EP3611505A4 - Accurate, rapid and convenient single-step disease diagnostic method using self-amplification principle of detection signal - Google Patents
Accurate, rapid and convenient single-step disease diagnostic method using self-amplification principle of detection signal Download PDFInfo
- Publication number
- EP3611505A4 EP3611505A4 EP18784065.7A EP18784065A EP3611505A4 EP 3611505 A4 EP3611505 A4 EP 3611505A4 EP 18784065 A EP18784065 A EP 18784065A EP 3611505 A4 EP3611505 A4 EP 3611505A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- rapid
- accurate
- self
- detection signal
- diagnostic method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001514 detection method Methods 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 238000003199 nucleic acid amplification method Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Inorganic Chemistry (AREA)
- Nanotechnology (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020170047841A KR101970327B1 (en) | 2017-04-13 | 2017-04-13 | A Method for Accurate, Rapid, and Convenient One-Step-Diagnosis of Disease Based on Signal Self-Enhancement |
PCT/KR2018/004313 WO2018190664A1 (en) | 2017-04-13 | 2018-04-13 | Accurate, rapid and convenient single-step disease diagnostic method using self-amplification principle of detection signal |
Publications (3)
Publication Number | Publication Date |
---|---|
EP3611505A1 EP3611505A1 (en) | 2020-02-19 |
EP3611505A4 true EP3611505A4 (en) | 2020-12-23 |
EP3611505B1 EP3611505B1 (en) | 2022-06-08 |
Family
ID=63792692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18784065.7A Active EP3611505B1 (en) | 2017-04-13 | 2018-04-13 | Accurate, rapid and convenient single-step disease diagnostic method using self-amplification principle of detection signal |
Country Status (6)
Country | Link |
---|---|
US (1) | US11668712B2 (en) |
EP (1) | EP3611505B1 (en) |
JP (1) | JP6989179B2 (en) |
KR (1) | KR101970327B1 (en) |
CN (1) | CN110573879B (en) |
WO (1) | WO2018190664A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102293984B1 (en) * | 2020-02-13 | 2021-08-26 | 셀리게인 주식회사 | 3-dimensional immunodiagnostics based on detection signal control |
WO2022234869A1 (en) * | 2021-05-03 | 2022-11-10 | 셀리게인 주식회사 | Accurate three-dimensional immunodiagnostics based on detection signal control |
KR102485429B1 (en) * | 2022-09-30 | 2023-01-09 | 주식회사 학메디칼 | Composition for diagnosis of sars-cov-2 infection and diagnostic kit using thereof |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU601273B2 (en) | 1987-03-20 | 1990-09-06 | Creative Biomolecules, Inc. | Leader sequences for the production of recombinant proteins |
EP0305500B1 (en) | 1987-03-20 | 1994-11-09 | Creative Biomolecules, Inc. | Process for the purification of recombinant polypeptides |
DE3856559T2 (en) | 1987-05-21 | 2004-04-29 | Micromet Ag | Multifunctional proteins with predetermined objectives |
KR0151305B1 (en) | 1995-12-21 | 1998-10-15 | 김태구 | Bumper molding presser for a car |
MXPA04008753A (en) * | 2002-03-12 | 2004-12-06 | Ark Therapeutics Ltd | Engineered baculoviruses and their use. |
EP1704405A1 (en) * | 2003-12-31 | 2006-09-27 | The President and Fellows of Harvard College | Assay device and method |
US7588624B2 (en) * | 2005-03-10 | 2009-09-15 | Northwestern University | Method of producing gold nanoprisms |
US20080292545A1 (en) * | 2007-04-04 | 2008-11-27 | Yuehe Lin | Functionalized Encoded Apoferritin Nanoparticles and Processes for Making and Using Same |
EP2156185B1 (en) * | 2007-06-01 | 2013-08-14 | Atonomics A/S | Bio surface acoustic wave (saw) resonator amplification with nanoparticles for detection of a target analyte |
US8088392B2 (en) * | 2007-06-18 | 2012-01-03 | Yunxu Cao | Capsid proteins and uses therefore |
CN101408496B (en) * | 2008-11-18 | 2011-08-17 | 中国检验检疫科学研究院 | Method for performing biological mark detection by atomic force microscope |
