EP3740549A1 - Formulation de décontamination de surface - Google Patents

Formulation de décontamination de surface

Info

Publication number
EP3740549A1
EP3740549A1 EP19741692.8A EP19741692A EP3740549A1 EP 3740549 A1 EP3740549 A1 EP 3740549A1 EP 19741692 A EP19741692 A EP 19741692A EP 3740549 A1 EP3740549 A1 EP 3740549A1
Authority
EP
European Patent Office
Prior art keywords
decontamination
sub
chemical
formulation
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19741692.8A
Other languages
German (de)
English (en)
Other versions
EP3740549A4 (fr
Inventor
Matthew A. BLUHM
Brian STARBUCK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Decon7 Systems Inc
Original Assignee
Decon7 Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2018/037817 external-priority patent/WO2018232281A1/fr
Application filed by Decon7 Systems Inc filed Critical Decon7 Systems Inc
Publication of EP3740549A1 publication Critical patent/EP3740549A1/fr
Publication of EP3740549A4 publication Critical patent/EP3740549A4/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/08—Alkali metal chlorides; Alkaline earth metal chlorides
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/38—Cationic compounds
    • C11D1/62—Quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39—Organic or inorganic per-compounds
    • C11D3/3942—Inorganic per-compounds

Definitions

  • a harmful substance may penetrate deeply into the reticulated grain structures of microscopic surfaces, making it difficult to displace. Simply using water or other solvent may not present the appropriate physiochemical environment sufficient to overcome the forces holding or shielding the substance in place.
  • Embodiments of the invention describe an enhanced chemical formulation and manner of practice administering two predicate patented products (DF-200 and SSDX- 12) designed for the decontamination, disinfection and renewal of surfaces exposed to chemical, biological, toxic industrial contaminants and residues. These two products are standalone treatments for decontamination strategies. The combinations of the two in concert with one another presents a unique approach to decontamination and disinfection strategies.
  • SSDX-12 is a high potency decontamination soap specifically used for the safe decontamination of air craft.
  • SSDX-12 was required to demonstrate resistance to corrosion on aircraft metal alloys and sensitive equipment.
  • the product was also required to remove residues of chemical weapons down to an acceptable standard. While the product is demonstrably effective at treating the targeted surfaces, the challenge of remediating the now dissolved and mobile chemical agents remained. In many situations it is simply unacceptable to rinse the treatment off into the environment.
  • D7 formula (hereinafter“D7” or“D7 formula”) is a high potency
  • D7 decontamination/disinfection agent used to treat surfaces contaminated with bacteria, viruses, mold, mildew, toxic industrial chemicals, chemical weapons and other pathogenic and harmful agents.
  • D7 is able to promote the rapid chemical remediation of these threats by virtue of its unique ability to solubilize normally water insoluble targets and expose them to chemical oxidation directly or in the realm of a self assembled micellular structure embodied in the formula.
  • D7 formula extends the technology to include both oxidation reactions and reducing reactions. Additionally, D7 incorporates the treatment for toxic industrial chemicals. It also is the first reference to a bleaching activator.
  • D7 expands into the area of mold, disinfection and
  • D7 expands on the chemical landscape for DF-200. Additionally it incorporates data for rates of reaction against various toxic agents. It is also an improvement of the original DF-100 relative to performance against mustard agents in regard to reaction time and specificity. In one embodiment, D7 also integrates different bleaching activators.
  • SSDX-12 is designed to achieve a safe, environmentally benign, low regret
  • the offending substance can be hydraulically removed or rendered hydraulically vulnerable.
  • the SSDX-12 may include a cleaning composition such as a C. sub.8-22 alkyl dimethylamine oxide surfactant, a C. sub.6-12 alkyl dimethylamine oxide surfactant, a C. sub.8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant, and a C. sub.12-14 secondary alcohol ethoxylate surfactant.
  • the C. sub.8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant includes from 0 to about 20 ethoxylate groups per C. sub.8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant molecule.
  • the C. sub.12-14 secondary alcohol ethoxylate surfactant includes from about 14 to about 16 ethoxylate groups per C. sub.12-14 secondary alcohol ethoxylate surfactant molecule.
  • a cleaning composition for cleaning exterior surfaces of a vehicle includes from about 0.1% to about 5% by weight of a C. sub.8-16 alkyl dimethylamine oxide surfactant, from about 0.1% to about 5% by weight of a C. sub.6-10 alkyl dimethylamine oxide surfactant, from about 0.1% to about 5% by weight of a C. sub.10-14 alkyl polyethylene glycol sorbitan fatty ester surfactant, and from about 0.1% to about 5% by weight of a C. sub.12-14 secondary alcohol ethoxylate surfactant including from about 14 to about 16 ethoxylate groups per C. sub.12-14 secondary alcohol ethoxylate surfactant molecule.
  • sub.10-14 alkyl polyethylene glycol sorbitan fatty ester surfactant includes from 0 to about 6 ethoxylate groups per C. sub.8-18 alkyl polyethylene glycol sorbitan fatty ester surfactant molecule.
  • the C. sub.12-14 secondary alcohol ethoxylate surfactant includes from about 14 to about 16 ethoxylate groups per C. sub.12-14 secondary alcohol ethoxylate surfactant molecule.
  • the cleaning composition is effective to remove chemical warfare agents from the exterior surfaces of the vehicle upon application thereto.
  • a method for cleaning exterior surfaces of a vehicle using the above cleaning composition may be applied.
  • the method includes providing a cleaning composition, applying the cleaning composition to the exterior surfaces of the vehicle, and rinsing the exterior surfaces of the vehicle with water.
  • a concrete surface may look solid from our perspective but when viewed
  • the cationic quaternary amine surfactants coupled with the alkaline pH carbonated buffer system lay the pathway for a more effective penetrating delivery of the complex cleaning chemistry embodied in D7.
