EP3746091A4 - Cholestyramine formulations and methods of use - Google Patents

Cholestyramine formulations and methods of use Download PDF

Info

Publication number
EP3746091A4
EP3746091A4 EP19746690.7A EP19746690A EP3746091A4 EP 3746091 A4 EP3746091 A4 EP 3746091A4 EP 19746690 A EP19746690 A EP 19746690A EP 3746091 A4 EP3746091 A4 EP 3746091A4
Authority
EP
European Patent Office
Prior art keywords
methods
cholestyramine
formulations
cholestyramine formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19746690.7A
Other languages
German (de)
French (fr)
Other versions
EP3746091A1 (en
Inventor
Sophie TANGUAY
Smita Debnath
Mustapha KANDIL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pmsci Research And Development Inc
Original Assignee
Pharmascience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmascience Inc filed Critical Pharmascience Inc
Publication of EP3746091A1 publication Critical patent/EP3746091A1/en
Publication of EP3746091A4 publication Critical patent/EP3746091A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/34Monomers containing two or more unsaturated aliphatic radicals
    • C08F212/36Divinylbenzene

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19746690.7A 2018-01-30 2019-01-30 Cholestyramine formulations and methods of use Withdrawn EP3746091A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862623895P 2018-01-30 2018-01-30
PCT/CA2019/050116 WO2019148278A1 (en) 2018-01-30 2019-01-30 Cholestyramine formulations and methods of use

Publications (2)

Publication Number Publication Date
EP3746091A1 EP3746091A1 (en) 2020-12-09
EP3746091A4 true EP3746091A4 (en) 2021-10-06

Family

ID=67477895

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19746690.7A Withdrawn EP3746091A4 (en) 2018-01-30 2019-01-30 Cholestyramine formulations and methods of use

Country Status (4)

Country Link
US (1) US20210077413A1 (en)
EP (1) EP3746091A4 (en)
CA (1) CA3089742A1 (en)
WO (1) WO2019148278A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023013878A (en) 2021-05-25 2023-12-08 Evonik Operations Gmbh Hard-shell capsule with influx prevention of gastric fluids.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080311161A1 (en) * 2005-10-11 2008-12-18 Jonathan David Gass Compositions and Methods for Enhanced Gastrointestinal Stability of Oligopeptides and Polypeptides
WO2010079343A2 (en) * 2009-01-09 2010-07-15 Cambridge Enterprise Limited Formulations of viable cells for oral delivery
US20170224720A1 (en) * 2016-02-09 2017-08-10 Albireo Ab Oral cholestyramine formulation and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI241195B (en) * 2000-04-10 2005-10-11 Shionogi & Co Preventive agent for bile acidic diarrhea
CN104023718B (en) * 2011-10-28 2017-04-05 鲁美纳医药公司 For treating the bile acid recycling inhibitors of high cholemia and cholestatic liver disease
RU2750937C2 (en) * 2016-02-09 2021-07-06 Альбирео Аб Oral cholestyramine composition and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080311161A1 (en) * 2005-10-11 2008-12-18 Jonathan David Gass Compositions and Methods for Enhanced Gastrointestinal Stability of Oligopeptides and Polypeptides
WO2010079343A2 (en) * 2009-01-09 2010-07-15 Cambridge Enterprise Limited Formulations of viable cells for oral delivery
US20170224720A1 (en) * 2016-02-09 2017-08-10 Albireo Ab Oral cholestyramine formulation and use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2019148278A1 *

Also Published As

Publication number Publication date
WO2019148278A1 (en) 2019-08-08
CA3089742A1 (en) 2019-08-08
EP3746091A1 (en) 2020-12-09
US20210077413A1 (en) 2021-03-18

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Ipc: A61K 9/48 20060101ALI20210831BHEP

Ipc: A61K 31/785 20060101AFI20210831BHEP

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