KR101027036B1 (en) * | 2009-05-28 | 2011-04-11 | 주식회사 인포피아 | Method for amplification of signal in lateral flow assay by reduction of gold ion and lateral flow assay device using the method |
GB2470939A (en) * | 2009-06-10 | 2010-12-15 | Dna Supernova Ltd | Signal amplification microspheres |
US8969619B2 (en) * | 2009-07-21 | 2015-03-03 | Ge Healthcare As | Synthesis of iodixanol in propyleneglycol |
KR20110090347A (en) | 2010-02-03 | 2011-08-10 | 고려대학교 산학협력단 | A chimeric protein, a preparation method thereof, a nanosenser fixed with the same and an application thereof |
US9925592B2 (en) * | 2010-09-24 | 2018-03-27 | Nanyang Technological University | Method for fabricating a gold nanoparticle |
US9465003B2 (en) * | 2010-12-16 | 2016-10-11 | Korea Research Institute Of Bioscience And Biotechnology | Membrane phase electrode using printing and bio-molecule detection using same |
KR101836921B1 (en) * | 2013-05-10 | 2018-03-12 | 고려대학교 산학협력단 | Recombinant self-assembling protein comprising a target-specfic peptide and use thereof |
JP6099108B2 (en) * | 2013-05-30 | 2017-03-29 | 公立大学法人大阪府立大学 | Apparatus and method for detecting a substance to be detected |
KR101495665B1 (en) | 2014-05-09 | 2015-02-26 | 한국생명공학연구원 | Method for magnetic transfer multi-fluorescence immunoassay |
KR20160051393A (en) | 2014-11-03 | 2016-05-11 | 고려대학교 산학협력단 | Protein nanoparticle linked with multiple disease specific marker epitope and ultra-sensitive method for detecting disease specific marker using it |
CN104726560B (en) * | 2015-02-11 | 2015-12-02 | 青岛大学 | A kind of colorimetry detecting zymoplasm |
KR20160117688A (en) * | 2015-03-30 | 2016-10-11 | 한국전자통신연구원 | A method for detecting biomaterials |
JP6623406B2 (en) * | 2015-08-11 | 2019-12-25 | 池田食研株式会社 | Binder |
KR20170023589A (en) * | 2015-08-24 | 2017-03-06 | 고려대학교 산학협력단 | A Method and Kit for simultaneously detecting multiple diseases based on 3D protein nanoparticle probes |
-
2017
- 2017-04-13 KR KR1020170047841A patent/KR101970327B1/en active IP Right Grant
-
2018
- 2018-04-13 EP EP18784065.7A patent/EP3611505B1/en active Active
- 2018-04-13 US US16/604,806 patent/US11668712B2/en active Active
- 2018-04-13 CN CN201880025139.8A patent/CN110573879B/en active Active
- 2018-04-13 WO PCT/KR2018/004313 patent/WO2018190664A1/en unknown
- 2018-04-13 JP JP2020506696A patent/JP6989179B2/en active Active
Non-Patent Citations (1)
Title |
---|
J-H. KWON ET AL: "Signal self-enhancement by coordinated assembly of gold nanoparticles enables accurate one-step-immunoassays", NANOSCALE, vol. 9, no. 42, 28 September 2017 (2017-09-28), United Kingdom, pages 16476 - 16484, XP055749733, ISSN: 2040-3364, DOI: 10.1039/C7NR03453A * |
Also Published As
Publication number | Publication date |
---|---|
CN110573879B (en) | 2023-05-16 |
JP6989179B2 (en) | 2022-01-05 |
EP3611505B1 (en) | 2022-06-08 |
CN110573879A (en) | 2019-12-13 |
JP2020516918A (en) | 2020-06-11 |
KR20180115480A (en) | 2018-10-23 |
WO2018190664A1 (en) | 2018-10-18 |
KR101970327B1 (en) | 2019-04-18 |
US20200124599A1 (en) | 2020-04-23 |
EP3611505A1 (en) | 2020-02-19 |
US11668712B2 (en) | 2023-06-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3644220A4 (en) | Detection of electrocardiogram signal | |
IL289907A (en) | Methods and systems for analyte detection and analysis | |
EP3171765A4 (en) | Collection and analysis of data for diagnostic purposes | |
EP3344261A4 (en) | Systems and methods for continuous health monitoring using an opto-enzymatic analyte sensor | |
EP3335036A4 (en) | Detection and monitoring of changes in metallic structures using multimode acoustic signals | |
SG10201702280YA (en) | System and method for the rapid measurement of the visual contrast sensitivity function | |
EP3270354A4 (en) | Living body detection device, living body detection method, and recording medium | |
EP3523639A4 (en) | Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same | |
EP3364670A4 (en) | Signal strength measurement method and device | |