  • the product behaves in ways similar to the mechanisms behind hydraulic fracturing without the high pressure pumps.
  • Alkali carbonates (potassium based) interact with the predominantly negatively biased surface
  • Hydraulic channels are opened allowing delivery of the cleaning power in the form of water, peroxide, and other formulation nonionic species.
  • D7 In its ability to penetrate/eradicate biofilms vs. traditional forms, D7 provides advantages over prior technologies as well.
  • biofilms are comprised of a secreted chemical matrix that protects pathogen colonies from intruding threats. These films have nutrient causeways, respiration causeways and transpiration causeways and their precise nature is the subject of intense inquiry.
  • the physiochemical solution properties of D7 interact in such a way as to efficiently and thoroughly disrupt those surfaces.
  • the solvency properties and the oxidation from peroxide and peracetic acid species effectively“pry” open the surface of the film and in some cases aid in the defeat of the functional causeways resulting in terminal disruption.
  • Embodiments of D7 describe an enhanced chemical formulation designed for the decontamination, disinfection and renewal of surfaces exposed to chemical, biological and toxic industrial contaminants and residues. This formula improves on prior art by expanding the efficacy spectrum, decreasing treatment time, modifying chemical properties allowing for lower effective dosage and broadening the roster of chemical agents remediated by it.
  • the formulation described herein may also be applied in variable concentrations to achieve decontamination objectives (cleaning, sanitization, disinfection, high level disinfection, mold remediation, biofilm remediation, targeted decontaminati on) .
  • Embodiments of D7 aim to incremental variants designed to perform particular tasks is the intent of this effort.
  • aspects of the invention may be formulated with a Generation 1 version of Quaternary amine (ADBAC). It is thought that broadening the type of quaternary amine may bring a benefit in either efficacy against a broader range pathogens or greater effectiveness against biofilms. Of the two, biofilm effectiveness is likely the prominent value proposition.
  • ADBAC Generation 1 version of Quaternary amine
  • D7 provides a simple roster of ingredients. D7 is not made of exotic ingredients. It is assembled with common, benign, readily available materials. Their combination produces a net effect greater than the simple sum of each.
  • D7 formulation includes:
  • Adogen 477D (50% Active) 0.05 to 2.00%
  • the Generation 5 surfactants and dimethyl dialkyl quaternary amines present an enhanced structure to the micelles developed in the D7 formulation.
  • These surfactants may modify the Gouy-Chapman-Stern layer to the point of enhanced and improved ability to more rapidly solubilize agents into the micelle body.
  • the surfactants may modify the Gouy-Chapman-Stern layer that may be tied to the speed at which an agent is decontaminated, or it might be the extent of its decontamination.
  • This embodiment of the invention may have different physical properties.
  • the efficacy profile of this version will also be different.
  • the development of the efficacy profile should be from a dilute version, perhaps a 1 to 100 dilution of the final product, up to the full version.
  • the dilute version might be considered for surfaces that are already clean and devoid of biofilm presence.
  • the concentrated version would be considered for circumstances where gross filth is more prevalent (live animal facilities, processing plants, high biofilm potential places).
  • Various embodiments of the invention for different dilutions may enable various levels of applications in addition to those disclosed in FIG. 1.
  • Pathogens toxic industrial chemicals, or other undesirable substances exist unchallenged in ambient environments except by those reactive agents common to their surroundings.
  • the natural remedies for treatment of infestations include predation by organisms, hydrolysis by water, photolysis by electromagnetic radiation, absorption by the substrate and shielding of the pathogen by environmental film to name a few. If a pathogen is soluble in water, a simple rinse may suffice. The kinetic time frame for these actions can range from the immediate to very long periods of slow transition. Delivering reactive chemical activity in the form of oxidation or nucleophillic substitution is an effective treatment strategy well known in common practice. It is the route by which numerous agents deliver their efficacious dose. Once a substance is oxidized, it is generally more susceptible to environmental decay via one or more of the aforementioned mechanisms.
  • Bleach is a water based solution whose ability to penetrate and engage pathogens is limited to the physiochemical barriers embodied on the substrate being treated. If the active cidal agent cannot come into reactive proximity with the target pathogen, nothing will happen. For this reason, disinfection and decontamination agents are formulated with substances that enable the ability overcome physiochemical barriers of interfacial tension and surface energy to deliver substances to reactive proximity. Additionally, substances that are not soluble in water may not be vulnerable to reaction based on the limited exposure to reactive conditions.
  • D7 is a formula which overcomes physiochemical barriers to deliver reactive oxidation species to pathogenic targets and by virtue of its design, aid in the ability to bring resistant substances into solution where they are then vulnerable to oxidation by the mechanisms embodied in D7.
  • This new version of the formula is an enhancement of previous versions and demonstrates a more robust and effective ability to perform decontamination/disinfection tasks.
  • D7 is a decontamination agent that delivers chemical oxidation energy in a safe, dilute form for the purpose of promoting oxidation of toxins to less harmful or totally benign breakdown products.
  • D7 chemically treats toxins by promoting oxidation and by consequence speeding up the decontamination process.
  • D7 will work to promote decontamination.
  • the application of SSDX-12 before D7 enhances the net effect by enabling of the displacement of adsorbed substances.
  • the ratio of 30: 1 equivalent dosage of D7 with SSDX-12 is desirable to achieve the targeted results with the right properties and effects on surface decontamination.

