EP3735308A4 - Particles for use in acoustic standing wave processes - Google Patents

Particles for use in acoustic standing wave processes Download PDF

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Publication number
EP3735308A4
EP3735308A4 EP18898083.3A EP18898083A EP3735308A4 EP 3735308 A4 EP3735308 A4 EP 3735308A4 EP 18898083 A EP18898083 A EP 18898083A EP 3735308 A4 EP3735308 A4 EP 3735308A4
Authority
EP
European Patent Office
Prior art keywords
particles
standing wave
acoustic standing
wave processes
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18898083.3A
Other languages
German (de)
French (fr)
Other versions
EP3735308A1 (en
Inventor
Bart Lipkens
Krishna Kumar
Rui TOSTOES
Thomas J. Kennedy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flodesign Sonics Inc
Original Assignee
Flodesign Sonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flodesign Sonics Inc filed Critical Flodesign Sonics Inc
Publication of EP3735308A1 publication Critical patent/EP3735308A1/en
Publication of EP3735308A4 publication Critical patent/EP3735308A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/28—Mechanical auxiliary equipment for acceleration of sedimentation, e.g. by vibrators or the like
    • B01D21/283—Settling tanks provided with vibrators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/28—Mechanical auxiliary equipment for acceleration of sedimentation, e.g. by vibrators or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
    • B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
    • B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
    • B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
    • B06B1/06—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
    • B06B1/0607—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements
    • B06B1/0622—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements on one surface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
    • B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
    • B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
    • B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
    • B06B1/06—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
    • B06B1/0644—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using a single piezoelectric element
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/34—Treatment of water, waste water, or sewage with mechanical oscillations
    • C02F1/36—Treatment of water, waste water, or sewage with mechanical oscillations ultrasonic vibrations
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/40—Devices for separating or removing fatty or oily substances or similar floating material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2101/00—Nature of the contaminant
    • C02F2101/30—Organic compounds
    • C02F2101/32—Hydrocarbons, e.g. oil
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2305/00—Use of specific compounds during water treatment
EP18898083.3A 2018-01-02 2018-12-03 Particles for use in acoustic standing wave processes Withdrawn EP3735308A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862612979P 2018-01-02 2018-01-02
US201862621585P 2018-01-24 2018-01-24
PCT/US2018/063698 WO2019135843A1 (en) 2018-01-02 2018-12-03 Particles for use in acoustic standing wave processes

Publications (2)

Publication Number Publication Date
EP3735308A1 EP3735308A1 (en) 2020-11-11
EP3735308A4 true EP3735308A4 (en) 2021-09-01

Family

ID=67143902

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18898083.3A Withdrawn EP3735308A4 (en) 2018-01-02 2018-12-03 Particles for use in acoustic standing wave processes

Country Status (10)

Country Link
EP (1) EP3735308A4 (en)
JP (1) JP2021509084A (en)
KR (1) KR20200063252A (en)
CN (1) CN111587140A (en)
AU (2) AU2018399435A1 (en)
BR (1) BR112020009373A2 (en)
CA (2) CA3087498C (en)
IL (1) IL274181A (en)
SG (1) SG11202004025WA (en)
WO (1) WO2019135843A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
CN114599774A (en) * 2019-10-28 2022-06-07 弗洛设计声能学公司 Particles for acoustic processes
CN111646655B (en) * 2020-06-30 2021-08-20 广东源控环保科技有限公司 AA/O treatment process for hydrodynamic cavitation mud reduction
EP4036580A1 (en) * 2021-02-01 2022-08-03 Oxford University Innovation Limited Drug loaded cavitation agent
EP4036581A1 (en) * 2021-02-01 2022-08-03 Oxford University Innovation Limited Cavitation agent
EP4035655A1 (en) * 2021-02-01 2022-08-03 Oxford University Innovation Limited Immune modulating particles

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004017907A2 (en) * 2002-08-20 2004-03-04 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
US20110045095A1 (en) * 2008-10-08 2011-02-24 The Regents Of The University Of California Polymer-phospholipid shelled microbubbles
CN102138889A (en) * 2011-03-25 2011-08-03 中国科学院深圳先进技术研究院 Targeted drug-bearing ultrasonic microbubble and preparation method thereof
US20130022550A1 (en) * 2011-07-19 2013-01-24 Unger Evan C Microbubble Compositions, Method of Making Same, and Method Using Same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3487699B2 (en) * 1995-11-08 2004-01-19 株式会社日立製作所 Ultrasonic treatment method and apparatus
US6869591B2 (en) * 2002-03-26 2005-03-22 Barnes-Jewish Hospital Paramagnetic particles that provide improved relaxivity
GB0410015D0 (en) * 2004-05-05 2004-06-09 Univ Coventry Use
US8083068B2 (en) * 2007-04-09 2011-12-27 Los Alamos National Security, Llc Apparatus for separating particles utilizing engineered acoustic contrast capture particles
US8865003B2 (en) * 2008-09-26 2014-10-21 Abbott Laboratories Apparatus and method for separation of particles suspended in a liquid from the liquid in which they are suspended
WO2012094541A2 (en) * 2011-01-05 2012-07-12 The Regents Of The University Of California Acoustically responsive particles with decreased cavitation threshold
US9095494B2 (en) * 2011-09-30 2015-08-04 Becton, Dickinson And Company Fluid exchange methods and devices
US9950282B2 (en) * 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
EP4005604B8 (en) * 2013-09-27 2023-07-19 Exact Therapeutics As Delivery of drugs
WO2016154475A1 (en) * 2015-03-24 2016-09-29 Flodesign Sonics, Inc. Methods and apparatus for particle aggregation using acoustic standing waves
CN105535968A (en) * 2015-12-11 2016-05-04 中国科学院深圳先进技术研究院 Nanoparticle targeted delivery method based on sound field control

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004017907A2 (en) * 2002-08-20 2004-03-04 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
US20110045095A1 (en) * 2008-10-08 2011-02-24 The Regents Of The University Of California Polymer-phospholipid shelled microbubbles
CN102138889A (en) * 2011-03-25 2011-08-03 中国科学院深圳先进技术研究院 Targeted drug-bearing ultrasonic microbubble and preparation method thereof
US20130022550A1 (en) * 2011-07-19 2013-01-24 Unger Evan C Microbubble Compositions, Method of Making Same, and Method Using Same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHING-HSIANG FAN ET AL: "Ultrasound/Magnetic Targeting with SPIO-DOX-Microbubble Complex for Image-Guided Drug Delivery in Brain Tumors", THERANOSTICS, vol. 6, no. 10, 18 June 2016 (2016-06-18), AU, pages 1542 - 1556, XP055756073, ISSN: 1838-7640, DOI: 10.7150/thno.15297 *
See also references of WO2019135843A1 *

Also Published As

Publication number Publication date
IL274181A (en) 2020-06-30
AU2018399435A1 (en) 2020-05-14
CN111587140A (en) 2020-08-25
KR20200063252A (en) 2020-06-04
BR112020009373A2 (en) 2020-11-03
WO2019135843A1 (en) 2019-07-11
CA3167887A1 (en) 2019-07-11
EP3735308A1 (en) 2020-11-11
SG11202004025WA (en) 2020-05-28
CA3087498C (en) 2022-09-27
AU2022201253A1 (en) 2022-03-17
JP2021509084A (en) 2021-03-18
CA3087498A1 (en) 2019-07-11

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