EP3651724A1

EP3651724A1 - Sunscreen with protection against textile spotting due to hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoates

Info

Publication number: EP3651724A1
Application number: EP18738244.5A
Authority: EP
Inventors: Shimoda Toshihiko; Janina ZIPPEL; Andreas Bleckmann; Doreen Gutzke; Kathrin Reske
Original assignee: Beiersdorf AG
Current assignee: Beiersdorf AG
Priority date: 2017-07-13
Filing date: 2018-06-29
Publication date: 2020-05-20
Also published as: DE102017212018A1; US20200163852A1; WO2019011671A1

Abstract

The invention relates to a cosmetic preparation containing hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (Inc.: diethylamino hydroxybenzoyl hexylbenzoates) which is encapsulated with cellulose acetate, and to methods and to uses of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoates (Inc.: diethylamino hydroxybenzoyl hexyl benzoates)which is encapsulated with cellulose acetate.

Description

description

Sunscreen with protection against textile staining by hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate

The present invention relates to a cosmetic preparation containing hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate encapsulated with cellulose acetate and methods and uses of hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate which is encapsulated with cellulose acetate.

The trend away from the noble paleness to the "healthy, sporty brown skin" has been unbroken for years, to achieve this, people are putting their skin on the skin

Solar radiation, as this causes a pigmentation in the sense of melanin formation. However, the ultraviolet radiation of sunlight also has a damaging effect on the skin. In addition to the acute injury (sunburn), long-term damage such as an increased risk of developing skin cancer occurs due to excessive exposure to light from the UVB range (wavelength: 280-320 nm). The excessive action of UVB and UVA radiation (wavelength: 320-400 nm) also leads to a weakening of the elastic and collagen fibers of the connective tissue. This leads to numerous

phototoxic and photoallergic reactions and leads to premature aging of the skin.

To protect the skin, therefore, a number of sunscreen filter substances has been developed which can be used in cosmetic preparations. These UVA and UVB filters are in the form of positive lists in most industrialized countries such as Appendix 7 of the

Cosmetics Regulation summarized.

However, the large number of commercially available sunscreens must not disguise the fact that these prior art preparations contain a number of

Have disadvantages.

Cosmetic preparations, such as sunscreen preparations, which are applied to the skin, come regularly (intentionally or unintentionally) with garments and Laundry items (eg towels) in contact, where they (eg as "abrasion" or because they are "sucked" by the fibers) partially adhere. In this way, depending on the nature of the ingredients, especially on bright textiles stains and discoloration. These discolorations are in particular caused by non-water-soluble UVA and broadband filters such as hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate). The stains are by washing with conventional

Hardly remove detergents and even strengthen during the washing process by interactions with ions of the wash water. It was therefore the object of the present invention to eliminate the disadvantages of the prior art and a cosmetic preparation (in particular a sunscreen) containing non-water-soluble UV-A filter such as hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: Diethylamino hydroxybenzoyl hexyl benzoate) to develop, which can be more easily washed out of the contaminated with the preparation textiles.

Surprisingly, the object is achieved by a cosmetic preparation containing hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate), which is encapsulated with cellulose acetate.

The object is further achieved by a process for facilitating the leachability of hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate) containing cosmetic formulations of textiles, characterized in that the cosmetic preparation the Hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate encapsulated in cellulose acetate encapsulated form.

The object is not least solved by the use of hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: Diethylamino hydroxybenzoyl hexyl benzoate), which is encapsulated with cellulose acetate, in cosmetic preparations to facilitate the

Washability of this UV light protection filter from textiles contaminated with the preparations.

Although the prior art is familiar with polymethylmethacrylate (PMMA) encapsulated UV filters (e.g., DE102014206147, DE102014206156, DE102014206152), these references have not been found to pave the way for the present invention. In the context of the present disclosure, the formulations relate

"Inventive", "preparation according to the invention" etc. always on the preparations according to the invention, processes and uses, ie also on preparations in which the Uses of the invention are realized and preparations with which the inventive method is realized.

