EP3490694A4 - Multilayer disposable cartridge for ferrofluid-based assays and method of use - Google Patents
Multilayer disposable cartridge for ferrofluid-based assays and method of use Download PDFInfo
- Publication number
- EP3490694A4 EP3490694A4 EP17837424.5A EP17837424A EP3490694A4 EP 3490694 A4 EP3490694 A4 EP 3490694A4 EP 17837424 A EP17837424 A EP 17837424A EP 3490694 A4 EP3490694 A4 EP 3490694A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- ferrofluid
- based assays
- disposable cartridge
- multilayer disposable
- multilayer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000003556 assay Methods 0.000 title 1
- 239000011554 ferrofluid Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D19/00—Degasification of liquids
- B01D19/0031—Degasification of liquids by filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0335—Component parts; Auxiliary operations characterised by the magnetic circuit using coils
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/32—Magnetic separation acting on the medium containing the substance being separated, e.g. magneto-gravimetric-, magnetohydrostatic-, or magnetohydrodynamic separation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
- B07B1/00—Sieving, screening, sifting, or sorting solid materials using networks, gratings, grids, or the like
- B07B1/46—Constructional details of screens in general; Cleaning or heating of screens
- B07B1/4609—Constructional details of screens in general; Cleaning or heating of screens constructional details of screening surfaces or meshes
- B07B1/4636—Regulation of screen apertures
-
- G01N15/1023—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects thereof, e.g. conductivity or capacity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
- G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/082—Active control of flow resistance, e.g. flow controllers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/20—Magnetic separation whereby the particles to be separated are in solid form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
-
- G01N15/01—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G01N2015/1028—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662369163P | 2016-07-31 | 2016-07-31 | |
US201662369151P | 2016-07-31 | 2016-07-31 | |
PCT/US2017/043985 WO2018026605A1 (en) | 2016-07-31 | 2017-07-26 | Multilayer disposable cartridge for ferrofluid-based assays and method of use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3490694A1 EP3490694A1 (en) | 2019-06-05 |
EP3490694A4 true EP3490694A4 (en) | 2020-04-15 |
Family
ID=61011494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17837424.5A Withdrawn EP3490694A4 (en) | 2016-07-31 | 2017-07-26 | Multilayer disposable cartridge for ferrofluid-based assays and method of use |
Country Status (4)
Country | Link |
---|---|
US (3) | US10632463B2 (en) |
EP (1) | EP3490694A4 (en) |
CN (1) | CN109963640A (en) |
WO (1) | WO2018026605A1 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
WO2014144782A2 (en) | 2013-03-15 | 2014-09-18 | Ancera, Inc. | Systems and methods for active particle separation |
US20160299132A1 (en) | 2013-03-15 | 2016-10-13 | Ancera, Inc. | Systems and methods for bead-based assays in ferrofluids |
US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
WO2016210348A2 (en) | 2015-06-26 | 2016-12-29 | Ancera, Inc. | Background defocusing and clearing in ferrofluid-based capture assays |
US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
CN109963640A (en) | 2016-07-31 | 2019-07-02 | 安测络有限责任公司 | Multilayer disposable cassette and its application method for the measurement based on ferrofluid |
US11931739B2 (en) * | 2017-08-16 | 2024-03-19 | Simpore Inc. | Devices, methods, and kits for isolation and detection of analytes using microslit filters |
