EP3645489A1 - Process for manufacture of ethylene glycol - Google Patents

Process for manufacture of ethylene glycol

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Publication number
EP3645489A1
EP3645489A1 EP17915315.0A EP17915315A EP3645489A1 EP 3645489 A1 EP3645489 A1 EP 3645489A1 EP 17915315 A EP17915315 A EP 17915315A EP 3645489 A1 EP3645489 A1 EP 3645489A1
Authority
EP
European Patent Office
Prior art keywords
process according
catalyst
reaction mixture
water
ethylene glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP17915315.0A
Other languages
German (de)
French (fr)
Other versions
EP3645489A4 (en
Inventor
Peng Wu
Xinqing LU
Wenjuan ZHOU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solvay SA
East China Normal University
Original Assignee
Solvay SA
East China Normal University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay SA, East China Normal University filed Critical Solvay SA
Publication of EP3645489A1 publication Critical patent/EP3645489A1/en
Publication of EP3645489A4 publication Critical patent/EP3645489A4/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00—Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • C01B39/02—Crystalline aluminosilicate zeolites; Isomorphous compounds thereof; Direct preparation thereof; Preparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactants; After-treatment thereof
    • C01B39/026—After-treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • C07C29/106—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers of oxiranes

Definitions

  • the present invention relates to a process for the manufacture of ethylene glycol starting from ethylene oxide (EO) .
  • EO ethylene oxide
  • Ethylene Glycol (Mono-Ethylene Glycol or MEG) is an important organic chemical raw material mainly used in the production of polyester (more precisely of PET or poly-ethylene-terephthalate) and as antifreeze agent.
  • ethylene glycol production is generally made using a non-catalytic direct hydration method wherein ethylene oxide (EO) and water are reacted generally in a molar ratio of about 1: 20-22 (molar ratio) resulting in an ethylene glycol aqueous solution containing only about 10% (mass fraction) of MEG, the rest being water and by-products like diethylene glycol (DEG) and triethylene glycol (TEG) .
  • EO ethylene oxide
  • DEG diethylene glycol
  • TEG triethylene glycol
  • Increasing the amount of water used for this method can reduce the by-product formation and improve the conversion rate of ethylene oxide.
  • Zeolites of the Ti-MWW type are known to be catalysts active in epoxidation reactions: see for instance US6759540 and US7323154.
  • this kind of catalysts zeolite of the Ti-MWW type
  • this type of catalyst also allows reducing the amount of water used (typically decreasing the water/EO ratio to about 5: 1) in said synthesis hence rendering it more economical and environmentally friendly.
  • the present invention relates to a process for the manufacture of ethylene glycol starting from ethylene oxide (EO) , said process using a reaction mixture comprising EO, a Ti-MWW zeolite and water.
  • EO ethylene oxide
  • Preferred embodiments are those according to which:
  • the zeolite is modified with an organic amine, preferably with piperidine or hexamethyleneimine as disclosed in CN101003376;
  • the catalyst concentration in the reaction mixture is in the range of from 0.5 to 5 wt. %;
  • the process is performed at a temperature from 20°C to 150°C;
  • the molar ratio of water to EO is in the range of from 1 to 50.
  • the molar ratio of hydrogen peroxide to EO is preferably in the range of from 0.01 to 10;
  • the molar ratio of water to hydrogen peroxide is preferably in the range of from 5 to 50.
  • said mixture when using hydrogen peroxide in the reaction mixture, also comprises a hydrogen peroxide stabilizer like a mineral acid, preferably nitric acid, and/or HEDP (1-hydroxy ethylidene-1, 1-diphosphonic acid) .
  • a hydrogen peroxide stabilizer like a mineral acid, preferably nitric acid, and/or HEDP (1-hydroxy ethylidene-1, 1-diphosphonic acid
  • the catalyst is preferably used as a slurry catalyst or a fixed bed catalyst.
  • the zeolite is preferably mixed with a binder like silica, alumina or a mixture thereof and then shaped for instance by extrusion.
  • a hydration reaction (HR) for producing ethylene glycol is carried out under vigorous stirring in an autoclave reactor equipped with a 45 mL Telfon-inner.
  • the TS-1 catalyst was prepared according to the procedure described in U.S. Pat. No. 4,410,501.
  • the reaction mixture is immediately immersed in a pre-heated oil bath to start the reaction.
  • the reaction mixture is stirred at 40°C for 4 h, and then immediately cooled down in an ice bath to stop the reaction.
  • Both the gas and the liquid phase samples are collected and analyzed by gas chromatography (GC) using isopropanol as an internal standard.
  • GC gas chromatography
  • the gases are vented into an acetonitrile solvent for GC analysis.
  • the catalyst is removed from the reaction mixture by centrifugation and the supernatant is analyzed by GC for organic products.
  • the hydration reaction is run according to the same procedure as Comparative Example 1 except that a Ti-MWW (0.1 g) is used as a catalyst instead of a TS-1 catalyst.
  • the Ti-MWW was prepared according to a known literature procedure (Chemistry Letters, 2000: 774) .
  • the hydration reaction is run according to the same procedure as Example 2 except that the Ti-MWW catalyst was chemically treated in an aqueous solution of piperidine according to a known literature procedure (Journal of Physical Chemistry C, 2008, 112, 6132) .
  • the hydration reaction is run according to the same procedure as Example 2 except that the Ti-MWW catalyst was chemically treated in an aqueous solution of hexamethyleneimine according to a known literature procedure (Journal of Physical Chemistry C, 2008, 112, 6132) .
  • the hydration reaction is run according to the same procedure as Example 2 except that the amount of Ti-MWW is 0.2 g.
  • the hydration reaction is run according to the same procedure as Example 2 except that the amount of water is 2 g.
  • the hydration reaction is run according to the same procedure as Example 3 except that the amount of water is 2.7 g.
  • the hydration reaction is run according to the same procedure as Example 3 except that the amount of water is 2 g.
  • the hydration reaction is run according to the same procedure as Example 2 except that the reaction temperature is at 60°C.
  • the hydration reaction is run according to the same procedure as Example 2 except that 10 mmol of H2O2 is added into the reaction.
  • the hydration reaction is run according to the same procedure as Example 3 except that the amount of catalyst and the reaction time are 0.05 g and 1 h, respectively.
  • the hydration reaction is run according to the same procedure as Example 11 except that the reaction temperature is at 60°C.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