The cellulose acetate-encapsulated hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate according to the invention can be prepared analogously to Example 2 of WO2017 / 037716, where hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate instead of titanium dioxide and bismuth oxychloride. It can likewise be prepared analogously to Example 2 of WO2014 / 133261, using instead of the PMMA cellulose acetate and instead of 4- (tert-butyl) -4'-methoxydibenzoylmethane, the hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate becomes. The product can be obtained from Tagra Biotechnologies LTD, Netanya.

It is advantageous according to the invention if the preparation according to the invention comprises one or more further UV filters selected from the group of compounds 4- (tert-butyl) -4'-methoxydibenzoylmethane, 2-phenylbenzimidazole-5-sulfonic acid salts, 2,4, 6-Tris [anilino (p-carbo-2'-ethyl-1 '-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone), 2,4-bis - {[4- (2 -ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine (INCI: bis-ethylhexyloxyphenol

methoxyphenyl triazines), 4,4 '- [[6 - [[4 - [[(1, 1-dimethylethyl) amino] carbonyl] phenyl] amino] -1, 3,5-triazine-2,4-diyl] diimino] bis, bis (2-ethylhexyl) benzoate (INCI: diethylhexyl butamido triazone), 2,4,6-tribiphenyl-4-yl-1,3,5-triazine (INChTris-biphenyl triazine), 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylates), 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate (INCI: homosalates), 2,2'-methylenebis (6- (2H-benzotriazol-2-yl) -4- (1, 1, 3,3-tetramethylbutyl) phenol), 2-ethylhexyl-2-cyano-3,3-diphenylacrylate, 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3 - [1,3,3,3-tetramethyl]

1- [(trimethylsilyl) oxy] -1-disiloxanyl] propyl] phenol (INCI: drometrizole trisiloxane), [(3Z) -3 - [[4 - [(Z) - [7,7-dimethyl-2-oxo] 1- (sulfomethyl) -3-bicyclo [2.2.1] heptanylidene] methyl] phenyl] methylidene] -

7,7-dimethyl-2-oxo-1-bicyclo [2.2.1] heptanyl] methanesulfonic acid (INCI: terephthalylidene dicamphor sulfonic acid), merocyanines, titanium dioxide, zinc oxide.

These further UV filters can advantageously be used in individual concentrations of 0.1 to 10% by weight, based on the total weight of the preparation.

In this case, it is preferred according to the invention if the preparation according to the invention is free from

2-hydroxy-4-methoxybenzophenone, 4-methoxycinnamic acid (2-ethylhexyl) ester 4-methoxycinnamic acid isoamyl ester and / or 3- (4-methylbenzylidene) camphor. Particular preference should be given to the use of 4-methoxycinnamic acid (2-ethylhexyl) ester, 4-methoxycinnamic acid isoamyl ester 3- (4-methylbenzylidene) camphor and 2-hydroxy-4-methoxybenzophenone.

In an alternative embodiment which is advantageous according to the invention, the preparation according to the invention is furthermore free of 2-ethylhexyl-2-cyano-3,3-diphenylacrylate (INCI:

Octocrylene). It is advantageous for the purposes of the present invention, when the preparation of the compounds hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate), which is encapsulated with cellulose acetate, in an amount of 0, 1 to 15% by weight, preferably in an amount of 0.5 to 10% by weight and more preferably in an amount of 1 to 7% by weight, based in each case on the total weight of the preparation.

The weight ratio of cellulose acetate to hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate in the capsules is according to the invention advantageously 20:80 to 60:40 and according to the invention preferably from 30:70 to 50:50 (cellulose acetate to hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate).

It is advantageous according to the invention if the preparation according to the invention is in the form of an emulsion. In this case, it is preferred according to the invention if the preparation is in the form of an oil-in-water emulsion (O / W emulsion). According to the invention, the O / W emulsion is preferably in the form of a lotion.