WO2019160930A1 (en) * | 2018-02-15 | 2019-08-22 | Siemens Healthcare Diagnostics Inc. | Diagnostic assay cartridge for conducting multiple diagnostic assays on a patient's single liquid test sample and methods of use related thereto |
CA3179280A1 (en) | 2020-07-14 | 2022-01-20 | Arjun Ganesan | Systems, devices and methods for analysis |
US20230332202A1 (en) | 2020-08-21 | 2023-10-19 | Ancera, Inc. | Systems, devices and methods for determing most probable number in biological sample analysis |
WO2022169905A1 (en) | 2021-02-02 | 2022-08-11 | Ancera Llc | Ferrofluid-based assay methods, and systems for parasite eggs or oocysts detection |
CN113042366B (en) * | 2021-02-27 | 2022-05-17 | 江西胜美合成材料有限公司 | Chemical material screening processing equipment |
CN113391010B (en) * | 2021-07-07 | 2023-03-24 | 安图实验仪器(郑州)有限公司 | Sample introduction method of clinical automatic analysis instrument |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3477948A (en) * | 1965-12-13 | 1969-11-11 | Inoue K | Magnetic filter and method of operating same |
US20040018611A1 (en) * | 2002-07-23 | 2004-01-29 | Ward Michael Dennis | Microfluidic devices for high gradient magnetic separation |
US20110137018A1 (en) * | 2008-04-16 | 2011-06-09 | Cynvenio Biosystems, Inc. | Magnetic separation system with pre and post processing modules |
US20130313113A1 (en) * | 2010-10-28 | 2013-11-28 | Yale University | Microfluidic Processing of Target Species in Ferrofluids |
WO2014144782A2 (en) * | 2013-03-15 | 2014-09-18 | Ancera, Inc. | Systems and methods for active particle separation |
WO2014165317A1 (en) * | 2013-03-15 | 2014-10-09 | Ancera, Inc. | Methods and systems for drug discovery and susceptibility assay in using a ferrofluid |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5439586A (en) | 1993-09-15 | 1995-08-08 | The Terry Fox Laboratory Of The British Columbia Cancer Agnecy | Magnetic filter with ordered wire array |
US6045755A (en) * | 1997-03-10 | 2000-04-04 | Trega Biosciences,, Inc. | Apparatus and method for combinatorial chemistry synthesis |
US6303389B1 (en) * | 1997-06-27 | 2001-10-16 | Immunetics | Rapid flow-through binding assay apparatus and method therefor |
US6309889B1 (en) * | 1999-12-23 | 2001-10-30 | Glaxo Wellcome Inc. | Nano-grid micro reactor and methods |
JP3956389B2 (en) * | 2002-12-11 | 2007-08-08 | 横河電機株式会社 | Hybridization method and apparatus for hybridization |
US7341652B2 (en) * | 2003-06-20 | 2008-03-11 | Groton Biosytems, Llc | Stationary capillary electrophoresis system |
US20060024690A1 (en) * | 2003-09-19 | 2006-02-02 | Kao H P | Normalization of data using controls |
US20070015289A1 (en) * | 2003-09-19 | 2007-01-18 | Kao H P | Dispenser array spotting |
US20060011305A1 (en) * | 2003-09-19 | 2006-01-19 | Donald Sandell | Automated seal applicator |
US7460223B2 (en) * | 2003-09-19 | 2008-12-02 | Applied Biosystems Inc. | Inverted orientation for a microplate |
US7417726B2 (en) * | 2003-09-19 | 2008-08-26 | Applied Biosystems Inc. | Normalization of data using controls |
US20070014694A1 (en) * | 2003-09-19 | 2007-01-18 | Beard Nigel P | High density plate filler |
US20050233472A1 (en) * | 2003-09-19 | 2005-10-20 | Kao H P | Spotting high density plate using a banded format |
US20050280811A1 (en) * | 2003-09-19 | 2005-12-22 | Donald Sandell | Grooved high density plate |
US20060029948A1 (en) * | 2003-09-19 | 2006-02-09 | Gary Lim | Sealing cover and dye compatibility selection |
US20050237528A1 (en) * | 2003-09-19 | 2005-10-27 | Oldham Mark F | Transparent heater for thermocycling |
US20060013984A1 (en) * | 2003-09-19 | 2006-01-19 | Donald Sandell | Film preparation for seal applicator |