L'invention concerne un procédé de fabrication d'éthylèneglycol à partir d'oxyde d'éthylène (EO), ledit procédé utilisant un mélange réactionnel comprenant EO, une zéolite Ti-MWW et de l'eau.The invention relates to a process for producing ethylene glycol from ethylene oxide (EO), said process using a reaction mixture comprising EO, a Ti-MWW zeolite and water.

Description

    [Title established by the ISA under Rule 37.2] PROCESS FOR MANUFACTURE OF ETHYLENE GLYCOL
  • The present invention relates to a process for the manufacture of ethylene glycol starting from ethylene oxide (EO) .
  • Ethylene Glycol (Mono-Ethylene Glycol or MEG) is an important organic chemical raw material mainly used in the production of polyester (more precisely of PET or poly-ethylene-terephthalate) and as antifreeze agent.
  • At present, large-scale ethylene glycol production is generally made using a non-catalytic direct hydration method wherein ethylene oxide (EO) and water are reacted generally in a molar ratio of about 1: 20-22 (molar ratio) resulting in an ethylene glycol aqueous solution containing only about 10％ (mass fraction) of MEG, the rest being water and by-products like diethylene glycol (DEG) and triethylene glycol (TEG) . Increasing the amount of water used for this method can reduce the by-product formation and improve the conversion rate of ethylene oxide. However, it makes it necessary to set up multiple evaporators/distillation columns, increasing the equipment investment and energy consumption, which directly affects the production cost of ethylene glycol.
  • Zeolites of the Ti-MWW type are known to be catalysts active in epoxidation reactions: see for instance US6759540 and US7323154.
  • The inventors have now discovered that this kind of catalysts (zeolite of the Ti-MWW type) is also very active in the synthesis of MEG starting from EO and water (i.e. in the hydrolysis of EO to MEG) . Besides activating the reaction, this type of catalyst also allows reducing the amount of water used (typically decreasing the water/EO ratio to about 5: 1) in said synthesis hence rendering it more economical and environmentally friendly.
  • Therefore, the present invention relates to a process for the manufacture of ethylene glycol starting from ethylene oxide (EO) , said process using a reaction mixture comprising EO, a Ti-MWW zeolite and water.
  • Preferred embodiments are those according to which:
  • -the zeolite is modified with an organic amine, preferably with piperidine or hexamethyleneimine as disclosed in CN101003376；
  • -the catalyst concentration in the reaction mixture is in the range of from 0.5 to 5 wt. ％；
  • -the process is performed at a temperature from 20℃ to 150℃；
  • -the molar ratio of water to EO is in the range of from 1 to 50.
  • The use of hydrogen peroxide in the reaction mixture is preferred. In that embodiment:
  • -the molar ratio of hydrogen peroxide to EO is preferably in the range of from 0.01 to 10； and/or
  • -the molar ratio of water to hydrogen peroxide is preferably in the range of from 5 to 50.
  • Considering the fact that EO is extremely flammable and explosive, care should be taken to work in conditions outside the explosion zone.
  • In a preferred sub-embodiment, when using hydrogen peroxide in the reaction mixture, said mixture also comprises a hydrogen peroxide stabilizer like a mineral acid, preferably nitric acid, and/or HEDP (1-hydroxy ethylidene-1, 1-diphosphonic acid) .