If the preparation according to the invention is in the form of an emulsion, then the

According to the invention advantageous embodiments characterized in that the

Preparation glyceryl stearate citrate, cetearyl alcohol, sodium cetearyl sulfate, glyceryl stearate, cetearyl sulfosuccinate, sodium stearoyl glutamate, polyglyceryl-3-methyl glucose distearate,

Stearic acid, potassium cetyl phosphate, polyglyceryl-10 stearate (INCI polyglyceryl-10 stearates) and / or polyclyceryl-2 caprate.

These ingredients are advantageously used in individual concentrations of 0, 1 to 7% by weight, based on the total weight of the preparation.

It is inventively advantageous if the preparation of the invention is free of

Polyethylene glycol, polyethylene glycol ethers and polyethylene glycol esters (so-called PEG derivatives).

Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises ethylhexylglycerol, propylene glycol, butylene glycol, 2-methylpropane-1,3-diol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 2-octanediol and / or 1 Contains 2-decanediol.

These compounds may be used alone or in combination in the invention

Preparation present. The use concentration according to the invention (individual concentration) for these ingredients is from 0.01 to 5% by weight, based on the total weight of the preparation.

In particular, the use of ethylhexylglycerol according to the invention is particularly advantageous. The advantageous use concentration according to the invention for ethylhexylglycerol is from 0.1 to 1% by weight, based on the total weight of the preparation.

It is advantageous according to the invention if the preparation according to the invention contains phenoxyethanol, 4-hydroxyacetophenone and / or ethanol.

Phenoxyethanol can be used according to the invention advantageously in a concentration of 0.01 to 0.9% by weight, based on the total weight of the preparation. According to the invention, 4-hydroxyacetophenone can advantageously be used in a concentration of 0.01 to 0.4% by weight, based on the total weight of the preparation.

According to the invention, ethanol can advantageously be used in a concentration of up to 10% by weight, based on the total weight of the preparation.

Preferred according to the invention is the use of a combination of phenoxyethanol and

Ethylhexylglycerin.

Embodiments preferred according to the invention are obtained in that the

Preparation no parabens (especially propyl and Butylparaben), and no 3-iodo-2-propinylbutylcarbamat, methylisothiazolinone, chloromethylisothiazolinone and DMDM-hydantoin contains, so is free of these ingredients.

It is inventively advantageous if the preparation of the invention selected one or more of the perfume substances from the list of compounds limonene, citral, linalool, alpha-lsomethylionon, geraniol, citronellol, 2-isobutyl-4-hydroxy-4-methyltetrahydropyran, 2-tert -Pentylcyclohexylacetate, 3-methyl-5-phenyl-1-pentanol, 7-acetyl-1,1,3,4,4,6-hexamethyltetralin, adipic diester, alpha-amylcinnamaldehyde, alpha-methylionone, amyl C, butylphenylmethyl-propionalcinnamal, Amyl salicylate, amyl cinnamyl alcohol, aniseed alcohol, benzoin, benzyl alcohol, benzyl benzoate, benzyl cinnamate, benzyl salicylate, bergamot oil, bitter orange oil, butylphenylmethylpropioal, cardamom oil, cedrol, cinnamal, cinnamyl alcohol, citronellylmethyl crotonate, citrus oil, coumarin, diethyl succinate, ethyllinalool, eugenol, ethylene brassylate, Evernia furfuracea extract, Evernia Prunastri Extract, farnesol, guaiac wood oil, geraniol, hexylcinnamal, hexyl salicylate, hydroxycitronellal, hydroxyisohexyl 3-cyclohexene ncarboxaldehyde, lavender oil, lemone oil, linayl acetate, tangerine oil, menthyl PCA, methylheptenone, nutmeg oil, rosemary oil, sweet orange oil, terpineol, tonka bean oil, triethyl citrate and / or vanillin. Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises one or more oils selected from the group of the compounds butylenes glycol dicaprylate / dicaprate, phenethyl benzoate, C12-15 alkyl benzoate, dibutyl adipate; Diisopropylsebacate, Dicaprylylcarbonate, Di-C12-13 Alkyl Tartrate, Butyloctyl Salicylate, Diethylhexyl Syringylidene Malonate, Hydragenated Castor Oil Dimerate,

Triheptanoin, C12-13 alkyl lactates, C16-17 alkyl benzoates, propylheptyl caprylates,

Caprylic / capric triglycerides, diethylhexyl 2,6-naphthalates, octyldodecanol, caprylic / capric triglycerides, ethylhexyl cocoate.

