EP3715378A4 - Hemagglutinin complex protein and application thereof - Google Patents

Hemagglutinin complex protein and application thereof Download PDF

Info

Publication number
EP3715378A4
EP3715378A4 EP18880123.7A EP18880123A EP3715378A4 EP 3715378 A4 EP3715378 A4 EP 3715378A4 EP 18880123 A EP18880123 A EP 18880123A EP 3715378 A4 EP3715378 A4 EP 3715378A4
Authority
EP
European Patent Office
Prior art keywords
application
complex protein
hemagglutinin complex
hemagglutinin
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18880123.7A
Other languages
German (de)
French (fr)
Other versions
EP3715378A1 (en
Inventor
Yukako Fujinaga
Sho AMATSU
Masahiro Kinooka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osaka University NUC
Original Assignee
Kanazawa University NUC
Osaka University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanazawa University NUC, Osaka University NUC filed Critical Kanazawa University NUC
Publication of EP3715378A1 publication Critical patent/EP3715378A1/en
Publication of EP3715378A4 publication Critical patent/EP3715378A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP18880123.7A 2017-11-24 2018-11-22 Hemagglutinin complex protein and application thereof Pending EP3715378A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017226370 2017-11-24
PCT/JP2018/043249 WO2019103111A1 (en) 2017-11-24 2018-11-22 Hemagglutinin complex protein and application thereof

Publications (2)

Publication Number Publication Date
EP3715378A1 EP3715378A1 (en) 2020-09-30
EP3715378A4 true EP3715378A4 (en) 2021-09-01

Family

ID=66631636

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18880123.7A Pending EP3715378A4 (en) 2017-11-24 2018-11-22 Hemagglutinin complex protein and application thereof

Country Status (4)

Country Link
US (1) US20210122790A1 (en)
EP (1) EP3715378A4 (en)
JP (1) JP7269605B2 (en)
WO (1) WO2019103111A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023149565A1 (en) * 2022-02-07 2023-08-10 国立大学法人大阪大学 Method for inducing differentiation of pluripotent stem cells into retinal pigment epithelial cells
WO2023149566A1 (en) * 2022-02-07 2023-08-10 国立大学法人大阪大学 Differentiation induction control agent and differentiation induction stabilizing agent for pluripotent stem cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2940125A1 (en) * 2012-12-28 2015-11-04 Osaka University Method for culturing pluripotent stem cells
EP3153175A1 (en) * 2014-06-04 2017-04-12 Osaka University Adjuvant for mucosal vaccine
EP3162812A1 (en) * 2014-06-27 2017-05-03 Osaka University Mutant hemagglutinin complex protein, and method for culturing pluripotent stem cells using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514088B2 (en) * 2005-03-15 2009-04-07 Allergan, Inc. Multivalent Clostridial toxin derivatives and methods of their use
EP2773674A4 (en) * 2011-11-04 2015-04-29 Vaxinnate Corp Immunologic constructs and methods
JP2017226370A (en) 2016-06-24 2017-12-28 アイシン・エィ・ダブリュ株式会社 On-vehicle desk

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2940125A1 (en) * 2012-12-28 2015-11-04 Osaka University Method for culturing pluripotent stem cells
EP3153175A1 (en) * 2014-06-04 2017-04-12 Osaka University Adjuvant for mucosal vaccine
EP3162812A1 (en) * 2014-06-27 2017-05-03 Osaka University Mutant hemagglutinin complex protein, and method for culturing pluripotent stem cells using same

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
KWANGKOOK LEE ET AL: "Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity", PLOS PATHOGENS, vol. 9, no. 10, 10 October 2013 (2013-10-10), pages e1003690, XP055415963, DOI: 10.1371/journal.ppat.1003690 *
See also references of WO2019103111A1 *
Y. SUGAWARA ET AL: "Botulinum hemagglutinin disrupts the intercellular epithelial barrier by directly binding E-cadherin", DEVELOPMENTAL BIOLOGY, vol. 101, no. 1, 17 May 2010 (2010-05-17), AMSTERDAM, NL, pages 691 - 700, XP055247313, ISSN: 0012-1606, DOI: 10.1016/0012-1606(84)90112-X *
YO SUGAWARA ET AL: "Functional Dissection of the Clostridium botulinum Type B Hemagglutinin Complex: Identification of the Carbohydrate and E-Cadherin Binding Sites", PLOS ONE, vol. 1-4, 7, 8, 10-131-4, 6-8, 10, 119, no. 10, 1 January 2014 (2014-01-01), pages e111170 - 1, XP055247317, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0111170 *

Also Published As

Publication number Publication date
EP3715378A1 (en) 2020-09-30
JPWO2019103111A1 (en) 2020-12-03
US20210122790A1 (en) 2021-04-29
WO2019103111A1 (en) 2019-05-31
JP7269605B2 (en) 2023-05-09

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Legal Events

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Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 20200619

AK Designated contracting states

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Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20210730

RIC1 Information provided on ipc code assigned before grant

Ipc: C07K 19/00 20060101AFI20210726BHEP

Ipc: C07K 14/33 20060101ALI20210726BHEP

Ipc: C12N 5/071 20100101ALI20210726BHEP

Ipc: C12N 15/31 20060101ALI20210726BHEP

Ipc: C12N 15/62 20060101ALI20210726BHEP

Ipc: C12P 21/02 20060101ALI20210726BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: OSAKA UNIVERSITY