EP3463556A4 - Method and system for improving stimulation of excitable tissue - Google Patents

Method and system for improving stimulation of excitable tissue Download PDF

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Publication number
EP3463556A4
EP3463556A4 EP16904183.7A EP16904183A EP3463556A4 EP 3463556 A4 EP3463556 A4 EP 3463556A4 EP 16904183 A EP16904183 A EP 16904183A EP 3463556 A4 EP3463556 A4 EP 3463556A4
Authority
EP
European Patent Office
Prior art keywords
excitable tissue
improving stimulation
stimulation
improving
excitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16904183.7A
Other languages
German (de)
French (fr)
Other versions
EP3463556A1 (en
Inventor
Jens Schouenborg
Hjalmar BJARTMARZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neuronano AB
Original Assignee
Neuronano AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/SE2016/050534 external-priority patent/WO2016195587A1/en
Priority claimed from PCT/SE2016/050698 external-priority patent/WO2017010930A1/en
Application filed by Neuronano AB filed Critical Neuronano AB
Publication of EP3463556A1 publication Critical patent/EP3463556A1/en
Publication of EP3463556A4 publication Critical patent/EP3463556A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36132—Control systems using patient feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36182—Direction of the electrical field, e.g. with sleeve around stimulating electrode
    • A61N1/36185—Selection of the electrode configuration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer
    • A61N1/37247—User interfaces, e.g. input or presentation means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36064—Epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A61N1/36085—Eating disorders or obesity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A61N1/36096—Mood disorders, e.g. depression, anxiety or panic disorder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36175—Pulse width or duty cycle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer
    • A61N1/37241—Aspects of the external programmer providing test stimulations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
EP16904183.7A 2016-06-03 2016-12-07 Method and system for improving stimulation of excitable tissue Pending EP3463556A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/SE2016/050534 WO2016195587A1 (en) 2015-06-05 2016-06-03 Method and system for improving stimulation of excitable tissue
PCT/SE2016/050698 WO2017010930A1 (en) 2015-07-10 2016-07-07 Method and system for improving stimulation of excitable tissue
PCT/SE2016/051227 WO2017209673A1 (en) 2016-06-03 2016-12-07 Method and system for improving stimulation of excitable tissue

Publications (2)

Publication Number Publication Date
EP3463556A1 EP3463556A1 (en) 2019-04-10
EP3463556A4 true EP3463556A4 (en) 2019-11-20

Family

ID=65622110

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16904183.7A Pending EP3463556A4 (en) 2016-06-03 2016-12-07 Method and system for improving stimulation of excitable tissue

Country Status (2)

Country Link
EP (1) EP3463556A4 (en)
WO (1) WO2017209673A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014207265B2 (en) 2013-01-21 2017-04-20 Cala Health, Inc. Devices and methods for controlling tremor
CN114768093A (en) 2014-06-02 2022-07-22 卡拉健康公司 Systems and methods for peripheral nerve stimulation to treat tremor
CA2988586A1 (en) 2015-06-10 2016-12-15 Cala Health, Inc. Neuromodulation system for peripheral nerve stimulation with detachable therapy unit
US10603482B2 (en) 2015-09-23 2020-03-31 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
AU2017211048B2 (en) 2016-01-21 2022-03-10 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
JP7077297B2 (en) 2016-07-08 2022-05-30 カラ ヘルス，インコーポレイテッド Systems and methods for stimulating N nerves with strictly N electrodes and improved drywall
CN110809486A (en) 2017-04-03 2020-02-18 卡拉健康公司 Peripheral neuromodulation systems, methods, and devices for treating diseases associated with overactive bladder
US11857778B2 (en) 2018-01-17 2024-01-02 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11395920B2 (en) 2019-01-22 2022-07-26 General Electric Company Brain connectivity atlas for personalized functional neurosurgery targeting and brain stimulation programming
US10905882B2 (en) 2019-01-22 2021-02-02 General Electric Company Systems and methods for predicting optimal deep brain stimulation parameters
US11273310B2 (en) 2019-01-22 2022-03-15 General Electric Company Systems and methods for predicting optimal deep brain stimulation parameters
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
JP2024508722A (en) * 2021-02-11 2024-02-28 コンフィア エスアー Electrical stimulation system and method for functional recovery and treatment of sexual disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8527059B2 (en) * 2006-03-23 2013-09-03 Medtronic, Inc. Guided programming with feedback
US20150005842A1 (en) * 2013-06-28 2015-01-01 Boston Scientific Neuromodulation Corporation Electrode selection for sub-threshold modulation therapy
EP2968952A2 (en) * 2013-03-15 2016-01-20 Boston Scientific Neuromodulation Corporation Clinical response data mapping