These can be in single concentrations of 0, 1 to 15% by weight, based on the

Total weight of the preparation can be used.

Embodiments of the present invention which are advantageous according to the invention are also characterized in that the preparation comprises one or more compounds selected from the group of the compounds alpha-lipoic acid, folic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine, glycyrrhetinic acid, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, β-alanine, panthenol, magnolol, honokiol, tocopheryl acetate, dihydroxyacetone; 8-hexadecene-1, 16-dicarboxylic acid, glycerylglycose, (2-hydroxyethyl) urea, vitamin E or its derivatives, hyaluronic acid and / or salts thereof and / or licochalcone A.

Embodiments of the present invention that are advantageous according to the invention are further characterized in that the preparation contains acrylate / C 10-30 alkyl acrylate crosspolymer and / or tricontanyl PVP.

Not least advantageous according to the invention is when the preparation according to the invention contains xanthan gum, tapioca starch and / or carboxymethyl cellulose.

It is also advantageous according to the invention if the preparation according to the invention comprises silica dimethyl silylates and / or talcum. The preparation of the invention may advantageously contain humectants. When

Humectants (moisturizers) are substances or mixtures of substances which give cosmetic preparations the property, after application or distribution on the skin surface, the moisture release of the horny layer (also called transepidermal water loss (TEWL) called) and / or the hydration of the horny layer positive to influence.

The aqueous phase of the preparations according to the invention may advantageously comprise customary cosmetic auxiliaries, for example alcohols, in particular those of low C number, preferably ethanol and / or isopropanol or polyols of low carbon number and their ethers, electrolytes, self-tanning and in particular one or more thickeners, which or which can be advantageously selected from the group of silica, aluminum silicates, polysaccharides or their derivatives, for. As hyaluronic acid, xanthan gum, hydroxypropylmethylcellulose and / or polyacrylates (preferably a polyacrylate from the group of so-called Carbopols, for example, Carbopols types 980, 981, 1382, 2984, 5984, each individually or in combination).

Measurement of the leachability

The washability of the stains produced by the sunscreen on textiles can be determined, for example, by the following method:

The sunscreen emulsions are examined for the formation of yellow spots on cotton textiles via an in vitro application / wash cycle. White prewashed cotton monitors (100% cotton) are used.

For this purpose, 3 mg / cm 2 of the test formulation are distributed evenly on PMMA Schönberg plates (5.0 x 5.0 cm) and transferred directly to the test textile by means of pressure. Subsequently, the stained cotton samples are air-dried for 12 hours under laboratory conditions.

After drying, a colorimetric characterization of the resulting initial staining is carried out by measuring the degree of yellowing with the colorimeter DATACOLOR 800 (Datacolor International).

Measuring geometry: d / 8 °, SCE (gloss component excluded)

Type of light / observer: D65 / 10 ° (corresponding to average daylight)

UV filtering: adapted to D65, Ganz / Griesser method

Measuring opening: LAV (30 mm diameter)

Sample background: Base paper without optical brightener, test climate: 21 ° C (± 1 ° C), 41% (± 4%) rel. Humidity.

For evaluation the change of the b-value from the CIE-Lab color measuring system is used. The B-axis characterizes the color impression yellow / blue in the CIE-Lab system, whereby positive b-values represent an increase in the yellow component. The higher the b value, the greater the yellow impression.

After the measuring process, the test cloths are washed separately in one

Washing machine) (60 ° C, 2h, Ariel Compact powder detergent, clean load).

After drying for 12 h under laboratory conditions, a colorimetric is again carried out

Characterization of the resulting stain by measuring the color values as already described with the colorimeter DATACOLOR 800 (Datacolor International).