  • In the invention, the catalyst is preferably used as a slurry catalyst or a fixed bed catalyst. Hence, the zeolite is preferably mixed with a binder like silica, alumina or a mixture thereof and then shaped for instance by extrusion.
  • The following Examples illustrate some embodiments of the present invention.
  • COMPARATIVE EXAMPLE 1
  • A hydration reaction (HR) for producing ethylene glycol is carried out under vigorous stirring in an autoclave reactor equipped with a 45 mL Telfon-inner. A TS-1 catalyst (0.1 g, Si/Ti＝50) , water (5 g) and ethylene oxide (0.44 g) are added into the reactor, and the pressure of the reactor is then raised to 1.5 MPa with nitrogen. The TS-1 catalyst was prepared according to the procedure described in U.S. Pat. No. 4,410,501. The reaction mixture is immediately immersed in a pre-heated oil bath to start the reaction. The reaction mixture is stirred at 40℃ for 4 h, and then immediately cooled down in an ice bath to stop the reaction.
  • Both the gas and the liquid phase samples are collected and analyzed by gas chromatography (GC) using isopropanol as an internal standard. The gases are vented into an acetonitrile solvent for GC analysis. The catalyst is removed from the reaction mixture by centrifugation and the supernatant is analyzed by GC for organic products.
  • EXAMPLE 2
  • The hydration reaction is run according to the same procedure as Comparative Example 1 except that a Ti-MWW (0.1 g) is used as a catalyst instead of a TS-1  catalyst. The Ti-MWW was prepared according to a known literature procedure (Chemistry Letters, 2000: 774) .
  • EXAMPLE 3
  • The hydration reaction is run according to the same procedure as Example 2 except that the Ti-MWW catalyst was chemically treated in an aqueous solution of piperidine according to a known literature procedure (Journal of Physical Chemistry C, 2008, 112, 6132) .
  • EXAMPLE 4
  • The hydration reaction is run according to the same procedure as Example 2 except that the Ti-MWW catalyst was chemically treated in an aqueous solution of hexamethyleneimine according to a known literature procedure (Journal of Physical Chemistry C, 2008, 112, 6132) .
  • EXAMPLE 5
  • The hydration reaction is run according to the same procedure as Example 2 except that the amount of Ti-MWW is 0.2 g.
  • EXAMPLE 6
  • The hydration reaction is run according to the same procedure as Example 2 except that the amount of water is 2 g.
  • EXAMPLE 7
  • The hydration reaction is run according to the same procedure as Example 3 except that the amount of water is 2.7 g.
  • EXAMPLE 8
  • The hydration reaction is run according to the same procedure as Example 3 except that the amount of water is 2 g.
  • EXAMPLE 9
  • The hydration reaction is run according to the same procedure as Example 2 except that the reaction temperature is at 60℃.
  • EXAMPLE 10
  • The hydration reaction is run according to the same procedure as Example 2 except that 10 mmol of H2O2 is added into the reaction.
  • EXAMPLE 11
  • The hydration reaction is run according to the same procedure as Example 3 except that the amount of catalyst and the reaction time are 0.05 g and 1 h, respectively.
  • EXAMPLE 12
  • The hydration reaction is run according to the same procedure as Example 11 except that the reaction temperature is at 60℃.
  • The results obtained in all these Examples are shown in Table 1 below.