CA2566762C (en) * | 2004-03-09 | 2010-01-19 | Pierce Biotechnology, Inc. | Dialysis device with air chamber |
US20060188399A1 (en) | 2005-02-04 | 2006-08-24 | Jadi, Inc. | Analytical sensor system for field use |
US20080219890A1 (en) * | 2005-08-04 | 2008-09-11 | Helicos Biosciences Corporation | Sample loading and recovery |
US9220831B2 (en) | 2005-10-06 | 2015-12-29 | Children's Medical Center Corporation | Device and method for combined microfluidic-micromagnetic separation of material in continuous flow |
US20090165876A1 (en) | 2005-11-22 | 2009-07-02 | Micah James Atkin | Microfluidic Structures |
US7976795B2 (en) * | 2006-01-19 | 2011-07-12 | Rheonix, Inc. | Microfluidic systems |
EP2005171B1 (en) | 2006-03-23 | 2012-08-08 | The General Hospital Corporation | Inflammation-inhibitory serum factors and uses thereof |
US8741230B2 (en) * | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
US20080000892A1 (en) * | 2006-06-26 | 2008-01-03 | Applera Corporation | Heated cover methods and technology |
EP2040983A4 (en) * | 2006-06-26 | 2011-08-03 | Life Technologies Corp | Compressible transparent sealing for open microplates |
CN101490528A (en) | 2006-07-17 | 2009-07-22 | 皇家飞利浦电子股份有限公司 | Attraction and repulsion of magnetic of magnetizable objects to and from a sensor surface |
CN201125246Y (en) * | 2006-12-31 | 2008-10-01 | 刘文韬 | Cell separation apparatus |
JP2012504956A (en) | 2008-10-10 | 2012-03-01 | セントレ ナショナル デ ラ レシェルシェ サイエンティフィーク−ディーエーイー | Cell sorting device |
US20120178645A1 (en) | 2009-06-26 | 2012-07-12 | Johannes Albert Foekens | Identifying circulating tumor cells (ctcs) using cd146 in breast cancer patients |
EP3109618B1 (en) * | 2009-12-07 | 2019-02-27 | Meso Scale Technologies, LLC. | Assay cartridge comprising a sample chamber |
EP2510351A4 (en) | 2009-12-07 | 2018-01-10 | Yale University | Label-free cellular manipulation and sorting via biocompatible ferrofluids |
US20150041396A1 (en) * | 2010-09-23 | 2015-02-12 | Battelle Memorial Institute | System and method of preconcentrating analytes in a microfluidic device |
US20140044600A1 (en) | 2011-08-12 | 2014-02-13 | Mcalister Technologies, Llc | Device for treating chemical compositions and methods for use thereof |
US10464060B2 (en) * | 2011-11-10 | 2019-11-05 | BioFare Diagnostics, LLC | Loading vials |
WO2013096804A2 (en) * | 2011-12-23 | 2013-06-27 | Abbott Point Of Care Inc | Optical assay device with pneumatic sample actuation |
KR20230069244A (en) * | 2013-03-15 | 2023-05-18 | 나노바이오심 인크. | Systems and methods for mobile device analysis of nucleic acids and proteins |
WO2015041701A1 (en) | 2013-09-23 | 2015-03-26 | Hewlett-Packard Development Company, L.P. | Validate written data |
DE102014118846B4 (en) * | 2014-12-17 | 2016-07-21 | Karlsruher Institut für Technologie | Device for measuring ultrafine particle masses |
KR20180080241A (en) * | 2015-11-02 | 2018-07-11 | 바이오파이어 다이어그노스틱스, 엘엘씨 | Sample preparation for difficult sample types |
CN105299000B (en) * | 2015-11-10 | 2018-05-29 | 中国科学院合肥物质科学研究院 | A kind of unidirectional drive microfluid pipe |
US20170297028A1 (en) * | 2016-04-15 | 2017-10-19 | Biofire Defense, Llc | Rapid Response Resistive Heater |
CN109963640A (en) | 2016-07-31 | 2019-07-02 | 安测络有限责任公司 | Multilayer disposable cassette and its application method for the measurement based on ferrofluid |
-
2017
- 2017-07-26 CN CN201780060346.2A patent/CN109963640A/en active Pending
- 2017-07-26 WO PCT/US2017/043985 patent/WO2018026605A1/en unknown
- 2017-07-26 US US15/660,606 patent/US10632463B2/en active Active
- 2017-07-26 EP EP17837424.5A patent/EP3490694A4/en not_active Withdrawn
- 2017-07-26 US US15/660,616 patent/US20180029033A1/en not_active Abandoned
-
2020
