EP3463374A4 - PROLONGED-ACTION PHARMACEUTICAL COMPOSITION BASED ON A PROTEASE INHIBITOR - Google Patents

PROLONGED-ACTION PHARMACEUTICAL COMPOSITION BASED ON A PROTEASE INHIBITOR Download PDF

Info

Publication number
EP3463374A4
EP3463374A4 EP16904195.1A EP16904195A EP3463374A4 EP 3463374 A4 EP3463374 A4 EP 3463374A4 EP 16904195 A EP16904195 A EP 16904195A EP 3463374 A4 EP3463374 A4 EP 3463374A4
Authority
EP
European Patent Office
Prior art keywords
pharmaceutical composition
protease inhibitor
long acting
acting pharmaceutical
long
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16904195.1A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3463374A1 (en
Inventor
James Nienyuan CHANG
Hsiang-Fa Liang
Meng-Hsin Chen
Kuei-Ling Kuo
An-Chieh Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taimed Biologics Inc
Original Assignee
Taimed Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taimed Biologics Inc filed Critical Taimed Biologics Inc
Publication of EP3463374A1 publication Critical patent/EP3463374A1/en
Publication of EP3463374A4 publication Critical patent/EP3463374A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP16904195.1A 2016-05-31 2016-05-31 PROLONGED-ACTION PHARMACEUTICAL COMPOSITION BASED ON A PROTEASE INHIBITOR Withdrawn EP3463374A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2016/035029 WO2017209732A1 (en) 2016-05-31 2016-05-31 A long acting pharmaceutical composition of protease inhibitor

Publications (2)

Publication Number Publication Date
EP3463374A1 EP3463374A1 (en) 2019-04-10
EP3463374A4 true EP3463374A4 (en) 2020-01-22

Family

ID=60478957

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16904195.1A Withdrawn EP3463374A4 (en) 2016-05-31 2016-05-31 PROLONGED-ACTION PHARMACEUTICAL COMPOSITION BASED ON A PROTEASE INHIBITOR

Country Status (4)

Country Link
EP (1) EP3463374A4 (ja)
JP (1) JP6704058B2 (ja)
CN (1) CN109475563A (ja)
WO (1) WO2017209732A1 (ja)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6068858A (en) * 1997-02-13 2000-05-30 Elan Pharma International Limited Methods of making nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8145198A (en) * 1997-06-16 1999-01-04 Vertex Pharmaceuticals Incorporated Methods of increasing the bioavailability of stable crystal polymorphs of a compound
US7388008B2 (en) * 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
WO2006114001A1 (en) * 2005-04-27 2006-11-02 Ambrilia Biopharma Inc. Method for improving pharmacokinetics of protease inhibitors and protease inhibitor precursors
ES2452718T3 (es) * 2005-11-30 2014-04-02 Taimed Biologics, Inc. Profármacos a base de lisina de inhibidores de la aspartil proteasa y procesos para su preparación
WO2007138069A1 (en) * 2006-05-30 2007-12-06 Tibotec Pharmaceuticals Ltd. Lysine related derivatives as hiv aspartyl protease inhibitors
PL2040671T3 (pl) * 2006-06-23 2018-08-31 Janssen Sciences Ireland Uc Wodne zawiesiny TMC278
EP2109461A2 (en) * 2006-07-17 2009-10-21 Ambrilia Biopharma Inc. Method for improving pharmacokinetics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6068858A (en) * 1997-02-13 2000-05-30 Elan Pharma International Limited Methods of making nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DAS MALAY K ET AL: "Nano-ART and NeuroAIDS", DRUG DELIVERY AND TRANSLATIONAL RESEARCH, SPRINGER, GERMANY, vol. 6, no. 5, 2 May 2016 (2016-05-02), pages 452 - 472, XP036042525, ISSN: 2190-393X, [retrieved on 20160502], DOI: 10.1007/S13346-016-0293-Z *
LALIT KUMAR ET AL: "Nanotechnology: A magic bullet for HIV AIDS treatment", ARTIFICIAL CELLS, NANOMEDICINE AND BIOTECHNOLOGY, vol. 43, no. 2, 25 February 2014 (2014-02-25), US, pages 71 - 86, XP055653795, ISSN: 2169-1401, DOI: 10.3109/21691401.2014.883400 *
See also references of WO2017209732A1 *

Also Published As

Publication number Publication date
EP3463374A1 (en) 2019-04-10
CN109475563A (zh) 2019-03-15
JP6704058B2 (ja) 2020-06-03
JP2019510002A (ja) 2019-04-11
WO2017209732A1 (en) 2017-12-07

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