EP3720443A4 - Methotrexate ophthalmic solution - Google Patents

Methotrexate ophthalmic solution Download PDF

Info

Publication number
EP3720443A4
EP3720443A4 EP19760132.1A EP19760132A EP3720443A4 EP 3720443 A4 EP3720443 A4 EP 3720443A4 EP 19760132 A EP19760132 A EP 19760132A EP 3720443 A4 EP3720443 A4 EP 3720443A4
Authority
EP
European Patent Office
Prior art keywords
methotrexate
ophthalmic solution
ophthalmic
solution
methotrexate ophthalmic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19760132.1A
Other languages
German (de)
French (fr)
Other versions
EP3720443A2 (en
Inventor
Andanayya SARGANACHARI
Sandeep SUKUMAR
Sreenivasa Reddy
Shivakumar PRADEEP
Thippeswamy AHM
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shilpa Medicare Ltd
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Publication of EP3720443A2 publication Critical patent/EP3720443A2/en
Publication of EP3720443A4 publication Critical patent/EP3720443A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
EP19760132.1A 2018-02-27 2019-02-22 Methotrexate ophthalmic solution Withdrawn EP3720443A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201841007303 2018-02-27
PCT/IB2019/051447 WO2019166926A2 (en) 2018-02-27 2019-02-22 Methotrexate ophthalmic solution

Publications (2)

Publication Number Publication Date
EP3720443A2 EP3720443A2 (en) 2020-10-14
EP3720443A4 true EP3720443A4 (en) 2021-10-20

Family

ID=67808815

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19760132.1A Withdrawn EP3720443A4 (en) 2018-02-27 2019-02-22 Methotrexate ophthalmic solution

Country Status (2)

Country Link
EP (1) EP3720443A4 (en)
WO (1) WO2019166926A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000002296A1 (en) * 2020-02-06 2021-08-06 Sifi Spa Topical ophthalmic formulations based on xanthan with reduced dosage

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010125416A1 (en) * 2009-04-27 2010-11-04 Raouf Rekik Drug delivery to the anterior and posterior segments of the eye
US20120003296A1 (en) * 2010-07-01 2012-01-05 Shantha Totada R New methods of treating dry eye syndrome
US20130324481A1 (en) * 2004-10-01 2013-12-05 Ramscor, Inc. Sustained release eye drop formulations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130324481A1 (en) * 2004-10-01 2013-12-05 Ramscor, Inc. Sustained release eye drop formulations
WO2010125416A1 (en) * 2009-04-27 2010-11-04 Raouf Rekik Drug delivery to the anterior and posterior segments of the eye
US20120003296A1 (en) * 2010-07-01 2012-01-05 Shantha Totada R New methods of treating dry eye syndrome

Also Published As

Publication number Publication date
EP3720443A2 (en) 2020-10-14
WO2019166926A2 (en) 2019-09-06

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 47/36 20060101ALN20210910BHEP

Ipc: A61K 47/18 20170101ALN20210910BHEP

Ipc: A61K 9/08 20060101ALI20210910BHEP

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