Abstract

L'invention concerne un procédé amélioré pour la décontamination de surfaces à l'aide d'une approche étagée basée sur une formule D7 ayant une mobilisation pathogène/agent/toxine suivie d'une destruction pathogène/agent/toxine sur la surface, la formule D7 ayant du SSDX -12 ajouté suivant un rapport de 30 : 1 équivalent de dose.
EP19741692.8A 2018-01-17 2019-01-17 Formulation de décontamination de surface Pending EP3740549A4 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201862618096P 2018-01-17 2018-01-17
US201862618100P 2018-01-17 2018-01-17
US201862618098P 2018-01-17 2018-01-17
US201862618104P 2018-01-17 2018-01-17
US201862618095P 2018-01-17 2018-01-17
PCT/US2018/037817 WO2018232281A1 (fr) 2017-06-15 2018-06-15 Formulation de décontamination
US16/209,960 US20190104740A1 (en) 2017-06-15 2018-12-04 Chemical and biological decontamination formulation with enhanced biocidal efficacy
PCT/US2019/014018 WO2019143821A1 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface

Publications (2)

Publication Number Publication Date
EP3740549A1 true EP3740549A1 (fr) 2020-11-25
EP3740549A4 EP3740549A4 (fr) 2021-12-22

Family

ID=67301151

Family Applications (5)

Application Number Title Priority Date Filing Date
EP19741127.5A Pending EP3740547A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface
EP19741758.7A Pending EP3740550A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de linge
EP19741840.3A Pending EP3740551A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface
EP19741692.8A Pending EP3740549A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface
EP19741521.9A Pending EP3740548A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface

Family Applications Before (3)

Application Number Title Priority Date Filing Date
EP19741127.5A Pending EP3740547A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface
EP19741758.7A Pending EP3740550A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de linge
EP19741840.3A Pending EP3740551A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP19741521.9A Pending EP3740548A4 (fr) 2018-01-17 2019-01-17 Formulation de décontamination de surface

Country Status (8)

