EP3655546A4 - Tumordetektion und -überwachung - Google Patents

Tumordetektion und -überwachung Download PDF

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Publication number
EP3655546A4
EP3655546A4 EP18918562.2A EP18918562A EP3655546A4 EP 3655546 A4 EP3655546 A4 EP 3655546A4 EP 18918562 A EP18918562 A EP 18918562A EP 3655546 A4 EP3655546 A4 EP 3655546A4
Authority
EP
European Patent Office
Prior art keywords
monitoring
tumor detection
tumor
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18918562.2A
Other languages
English (en)
French (fr)
Other versions
EP3655546A1 (de
Inventor
Anthony P. Shuber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stitch Bio LLC
Original Assignee
Stitch Bio LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/018,926 external-priority patent/US20190002964A1/en
Application filed by Stitch Bio LLC filed Critical Stitch Bio LLC
Publication of EP3655546A1 publication Critical patent/EP3655546A1/de
Publication of EP3655546A4 publication Critical patent/EP3655546A4/de
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP18918562.2A 2018-05-16 2018-10-12 Tumordetektion und -überwachung Withdrawn EP3655546A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862672217P 2018-05-16 2018-05-16
US16/018,926 US20190002964A1 (en) 2017-06-28 2018-06-26 Bodily fluid target enrichment
PCT/US2018/055648 WO2019221773A1 (en) 2018-05-16 2018-10-12 Tumor detection and monitoring

Publications (2)

Publication Number Publication Date
EP3655546A1 EP3655546A1 (de) 2020-05-27
EP3655546A4 true EP3655546A4 (de) 2021-04-07

Family

ID=68540705

Family Applications (2)

Application Number Title Priority Date Filing Date
EP18919343.6A Withdrawn EP3794139A4 (de) 2018-05-16 2018-10-03 Sequenzspezifische methylierungsanreicherung und detektion
EP18918562.2A Withdrawn EP3655546A4 (de) 2018-05-16 2018-10-12 Tumordetektion und -überwachung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18919343.6A Withdrawn EP3794139A4 (de) 2018-05-16 2018-10-03 Sequenzspezifische methylierungsanreicherung und detektion

Country Status (3)

Country Link
EP (2) EP3794139A4 (de)
CA (2) CA3100492A1 (de)
WO (2) WO2019221769A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10081829B1 (en) 2017-06-13 2018-09-25 Genetics Research, Llc Detection of targeted sequence regions
US20210155972A1 (en) * 2019-11-27 2021-05-27 Genetics Research, Llc Targeted rare allele crispr enrichment
WO2024006908A1 (en) * 2022-06-30 2024-01-04 Guardant Health, Inc. Enrichment of aberrantly methylated dna

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160017396A1 (en) * 2014-07-21 2016-01-21 Illumina, Inc. Polynucleotide enrichment using crispr-cas systems

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047787A2 (en) * 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US8916530B2 (en) * 2005-11-18 2014-12-23 Gradalis, Inc. Individualized cancer therapy
EP3633047B1 (de) * 2014-08-19 2022-12-28 Pacific Biosciences of California, Inc. Verfahren zur sequenzierung von nukleinsäuren basierend auf einer anreicherung von nukleinsäuren
US20190136248A1 (en) * 2015-05-15 2019-05-09 Pioneer Hi-Bred International, Inc. Novel guide rna/cas endonuclease systems
US20170014449A1 (en) * 2015-07-13 2017-01-19 Elwha LLC, a limited liability company of the State of Delaware Site-specific epigenetic editing
US10081829B1 (en) * 2017-06-13 2018-09-25 Genetics Research, Llc Detection of targeted sequence regions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160017396A1 (en) * 2014-07-21 2016-01-21 Illumina, Inc. Polynucleotide enrichment using crispr-cas systems

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
HEITZER ELLEN ET AL: "The potential of liquid biopsies for the early detection of cancer", NPJ PRECISION ONCOLOGY, vol. 1, no. 1, 17 October 2017 (2017-10-17), XP055775774, Retrieved from the Internet <URL:http://www.nature.com/articles/s41698-017-0039-5> DOI: 10.1038/s41698-017-0039-5 *
JONATHAN S. GOOTENBERG ET AL: "Nucleic acid detection with CRISPR-Cas13a/C2c2", SCIENCE, vol. 356, no. 6336, 28 April 2017 (2017-04-28), US, pages 438 - 442, XP055481345, ISSN: 0036-8075, DOI: 10.1126/science.aam9321 *
See also references of WO2019221773A1 *
SUTHEE RAPISUWON ET AL: "Circulating biomarkers to monitor cancer progression and treatment", COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, vol. 14, 1 January 2016 (2016-01-01), Sweden, pages 211 - 222, XP055407446, ISSN: 2001-0370, DOI: 10.1016/j.csbj.2016.05.004 *
VON BUBNOFF NIKOLAS: "Liquid Biopsy: Approaches to Dynamic Genotyping in Cancer", ONCOLOGY RESEARCH AND TREATMENT, vol. 40, no. 7-8, 1 January 2017 (2017-01-01), CH, pages 409 - 416, XP055780028, ISSN: 2296-5270, Retrieved from the Internet <URL:https://www.karger.com/Article/Pdf/478864> DOI: 10.1159/000478864 *

Also Published As

Publication number Publication date
WO2019221769A1 (en) 2019-11-21
WO2019221773A1 (en) 2019-11-21
EP3794139A1 (de) 2021-03-24
CA3069939A1 (en) 2019-11-21
EP3655546A1 (de) 2020-05-27
CA3100492A1 (en) 2019-11-21
EP3794139A4 (de) 2022-06-01

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