The CIE-Lab System or L ^* a ^* b ^* Color Space is a three-dimensional measurement space containing all perceptible colors. The color space is based on the Counter color theory constructed. One of the most important features of the L ^* a ^* b ^* color model is its device independence, that is, the colors are defined independently of the nature of their generation and rendering technique.

The corresponding EU directive is DIN EN ISO 1 1664-4 "Colorimetry - Part 4: CIE 1976 L ^* a ^* b ^* Color space" The coordinates of the CIELAB plane are formed from the red / green value a and the yellow / Blue value b The brightness axis L is perpendicular to this plane According to DIN 6174, L, a and b must be written with ^* in order to distinguish against other systems, eg the "Hunter-Lab" system.

Examples

The following examples are intended to illustrate the present invention without limiting it. All amounts, proportions and percentages are, unless stated otherwise, based on the weight and the total amount or on the total weight of the preparations.

Claims

claims

Cosmetic preparation containing hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate), which is encapsulated with cellulose acetate.

Process for facilitating the washability of cosmetic preparations comprising textiles containing hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate), characterized in that the cosmetic preparation contains hexyl 2- [4- ( diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate) in cellulose acetate-encapsulated form.

Use of hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI:

Diethylamino hydroxybenzoyl hexyl benzoate), which is encapsulated with cellulose acetate, in cosmetic preparations to facilitate the washability of this UV protection filter from textiles contaminated with the preparations.

Cosmetic preparation, process or use according to one of the preceding claims, characterized in that the preparation one or more further UV filters selected from the group of compounds 4- (tert-butyl) -4'-methoxydiben- zoylmethan, 2-phenylbenzimidazole -5-sulfonic acid salts, 2,4,6-tris [anilino (p-carbo-2'-ethyl-1 '-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone),

2,4-bis - {[4- (2-ethyl-hexyl-oxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine (INCI: bis-ethylhexyloxyphenol methoxyphenyl Triazines), 4,4 '- [[6 - [[4 - [[(1, 1

dimethylethyl) amino] carbonyl] phenyl] amino] -1,

3,5-triazine-2,4-diyl] diimino] bis, bis (2-ethylhexyl) benzoate (INCI: diethylhexyl butamido triazone), 2,

4,6-Tribiphenyl-4-yl-1,3,5-triazine (INChTris-biphenyl triazine), 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate), 3,3,

5-trimethylcyclohexyl 2-hydroxybenzoate (INCI: homosalates), 2,2'-methyl-bis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) - phenol), 2-ethylhexyl-2-cyano-3,3-diphenylacrylate, 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1, 3,3,3 - tetramethyl-1 - [(trimethylsilyl) oxy] -1-disiloxanyl] propyl] phenol (INCI: drometrizole trisiloxane), [(3Z) -3 - [[4 - [(Z) - [7,7-dimethyl-2 -oxo-1 - (sulfomethyl) -3-bicyclo [2.2.1] heptanylidenes] methyl] phenyl] methylidenes] -7,7-dimethyl-2-oxo-1-bicyclo [2.2.1] heptanyl] methanesulfonic acid (INCI : Terephthalylidene dicamphor sulfonic acid), merocyanines, titanium dioxide, zinc oxide.

Cosmetic preparation, process or use according to any one of the preceding claims, characterized in that the preparation contains the hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate) which is encapsulated with cellulose acetate, in an amount of 1 to 7% by weight based on the total weight of the preparation.

6. Cosmetic preparation, method or use according to one of the preceding claims, characterized in that the preparation is in the form of an emulsion.

Cosmetic preparation, method or use according to any one of the preceding claims, characterized in that the preparation is glyceryl stearate citrate, cetearyl alcohol, sodium cetearyl sulfate, glyceryl stearate, cetearyl sulfosuccinate

Sodium stearoylglutamate, polyglyceryl-3-methylglucose distearate, polyglyceryl-3-methylglucose distearate, stearic acid, potassium cetyl phosphate, polyglyceryl-10 stearate (INCI polyglyceryl-10 stearates) and / or polyclyceryl-2 caprate.