Country Link
EP (5) EP3740547A4 (fr)
JP (5) JP7350341B2 (fr)
KR (5) KR20200133730A (fr)
CN (5) CN111868220A (fr)
AU (5) AU2019209860A1 (fr)
CA (5) CA3089006A1 (fr)
MX (5) MX2020007668A (fr)
WO (6) WO2019143825A1 (fr)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9622176D0 (en) 1996-10-24 1996-12-18 Reckitt & Colman Inc Improvements in compositions containing organic compounds
US6566574B1 (en) * 1998-06-30 2003-05-20 Sandia Corporation Formulations for neutralization of chemical and biological toxants
US7271137B2 (en) * 2000-06-29 2007-09-18 Sandia Corporation Decontamination formulations for disinfection and sterilization
FI20001563A0 (fi) * 2000-06-30 2000-06-30 Tom L Kuutti Tilanneilmaisin pelastuspalvelua varten
BR0213019B1 (pt) * 2001-10-01 2011-12-27 formulaÇço para uso na neutralizaÇço de pelo menos uma substÂncias tàxica.
US7125497B1 (en) * 2003-05-22 2006-10-24 Sandia Corporation Reactive formulations for a neutralization of toxic industrial chemicals
US7071152B2 (en) * 2003-05-30 2006-07-04 Steris Inc. Cleaning and decontamination formula for surfaces contaminated with prion-infected material
WO2005113735A1 (fr) * 2004-04-21 2005-12-01 Stepan Company Nettoyant acide pour surface solide avec composé quaternaire alkoxylé
JP5252826B2 (ja) 2007-04-17 2013-07-31 ディバーシー株式会社 硬質表面用洗浄剤組成物
US8287916B2 (en) * 2009-03-05 2012-10-16 E I Du Pont De Nemours And Company Multi-part kit system for the preparation of a disinfectant of the peracetic acid type
BR112012031189B1 (pt) * 2010-06-07 2021-10-26 Stepan Company Composição, composição biocida diluível e método de limpeza de uma superfície dura
KR101972620B1 (ko) * 2011-10-27 2019-04-25 라이온 가부시키가이샤 액체 세정제, 액체 표백성 조성물, 및 살균성 조성물
JP2015525276A (ja) * 2012-06-19 2015-09-03 ザ プロクター アンド ギャンブルカンパニー 車両の外面を洗浄するための界面活性剤組成物及び方法
WO2015089100A1 (fr) * 2013-12-10 2015-06-18 Sweigh, Inc. Système et procédé de messagerie sociale
FR3037597B1 (fr) * 2015-06-16 2019-05-31 Commissariat A L'energie Atomique Et Aux Energies Alternatives Mousse aqueuse desinfectante, son procede de preparation et ses utilisations
CA3067556A1 (fr) * 2017-06-15 2018-12-20 Decon7 Systems, Llc Formulation de decontamination

Also Published As

Publication number Publication date
AU2019209866A1 (en) 2020-08-06
JP2021511416A (ja) 2021-05-06
KR20200133730A (ko) 2020-11-30
CN111819271A (zh) 2020-10-23
CN112135896A (zh) 2020-12-25
JP7350340B2 (ja) 2023-09-26
MX2020007672A (es) 2020-11-24
CN111770981A (zh) 2020-10-13
WO2019143825A1 (fr) 2019-07-25
AU2019209868A1 (en) 2020-08-06
KR20200133727A (ko) 2020-11-30
WO2019143822A1 (fr) 2019-07-25
CA3089020A1 (fr) 2019-07-25
MX2020007669A (es) 2020-11-24
EP3740551A1 (fr) 2020-11-25
CN111868220A (zh) 2020-10-30
CA3089010A1 (fr) 2019-07-25
JP7350341B2 (ja) 2023-09-26
CA3089023A1 (fr) 2019-07-25
EP3740547A1 (fr) 2020-11-25
MX2020007667A (es) 2020-11-24
KR20200133728A (ko) 2020-11-30
CA3089006A1 (fr) 2019-07-25
WO2019143819A1 (fr) 2019-07-25
MX2020007670A (es) 2020-11-24
JP7409668B2 (ja) 2024-01-09
EP3740551A4 (fr) 2021-12-22
EP3740550A4 (fr) 2021-12-29
EP3740548A4 (fr) 2021-12-22
EP3740547A4 (fr) 2021-12-22
JP2021511418A (ja) 2021-05-06
EP3740549A4 (fr) 2021-12-22
WO2019143827A3 (fr) 2020-04-16
KR20200133726A (ko) 2020-11-30
KR20200133729A (ko) 2020-11-30
AU2019209862A1 (en) 2020-08-06
CN112135895A (zh) 2020-12-25
JP2021511417A (ja) 2021-05-06
JP2021511415A (ja) 2021-05-06
JP7409666B2 (ja) 2024-01-09
AU2019209860A1 (en) 2020-08-06
EP3740550A2 (fr) 2020-11-25
AU2019209863A1 (en) 2020-08-06
JP2021511414A (ja) 2021-05-06
WO2019143827A2 (fr) 2019-07-25
CA3089011A1 (fr) 2019-07-25
WO2020146063A1 (fr) 2020-07-16
JP7409667B2 (ja) 2024-01-09
WO2019143821A1 (fr) 2019-07-25
EP3740548A1 (fr) 2020-11-25
MX2020007668A (es) 2020-11-24

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