Claims (10)

  1. A process for the manufacture of ethylene glycol starting from ethylene oxide (EO) ， said process using a reaction mixture comprising EO， a Ti-MWW zeolite and water.
  2. The process according to claim 1， wherein the zeolite is modified with an organic amine， preferably with piperidine or hexamethyleneimine.
  3. The process according to any of the preceding claims， wherein the catalyst concentration in the reaction mixture is in the range of from 0.5 to 5 wt. ％
  4. The process according to any of the preceding claims， wherein the process is performed at a temperature from 20℃ to 150℃.
  5. The process according to any of the preceding claims， wherein the molar ratio of water to EO is in the range of from 1 to 50.
  6. The process according to any of the preceding claims， wherein hydrogen peroxide in also present in the reaction mixture.
  7. The process according to the preceding claim， wherein the molar ratio of hydrogen peroxide to EO is preferably in the range of from 0.01 to 10.
  8. The process according to claim 6 or 7， wherein the reaction mixture also comprises a hydrogen peroxide stabilizer like a mineral acid， preferably nitric acid， and/or HEDP (1-hydroxy ethylidene-1， 1-diphosphonic acid) .
  9. The process according to any of the preceding claims， wherein the catalyst is a slurry catalyst or a fixed bed catalyst.
  10. The process according to the preceding claim， wherein the zeolite is mixed with a binder like silica， alumina or a mixture thereof and shaped by extrusion.
EP17915315.0A 2017-06-28 2017-06-28 PROCESS FOR PRODUCING ETHYLENE GLYCOL Withdrawn EP3645489A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/090500 WO2019000264A1 (en) 2017-06-28 2017-06-28 Process for manufacture of ethylene glycol

Publications (2)

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EP3645489A1 true EP3645489A1 (en) 2020-05-06
EP3645489A4 EP3645489A4 (en) 2020-12-09

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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3800488B2 (en) * 2000-05-08 2006-07-26 株式会社日本触媒 Method for producing ethylene glycol
CN100460324C (en) * 2006-09-30 2009-02-11 华东师范大学 A kind of synthetic method of alkali-modified titanium-containing molecular sieve
CN102219642B (en) * 2010-04-15 2013-12-04 中国石油化工股份有限公司 Method for producing glycol by virtue of hydration of ethylene oxide
CN102951998B (en) * 2011-08-24 2015-07-01 岳阳蓬诚科技发展有限公司 Method of preparing glycol by using one-step ethylene method

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EP3645489A4 (en) 2020-12-09
WO2019000264A1 (en) 2019-01-03

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