EP3634385A4 - Methods for the preparation of liposomes comprising drugs - Google Patents

Methods for the preparation of liposomes comprising drugs Download PDF

Info

Publication number
EP3634385A4
EP3634385A4 EP18799204.5A EP18799204A EP3634385A4 EP 3634385 A4 EP3634385 A4 EP 3634385A4 EP 18799204 A EP18799204 A EP 18799204A EP 3634385 A4 EP3634385 A4 EP 3634385A4
Authority
EP
European Patent Office
Prior art keywords
liposomes
drugs
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18799204.5A
Other languages
German (de)
French (fr)
Other versions
EP3634385A1 (en
Inventor
Indu Javeri
Kaliappanadar Nellaiappan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Curinanorx LLC
Original Assignee
Curinanorx LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/593,586 external-priority patent/US20170340563A1/en
Application filed by Curinanorx LLC filed Critical Curinanorx LLC
Publication of EP3634385A1 publication Critical patent/EP3634385A1/en
Publication of EP3634385A4 publication Critical patent/EP3634385A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
EP18799204.5A 2017-05-12 2018-05-14 Methods for the preparation of liposomes comprising drugs Pending EP3634385A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/593,586 US20170340563A1 (en) 2009-09-23 2017-05-12 Methods for the Preparation of Liposomes Comprising Drugs
PCT/US2018/032541 WO2018209342A1 (en) 2017-05-12 2018-05-14 Methods for the preparation of liposomes comprising drugs

Publications (2)

Publication Number Publication Date
EP3634385A1 EP3634385A1 (en) 2020-04-15
EP3634385A4 true EP3634385A4 (en) 2021-03-03

Family

ID=64105643

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18799204.5A Pending EP3634385A4 (en) 2017-05-12 2018-05-14 Methods for the preparation of liposomes comprising drugs

Country Status (5)

Country Link
EP (1) EP3634385A4 (en)
JP (1) JP2020519699A (en)
CN (1) CN110869006A (en)
CA (1) CA3063395A1 (en)
WO (1) WO2018209342A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113406957B (en) * 2021-05-19 2022-07-08 成都理工大学 Mobile robot autonomous navigation method based on immune deep reinforcement learning

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683714A (en) * 1991-04-19 1997-11-04 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin pharmaceutical formulation
US20040126886A1 (en) * 2000-09-25 2004-07-01 Industrial Technology Research Institute Liposome for incorporating large amounts of hydrophobic substances
US20110070292A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods For The Preparation Of Liposomes
EA022182B1 (en) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Method of producing docetaxel liposome form
WO2016134066A1 (en) * 2015-02-17 2016-08-25 Mallinckrodt Llc Modified docetaxel liposome formulations and uses thereof
US20160361259A1 (en) * 2009-09-23 2016-12-15 Indu JAVERI Methods for the Preparation of Liposomes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906476A (en) * 1988-12-14 1990-03-06 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs in lungs
JP2004524368A (en) * 2001-03-27 2004-08-12 フェアーズ ファーマシューティカル リサーチ エヌ．ヴェー． Methods and compositions for solubilizing biologically active compounds with low water solubility
JP2006248978A (en) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd New liposome preparation
CN101244039B (en) * 2008-03-20 2012-09-12 江苏先声药物研究有限公司 Novel method for preparing indissoluble medicaments liposome preparations
CN101744767B (en) * 2008-12-05 2013-02-13 中国人民解放军军事医学科学院毒物药物研究所 Thermal sensitive liposome preparation containing camptothecin antineoplastic agents
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
US20170340563A1 (en) * 2009-09-23 2017-11-30 Curirx Inc. Methods for the Preparation of Liposomes Comprising Drugs
CN103622911B (en) * 2013-11-19 2015-12-30 常州金远药业制造有限公司 A kind of hard-soluble medicine liposome preparation method

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683714A (en) * 1991-04-19 1997-11-04 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin pharmaceutical formulation
US20040126886A1 (en) * 2000-09-25 2004-07-01 Industrial Technology Research Institute Liposome for incorporating large amounts of hydrophobic substances
US20110070292A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods For The Preparation Of Liposomes
US20160361259A1 (en) * 2009-09-23 2016-12-15 Indu JAVERI Methods for the Preparation of Liposomes
EA022182B1 (en) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Method of producing docetaxel liposome form
WO2016134066A1 (en) * 2015-02-17 2016-08-25 Mallinckrodt Llc Modified docetaxel liposome formulations and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2018209342A1 *

Also Published As

Publication number Publication date
EP3634385A1 (en) 2020-04-15
WO2018209342A1 (en) 2018-11-15
CA3063395A1 (en) 2018-11-15
CN110869006A (en) 2020-03-06
JP2020519699A (en) 2020-07-02

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