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7555346B1 (en) * 1999-01-07 2009-06-30 Boston Scientific Neuromodulation Corporation Implantable pulse generator having current steering means
US6909917B2 (en) * 1999-01-07 2005-06-21 Advanced Bionics Corporation Implantable generator having current steering means
US7463928B2 (en) * 2003-04-25 2008-12-09 Medtronic, Inc. Identifying combinations of electrodes for neurostimulation therapy
US7239926B2 (en) * 2003-09-15 2007-07-03 Medtronic, Inc. Selection of neurostimulator parameter configurations using genetic algorithms
US10537741B2 (en) * 2004-12-03 2020-01-21 Boston Scientific Neuromodulation Corporation System and method for choosing electrodes in an implanted stimulator device
US7231256B2 (en) * 2005-03-11 2007-06-12 Medtronic, Inc. Neurostimulation site screening
US8380321B2 (en) * 2006-02-24 2013-02-19 Medtronic, Inc. Programming interface with a cross-sectional view of a stimulation lead with complex electrode array geometry
WO2008005144A2 (en) * 2006-06-30 2008-01-10 Medtronic, Inc. Selecting electrode combinations for stimulation therapy
US8321025B2 (en) * 2006-07-31 2012-11-27 Cranial Medical Systems, Inc. Lead and methods for brain monitoring and modulation
GB2473163B (en) * 2008-06-25 2012-07-18 Advanced Neuromodulation Sys A system for electrically stimulating tissue of a patient by shifting a locus of stimulaton
US9623232B2 (en) * 2008-12-03 2017-04-18 Boston Scientific Neuromodulation Corporation Method and apparatus for identifying middle lead in a tri-lead configuration
US9067052B2 (en) * 2009-03-02 2015-06-30 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Magnetic configuration and timing scheme for transcranial magnetic stimulation
US8190250B2 (en) * 2009-10-15 2012-05-29 Boston Scientific Neuromodulation Corporation System and method for estimating volume of activation in tissue
US8532757B2 (en) * 2009-12-16 2013-09-10 Medtronic, Inc. Stimulation electrode selection
EP2600936B1 (en) * 2010-08-06 2018-09-19 Cardiac Pacemakers, Inc. User interface system for use with multipolar pacing leads
US8583237B2 (en) * 2010-09-13 2013-11-12 Cranial Medical Systems, Inc. Devices and methods for tissue modulation and monitoring
US9358398B2 (en) * 2011-05-27 2016-06-07 Boston Scientific Neuromodulation Corporation Collection of clinical data for graphical representation and analysis
US9144680B2 (en) * 2011-05-31 2015-09-29 Greatbatch Ltd. System and method of establishing a protocol for providing electrical stimulation with a stimulation system to treat a patient
WO2013046049A2 (en) * 2011-09-30 2013-04-04 Adi Mashiach Devices and methods for delivering energy as a function of condition severity

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8527059B2 (en) * 2006-03-23 2013-09-03 Medtronic, Inc. Guided programming with feedback
EP2968952A2 (en) * 2013-03-15 2016-01-20 Boston Scientific Neuromodulation Corporation Clinical response data mapping
US20150005842A1 (en) * 2013-06-28 2015-01-01 Boston Scientific Neuromodulation Corporation Electrode selection for sub-threshold modulation therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2017209673A1 *

Also Published As

Publication number Publication date
EP3463556A1 (en) 2019-04-10
WO2017209673A1 (en) 2017-12-07

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