- 2020-04-27 US US16/859,431 patent/US11738337B2/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3477948A (en) * | 1965-12-13 | 1969-11-11 | Inoue K | Magnetic filter and method of operating same |
US20040018611A1 (en) * | 2002-07-23 | 2004-01-29 | Ward Michael Dennis | Microfluidic devices for high gradient magnetic separation |
US20110137018A1 (en) * | 2008-04-16 | 2011-06-09 | Cynvenio Biosystems, Inc. | Magnetic separation system with pre and post processing modules |
US20130313113A1 (en) * | 2010-10-28 | 2013-11-28 | Yale University | Microfluidic Processing of Target Species in Ferrofluids |
WO2014144782A2 (en) * | 2013-03-15 | 2014-09-18 | Ancera, Inc. | Systems and methods for active particle separation |
WO2014165317A1 (en) * | 2013-03-15 | 2014-10-09 | Ancera, Inc. | Methods and systems for drug discovery and susceptibility assay in using a ferrofluid |
Also Published As
Publication number | Publication date |
---|---|
EP3490694A1 (en) | 2019-06-05 |
US20200353466A1 (en) | 2020-11-12 |
US20180029033A1 (en) | 2018-02-01 |
US11738337B2 (en) | 2023-08-29 |
CN109963640A (en) | 2019-07-02 |
US10632463B2 (en) | 2020-04-28 |
US20180029035A1 (en) | 2018-02-01 |
WO2018026605A1 (en) | 2018-02-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3490694A4 (en) | Multilayer disposable cartridge for ferrofluid-based assays and method of use | |
EP3515478A4 (en) | Antibodies for siglec-15 and methods of use thereof | |
EP3429635A4 (en) | Anti-crispr compounds and methods of use | |
EP3504213A4 (en) | Amino-pyrrolopyrimidinone compounds and methods of use thereof | |
EP3383431A4 (en) | Anti-gitr antibodies and methods of use thereof | |
EP3548033A4 (en) | Compounds and their methods of use | |
EP3230319B8 (en) | Anti-pd-1 antibodies and methods of use thereof | |
EP3436048A4 (en) | Neoantigens and methods of their use | |
EP3383430A4 (en) | Antibodies and methods of use thereof | |
EP3169740A4 (en) | Multilayer optical adhesives and methods of making same | |
EP3280441A4 (en) | Anti-sortilin antibodies and methods of use thereof | |
EP3241414A4 (en) | Multilayer structure for accommodating electronics and related method of manufacture | |
EP3377070A4 (en) | Compounds and methods of their use | |
EP3177322A4 (en) | Anti-trem2 antibodies and methods of use thereof | |
EP3731966A4 (en) | Improved cartridge for use in in-vitro diagnostics and method of use thereof | |
EP3433613A4 (en) | Disposable fluidic cartridge and components | |
EP3110520A4 (en) | Syringe for obtaining sub-micron materials for selective assays and related methods of use | |
EP3160361A4 (en) | Analysis cartridge and method for using same | |
EP3373969A4 (en) | Glycan-interacting compounds and methods of use | |
EP3218005A4 (en) | Glycan-interacting compounds and methods of use | |
EP3655160A4 (en) | Cartridges for oral fluid analysis and methods of use | |
EP3288671A4 (en) | Disposable microfluidic cartridge | |
EP3134088A4 (en) | Bicylcic pyrazolone compounds and methods of use | |
EP3541847A4 (en) | Glycan-interacting compounds and methods of use | |
EP3090455A4 (en) | Multilayer separator and methods of manufacture and use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20190228 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20200312 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: B03C 1/32 20060101ALI20200306BHEP Ipc: B03C 1/28 20060101ALI20200306BHEP Ipc: B03C 1/033 20060101ALI20200306BHEP Ipc: B01D 19/00 20060101ALI20200306BHEP Ipc: G01N 15/00 20060101ALN20200306BHEP Ipc: B01L 3/00 20060101AFI20200306BHEP Ipc: G01N 15/10 20060101ALN20200306BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20210120 |
|
R17C | First examination report despatched (corrected) |
Effective date: 20210319 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20220212 |