generate a series of radio frequency signals modulated and controlled in breadth, for therapeutic and preventive purposes. One or more independent channels, are provided for this purpose, and in the case of more, each settable at will in its operating parameters. The start and stop the generation of R. F. They are also independent. To achieve the performance characteristics, attributed to the equipment, microcontrollers, composed of a single electronic card are set and programmed, which are housed on a general mother board. On the motherboard is placed, also, the power supply that provides the voltages necessary for the operation of the circuits.

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Feuilles de remplacement (REGLE 26 PCT) Function blocks

The equipment can be divided into four functional blocks: mother board. On the mother board are placed:

- The power supply that generates the voltages necessary to the operation

- The connection of the channel cards connectors

- The output connectors to the R.F.

- The connections between the various internal equipment services.

A channel group consists of the following tabs:

- The support sheet of the keys and display behind the front panel

- The main board, referred to as mother-board, which serves as an interface between the microcontroller and the various commands

The card which comprises a group of more channels, consists in the multiple of the specified channels, with characteristics of autonomy in each their function.

Power supply

The power supply generates three continuous voltages: + 5V, + 12V, + 24V. The AC voltage from the filter adapter, placed in the rear panel, is connected to a transformer.

On the secondary it is connected to the diode bridge that rectifies the voltage and the two filter capacitors; the DC voltage, the so obtained is stabilized by means of a linear regulator of the type LM7805 and an output capacitor.

Board / front panel LEDs and buttons

On board are located:

- 12 LEDs with corresponding supply resistance

- 12 keys with the networks resisted the pull-up, SIL

The board is connected to the mother board by a flexible flat cable 10 poles, for each independent channel, with their end connectors.

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Feuilles de remplacement (REGLE 26 PCT) Board with microcontroller: MOTHER BOARD

On board are located:

- 1 integrated type PIC 16F84A of Microchip, with microcontroller function. One for each channel.

The microcontroller allows the management of the settings of the operational parameters and receiving parametric data, also monitors the START and STOP, the generation of all types of delay timers needed to the different emission characteristics.

Two direct out of the microcontroller (not memory mapped), control the modulation of the generators of the R.F. The microcontroller also counts the emission time, managing the remaining time and providing an audible alert signal, at the end of the application.

On board they are located also:

- 2 transistors for the modulator of the R.F.

- 1 transistor for the generation of the R.F.

The transistor T3 acts as a oscillator / generator of R.F. and it is controlled by the two transistors T1 and T2, which modulate the emission ON / OFF mode, to gain the desired pulse trains.

The oscillation frequency (carrier) is determined by the constants: LI, L2, C8.

The detection circuit of the R.F. produced, it is obtained by the diode Dl, and the capacitor Cll, which operate as envelope detectors; Furthermore, the presence of R.F. active the circuit that turns on the indication led on the issue in R. F.

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Feuilles de remplacement (REGLE 26 PCT) CONTENTS

PAGE 1 - PRESENTATION OF THE INVENTION

PAGE 1 - REASON FOR THE APPLICATION

PAGE 2 - INTRODUCTION - Scientific principle of the device

PAGE 2 - TECHNICAL AND SCIENTIFIC REPORT

PAGE 7 - CIRCUIT DESCRIPTION

PAGE 10 - CLAIMS

PAGE 12 - SUMMARY

PAGE 14 - CONTENTS/ APPENDICES

Appendices:

Fig. 1 - Terminal for therapy - 600 x 200 mm

Fig. 2 Terminal type A for therapy 310 x 120 mm

Fig. 3 - Terminal type B for therapy - 287 x 90 mm

Fig. 4 - Terminal type C for therapy - 285 x 80 mm

Fig. 5 - Block Fig. of the equipment

Fig. 6 - Keys - Mother board - power supply

Fig. 7 - Front panel and led

Fig. 8 - Connection cable for terminal of therapy

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Feuilles de remplacement (REGLE 26 PCT)

Claims

Claims:

1. Appliance designed to stimulate and normalize the natural defenses in an individual or in any cellular system, made up of components that generate fields of specific radio frequencies, at overlapping levels and in sequential order, with programmed modulation, to create treatment energies in line with determined codes that resonate with the natural sub-atomic, atomic, molecular and cellular oscillators of the individual or any type of cellular system to rebalance the metabolism.

2. An appliance as described in claim 1 with a multiple generation system at controlled breadth, made up of a microcontroller for the handling of the operating parameters for the entire system, two transistors (T01 and T02) that act as sequential modulators from which the impulse trains required are obtained, a single transistor (T03) that represents the oscillating and R.F. generating part, the integrated circuit (IC02) that operates as the R.F. signal detector, the integrated circuit used as interface between the microprocessor and the modulating part of the R.F. circuit, an integrated circuit (IC03) that operates as the decoder of the logical and analogue address bus, and a further integrated circuit (IC04) which is used to create the serial interface of the microprocessor with the data received.

3. An appliance as described in claim 2, with an integrated circuit (IC02) located at the microprocessor input (IC01), pin 8, used to reset the microprocessor, and a quartz (XT01), which determines the microprocessor operating clock, connected to pins 9 and 10 of the integrated circuit

4. An accessory to the appliance as described in claim 3, essential for the therapy, defined as a terminal or antenna, with the following features: internal dimensions: (pure circuit part) 155 x 545 mm.

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Feuilles de remplacement (REGLE 26 PCT)

5. The distances among the six series of tracks that make up the circuit are 12 mm each. There are 13 parallel tracks, and the distance between one track and another is 0.5 mm, the same as the thickness. The structure consists of two sheets of polyester, with dimensions 600 x 200 mm, inside which a high concentration silver-treated ink circuit develops over the dimensions described in this claim.

6. An accessory to the appliance as described in claim 4, consisting of the connection system between the therapy terminal and the appliance itself, in the form of a coaxial cable terminating in a R.F. connector and, at the other end, two automatic buttons in a die cast non-conducting material, separated by a fork in a die cast material that forms a double deflection.

7. An accessory to the appliance as described in claim 5, consisting of a therapeutic terminal (A) known as a dental mask, with the following features: dimensions of the most distant points 310 x 120 mm, with wraparound shape for the face and an opening for the mouth. The structure consists of two sheets of profiled polyester with a circuit inside that emits the appropriate radio frequencies, traced in ink with a high percentage of silver (70%), with 70 tracks each 3 mm wide, arranged at a distance of 3 mm from each other. The ends of the tracks terminate in two automatic buttons for the connection with the appliance.

8. An accessory to the appliance as described in claim 6, consisting of a therapeutic terminal (B) known as a dental mask, with the following features: dimensions of the most distant points 287 x 90 mm, with wraparound shape for the face and an opening for the mouth. The structure consists of two sheets of profiled polyester with a circuit inside that emits the appropriate radio frequencies, traced in ink with a high percentage of silver (70%), with 56 tracks each 3.5 mm wide, arranged at a distance of 2.5 mm from each other. The ends of the tracks terminate in two automatic buttons for the connection with the appliance.

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Feuilles de remplacement (REGLE 26 PCT) An accessory to the appliance as described in claim 7, consisting of a therapeutic terminal (C) known as a dental mask, with the following features: dimensions of the most distant points 285 x 80 mm, with wraparound shape for the face and an opening for the mouth. The structure consists of two sheets of profiled polyester with a circuit inside that emits the appropriate radio frequencies, traced in ink with a high percentage of silver (70%), with 40 tracks each 4 mm wide, arranged at a distance of 4 mm from each other. The ends of the tracks terminate in two automatic buttons for the connection with the appliance.

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Feuilles de remplacement (REGLE 26 PCT)