EP3600485A4 - Methods for removal of toxins from blood using an extracorporeal circuit comprised of a hollow-fiber filter module and polymer sorbent in combination - Google Patents

Methods for removal of toxins from blood using an extracorporeal circuit comprised of a hollow-fiber filter module and polymer sorbent in combination Download PDF

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Publication number
EP3600485A4
EP3600485A4 EP18777490.6A EP18777490A EP3600485A4 EP 3600485 A4 EP3600485 A4 EP 3600485A4 EP 18777490 A EP18777490 A EP 18777490A EP 3600485 A4 EP3600485 A4 EP 3600485A4
Authority
EP
European Patent Office
Prior art keywords
toxins
blood
hollow
removal
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18777490.6A
Other languages
German (de)
French (fr)
Other versions
EP3600485A1 (en
Inventor
Wei-Tai Young
Tamaz Guliashvili
Andrew SCHEIRER
Josh VICHARE
Timothy KOVACS
Maryann Gruda
Thomas Golobish
Vincent Capponi
Phillip Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytosorbents Corp
Original Assignee
Cytosorbents Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytosorbents Corp filed Critical Cytosorbents Corp
Publication of EP3600485A1 publication Critical patent/EP3600485A1/en
Publication of EP3600485A4 publication Critical patent/EP3600485A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3663—Flow rate transducers; Flow integrators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/034—Lumen open in more than two directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/06—Specific process operations in the permeate stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2626—Absorption or adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/40—Adsorbents within the flow path
EP18777490.6A 2017-03-27 2018-03-22 Methods for removal of toxins from blood using an extracorporeal circuit comprised of a hollow-fiber filter module and polymer sorbent in combination Withdrawn EP3600485A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762477075P 2017-03-27 2017-03-27
PCT/US2018/023705 WO2018183072A1 (en) 2017-03-27 2018-03-22 Methods for removal of toxins from blood using an extracorporeal circuit comprised of a hollow-fiber filter module and polymer sorbent in combination

Publications (2)

Publication Number Publication Date
EP3600485A1 EP3600485A1 (en) 2020-02-05
EP3600485A4 true EP3600485A4 (en) 2021-01-06

Family

ID=63678210

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18777490.6A Withdrawn EP3600485A4 (en) 2017-03-27 2018-03-22 Methods for removal of toxins from blood using an extracorporeal circuit comprised of a hollow-fiber filter module and polymer sorbent in combination

Country Status (7)

Country Link
US (1) US11202855B2 (en)
EP (1) EP3600485A4 (en)
JP (1) JP2020523042A (en)
CN (1) CN111315424A (en)
AU (1) AU2018246007C1 (en)
CA (1) CA3057632A1 (en)
WO (1) WO2018183072A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3134900A1 (en) * 2019-04-12 2020-10-15 Uglk Science Ab Method and apparatus for reconditioning kidneys
WO2020209788A1 (en) * 2019-04-12 2020-10-15 Uglx Research Ab Method and apparatus for reconditioning organs
CA3148773A1 (en) * 2019-08-01 2021-02-04 Sigyn Therapeutics, Inc. Devices, systems and methods for the broad-spectrum reduction of pro-inflammatory cytokines in blood
US20240001017A1 (en) 2020-11-30 2024-01-04 Alteco Medical Ab Device for binding and separation of at least one component from a body fluid
WO2023097334A1 (en) * 2021-11-29 2023-06-01 Cytosorbents Corporation Improved cancer immunotherapy treatments

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013564A (en) * 1975-03-17 1977-03-22 Takeda Chemical Industries, Ltd. Multipurpose metabolic assist system
EP0073888A1 (en) * 1981-06-29 1983-03-16 Clara M. Ambrus Apparatus for removing heavy metal ions from blood
WO1995004559A1 (en) * 1993-08-10 1995-02-16 Dieter Falkenhagen Arrangement for removing substances from liquids, in particular blood
WO2006012885A1 (en) * 2004-07-30 2006-02-09 Adexter Technology Limited Filter system for treating liquids containing particles using membrane isolation and adsorption
WO2012142180A1 (en) * 2011-04-12 2012-10-18 Tianxin Wang Methods to detect and treat diseases
WO2014079680A1 (en) * 2012-11-26 2014-05-30 Gambro Lundia Ab Filter device combining beads and fibers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536412A (en) * 1992-02-06 1996-07-16 Hemocleanse, Inc. Hemofiltration and plasmafiltration devices and methods
US6287516B1 (en) * 1998-07-10 2001-09-11 Immunocept, L.L.C. Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease
JP2000167044A (en) * 1998-12-01 2000-06-20 Saitekku Kk Hemocatharsis device, and hemocatharsis equipment containing this
EP2318031A4 (en) * 2008-06-03 2012-09-12 Aethlon Medical Inc Enhanced antiviral therapy methods and devices
US9345826B2 (en) 2011-09-15 2016-05-24 Deka Products Limited Partnership Recirculating fluid filtration system
SE1200356A1 (en) 2011-10-30 2013-05-01 Kurt Nilsson Polymer-based product and use
CN102600521A (en) * 2012-03-19 2012-07-25 王天欣 Device and method for eliminating pathogens in blood
KR101638280B1 (en) * 2014-04-02 2016-07-20 조태범 Blood Purifying Apparatus

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013564A (en) * 1975-03-17 1977-03-22 Takeda Chemical Industries, Ltd. Multipurpose metabolic assist system
EP0073888A1 (en) * 1981-06-29 1983-03-16 Clara M. Ambrus Apparatus for removing heavy metal ions from blood
WO1995004559A1 (en) * 1993-08-10 1995-02-16 Dieter Falkenhagen Arrangement for removing substances from liquids, in particular blood
WO2006012885A1 (en) * 2004-07-30 2006-02-09 Adexter Technology Limited Filter system for treating liquids containing particles using membrane isolation and adsorption
WO2012142180A1 (en) * 2011-04-12 2012-10-18 Tianxin Wang Methods to detect and treat diseases
WO2014079680A1 (en) * 2012-11-26 2014-05-30 Gambro Lundia Ab Filter device combining beads and fibers

Also Published As

Publication number Publication date
CA3057632A1 (en) 2018-10-04
CN111315424A (en) 2020-06-19
US11202855B2 (en) 2021-12-21
JP2020523042A (en) 2020-08-06
AU2018246007A1 (en) 2019-10-03
WO2018183072A1 (en) 2018-10-04
US20210106743A1 (en) 2021-04-15
EP3600485A1 (en) 2020-02-05
AU2018246007C1 (en) 2022-06-23
AU2018246007B2 (en) 2022-03-17

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