EP3555115A4 - Nouveaux composés en tant qu'agents anti-mycobactériens - Google Patents

Nouveaux composés en tant qu'agents anti-mycobactériens Download PDF

Info

Publication number
EP3555115A4
EP3555115A4 EP17881453.9A EP17881453A EP3555115A4 EP 3555115 A4 EP3555115 A4 EP 3555115A4 EP 17881453 A EP17881453 A EP 17881453A EP 3555115 A4 EP3555115 A4 EP 3555115A4
Authority
EP
European Patent Office
Prior art keywords
mycobacterials
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP17881453.9A
Other languages
German (de)
English (en)
Other versions
EP3555115A1 (fr
Inventor
Richard J. Payne
Warwick John BRITTON
Anh Tran
Wendy TRAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Sydney
Original Assignee
University of Sydney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016905229A external-priority patent/AU2016905229A0/en
Application filed by University of Sydney filed Critical University of Sydney
Publication of EP3555115A1 publication Critical patent/EP3555115A1/fr
Publication of EP3555115A4 publication Critical patent/EP3555115A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0217—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -C(=O)-C-N-C(=O)-N-C-C(=O)-
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP17881453.9A 2016-12-16 2017-12-15 Nouveaux composés en tant qu'agents anti-mycobactériens Withdrawn EP3555115A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2016905229A AU2016905229A0 (en) 2016-12-16 Novel compounds as anti-mycobacterials
PCT/AU2017/051394 WO2018107236A1 (fr) 2016-12-16 2017-12-15 Nouveaux composés en tant qu'agents anti-mycobactériens

Publications (2)

Publication Number Publication Date
EP3555115A1 EP3555115A1 (fr) 2019-10-23
EP3555115A4 true EP3555115A4 (fr) 2020-08-05

Family

ID=62557690

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17881453.9A Withdrawn EP3555115A4 (fr) 2016-12-16 2017-12-15 Nouveaux composés en tant qu'agents anti-mycobactériens

Country Status (4)

Country Link
EP (1) EP3555115A4 (fr)
CN (1) CN110300759A (fr)
AU (1) AU2017377671A1 (fr)
WO (1) WO2018107236A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105755076A (zh) * 2016-04-11 2016-07-13 中国医学科学院医药生物技术研究所 利用突变合成获得sansanmycin结构类似物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482921B1 (en) * 1999-01-28 2002-11-19 Essential Therapeutics, Inc. Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105755076A (zh) * 2016-04-11 2016-07-13 中国医学科学院医药生物技术研究所 利用突变合成获得sansanmycin结构类似物的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2018107236A1 *
YUANYUAN SHI ET AL: "Improving the N-terminal diversity of sansanmycin through mutasynthesis", MICROBIAL CELL FACTORIES, vol. 15, no. 1, 6 May 2016 (2016-05-06), XP055708506, DOI: 10.1186/s12934-016-0471-1 *

Also Published As

Publication number Publication date
EP3555115A1 (fr) 2019-10-23
CN110300759A (zh) 2019-10-01
WO2018107236A1 (fr) 2018-06-21
AU2017377671A1 (en) 2019-07-11

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