8. Cosmetic preparation, method or use according to one of the preceding claims, characterized in that the preparation Ethylhexylglycerin,

Propylene glycol, butylene glycol, 2-methylpropane-1, 3-diol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 2-octanediol and / or 1, 2-decanediol.

9. Cosmetic preparation, method or use according to one of the preceding claims, characterized in that the preparation contains phenoxyethanol, 4-hydroxyacetophenone and / or ethanol.

10. A cosmetic preparation, method or use according to any one of the preceding claims, characterized in that the preparation of one or more of the perfume selected from the list of compounds limonene, citral, linalool, alpha-isomethylionone, geraniol, citronellol, 2-isobutyl-4 -hydroxy-4-methyltetrahydropyran, 2-tert-pentylcyclohexylacetate, 3-methyl-5-phenyl-1-pentanol, 7-acetyl-1,1,3,4,4,6-hexamethyltetralin, adipic diester, alpha-amyl-cinnamaldehyde, alpha Methyl ionone, amyl C, butylphenyl methyl propionalcinnamal, amyl salicylate, amyl cinnamyl alcohol, anisalcohol, benzoin, benzyl alcohol, benzyl benzoate, benzyl cinnamate, benzyl salicylate, bergamot oil, bitter orange oil, butylphenyl methylpropioal, cardamom oil, cedrole, cinnamal, cinnamyl alcohol, citronellylmethyl crotonate, citrus oil, coumarin,

Diethyl succinate, ethyllinalool, eugenol, ethylene brassylate, Evernia furfuracea extract, Evernia prunastri extract, farnesol, guaiac wood oil, geraniol, hexyl cinnamal,

Hexyl salicylate, hydroxycitronellal, hydroxyisohexyl 3-cyclohexene carboxaldehyde, lavender oil, lemone oil, linayl acetate, tangerine oil, menthyl PCA, methylheptenone, nutmeg oil, rosemary oil, sweet orange oil, terpineol, tonka bean oil, triethyl citrate and / or vanillin.

1 1. Cosmetic preparation, method or use according to one of

preceding claims, characterized in that the preparation is free of parabens, methylisothiazolinone, chloromethylisothiazolinone, 3-iodo-2-propynyl butylcarbamate, DMDM-hydantoin, 2-hydroxy-4-methoxybenzophenone, 4-methoxycinnamate (2-ethylhexyl) ester 4-Methoxycinntsäureisoamylester , 3- (4-methylbenzylidene) camphor.

12. A cosmetic preparation, method or use according to any one of the preceding claims, characterized in that the preparation one or more oils selected from the group of compounds butylene glycol dicaprylate / dicaprate, phenethyl benzoate, C12-15 alkyl benzoate, dibutyl adipate; Diisopropylsebacate,

Dicaprylyl carbonate, di-C12-13 alkyl tartrate, butyl octyl salicylate, diethylhexyl

Syringylidene malonates, hydrated castor oil dimerates, triheptanoin, C12-13 alkyl lactates, C16-17 alkyl benzoates, propylheptyl caprylates, caprylic / capric triglycerides, diethylhexyl 2,6-naphthalates, octyldodecanol, caprylic / capric triglycerides, ethylhexyl cocoate.

13. A cosmetic preparation, method or use according to any one of the preceding claims, characterized in that the preparation one or more

Compounds selected from the group of the compounds alpha-lipoic acid, folic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine,

Glycyrrhetinic acid, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, β-alanine, panthenol, magnolol, honokiol, tocopheryl acetate,

dihydroxyacetone; 8-hexadecene-1, 16-dicarboxylic acid, glycerylglycose, (2-hydroxyethyl) urea, vitamin E or its derivatives, hyaluronic acid and / or salts thereof and / or licochalcone A.

14. A cosmetic preparation, method or use according to any one of the preceding claims, characterized in that the preparation contains acrylate / C 10-30 alkyl acrylate crosspolymer and / or tricontanyl PVP.

Cosmetic preparation, process or use according to one of the preceding claims, characterized in that the preparation contains xanthan gum,

Tapioca starch and / or carboxymethyl cellulose contains.