EP3434681A4 - Curcumin-boron complex and pharmaceutical containing same - Google Patents

Curcumin-boron complex and pharmaceutical containing same Download PDF

Info

Publication number
EP3434681A4
EP3434681A4 EP17770214.9A EP17770214A EP3434681A4 EP 3434681 A4 EP3434681 A4 EP 3434681A4 EP 17770214 A EP17770214 A EP 17770214A EP 3434681 A4 EP3434681 A4 EP 3434681A4
Authority
EP
European Patent Office
Prior art keywords
curcumin
containing same
boron complex
pharmaceutical containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP17770214.9A
Other languages
German (de)
French (fr)
Other versions
EP3434681A1 (en
EP3434681B1 (en
Inventor
Motomu Kanai
Yohei Soma
Jizhi Ni
Atsuhiko TANIGUCHI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Science and Technology Agency
Original Assignee
Japan Science and Technology Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Science and Technology Agency filed Critical Japan Science and Technology Agency
Publication of EP3434681A1 publication Critical patent/EP3434681A1/en
Publication of EP3434681A4 publication Critical patent/EP3434681A4/en
Application granted granted Critical
Publication of EP3434681B1 publication Critical patent/EP3434681B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP17770214.9A 2016-03-22 2017-03-21 Curcumin-boron complex and pharmaceutical containing same Active EP3434681B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016056615 2016-03-22
PCT/JP2017/011232 WO2017164172A1 (en) 2016-03-22 2017-03-21 Curcumin-boron complex and pharmaceutical containing same

Publications (3)

Publication Number Publication Date
EP3434681A1 EP3434681A1 (en) 2019-01-30
EP3434681A4 true EP3434681A4 (en) 2019-10-30
EP3434681B1 EP3434681B1 (en) 2023-05-10

Family

ID=59899637

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17770214.9A Active EP3434681B1 (en) 2016-03-22 2017-03-21 Curcumin-boron complex and pharmaceutical containing same

Country Status (5)

Country Link
US (1) US10669287B2 (en)
EP (1) EP3434681B1 (en)
JP (1) JP6846052B2 (en)
CN (1) CN108884112B (en)
WO (1) WO2017164172A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114031635B (en) * 2021-12-14 2024-02-13 洛阳师范学院 Difluoroborocurcumin derivative and preparation method and application thereof
WO2023120277A1 (en) * 2021-12-23 2023-06-29 三井化学株式会社 Organic electroluminescent element, thin film, compound, delayed fluorescence-emitting body, and organic semiconductor laser

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679864A (en) 1995-11-03 1997-10-21 Gene Print Inc. Process for the synthesis of curcumin-related compounds
US20110208064A1 (en) 2008-07-31 2011-08-25 Ran Chongzhao Curcumin Derivatives for Amyloid-Beta Plaque Imaging
WO2011014648A2 (en) 2009-07-31 2011-02-03 The General Hospital Corporation METHODS AND SYSTEM FOR DETECTING SOLUBLE AMYLOID-β
ES2837014T3 (en) 2012-05-08 2021-06-29 Asac Compania De Biotecnologia E Investig Sa Procedure for the synthesis of curcumin
WO2014025808A1 (en) 2012-08-06 2014-02-13 The General Hospital Corporation Curcumin analogs
WO2015034996A1 (en) 2013-09-06 2015-03-12 The General Hospital Corporation Imaging brown adipose tissue with curcumin derivatives
JP6562361B2 (en) 2014-07-16 2019-08-21 国立研究開発法人科学技術振興機構 Benzothiazole compound and pharmaceutical containing the same
US10188671B2 (en) 2015-03-06 2019-01-29 Japan Science And Technology Agency Boron-dipyrrin complex and medicament containing the same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
OKAMOTO ET AL: "Inactivation of myostatin by photo-oxygenation using catalyst-functionalized peptides - Chemical Communications (RSC Publishing)", CHEMICAL COMMUNICATIONS; ISSUE 62, 2019, 1 January 2019 (2019-01-01), XP055622026, Retrieved from the Internet <URL:https://pubs.rsc.org/en/content/articlelanding/2019/CC/c9cc04368c#|divAbstract> [retrieved on 20190913] *
See also references of WO2017164172A1 *
SIMON WANNINGER ET AL: "Metal complexes of curcumin - synthetic strategies, structures and medicinal applications", CHEMICAL SOCIETY REVIEWS, vol. 44, no. 15, 1 January 2015 (2015-01-01), UK, pages 4986 - 5002, XP055432857, ISSN: 0306-0012, DOI: 10.1039/C5CS00088B *

Also Published As

Publication number Publication date
CN108884112A (en) 2018-11-23
JPWO2017164172A1 (en) 2019-02-14
US20190100537A1 (en) 2019-04-04
EP3434681A1 (en) 2019-01-30
CN108884112B (en) 2021-03-02
JP6846052B2 (en) 2021-03-24
EP3434681B1 (en) 2023-05-10
WO2017164172A1 (en) 2017-09-28
US10669287B2 (en) 2020-06-02

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