EP3662816A4 (en) | Biometric signal-measuring apparatus equipped with trap unit for measuring biometric signal of micro-animal, and method for measuring biometric signal of micro-animal using same | |
IL254687A0 (en) | Biosensor system for the rapid detection of analytes | |
EP3449819A4 (en) | Pulse wave detection device, biological information measurement device, pulse wave detection method, and pulse wave detection program | |
EP3453320A4 (en) | Pressure pulse wave sensor, pulse wave detection device, and biological information measurement device | |
EP3151094A4 (en) | Indicator detection device and signal processing method thereof | |
EP3373494A4 (en) | Method of transmitting sounding reference signal and device utilizing same | |
EP3292395A4 (en) | Methods and systems for the detection of analytes | |
EP3443894A4 (en) | Pulse wave detection device, biological information measuring device, wearing auxiliary member of pulse wave detection device | |
TWI562758B (en) | Physiological signal measuring system and method thereof | |
EP3611505A4 (en) | Accurate, rapid and convenient single-step disease diagnostic method using self-amplification principle of detection signal | |
EP3355606A4 (en) | Method and device for detecting signal strength | |
EP3258404A4 (en) | Method and system for health condition analysis on the basis of elasticity detection device | |
EP3430990A4 (en) | Pulse wave detection device and biological information measurement device | |
EP3409208A4 (en) | Ultrasound probe and ultrasound diagnosis system including same | |
EP3370074A4 (en) | Method for detecting background noise of sensor, and device thereof | |
EP3324848A4 (en) | Sensor, sensor pad and sensor array for detecting infrasonic acoustic signals |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20191011 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20201120 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/543 20060101AFI20201116BHEP Ipc: G01N 33/569 20060101ALI20201116BHEP Ipc: G01N 33/52 20060101ALI20201116BHEP Ipc: G01N 33/553 20060101ALI20201116BHEP Ipc: G01N 33/536 20060101ALI20201116BHEP Ipc: G01N 33/58 20060101ALI20201116BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20210714 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20220211 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 1497273 Country of ref document: AT Kind code of ref document: T Effective date: 20220615 Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602018036557 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG9D |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20220608 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220908 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220909 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220908 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 1497273 Country of ref document: AT Kind code of ref document: T Effective date: 20220608 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20221010 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20221008 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602018036557 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
26N | No opposition filed |
Effective date: 20230310 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20230420 Year of fee payment: 6 Ref country code: FR Payment date: 20230424 Year of fee payment: 6 Ref country code: DE Payment date: 20230420 Year of fee payment: 6 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20230417 Year of fee payment: 6 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230413 |
|
REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20230430 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20220608 Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230430 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230430 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230430 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230413 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230413 |